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The map label for this gene is mcrA [H]

Identifier: 150401690

GI number: 150401690

Start: 1331150

End: 1332808

Strand: Direct

Name: mcrA [H]

Synonym: Maeo_1268

Alternate gene names: 150401690

Gene position: 1331150-1332808 (Clockwise)

Preceding gene: 150401689

Following gene: 150401691

Centisome position: 84.81

GC content: 39.9

Gene sequence:

>1659_bases
ATGGAAGCTGAAAAGAAATTATTCTTAAAAGCATTGAAAGAAAAGTTTGATGAAGACCCAAAGGAAAAATATACAAAATT
CTACACCTACGGCGGATGGAAACAATCCAAAAGAAAAACAGAATTTGTTGAAGCAGCAAAGGATATCGCTGATAAAAGGG
GAGGAATGCCGGGGTACAACCCAGATATCGGTGTTCCGCTCGGACAAAGAAAAATGATGTCCTATAAATTATCAGGTACC
GACGACTATGTTGAAGGTGATGATTTACACTTTATGAACAATGCTGCTATTCAACAATTGCACGATGACATTAGAAGAAC
AGTTATTGTTGGTATGGATACTGGACACATGGTATTGGAGAAAAGGCTAGGTGTAGAAGTTACTCCTGAAACCATCAACG
AATATATGGAAACAATAAACCACGCTTTACCTGGTGGTGCTGTTGTTCAAGAACACATGGTGGAAGTAGACCCTGCATTA
GCATGGGATTCATATGCTAAAATCTTCACAGGAGACGATGAGTTAGCTGACGAACTCGATAAAAGAGTTTTAGTTGATAT
TAACAAATTGTTCCCAGAAGAACAAGCAGAAGAATTAAAAGCTGCTATCGGTAAAAAAACATACCAAATATCAAGAGTTC
CTACATTAGTTGGTAGAGTATGTGATGGGGGAACCATTGCAAGATGGTCTGCTATGCAGATAGGAATGTCCTTCATTACA
GCATACAAACTTTGTGCTGGGGAAGCTGCTATTGCTGATTTCTCATACGCAGCAAAACACGCTGATGTTATCGGAATGGG
TACAGCACTTCCAGCAAGAAGGTCAAGAGGAGCAAATGAGCCAGGGGGAATTCCATTTGGTATTTTGTGTGATGTTGTTC
AAACAACAAGAATCAGTGATGACCCAGTTGAGCAATCATTAGAGGTAGTTGCTACCGGAGCTATGTTATATGACCAAATC
TGGTTAGGTGCATACATGTCTGGTGGTGTAGGATTTACCCAATATGCAACAGCAGCATACACTGATGACATCTTAGATGA
TTTCTGCTACTATGGATTAGACTATGTAGAGAAAAAATTCGGTAGATGTGGAACAAAAGCTACAATGGATGTTGTAGAAG
ATATTGCAACAGAAGTTACACTTTATTCACTTGAACAATATGATGAATACCCAACATTATTGGAAGACCACTTTGGAGGT
TCCCAAAGAGCAGCAGTTGCAGCAGCAGCGGCTGGTGTTTCAGTATGTATGGCAACAGGAAACTCAAATGCAGGAGTTAA
TGGATGGTATTTGAGCCAAATAATGCATAAAGAATACCACAGTAGGTTAGGATTCTACGGATACGACTTACAAGACCAGT
GTGGAGCTTCAAACTCATTATCTATTAGAAATGACGAATCCTCACCATTGGAATTAAGAGGTCCAAACTATCCAAACTAT
GCAATGAATGTTGGTCACCAAGGAGAATATGCAGGTATCACCCAAGCAGCACACTCTGCAAGAGGAGATGCTTTTGCTAT
GAATCCATTAATTAAAGTTGCATTTGCTGACCCATCATTAATATTTGACTTCGCACGACCAAGAAAATGTTGTGCAAGAG
GAGCTCTCAGAGAGTTCGAAGTAGCAGGAGAAAGAGACCCAATCTTACCCGCAAAATAA

Upstream 100 bases:

>100_bases
CTACTGAAAAAATCTTCGAAGGATTGTAAGTGAAATACGATACAGCAAATATTGAATATATTACTTAACCTACCTCTACT
TACCTTTTGAGGTGAATTTT

Downstream 100 bases:

>100_bases
TATAATTTGGGCATATATTACATAGAACATAAAGGGAGCTCCCTTTTATTGTTCCCTTTTTTAAATATATCTATTTATTT
TTTTGTTCTGGATTTTGTTT

Product: coenzyme-B sulfoethylthiotransferase

Products: NA

Alternate protein names: Coenzyme-B sulfoethylthiotransferase alpha [H]

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MEAEKKLFLKALKEKFDEDPKEKYTKFYTYGGWKQSKRKTEFVEAAKDIADKRGGMPGYNPDIGVPLGQRKMMSYKLSGT
DDYVEGDDLHFMNNAAIQQLHDDIRRTVIVGMDTGHMVLEKRLGVEVTPETINEYMETINHALPGGAVVQEHMVEVDPAL
AWDSYAKIFTGDDELADELDKRVLVDINKLFPEEQAEELKAAIGKKTYQISRVPTLVGRVCDGGTIARWSAMQIGMSFIT
AYKLCAGEAAIADFSYAAKHADVIGMGTALPARRSRGANEPGGIPFGILCDVVQTTRISDDPVEQSLEVVATGAMLYDQI
WLGAYMSGGVGFTQYATAAYTDDILDDFCYYGLDYVEKKFGRCGTKATMDVVEDIATEVTLYSLEQYDEYPTLLEDHFGG
SQRAAVAAAAAGVSVCMATGNSNAGVNGWYLSQIMHKEYHSRLGFYGYDLQDQCGASNSLSIRNDESSPLELRGPNYPNY
AMNVGHQGEYAGITQAAHSARGDAFAMNPLIKVAFADPSLIFDFARPRKCCARGALREFEVAGERDPILPAK

Sequences:

>Translated_552_residues
MEAEKKLFLKALKEKFDEDPKEKYTKFYTYGGWKQSKRKTEFVEAAKDIADKRGGMPGYNPDIGVPLGQRKMMSYKLSGT
DDYVEGDDLHFMNNAAIQQLHDDIRRTVIVGMDTGHMVLEKRLGVEVTPETINEYMETINHALPGGAVVQEHMVEVDPAL
AWDSYAKIFTGDDELADELDKRVLVDINKLFPEEQAEELKAAIGKKTYQISRVPTLVGRVCDGGTIARWSAMQIGMSFIT
AYKLCAGEAAIADFSYAAKHADVIGMGTALPARRSRGANEPGGIPFGILCDVVQTTRISDDPVEQSLEVVATGAMLYDQI
WLGAYMSGGVGFTQYATAAYTDDILDDFCYYGLDYVEKKFGRCGTKATMDVVEDIATEVTLYSLEQYDEYPTLLEDHFGG
SQRAAVAAAAAGVSVCMATGNSNAGVNGWYLSQIMHKEYHSRLGFYGYDLQDQCGASNSLSIRNDESSPLELRGPNYPNY
AMNVGHQGEYAGITQAAHSARGDAFAMNPLIKVAFADPSLIFDFARPRKCCARGALREFEVAGERDPILPAK
>Mature_552_residues
MEAEKKLFLKALKEKFDEDPKEKYTKFYTYGGWKQSKRKTEFVEAAKDIADKRGGMPGYNPDIGVPLGQRKMMSYKLSGT
DDYVEGDDLHFMNNAAIQQLHDDIRRTVIVGMDTGHMVLEKRLGVEVTPETINEYMETINHALPGGAVVQEHMVEVDPAL
AWDSYAKIFTGDDELADELDKRVLVDINKLFPEEQAEELKAAIGKKTYQISRVPTLVGRVCDGGTIARWSAMQIGMSFIT
AYKLCAGEAAIADFSYAAKHADVIGMGTALPARRSRGANEPGGIPFGILCDVVQTTRISDDPVEQSLEVVATGAMLYDQI
WLGAYMSGGVGFTQYATAAYTDDILDDFCYYGLDYVEKKFGRCGTKATMDVVEDIATEVTLYSLEQYDEYPTLLEDHFGG
SQRAAVAAAAAGVSVCMATGNSNAGVNGWYLSQIMHKEYHSRLGFYGYDLQDQCGASNSLSIRNDESSPLELRGPNYPNY
AMNVGHQGEYAGITQAAHSARGDAFAMNPLIKVAFADPSLIFDFARPRKCCARGALREFEVAGERDPILPAK

Specific function: Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and an heterodisulfide [H]

COG id: COG4058

COG function: function code H; Methyl coenzyme M reductase, alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022681
- InterPro:   IPR016212
- InterPro:   IPR008924
- InterPro:   IPR009047
- InterPro:   IPR003183
- InterPro:   IPR015811
- InterPro:   IPR015823
- InterPro:   IPR009024 [H]

Pfam domain/function: PF02249 MCR_alpha; PF02745 MCR_alpha_N [H]

EC number: =2.8.4.1 [H]

Molecular weight: Translated: 60711; Mature: 60711

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAEKKLFLKALKEKFDEDPKEKYTKFYTYGGWKQSKRKTEFVEAAKDIADKRGGMPGYN
CCHHHHHHHHHHHHHHCCCHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
PDIGVPLGQRKMMSYKLSGTDDYVEGDDLHFMNNAAIQQLHDDIRRTVIVGMDTGHMVLE
CCCCCCCCCCHHEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHEEEEECCCCHHHHH
KRLGVEVTPETINEYMETINHALPGGAVVQEHMVEVDPALAWDSYAKIFTGDDELADELD
HHCCCEECHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHCCCHHEECCCHHHHHHHH
KRVLVDINKLFPEEQAEELKAAIGKKTYQISRVPTLVGRVCDGGTIARWSAMQIGMSFIT
HHHHHHHHHHCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AYKLCAGEAAIADFSYAAKHADVIGMGTALPARRSRGANEPGGIPFGILCDVVQTTRISD
HHHHHCCCHHHHHHHHHHHHCCEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHCCCC
DPVEQSLEVVATGAMLYDQIWLGAYMSGGVGFTQYATAAYTDDILDDFCYYGLDYVEKKF
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
GRCGTKATMDVVEDIATEVTLYSLEQYDEYPTLLEDHFGGSQRAAVAAAAAGVSVCMATG
HCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHEEEEEEC
NSNAGVNGWYLSQIMHKEYHSRLGFYGYDLQDQCGASNSLSIRNDESSPLELRGPNYPNY
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCEEECCCCCCEEECCCCCCCH
AMNVGHQGEYAGITQAAHSARGDAFAMNPLIKVAFADPSLIFDFARPRKCCARGALREFE
HCCCCCCCCCCHHHHHHHHCCCCEEEECCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHH
VAGERDPILPAK
CCCCCCCCCCCC
>Mature Secondary Structure
MEAEKKLFLKALKEKFDEDPKEKYTKFYTYGGWKQSKRKTEFVEAAKDIADKRGGMPGYN
CCHHHHHHHHHHHHHHCCCHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
PDIGVPLGQRKMMSYKLSGTDDYVEGDDLHFMNNAAIQQLHDDIRRTVIVGMDTGHMVLE
CCCCCCCCCCHHEEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHEEEEECCCCHHHHH
KRLGVEVTPETINEYMETINHALPGGAVVQEHMVEVDPALAWDSYAKIFTGDDELADELD
HHCCCEECHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHCCCHHEECCCHHHHHHHH
KRVLVDINKLFPEEQAEELKAAIGKKTYQISRVPTLVGRVCDGGTIARWSAMQIGMSFIT
HHHHHHHHHHCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AYKLCAGEAAIADFSYAAKHADVIGMGTALPARRSRGANEPGGIPFGILCDVVQTTRISD
HHHHHCCCHHHHHHHHHHHHCCEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHCCCC
DPVEQSLEVVATGAMLYDQIWLGAYMSGGVGFTQYATAAYTDDILDDFCYYGLDYVEKKF
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
GRCGTKATMDVVEDIATEVTLYSLEQYDEYPTLLEDHFGGSQRAAVAAAAAGVSVCMATG
HCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHEEEEEEC
NSNAGVNGWYLSQIMHKEYHSRLGFYGYDLQDQCGASNSLSIRNDESSPLELRGPNYPNY
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCEEECCCCCCEEECCCCCCCH
AMNVGHQGEYAGITQAAHSARGDAFAMNPLIKVAFADPSLIFDFARPRKCCARGALREFE
HCCCCCCCCCCHHHHHHHHCCCCEEEECCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHH
VAGERDPILPAK
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3185509 [H]