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The map label for this gene is pth

Identifier: 150401673

GI number: 150401673

Start: 1314732

End: 1315082

Strand: Direct

Name: pth

Synonym: Maeo_1251

Alternate gene names: 150401673

Gene position: 1314732-1315082 (Clockwise)

Preceding gene: 150401671

Following gene: 150401675

Centisome position: 83.77

GC content: 33.05

Gene sequence:

>351_bases
ATGTATAAACAGGTAATAATTTTAAGAAATGATTTAAAAATGGGAAAAGGCAAGTTGGTGGCACAGGGCAGTCATGCCTC
CCTTATATCTTTTTTAAATACTCAGAAAAATAACCCTTCGGTTGCCAAAGAATGGCTAAATGAAGGTCAAAAAAAAGTAG
TATTAAAAGTTAATTCTGAAAAAGAATTATTTGAGGTGTTTAGAGATGCAAATATTGATGGTTTTTCATGCTGTTTAATT
AGAGACGCAGGACATACCCAAATACCTTCGGGGACAGCAACGGCTGTTGGAATAGGTCCAGATAAAGAGGAAAAACTGGA
AAAAATAACAGGTAAATTAAAGTTATTATAA

Upstream 100 bases:

>100_bases
TTATGCAGATAAGACCATATTTTATTAATACGCCTTATCGCACTAATATTTGGGACAATAAAGGGACAATTTTTGAAGAC
TAACTATAAATGGTGATTTA

Downstream 100 bases:

>100_bases
TGTTATTTTTTAAATATTTTTTCAAGATTTACATTATTTTCAATAATTTCCGCAAATTTATTAATATTTTTTTCAAAATT
ATCTTTATAATTATCCTCGG

Product: peptidyl-tRNA hydrolase

Products: NA

Alternate protein names: PTH

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MYKQVIILRNDLKMGKGKLVAQGSHASLISFLNTQKNNPSVAKEWLNEGQKKVVLKVNSEKELFEVFRDANIDGFSCCLI
RDAGHTQIPSGTATAVGIGPDKEEKLEKITGKLKLL

Sequences:

>Translated_116_residues
MYKQVIILRNDLKMGKGKLVAQGSHASLISFLNTQKNNPSVAKEWLNEGQKKVVLKVNSEKELFEVFRDANIDGFSCCLI
RDAGHTQIPSGTATAVGIGPDKEEKLEKITGKLKLL
>Mature_116_residues
MYKQVIILRNDLKMGKGKLVAQGSHASLISFLNTQKNNPSVAKEWLNEGQKKVVLKVNSEKELFEVFRDANIDGFSCCLI
RDAGHTQIPSGTATAVGIGPDKEEKLEKITGKLKLL

Specific function: The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis

COG id: COG1990

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTH2 family

Homologues:

Organism=Homo sapiens, GI7706351, Length=114, Percent_Identity=45.6140350877193, Blast_Score=111, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17558188, Length=118, Percent_Identity=37.2881355932203, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319414, Length=119, Percent_Identity=39.4957983193277, Blast_Score=91, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281376919, Length=115, Percent_Identity=39.1304347826087, Blast_Score=99, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24644665, Length=115, Percent_Identity=39.1304347826087, Blast_Score=99, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24646438, Length=117, Percent_Identity=39.3162393162393, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PTH_META3 (A6UWF5)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001325439.1
- ProteinModelPortal:   A6UWF5
- SMR:   A6UWF5
- STRING:   A6UWF5
- GeneID:   5326346
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_1251
- eggNOG:   arNOG11345
- HOGENOM:   HBG526257
- OMA:   IQRRNPE
- ProtClustDB:   PRK04322
- BioCyc:   MAEO419665:MAEO_1251-MONOMER
- GO:   GO:0005737
- GO:   GO:0006412
- HAMAP:   MF_00628
- InterPro:   IPR002833
- TIGRFAMs:   TIGR00283

Pfam domain/function: PF01981 PTH2

EC number: =3.1.1.29

Molecular weight: Translated: 12782; Mature: 12782

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKQVIILRNDLKMGKGKLVAQGSHASLISFLNTQKNNPSVAKEWLNEGQKKVVLKVNSE
CCCEEEEEECCCCCCCCEEEECCCHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEEECCC
KELFEVFRDANIDGFSCCLIRDAGHTQIPSGTATAVGIGPDKEEKLEKITGKLKLL
HHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHEECC
>Mature Secondary Structure
MYKQVIILRNDLKMGKGKLVAQGSHASLISFLNTQKNNPSVAKEWLNEGQKKVVLKVNSE
CCCEEEEEECCCCCCCCEEEECCCHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEEECCC
KELFEVFRDANIDGFSCCLIRDAGHTQIPSGTATAVGIGPDKEEKLEKITGKLKLL
HHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA