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The map label for this gene is cyaD [H]

Identifier: 152969554

GI number: 152969554

Start: 1145268

End: 1146488

Strand: Direct

Name: cyaD [H]

Synonym: KPN_00997

Alternate gene names: 152969554

Gene position: 1145268-1146488 (Clockwise)

Preceding gene: 152969553

Following gene: 152969555

Centisome position: 21.55

GC content: 51.84

Gene sequence:

>1221_bases
ATGAATAAGCCCACTGCTGCGATTTTCCCGTTGGTAAAGGAACTCGATCCGGTTGCTGCGATGGCTGATAACGAGCGTGA
TGAGGCCGAGCTGGTTAAATCGCGCCGCCTAATCGCTTTACTGGCGCTACTGCTGGTGGTCACAGGCGTTTGGGCGTGGT
TTGCCACGCTTGATGAAGTATCCACCGGGACCGGAAAAGTGATCCCCAGCTCGCGCGAACAGGTGTTGCAAACGCTCGAT
GGCGGGATCTTAACTGAGCTGAACGTTCGCGAAGGCAGCCGTGTCGCCGCGGGCCAGGTGGTCGCACGATTGGATCCGAC
CCGCAGTGAATCCAATGTTGGCGAAAGTCAGGCAAAATATCGCGCGTCATTAGCCGCAAGCATTCGCCTGACCGCCGAGG
TGAACAACCAACCGCTGATTTTTCCACCATCGCTGAAGGCCTGGCCGGGGCTACTGGCGGAAGAAACTCGCCTCTATCAC
AGTCGCAGGGAGCAGCTAACGAAGTCTATGCGGCAACTGGAGCAGTCGTTATCGCTGGTCAATAGTGAGCTGGCGATAAA
TGAAAAGCTGGCTAAGACCGGTGCGGCCAGTAATGTTGAAGTGCTTCGTTTACGCCAGCAGGCTGCCGATATTGAGCTAA
AGAAAATTGACCTCAACACTCGCTACTATGTTGATGCCCGCGAGCAGTTGTCAAAAGCCAATGCGGATGTCGCCAGCCTT
GCCGAAGTGATTAAGGGCCGGGCAGATTCAGTGGCTCGATTGACCGTGCGCTCACCGGTGCAGGGGATCGTCAAAAATAT
CAAAGTGAATACCATCGGCGGGGTTATCGCGCCTAACGGTGAACTGATGGATATCGTCCCCATTGATGGTCGATTGTTGA
TCGAAGCGCGGATTTCTCCGCGCGATATTGCATTTATTCATCCCGATCAGAAGGCGCTGGTGAAAATTACCGCCTATGAT
TATGCCATCTATGGCGCCCTCAATGGTGTTGTCGAAACGATATCTCCCGACACGATTCAGGACGAGGCAAAACCTGATGT
TTACTATTATCGGGTGTTTATCCGTACCGATCATAACTATCTGGAAAATAAACGCGGTAAGCGTTTTTTAATAGGTCCAG
GGATGATCGCTACGGTTGATATTAAAACCGGAGAGAAGACAGTTATGGATTATTTGGTGAAACCATTTAATAGGGCAAAA
GAAGCGCTGAGAGAAAGGTAA

Upstream 100 bases:

>100_bases
TCGATCGTATACTGGTTATTCAGGACGGGCAGCTGGCGCTGGATAAGCCTAAAGCGACGGTATTTGAGCAAGAAAAAGCG
CGTGCTCAGGTGGTGAACAT

Downstream 100 bases:

>100_bases
CACCTGCTAGTTAGCTTTATGTTTGGTGAATTTTCAACGAATGGAGATTTGAGATGGCATTGAGCGATTTATTACAACAG
GCTTGCTTTCAGTGCAAACC

Product: putative secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MNKPTAAIFPLVKELDPVAAMADNERDEAELVKSRRLIALLALLLVVTGVWAWFATLDEVSTGTGKVIPSSREQVLQTLD
GGILTELNVREGSRVAAGQVVARLDPTRSESNVGESQAKYRASLAASIRLTAEVNNQPLIFPPSLKAWPGLLAEETRLYH
SRREQLTKSMRQLEQSLSLVNSELAINEKLAKTGAASNVEVLRLRQQAADIELKKIDLNTRYYVDAREQLSKANADVASL
AEVIKGRADSVARLTVRSPVQGIVKNIKVNTIGGVIAPNGELMDIVPIDGRLLIEARISPRDIAFIHPDQKALVKITAYD
YAIYGALNGVVETISPDTIQDEAKPDVYYYRVFIRTDHNYLENKRGKRFLIGPGMIATVDIKTGEKTVMDYLVKPFNRAK
EALRER

Sequences:

>Translated_406_residues
MNKPTAAIFPLVKELDPVAAMADNERDEAELVKSRRLIALLALLLVVTGVWAWFATLDEVSTGTGKVIPSSREQVLQTLD
GGILTELNVREGSRVAAGQVVARLDPTRSESNVGESQAKYRASLAASIRLTAEVNNQPLIFPPSLKAWPGLLAEETRLYH
SRREQLTKSMRQLEQSLSLVNSELAINEKLAKTGAASNVEVLRLRQQAADIELKKIDLNTRYYVDAREQLSKANADVASL
AEVIKGRADSVARLTVRSPVQGIVKNIKVNTIGGVIAPNGELMDIVPIDGRLLIEARISPRDIAFIHPDQKALVKITAYD
YAIYGALNGVVETISPDTIQDEAKPDVYYYRVFIRTDHNYLENKRGKRFLIGPGMIATVDIKTGEKTVMDYLVKPFNRAK
EALRER
>Mature_406_residues
MNKPTAAIFPLVKELDPVAAMADNERDEAELVKSRRLIALLALLLVVTGVWAWFATLDEVSTGTGKVIPSSREQVLQTLD
GGILTELNVREGSRVAAGQVVARLDPTRSESNVGESQAKYRASLAASIRLTAEVNNQPLIFPPSLKAWPGLLAEETRLYH
SRREQLTKSMRQLEQSLSLVNSELAINEKLAKTGAASNVEVLRLRQQAADIELKKIDLNTRYYVDAREQLSKANADVASL
AEVIKGRADSVARLTVRSPVQGIVKNIKVNTIGGVIAPNGELMDIVPIDGRLLIEARISPRDIAFIHPDQKALVKITAYD
YAIYGALNGVVETISPDTIQDEAKPDVYYYRVFIRTDHNYLENKRGKRFLIGPGMIATVDIKTGEKTVMDYLVKPFNRAK
EALRER

Specific function: CyaD is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 44880; Mature: 44880

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPTAAIFPLVKELDPVAAMADNERDEAELVKSRRLIALLALLLVVTGVWAWFATLDEV
CCCCHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
STGTGKVIPSSREQVLQTLDGGILTELNVREGSRVAAGQVVARLDPTRSESNVGESQAKY
CCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHEECCCCCCCCCCCHHHHHH
RASLAASIRLTAEVNNQPLIFPPSLKAWPGLLAEETRLYHSRREQLTKSMRQLEQSLSLV
HHHHHEEEEEEEEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSELAINEKLAKTGAASNVEVLRLRQQAADIELKKIDLNTRYYVDAREQLSKANADVASL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEECCCEEEECHHHHHHHCCCCHHHH
AEVIKGRADSVARLTVRSPVQGIVKNIKVNTIGGVIAPNGELMDIVPIDGRLLIEARISP
HHHHCCCCCCEEEEEHHHHHHHHHHHCEEEECCCEECCCCCEEEEEECCCEEEEEEECCC
RDIAFIHPDQKALVKITAYDYAIYGALNGVVETISPDTIQDEAKPDVYYYRVFIRTDHNY
CEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCHH
LENKRGKRFLIGPGMIATVDIKTGEKTVMDYLVKPFNRAKEALRER
HHCCCCCEEEECCCEEEEEEECCCHHHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure
MNKPTAAIFPLVKELDPVAAMADNERDEAELVKSRRLIALLALLLVVTGVWAWFATLDEV
CCCCHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
STGTGKVIPSSREQVLQTLDGGILTELNVREGSRVAAGQVVARLDPTRSESNVGESQAKY
CCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHEECCCCCCCCCCCHHHHHH
RASLAASIRLTAEVNNQPLIFPPSLKAWPGLLAEETRLYHSRREQLTKSMRQLEQSLSLV
HHHHHEEEEEEEEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSELAINEKLAKTGAASNVEVLRLRQQAADIELKKIDLNTRYYVDAREQLSKANADVASL
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEEECCCEEEECHHHHHHHCCCCHHHH
AEVIKGRADSVARLTVRSPVQGIVKNIKVNTIGGVIAPNGELMDIVPIDGRLLIEARISP
HHHHCCCCCCEEEEEHHHHHHHHHHHCEEEECCCEECCCCCEEEEEECCCEEEEEEECCC
RDIAFIHPDQKALVKITAYDYAIYGALNGVVETISPDTIQDEAKPDVYYYRVFIRTDHNY
CEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCHH
LENKRGKRFLIGPGMIATVDIKTGEKTVMDYLVKPFNRAKEALRER
HHCCCCCEEEECCCEEEEEEECCCHHHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2905265; 12910271 [H]