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The map label for this gene is murA

Identifier: 151222216

GI number: 151222216

Start: 2222927

End: 2224192

Strand: Reverse

Name: murA

Synonym: NWMN_2004

Alternate gene names: 151222216

Gene position: 2224192-2222927 (Counterclockwise)

Preceding gene: 151222217

Following gene: 151222215

Centisome position: 77.26

GC content: 36.18

Gene sequence:

>1266_bases
ATGGATAAAATAGTAATCAAAGGTGGAAATAAATTAACGGGTGAAGTTAAAGTAGAAGGTGCTAAAAATGCAGTATTACC
AATATTGACAGCATCTTTATTAGCTTCTGATAAACCGAGCAAATTAGTTAATGTTCCAGCTTTAAGTGATGTAGAAACAA
TAAATAATGTATTAACAACTTTAAATGCTGACGTTACATACAAAAAGGACGAAAATGCTGTTGTCGTTGATGCAACAAAG
ACTCTAAATGAAGAGGCACCATATGAATATGTTAGTAAAATGCGTGCAAGTATTTTAGTTATGGGACCTCTTTTAGCAAG
ACTAGGACATGCTATTGTTGCATTGCCTGGTGGTTGTGCAATTGGAAGTAGACCGATTGAGCAACACATTAAAGGTTTTG
AAGCTTTAGGCGCAGAAATTCATCTTGAAAATGGTAATATTTATGCTAATGCTAAAGATGGATTAAAAGGTACATCAATT
CATTTAGATTTTCCAAGTGTAGGAGCAACACAAAATATTATTATGGCAGCATCATTAGCTAAGGGTAAGACTTTAATTGA
AAATGCAGCTAAAGAACCTGAAATTGTCGATTTAGCAAACTACATTAATGAAATGGGTGGTAGAATTACTGGTGCTGGTA
CAGACACAATTACAATCAATGGTGTAGAATCATTACATGGTGTAGAACATGCTATCATTCCAGATAGAATTGAAGCAGGC
ACATTACTAATCGCTGGTGCTATAACGCGTGGTGATATTTTTGTACGTGGTGCAATCAAAGAACATATGGCGAGTTTAGT
CTATAAACTAGAAGAAATGGGCGTTGAATTGGACTATCAAGAAGATGGTATTCGTGTACGTGCTGAAGGGGAATTACAAC
CTGTAGACATCAAAACTCTACCACATCCTGGATTCCCGACTGATATGCAATCACAAATGATGGCATTGTTATTAACGGCA
AATGGTCATAAAGTCGTAACCGAAACTGTTTTTGAAAACCGTTTTATGCATGTTGCAGAGTTCAAACGTATGAATGCTAA
TATCAATGTAGAAGGTCGTAGTGCTAAACTTGAAGGTAAAAGTCAATTGCAAGGTGCACAAGTTAAAGCGACTGATTTAA
GAGCAGCAGCCGCCTTAATTTTAGCTGGATTAGTTGCTGATGGTAAAACAAGCGTTACTGAATTAACGCACCTAGATAGA
GGCTATGTTGACTTACACGGTAAATTGAAGCAATTAGGTGCAGACATTGAACGTATTAACGATTAA

Upstream 100 bases:

>100_bases
ATGATTTGTAATCAAAACTAGATATAATTAAATAATGACTTAAAATAATTTTAAAATAGGGAAATGTAAAGTAATAGGAG
TTCTAAGTGGAGGATTTACG

Downstream 100 bases:

>100_bases
TTCAGTAAATTAATATAATGGAGGATTTCAACCATGGAAACAATTTTTGATTATAACCAAATTAAACAAATTATACCTCA
CAGACAGCCATTTTTATTAA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 1; UDP-N-acetylglucosamine enolpyruvyl transferase 1; EPT 1 [H]

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MDKIVIKGGNKLTGEVKVEGAKNAVLPILTASLLASDKPSKLVNVPALSDVETINNVLTTLNADVTYKKDENAVVVDATK
TLNEEAPYEYVSKMRASILVMGPLLARLGHAIVALPGGCAIGSRPIEQHIKGFEALGAEIHLENGNIYANAKDGLKGTSI
HLDFPSVGATQNIIMAASLAKGKTLIENAAKEPEIVDLANYINEMGGRITGAGTDTITINGVESLHGVEHAIIPDRIEAG
TLLIAGAITRGDIFVRGAIKEHMASLVYKLEEMGVELDYQEDGIRVRAEGELQPVDIKTLPHPGFPTDMQSQMMALLLTA
NGHKVVTETVFENRFMHVAEFKRMNANINVEGRSAKLEGKSQLQGAQVKATDLRAAAALILAGLVADGKTSVTELTHLDR
GYVDLHGKLKQLGADIERIND

Sequences:

>Translated_421_residues
MDKIVIKGGNKLTGEVKVEGAKNAVLPILTASLLASDKPSKLVNVPALSDVETINNVLTTLNADVTYKKDENAVVVDATK
TLNEEAPYEYVSKMRASILVMGPLLARLGHAIVALPGGCAIGSRPIEQHIKGFEALGAEIHLENGNIYANAKDGLKGTSI
HLDFPSVGATQNIIMAASLAKGKTLIENAAKEPEIVDLANYINEMGGRITGAGTDTITINGVESLHGVEHAIIPDRIEAG
TLLIAGAITRGDIFVRGAIKEHMASLVYKLEEMGVELDYQEDGIRVRAEGELQPVDIKTLPHPGFPTDMQSQMMALLLTA
NGHKVVTETVFENRFMHVAEFKRMNANINVEGRSAKLEGKSQLQGAQVKATDLRAAAALILAGLVADGKTSVTELTHLDR
GYVDLHGKLKQLGADIERIND
>Mature_421_residues
MDKIVIKGGNKLTGEVKVEGAKNAVLPILTASLLASDKPSKLVNVPALSDVETINNVLTTLNADVTYKKDENAVVVDATK
TLNEEAPYEYVSKMRASILVMGPLLARLGHAIVALPGGCAIGSRPIEQHIKGFEALGAEIHLENGNIYANAKDGLKGTSI
HLDFPSVGATQNIIMAASLAKGKTLIENAAKEPEIVDLANYINEMGGRITGAGTDTITINGVESLHGVEHAIIPDRIEAG
TLLIAGAITRGDIFVRGAIKEHMASLVYKLEEMGVELDYQEDGIRVRAEGELQPVDIKTLPHPGFPTDMQSQMMALLLTA
NGHKVVTETVFENRFMHVAEFKRMNANINVEGRSAKLEGKSQLQGAQVKATDLRAAAALILAGLVADGKTSVTELTHLDR
GYVDLHGKLKQLGADIERIND

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=421, Percent_Identity=49.1686460807601, Blast_Score=392, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44996; Mature: 44996

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIVIKGGNKLTGEVKVEGAKNAVLPILTASLLASDKPSKLVNVPALSDVETINNVLTT
CCEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHH
LNADVTYKKDENAVVVDATKTLNEEAPYEYVSKMRASILVMGPLLARLGHAIVALPGGCA
CCCCEEEECCCCEEEEECHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCC
IGSRPIEQHIKGFEALGAEIHLENGNIYANAKDGLKGTSIHLDFPSVGATQNIIMAASLA
CCCCCHHHHHHHHHHCCCEEEEECCCEEEECCCCCCCCEEEEECCCCCCCCCEEEEEHHH
KGKTLIENAAKEPEIVDLANYINEMGGRITGAGTDTITINGVESLHGVEHAIIPDRIEAG
CCHHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEECCHHHHCCCCCCCCCCCCCCC
TLLIAGAITRGDIFVRGAIKEHMASLVYKLEEMGVELDYQEDGIRVRAEGELQPVDIKTL
EEEEEEEEECCCEEEEHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCEEEEEEC
PHPGFPTDMQSQMMALLLTANGHKVVTETVFENRFMHVAEFKRMNANINVEGRSAKLEGK
CCCCCCCCHHHHHEEEEEECCCCEEEHHHHHHHCCHHHHHHHHCCCCEEECCCCEECCCH
SQLQGAQVKATDLRAAAALILAGLVADGKTSVTELTHLDRGYVDLHGKLKQLGADIERIN
HHCCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEHHHHHHHHCCHHHHCC
D
C
>Mature Secondary Structure
MDKIVIKGGNKLTGEVKVEGAKNAVLPILTASLLASDKPSKLVNVPALSDVETINNVLTT
CCEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHH
LNADVTYKKDENAVVVDATKTLNEEAPYEYVSKMRASILVMGPLLARLGHAIVALPGGCA
CCCCEEEECCCCEEEEECHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCC
IGSRPIEQHIKGFEALGAEIHLENGNIYANAKDGLKGTSIHLDFPSVGATQNIIMAASLA
CCCCCHHHHHHHHHHCCCEEEEECCCEEEECCCCCCCCEEEEECCCCCCCCCEEEEEHHH
KGKTLIENAAKEPEIVDLANYINEMGGRITGAGTDTITINGVESLHGVEHAIIPDRIEAG
CCHHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEECCHHHHCCCCCCCCCCCCCCC
TLLIAGAITRGDIFVRGAIKEHMASLVYKLEEMGVELDYQEDGIRVRAEGELQPVDIKTL
EEEEEEEEECCCEEEEHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCEEEEEEC
PHPGFPTDMQSQMMALLLTANGHKVVTETVFENRFMHVAEFKRMNANINVEGRSAKLEGK
CCCCCCCCHHHHHEEEEEECCCCEEEHHHHHHHCCHHHHHHHHCCCCEEECCCCEECCCH
SQLQGAQVKATDLRAAAALILAGLVADGKTSVTELTHLDRGYVDLHGKLKQLGADIERIN
HHCCCCEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEHHHHHHHHCCHHHHCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA