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The map label for this gene is ycfW [H]

Identifier: 152969669

GI number: 152969669

Start: 1267108

End: 1268352

Strand: Direct

Name: ycfW [H]

Synonym: KPN_01115

Alternate gene names: 152969669

Gene position: 1267108-1268352 (Clockwise)

Preceding gene: 152969668

Following gene: 152969670

Centisome position: 23.84

GC content: 58.63

Gene sequence:

>1245_bases
ATGGCGTCTCCGTTATCGTTACTGATTGCATTGCGTTTCAGCCGCGGCCGGCGGCGCGGCGGCATGGTGTCGCTGATCTC
GGTGATCTCCACCATCGGCATTGCGCTGGGGGTGGCGGTGCTGATCGTCGGCCTCAGCGCGATGAACGGCTTTGAGCGCG
AGCTGAATAACCGCGTGCTGGCGGTGGTACCGCATGGCGAGATCGAACCCGTGAATCAGCCGTGGAATAACTGGCAGGAA
GCGCTGGCGAAGGTGCAGAAGGTGAAGGGGATTGTCGCGGCAGCGCCCTATATTAACTTCACCGGCCTGGTGGAGAGCGG
CAGCAATATGCGCGCCATCCAGGTGAAAGGCGTCGACCCGCAGCAGGAGAGCCAGCTCAGCGCGCTGCCTACCTTTGTGC
AGAATAACGCGTGGGCCGGATTCAAGGCTGGCGAACAGCAAGTGATCCTGGGCAAAGGGGTCGCCGATGCCCTGCACGTG
AAGCAGGGGGACTGGGTGTCGATCATGATCCCTAATGCCGACGCCGACCATCAGCTGCTGCAGCCAAAACGCGTCAGGCT
GCATGTGACCGGAATTTTACAGCTGAGCGGCCAGCTCGATCATAGTTTTGCCATGATCCCGATGCAGGATGCGCAGCAGT
ATCTGGAGATGGGCGGCAGCGTGACCGGCATCGCCATCAAGGTCACCGACGTTTTCCATGCTAACAAGCTGGTACGCGAC
GCCGGCGAGGTGACCAACAGCTACGTCTACATCAAGAGCTGGATCGGCACCTATGGCTATATGTATCGCGACATCCAGAT
GATCCGCGCCATTATGTACCTGGCGATGGTGCTGGTGATCGGCGTGGCCTGCTTTAACATCGTCTCGACGCTGGTGATGG
CGGTCAAAGACAAAAGCGGCGATATTGCGGTGCTGCGCACGCTTGGCGCAAAAGACGGCTTAATTCGCGCGATTTTCGTG
TGGTATGGTTTATTAGCCGGATCGGTAGGCAGCCTGTTTGGGGTGGTGATCGGCGTGATCTGCGCGTTGAACCTGACGTC
GATCATCAACGGCATCGAATACCTGATTGGGCATAAATTCCTCTCCGGCGACATCTATTTTATTGACTTCCTGCCGTCAG
AATTGCACTGGCTGGACGTCTTTTATGTGCTGGTGACAGCACTGTTGCTGAGTTTGCTGGCCAGCTGGTATCCCGCCCGC
CGCGCCAGCCGCATCGACCCGGCGAGGGTGCTGAGTGGCCAGTAA

Upstream 100 bases:

>100_bases
TGGTGACCCACGACCTGCAGCTGGCGAAGCGCATGAGCCGCCAGCTGGAGATGCGCGATGGCCGTCTGACCGCCGACCTG
ACCCTGATGGGGGCCGAGTA

Downstream 100 bases:

>100_bases
TTTATCGTCATCGTCGGCCTGGCTGACGACACAAGAGGAATTGCTGAAATGTATTATGGATTTGACATTGGCGGCAGCAA
GATAGCGCTGGGCGTATTTA

Product: outer membrane-specific lipoprotein transporter subunit LolE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MASPLSLLIALRFSRGRRRGGMVSLISVISTIGIALGVAVLIVGLSAMNGFERELNNRVLAVVPHGEIEPVNQPWNNWQE
ALAKVQKVKGIVAAAPYINFTGLVESGSNMRAIQVKGVDPQQESQLSALPTFVQNNAWAGFKAGEQQVILGKGVADALHV
KQGDWVSIMIPNADADHQLLQPKRVRLHVTGILQLSGQLDHSFAMIPMQDAQQYLEMGGSVTGIAIKVTDVFHANKLVRD
AGEVTNSYVYIKSWIGTYGYMYRDIQMIRAIMYLAMVLVIGVACFNIVSTLVMAVKDKSGDIAVLRTLGAKDGLIRAIFV
WYGLLAGSVGSLFGVVIGVICALNLTSIINGIEYLIGHKFLSGDIYFIDFLPSELHWLDVFYVLVTALLLSLLASWYPAR
RASRIDPARVLSGQ

Sequences:

>Translated_414_residues
MASPLSLLIALRFSRGRRRGGMVSLISVISTIGIALGVAVLIVGLSAMNGFERELNNRVLAVVPHGEIEPVNQPWNNWQE
ALAKVQKVKGIVAAAPYINFTGLVESGSNMRAIQVKGVDPQQESQLSALPTFVQNNAWAGFKAGEQQVILGKGVADALHV
KQGDWVSIMIPNADADHQLLQPKRVRLHVTGILQLSGQLDHSFAMIPMQDAQQYLEMGGSVTGIAIKVTDVFHANKLVRD
AGEVTNSYVYIKSWIGTYGYMYRDIQMIRAIMYLAMVLVIGVACFNIVSTLVMAVKDKSGDIAVLRTLGAKDGLIRAIFV
WYGLLAGSVGSLFGVVIGVICALNLTSIINGIEYLIGHKFLSGDIYFIDFLPSELHWLDVFYVLVTALLLSLLASWYPAR
RASRIDPARVLSGQ
>Mature_413_residues
ASPLSLLIALRFSRGRRRGGMVSLISVISTIGIALGVAVLIVGLSAMNGFERELNNRVLAVVPHGEIEPVNQPWNNWQEA
LAKVQKVKGIVAAAPYINFTGLVESGSNMRAIQVKGVDPQQESQLSALPTFVQNNAWAGFKAGEQQVILGKGVADALHVK
QGDWVSIMIPNADADHQLLQPKRVRLHVTGILQLSGQLDHSFAMIPMQDAQQYLEMGGSVTGIAIKVTDVFHANKLVRDA
GEVTNSYVYIKSWIGTYGYMYRDIQMIRAIMYLAMVLVIGVACFNIVSTLVMAVKDKSGDIAVLRTLGAKDGLIRAIFVW
YGLLAGSVGSLFGVVIGVICALNLTSIINGIEYLIGHKFLSGDIYFIDFLPSELHWLDVFYVLVTALLLSLLASWYPARR
ASRIDPARVLSGQ

Specific function: Part of an ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprote

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=414, Percent_Identity=87.1980676328502, Blast_Score=690, Evalue=0.0,
Organism=Escherichia coli, GI1787360, Length=420, Percent_Identity=27.3809523809524, Blast_Score=145, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925
- InterPro:   IPR011926 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45092; Mature: 44960

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS00027 HOMEOBOX_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASPLSLLIALRFSRGRRRGGMVSLISVISTIGIALGVAVLIVGLSAMNGFERELNNRVL
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCEE
AVVPHGEIEPVNQPWNNWQEALAKVQKVKGIVAAAPYINFTGLVESGSNMRAIQVKGVDP
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCEEEEEEECCCCEEEEEEECCCC
QQESQLSALPTFVQNNAWAGFKAGEQQVILGKGVADALHVKQGDWVSIMIPNADADHQLL
CHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCEEEEEECCCCCCCHHC
QPKRVRLHVTGILQLSGQLDHSFAMIPMQDAQQYLEMGGSVTGIAIKVTDVFHANKLVRD
CCCEEEEEEEEEEEECCCCCCCEEEEEHHHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHH
AGEVTNSYVYIKSWIGTYGYMYRDIQMIRAIMYLAMVLVIGVACFNIVSTLVMAVKDKSG
HHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DIAVLRTLGAKDGLIRAIFVWYGLLAGSVGSLFGVVIGVICALNLTSIINGIEYLIGHKF
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
LSGDIYFIDFLPSELHWLDVFYVLVTALLLSLLASWYPARRASRIDPARVLSGQ
ECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHCCCC
>Mature Secondary Structure 
ASPLSLLIALRFSRGRRRGGMVSLISVISTIGIALGVAVLIVGLSAMNGFERELNNRVL
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCEE
AVVPHGEIEPVNQPWNNWQEALAKVQKVKGIVAAAPYINFTGLVESGSNMRAIQVKGVDP
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCEEEEEEECCCCEEEEEEECCCC
QQESQLSALPTFVQNNAWAGFKAGEQQVILGKGVADALHVKQGDWVSIMIPNADADHQLL
CHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHCCCCCEEEEEECCCCCCCHHC
QPKRVRLHVTGILQLSGQLDHSFAMIPMQDAQQYLEMGGSVTGIAIKVTDVFHANKLVRD
CCCEEEEEEEEEEEECCCCCCCEEEEEHHHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHH
AGEVTNSYVYIKSWIGTYGYMYRDIQMIRAIMYLAMVLVIGVACFNIVSTLVMAVKDKSG
HHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DIAVLRTLGAKDGLIRAIFVWYGLLAGSVGSLFGVVIGVICALNLTSIINGIEYLIGHKF
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
LSGDIYFIDFLPSELHWLDVFYVLVTALLLSLLASWYPARRASRIDPARVLSGQ
ECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10783239 [H]