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The map label for this gene is pdxA [H]

Identifier: 152969675

GI number: 152969675

Start: 1272649

End: 1273659

Strand: Direct

Name: pdxA [H]

Synonym: KPN_01121

Alternate gene names: 152969675

Gene position: 1272649-1273659 (Clockwise)

Preceding gene: 152969672

Following gene: 152969676

Centisome position: 23.94

GC content: 55.39

Gene sequence:

>1011_bases
ATGATGTCAGCAGAGAAAAAACCCGTTGTGGCGATTACCATTGGCGATCCGGCAGGGATCGGCCCGGAGATCACCGTGGC
CACCATGATGGACAAAAGCGTGTATGACGAGTGCAAACCGTTCCTGATCGGCTCGGTACCGATTATCAGCCGGGCGATGA
AAATCATGGGCTGCGATTTTGCTATCCATAAAATTGCCCATCCGCAGGAGGCCCGTTTTAGCTGGGGGACGTTGGATGTT
CTGGAAACTGGCGACTACGATTGCGACAGTATCGAATGGGGCAAGGTGCAGAAACTGGCGGGGCAAATGTCGCTGGACTA
TGTGATGAAGTCGATCGAGCTGGGCAAAGCGGGGCTGATCGACGTGGTCTCTACTGCACCAATTCATAAGGAAGCCATCA
AGCTGGCAGGATGTAAGCTCCCGGGCCATACCGAAATCTATCAGGTGGAAACCCAATCTGATTACGGTCTGACCATGTTC
CACGTCCACAACCTGCGCGTCTTCTTCGTGAGCCGTCATATGGCGCTAAAAGCAGCCTGTGACTATGCCAACAAAGCGCG
AGTGCTGGCCTGCGTTCAGCAGATCCACCATGAATTTACCGCCCTGAACATCAAAAATCCGCGCATTGCCGTGGCCGCCC
TGAACCCGCATGGCTCCGACAATGGTCTGTTTGGTCACGAAGAGGCTGACAATCTGATCCCGGCGGTGAAAGCGGCCCAG
GAGATGGGGATCAACGCTATCGGGCCGGTTCCGGCCGATTCCGTGTTCCATCTCGGCAAACAGGGGCGCTACGACGCCAT
TCTCTCGCTGTATCACGATCAGGGGCATATTGCCTGCAAAACCCTCGACTTTGAACGTTCGATCACCATTACCTTCGGCC
TGCCGTTTATGCGCAGCTCCGTCGACCATGGGACGGCGTTTGATATCGCCGGTACCGGTAAGGCGGGTACCGTCAGTATG
CTGGAGTCGACGCTGGTGGCGGCCCGTTACTGGAAAATGAAGCATCAATAA

Upstream 100 bases:

>100_bases
TGATCTTCATCACTCATGGCGGCTCATTCATCAGGTAATGTTTTGAGCATATGATTTGATAGTGAACATATGAACAATCA
ACTGAAAAAATGAGAGGCGC

Downstream 100 bases:

>100_bases
TCGCTGAGGTTCATGCGAATCACGAGGACAGAGAAATGGAAAAACATCTGTTGATTAGCAAGGGCTGTAAGGGCTGGGGC
GGGCCGCTGACTATCACGCC

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MMSAEKKPVVAITIGDPAGIGPEITVATMMDKSVYDECKPFLIGSVPIISRAMKIMGCDFAIHKIAHPQEARFSWGTLDV
LETGDYDCDSIEWGKVQKLAGQMSLDYVMKSIELGKAGLIDVVSTAPIHKEAIKLAGCKLPGHTEIYQVETQSDYGLTMF
HVHNLRVFFVSRHMALKAACDYANKARVLACVQQIHHEFTALNIKNPRIAVAALNPHGSDNGLFGHEEADNLIPAVKAAQ
EMGINAIGPVPADSVFHLGKQGRYDAILSLYHDQGHIACKTLDFERSITITFGLPFMRSSVDHGTAFDIAGTGKAGTVSM
LESTLVAARYWKMKHQ

Sequences:

>Translated_336_residues
MMSAEKKPVVAITIGDPAGIGPEITVATMMDKSVYDECKPFLIGSVPIISRAMKIMGCDFAIHKIAHPQEARFSWGTLDV
LETGDYDCDSIEWGKVQKLAGQMSLDYVMKSIELGKAGLIDVVSTAPIHKEAIKLAGCKLPGHTEIYQVETQSDYGLTMF
HVHNLRVFFVSRHMALKAACDYANKARVLACVQQIHHEFTALNIKNPRIAVAALNPHGSDNGLFGHEEADNLIPAVKAAQ
EMGINAIGPVPADSVFHLGKQGRYDAILSLYHDQGHIACKTLDFERSITITFGLPFMRSSVDHGTAFDIAGTGKAGTVSM
LESTLVAARYWKMKHQ
>Mature_336_residues
MMSAEKKPVVAITIGDPAGIGPEITVATMMDKSVYDECKPFLIGSVPIISRAMKIMGCDFAIHKIAHPQEARFSWGTLDV
LETGDYDCDSIEWGKVQKLAGQMSLDYVMKSIELGKAGLIDVVSTAPIHKEAIKLAGCKLPGHTEIYQVETQSDYGLTMF
HVHNLRVFFVSRHMALKAACDYANKARVLACVQQIHHEFTALNIKNPRIAVAALNPHGSDNGLFGHEEADNLIPAVKAAQ
EMGINAIGPVPADSVFHLGKQGRYDAILSLYHDQGHIACKTLDFERSITITFGLPFMRSSVDHGTAFDIAGTGKAGTVSM
LESTLVAARYWKMKHQ

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=333, Percent_Identity=31.2312312312312, Blast_Score=161, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 36667; Mature: 36667

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSAEKKPVVAITIGDPAGIGPEITVATMMDKSVYDECKPFLIGSVPIISRAMKIMGCDF
CCCCCCCCEEEEEECCCCCCCCCEEEEEHHHHHHHHHCCCEEECCCHHHHHHHHHHCCCH
AIHKIAHPQEARFSWGTLDVLETGDYDCDSIEWGKVQKLAGQMSLDYVMKSIELGKAGLI
HHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCE
DVVSTAPIHKEAIKLAGCKLPGHTEIYQVETQSDYGLTMFHVHNLRVFFVSRHMALKAAC
EHHCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEEECEEEEEEEHHHHHHHHH
DYANKARVLACVQQIHHEFTALNIKNPRIAVAALNPHGSDNGLFGHEEADNLIPAVKAAQ
CCCCHHHHHHHHHHHHHHHEEEEECCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
EMGINAIGPVPADSVFHLGKQGRYDAILSLYHDQGHIACKTLDFERSITITFGLPFMRSS
HCCCCCCCCCCCHHHHHCCCCCCHHHEEEEEECCCCEEEEEEECCCEEEEEECCHHHHCC
VDHGTAFDIAGTGKAGTVSMLESTLVAARYWKMKHQ
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMSAEKKPVVAITIGDPAGIGPEITVATMMDKSVYDECKPFLIGSVPIISRAMKIMGCDF
CCCCCCCCEEEEEECCCCCCCCCEEEEEHHHHHHHHHCCCEEECCCHHHHHHHHHHCCCH
AIHKIAHPQEARFSWGTLDVLETGDYDCDSIEWGKVQKLAGQMSLDYVMKSIELGKAGLI
HHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCE
DVVSTAPIHKEAIKLAGCKLPGHTEIYQVETQSDYGLTMFHVHNLRVFFVSRHMALKAAC
EHHCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEEECEEEEEEEHHHHHHHHH
DYANKARVLACVQQIHHEFTALNIKNPRIAVAALNPHGSDNGLFGHEEADNLIPAVKAAQ
CCCCHHHHHHHHHHHHHHHEEEEECCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
EMGINAIGPVPADSVFHLGKQGRYDAILSLYHDQGHIACKTLDFERSITITFGLPFMRSS
HCCCCCCCCCCCHHHHHCCCCCCHHHEEEEEECCCCEEEEEEECCCEEEEEECCHHHHCC
VDHGTAFDIAGTGKAGTVSMLESTLVAARYWKMKHQ
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA