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The map label for this gene is mtrA

Identifier: 150401695

GI number: 150401695

Start: 1336030

End: 1336752

Strand: Direct

Name: mtrA

Synonym: Maeo_1273

Alternate gene names: 150401695

Gene position: 1336030-1336752 (Clockwise)

Preceding gene: 150401694

Following gene: 150401696

Centisome position: 85.12

GC content: 36.65

Gene sequence:

>723_bases
ATGGCAGATAAAAAAGCTCCTGCATCAGGATGGCCAATAGTAAGTGGCGAATATGTTGTAGGAAACCCAGAAAGCTGTGT
AGCAGTTGTAACATTGGGTTCCCATGGTTTAGATGAAGCAGCTATTGAAGCAGGTGCTGCTATTTCAGGACCATGCCACA
CAGAAAATTTAGGGATTGAAAAAGTTGTAGCTAATTATATATCAAATCCAAACATTAGGTTTATGTTGGTTACTGGTTCC
GAAGTTCAAGGACATATTACAGGACAGTGCTTTAAAGCATTGTATGAAAATGGAATTGGAGATGATGGAGGAATTATTGG
AGCAAAAGGAGCTATTCCATTTTTGGAAAATGCTGGACAAGATGCTATCAGTAGATTCCAAAATCAACTTGTGGAAATTG
TAGATTTGATTGATGTTGAAGATACAGGTAAAATAAGCAGTGCTATTAAAGACTGTATTTCAAAAGACCCTGGTGCTTTC
GAAGAAGATCCAATGATATTGGATTTAGAAGGCGGCGGTGGAGAAGCTGGAGCTGATGAATCTACATCAATAAAACCAGC
TGCGCCAGAAACAGTATTATTGGAAGCAAGAATGAGAATGATATCTGAAAAAATAAATGATGCAGCATTAATAGCAAAAT
TCAATTCAGGATATTATAATGGAAAAATACAAGGAATTGCAATAGGGTTGTTCCTATCTTTGTTAATATTCTCCTTGTTA
TAG

Upstream 100 bases:

>100_bases
TTGGTTTCTGGATATCTTTATCAATATTAACATTGGGATTAATACTTGTAATAGGTTTATATCCTAAATTAATAGGGTTA
TAATTTGGAGGTGCTAATAT

Downstream 100 bases:

>100_bases
ATATATATTGCAGATATGAATAATTTGGAGGTGCTAATATATGGCAGATAAAAAAGCTCCTGCATCAGGATGGCCAATAG
TAAGTGGCGAATATGTTGTA

Product: tetrahydromethanopterin S-methyltransferase subunit A

Products: NA

Alternate protein names: N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit A

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MADKKAPASGWPIVSGEYVVGNPESCVAVVTLGSHGLDEAAIEAGAAISGPCHTENLGIEKVVANYISNPNIRFMLVTGS
EVQGHITGQCFKALYENGIGDDGGIIGAKGAIPFLENAGQDAISRFQNQLVEIVDLIDVEDTGKISSAIKDCISKDPGAF
EEDPMILDLEGGGGEAGADESTSIKPAAPETVLLEARMRMISEKINDAALIAKFNSGYYNGKIQGIAIGLFLSLLIFSLL

Sequences:

>Translated_240_residues
MADKKAPASGWPIVSGEYVVGNPESCVAVVTLGSHGLDEAAIEAGAAISGPCHTENLGIEKVVANYISNPNIRFMLVTGS
EVQGHITGQCFKALYENGIGDDGGIIGAKGAIPFLENAGQDAISRFQNQLVEIVDLIDVEDTGKISSAIKDCISKDPGAF
EEDPMILDLEGGGGEAGADESTSIKPAAPETVLLEARMRMISEKINDAALIAKFNSGYYNGKIQGIAIGLFLSLLIFSLL
>Mature_239_residues
ADKKAPASGWPIVSGEYVVGNPESCVAVVTLGSHGLDEAAIEAGAAISGPCHTENLGIEKVVANYISNPNIRFMLVTGSE
VQGHITGQCFKALYENGIGDDGGIIGAKGAIPFLENAGQDAISRFQNQLVEIVDLIDVEDTGKISSAIKDCISKDPGAFE
EDPMILDLEGGGGEAGADESTSIKPAAPETVLLEARMRMISEKINDAALIAKFNSGYYNGKIQGIAIGLFLSLLIFSLL

Specific function: Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step

COG id: COG4063

COG function: function code H; Tetrahydromethanopterin S-methyltransferase, subunit A

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MtrA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTRA_META3 (A6UWH7)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001325461.1
- STRING:   A6UWH7
- GeneID:   5327467
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_1273
- eggNOG:   arNOG07825
- HOGENOM:   HBG542039
- OMA:   EPVERLQ
- ProtClustDB:   PRK00964
- BioCyc:   MAEO419665:MAEO_1273-MONOMER
- GO:   GO:0005737
- GO:   GO:0015948
- HAMAP:   MF_01093
- InterPro:   IPR005778
- InterPro:   IPR013340
- TIGRFAMs:   TIGR01111

Pfam domain/function: PF04208 MtrA

EC number: =2.1.1.86

Molecular weight: Translated: 25071; Mature: 24940

Theoretical pI: Translated: 4.16; Mature: 4.16

Prosite motif: NA

Important sites: BINDING 85-85

Signals:

None

Transmembrane regions:

HASH(0x1d7180a4)-;

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKKAPASGWPIVSGEYVVGNPESCVAVVTLGSHGLDEAAIEAGAAISGPCHTENLGIE
CCCCCCCCCCCCEECCCEEECCCCCEEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCHH
KVVANYISNPNIRFMLVTGSEVQGHITGQCFKALYENGIGDDGGIIGAKGAIPFLENAGQ
HHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHCCCH
DAISRFQNQLVEIVDLIDVEDTGKISSAIKDCISKDPGAFEEDPMILDLEGGGGEAGADE
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCC
STSIKPAAPETVLLEARMRMISEKINDAALIAKFNSGYYNGKIQGIAIGLFLSLLIFSLL
CCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCEECCEEHHHHHHHHHHHHHHHHH
>Mature Secondary Structure 
ADKKAPASGWPIVSGEYVVGNPESCVAVVTLGSHGLDEAAIEAGAAISGPCHTENLGIE
CCCCCCCCCCCEECCCEEECCCCCEEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCHH
KVVANYISNPNIRFMLVTGSEVQGHITGQCFKALYENGIGDDGGIIGAKGAIPFLENAGQ
HHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHCCCH
DAISRFQNQLVEIVDLIDVEDTGKISSAIKDCISKDPGAFEEDPMILDLEGGGGEAGADE
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCC
STSIKPAAPETVLLEARMRMISEKINDAALIAKFNSGYYNGKIQGIAIGLFLSLLIFSLL
CCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCEECCEEHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA