Definition Methanococcus aeolicus Nankai-3, complete genome.
Accession NC_009635
Length 1,569,500

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The map label for this gene is mtrH

Identifier: 150401698

GI number: 150401698

Start: 1337825

End: 1338784

Strand: Direct

Name: mtrH

Synonym: Maeo_1276

Alternate gene names: 150401698

Gene position: 1337825-1338784 (Clockwise)

Preceding gene: 150401697

Following gene: 150401703

Centisome position: 85.24

GC content: 38.96

Gene sequence:

>960_bases
ATGTTCAAATTTGATAAAGAACAGATGGTTATTGAAATCGCAGGTAGAAAATTCGGCGGTCAGCCGGGAGAATACCCAAC
AGGTCTATCTGGAACAATATTTTATGCAAGACACAAAATTGTAGAAGATGAAATAAAAGGGATTTTCGATAAATCCGCAG
CAGAAGCATTAATAAACAAACAAGCTGAAATGGAAGACACCACAGGAAACCCTGCATTAGTTCAGGTATTTGGTGGAAAC
CCAGAGGCATTAACAAAATATATCGACTTCGTAGCTGAAGTATGGGATGGTCCAATGTTATTGGACTCCACATCAGGAGA
AGCTAGAATGGCAGCCGCTACAAGGGCAACCGAAGCAGGATATGCAAATCAATGTATTTACAACTCTATCAATGTTTCAA
TAGATGAGGCAGAATTCCAAAACTTGGTAGAAAGTGATATAGAAGCTTCCATTGTGTTGTGTTTCGACCCAATGGACCCA
TCAGTTGAAGGTAAATTAAATGTGTTGTTAGATGGTGGAAAAACAACAGATACAGGTATGCTTGATTTAGCTGAAAAAGC
GGGAATTAAATACCCATTAATTGATGTTGCATGTACTCCATTAGGAAGTGGTGCAGGTCAGTCTGTAAGGGCATCATTCG
CTGTTAAAGCAAAATTAGGTCTTCCAGTAGGTAGTGGTATCCACAACATCCCATCAGCATGGGACTGGTTAAGAGATTTC
AGAAAAGGATTAAGAGAAGCAGGACAAACCCAATTAGCAAAAGATGTTCATCATGTTTGTGATATTGGAGCTAATATTGT
TCAAACAATGGGTTCCGGAGACTTTGTTTTATACGGACCTATTGACAATGCAGAATTAGCATTCCCAGCAGTTGCTATGA
CCGATATGGTTATTGCAGAAACAGCAAAAGATATGGGAACAGTTCCAGTAGATACCCATCCAATAAACAAATTGTTATAA

Upstream 100 bases:

>100_bases
GCAATAGGATTAGTATTTGTAATGGTAGTTGGAAAATTATTGCCAATATTTAGTAAATTCCTATAAAAAAATAAGGATAT
ATATTATAAGGTGGTAATTG

Downstream 100 bases:

>100_bases
TGTGGTTGAAAAATAAATAAAATATATATTTTCTTTTTTATTATTTTTTAGGGTTTTTTATTCTAAAAATAGATTTTAAT
ATTAAATTGCTATTTTGTAA

Product: tetrahydromethanopterin S-methyltransferase subunit H

Products: NA

Alternate protein names: N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit H

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MFKFDKEQMVIEIAGRKFGGQPGEYPTGLSGTIFYARHKIVEDEIKGIFDKSAAEALINKQAEMEDTTGNPALVQVFGGN
PEALTKYIDFVAEVWDGPMLLDSTSGEARMAAATRATEAGYANQCIYNSINVSIDEAEFQNLVESDIEASIVLCFDPMDP
SVEGKLNVLLDGGKTTDTGMLDLAEKAGIKYPLIDVACTPLGSGAGQSVRASFAVKAKLGLPVGSGIHNIPSAWDWLRDF
RKGLREAGQTQLAKDVHHVCDIGANIVQTMGSGDFVLYGPIDNAELAFPAVAMTDMVIAETAKDMGTVPVDTHPINKLL

Sequences:

>Translated_319_residues
MFKFDKEQMVIEIAGRKFGGQPGEYPTGLSGTIFYARHKIVEDEIKGIFDKSAAEALINKQAEMEDTTGNPALVQVFGGN
PEALTKYIDFVAEVWDGPMLLDSTSGEARMAAATRATEAGYANQCIYNSINVSIDEAEFQNLVESDIEASIVLCFDPMDP
SVEGKLNVLLDGGKTTDTGMLDLAEKAGIKYPLIDVACTPLGSGAGQSVRASFAVKAKLGLPVGSGIHNIPSAWDWLRDF
RKGLREAGQTQLAKDVHHVCDIGANIVQTMGSGDFVLYGPIDNAELAFPAVAMTDMVIAETAKDMGTVPVDTHPINKLL
>Mature_319_residues
MFKFDKEQMVIEIAGRKFGGQPGEYPTGLSGTIFYARHKIVEDEIKGIFDKSAAEALINKQAEMEDTTGNPALVQVFGGN
PEALTKYIDFVAEVWDGPMLLDSTSGEARMAAATRATEAGYANQCIYNSINVSIDEAEFQNLVESDIEASIVLCFDPMDP
SVEGKLNVLLDGGKTTDTGMLDLAEKAGIKYPLIDVACTPLGSGAGQSVRASFAVKAKLGLPVGSGIHNIPSAWDWLRDF
RKGLREAGQTQLAKDVHHVCDIGANIVQTMGSGDFVLYGPIDNAELAFPAVAMTDMVIAETAKDMGTVPVDTHPINKLL

Specific function: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl grou

COG id: COG1962

COG function: function code H; Tetrahydromethanopterin S-methyltransferase, subunit H

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mtrH family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTRH_META3 (A6UWI0)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001325464.1
- STRING:   A6UWI0
- GeneID:   5326934
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_1276
- eggNOG:   arNOG04816
- HOGENOM:   HBG512918
- OMA:   YARHKIV
- ProtClustDB:   PRK00979
- BioCyc:   MAEO419665:MAEO_1276-MONOMER
- GO:   GO:0015948
- HAMAP:   MF_01501
- InterPro:   IPR011005
- InterPro:   IPR002856
- ProDom:   PD009948
- TIGRFAMs:   TIGR01114

Pfam domain/function: PF02007 MtrH; SSF51717 DHP_synth_like

EC number: =2.1.1.86

Molecular weight: Translated: 34179; Mature: 34179

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKFDKEQMVIEIAGRKFGGQPGEYPTGLSGTIFYARHKIVEDEIKGIFDKSAAEALINK
CCCCCCHHEEEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
QAEMEDTTGNPALVQVFGGNPEALTKYIDFVAEVWDGPMLLDSTSGEARMAAATRATEAG
HHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCC
YANQCIYNSINVSIDEAEFQNLVESDIEASIVLCFDPMDPSVEGKLNVLLDGGKTTDTGM
CCCHHEECCCCEEECHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEEEEECCCCCCCHH
LDLAEKAGIKYPLIDVACTPLGSGAGQSVRASFAVKAKLGLPVGSGIHNIPSAWDWLRDF
HHHHHHCCCCCCCCEEEECCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHH
RKGLREAGQTQLAKDVHHVCDIGANIVQTMGSGDFVLYGPIDNAELAFPAVAMTDMVIAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHH
TAKDMGTVPVDTHPINKLL
HHHHCCCCCCCCCCHHHCC
>Mature Secondary Structure
MFKFDKEQMVIEIAGRKFGGQPGEYPTGLSGTIFYARHKIVEDEIKGIFDKSAAEALINK
CCCCCCHHEEEEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
QAEMEDTTGNPALVQVFGGNPEALTKYIDFVAEVWDGPMLLDSTSGEARMAAATRATEAG
HHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCC
YANQCIYNSINVSIDEAEFQNLVESDIEASIVLCFDPMDPSVEGKLNVLLDGGKTTDTGM
CCCHHEECCCCEEECHHHHHHHHHCCCCEEEEEEECCCCCCCCCEEEEEEECCCCCCCHH
LDLAEKAGIKYPLIDVACTPLGSGAGQSVRASFAVKAKLGLPVGSGIHNIPSAWDWLRDF
HHHHHHCCCCCCCCEEEECCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHH
RKGLREAGQTQLAKDVHHVCDIGANIVQTMGSGDFVLYGPIDNAELAFPAVAMTDMVIAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHH
TAKDMGTVPVDTHPINKLL
HHHHCCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA