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The map label for this gene is gcp [H]

Identifier: 150401621

GI number: 150401621

Start: 1265896

End: 1267530

Strand: Direct

Name: gcp [H]

Synonym: Maeo_1198

Alternate gene names: 150401621

Gene position: 1265896-1267530 (Clockwise)

Preceding gene: 150401619

Following gene: 150401622

Centisome position: 80.66

GC content: 32.91

Gene sequence:

>1635_bases
ATGATTTGTATTGGATTAGAAGGAACAGCGGAAAAAACAGGAGTTGGTGTGGTTGACTCAGGTGGAACTGTATTATTTAA
TAAAACTATAATATATAAACCACCAGTTCAAGGTATAAATCCAAGGGAGGCAGCAGACCACCATGCCGAGACATTTCCAA
AATTAATTGAGGAAGCATTAAAGGTAATTCCAAAAGAAAAAATTGATTTAATAGCATTTTCCCAAGGTCCGGGGTTGGGT
CCAAGTTTAAGAGTTAGTGCTACGGCTGGAAGAGCATTAGCCTTATCATTGAAAAAGCCTATAATCGGGGTTAATCATTG
TGTAGGGCATGTAGAAATTGGAAAACTAACAACTGGGGCAAAAGATCCATTAACATTATATGTCAGTGGAGGAAATACAC
AAGTATTGGGCTATGCAGGGGGGAGATATCGGGTTTTTGGTGAAACTCTTGATATAGCAATAGGTAATTGTTTAGACCAG
TTTGCGAGAAATTGTGGACTTCCACACCCAGGGGGAGTTTTTGTTGAACAAAAGGCAAAAGAAAGTAGCAAAAAATTAAT
AAAATTGCCATACAGTGTTAAAGGGATGGATATTACTTTTTCTGGACTTTTAACTTCTTCTATCAAAGCCATAAAAGATA
AACACGAAAAAATAGAGGATGTTTGTTATTCTCTTCAAGAAACTGCATTTTCAATGATAACGGAAATTACTGAACGAGCT
TTGGCACATACAAATAAGCCAGAAGTGATGTTGGTAGGCGGGGTAGCCGCAAACAATAGATTGAGGGAGATGCTAAGTAT
CATGTGTGGTGAGCAAAATGTGGAATTTCATGTTCCTGAGCCACAATTTTGTGGGGATAATGGTGCAATGATAGCTTGGC
TGGGTTTATTACAATATATCAATGGAAAAAGAATGGATATAATGGATACTAAAATAAATCCTGTTTATAGAAGTGATATG
GTAGAAGTTAATTGGATTAATGGTAAAAATAACTACGAATTAAAAAGAGAAATTCCGACCCATTTAATTGGGAAGGGGGC
AGAGGCAGATATTAAAAAAATAAAATATTTGGACTGGGATTCCATAACAAAGGAAAGAGTGGTAAAAAATTATCGAGTAA
AAGAATTGGATAAATTAATAAGAACGGAAAGAACTATAAAAGAAAGTAGATTTTTAAATATAATTAAGGATTTTTTTATT
TCCGCTCCGTTTGTTTATGATATTGATAAAAAAAATACAACAATTACAATGAGTTATATTTCTGGAAAAATGGCAAAAGA
AATAATTGATGGAGGGGATTTATCTTGCTGTAATAAAATTGGAAAAATTATTGGGGAGCTCCATAAAAATAATATTATCC
ACAATGATTTAACTACCTCTAATTTTATGGTGGAAAAGGAAAAAAAAGGCAATAACAAAGTTTATATTATAGATTTTGGG
CTTGGAACATACTCCAACCTAATCGAAAATAAAGCCGTAGATTTAATTGTGCTAAAAAAATCTATTTTAAGCACTCATTT
TGATAAATTTGAAGAAATATGGGATAAAATAATAGATGGTTATAAAATATATCCAGAATGGGAAAAAGTATTGAAACATA
TGGAAGATGTTGAAAAAAGAGCAAGATATGTATAG

Upstream 100 bases:

>100_bases
GTATATTATATGTATTATATTTATTATTGTATTTTCATTGCATTCTTATTGTATTCATTATTATATTTATTATTGTATCT
AAATTATATTATGTGAAACT

Downstream 100 bases:

>100_bases
ACAATCTGTGGGAGCTCCAATATTAGTAGGGAGCTCCATATAGTAAAATATTCACATACCATAAATATAGTAAGTTCAAT
AACTGTCCCTTATCCGTCCA

Product: O-sialoglycoprotein endopeptidase/protein kinase

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MICIGLEGTAEKTGVGVVDSGGTVLFNKTIIYKPPVQGINPREAADHHAETFPKLIEEALKVIPKEKIDLIAFSQGPGLG
PSLRVSATAGRALALSLKKPIIGVNHCVGHVEIGKLTTGAKDPLTLYVSGGNTQVLGYAGGRYRVFGETLDIAIGNCLDQ
FARNCGLPHPGGVFVEQKAKESSKKLIKLPYSVKGMDITFSGLLTSSIKAIKDKHEKIEDVCYSLQETAFSMITEITERA
LAHTNKPEVMLVGGVAANNRLREMLSIMCGEQNVEFHVPEPQFCGDNGAMIAWLGLLQYINGKRMDIMDTKINPVYRSDM
VEVNWINGKNNYELKREIPTHLIGKGAEADIKKIKYLDWDSITKERVVKNYRVKELDKLIRTERTIKESRFLNIIKDFFI
SAPFVYDIDKKNTTITMSYISGKMAKEIIDGGDLSCCNKIGKIIGELHKNNIIHNDLTTSNFMVEKEKKGNNKVYIIDFG
LGTYSNLIENKAVDLIVLKKSILSTHFDKFEEIWDKIIDGYKIYPEWEKVLKHMEDVEKRARYV

Sequences:

>Translated_544_residues
MICIGLEGTAEKTGVGVVDSGGTVLFNKTIIYKPPVQGINPREAADHHAETFPKLIEEALKVIPKEKIDLIAFSQGPGLG
PSLRVSATAGRALALSLKKPIIGVNHCVGHVEIGKLTTGAKDPLTLYVSGGNTQVLGYAGGRYRVFGETLDIAIGNCLDQ
FARNCGLPHPGGVFVEQKAKESSKKLIKLPYSVKGMDITFSGLLTSSIKAIKDKHEKIEDVCYSLQETAFSMITEITERA
LAHTNKPEVMLVGGVAANNRLREMLSIMCGEQNVEFHVPEPQFCGDNGAMIAWLGLLQYINGKRMDIMDTKINPVYRSDM
VEVNWINGKNNYELKREIPTHLIGKGAEADIKKIKYLDWDSITKERVVKNYRVKELDKLIRTERTIKESRFLNIIKDFFI
SAPFVYDIDKKNTTITMSYISGKMAKEIIDGGDLSCCNKIGKIIGELHKNNIIHNDLTTSNFMVEKEKKGNNKVYIIDFG
LGTYSNLIENKAVDLIVLKKSILSTHFDKFEEIWDKIIDGYKIYPEWEKVLKHMEDVEKRARYV
>Mature_544_residues
MICIGLEGTAEKTGVGVVDSGGTVLFNKTIIYKPPVQGINPREAADHHAETFPKLIEEALKVIPKEKIDLIAFSQGPGLG
PSLRVSATAGRALALSLKKPIIGVNHCVGHVEIGKLTTGAKDPLTLYVSGGNTQVLGYAGGRYRVFGETLDIAIGNCLDQ
FARNCGLPHPGGVFVEQKAKESSKKLIKLPYSVKGMDITFSGLLTSSIKAIKDKHEKIEDVCYSLQETAFSMITEITERA
LAHTNKPEVMLVGGVAANNRLREMLSIMCGEQNVEFHVPEPQFCGDNGAMIAWLGLLQYINGKRMDIMDTKINPVYRSDM
VEVNWINGKNNYELKREIPTHLIGKGAEADIKKIKYLDWDSITKERVVKNYRVKELDKLIRTERTIKESRFLNIIKDFFI
SAPFVYDIDKKNTTITMSYISGKMAKEIIDGGDLSCCNKIGKIIGELHKNNIIHNDLTTSNFMVEKEKKGNNKVYIIDFG
LGTYSNLIENKAVDLIVLKKSILSTHFDKFEEIWDKIIDGYKIYPEWEKVLKHMEDVEKRARYV

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI8923380, Length=331, Percent_Identity=45.9214501510574, Blast_Score=298, Evalue=1e-80,
Organism=Homo sapiens, GI116812636, Length=351, Percent_Identity=30.4843304843305, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI41327715, Length=212, Percent_Identity=31.6037735849057, Blast_Score=105, Evalue=8e-23,
Organism=Escherichia coli, GI1789445, Length=321, Percent_Identity=31.4641744548287, Blast_Score=154, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI71995670, Length=336, Percent_Identity=49.1071428571429, Blast_Score=325, Evalue=5e-89,
Organism=Caenorhabditis elegans, GI17557464, Length=353, Percent_Identity=25.7790368271955, Blast_Score=86, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6322891, Length=368, Percent_Identity=43.75, Blast_Score=282, Evalue=9e-77,
Organism=Saccharomyces cerevisiae, GI6320099, Length=338, Percent_Identity=28.9940828402367, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6321701, Length=214, Percent_Identity=32.2429906542056, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI21357207, Length=346, Percent_Identity=44.7976878612717, Blast_Score=300, Evalue=2e-81,
Organism=Drosophila melanogaster, GI20129063, Length=343, Percent_Identity=27.4052478134111, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24658177, Length=216, Percent_Identity=32.8703703703704, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022449
- InterPro:   IPR022495
- InterPro:   IPR011009
- InterPro:   IPR009220
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- InterPro:   IPR000719
- InterPro:   IPR018934
- InterPro:   IPR008266 [H]

Pfam domain/function: PF00814 Peptidase_M22; PF01163 RIO1 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 60805; Mature: 60805

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS00109 PROTEIN_KINASE_TYR ; PS50011 PROTEIN_KINASE_DOM ; PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICIGLEGTAEKTGVGVVDSGGTVLFNKTIIYKPPVQGINPREAADHHAETFPKLIEEAL
CEEECCCCCCCCCCCEEEECCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
KVIPKEKIDLIAFSQGPGLGPSLRVSATAGRALALSLKKPIIGVNHCVGHVEIGKLTTGA
HHCCCCCEEEEEEECCCCCCCCEEEEECCCCEEEEECCCCCEEHHHCCCEEEECCCCCCC
KDPLTLYVSGGNTQVLGYAGGRYRVFGETLDIAIGNCLDQFARNCGLPHPGGVFVEQKAK
CCCEEEEEECCCEEEEEECCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHH
ESSKKLIKLPYSVKGMDITFSGLLTSSIKAIKDKHEKIEDVCYSLQETAFSMITEITERA
HHCCCEEECCCEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAHTNKPEVMLVGGVAANNRLREMLSIMCGEQNVEFHVPEPQFCGDNGAMIAWLGLLQYI
HHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHH
NGKRMDIMDTKINPVYRSDMVEVNWINGKNNYELKREIPTHLIGKGAEADIKKIKYLDWD
CCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHCCHHHHCCCCCCHHHHEEECCCH
SITKERVVKNYRVKELDKLIRTERTIKESRFLNIIKDFFISAPFVYDIDKKNTTITMSYI
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEHHH
SGKMAKEIIDGGDLSCCNKIGKIIGELHKNNIIHNDLTTSNFMVEKEKKGNNKVYIIDFG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCEEEEEEEC
LGTYSNLIENKAVDLIVLKKSILSTHFDKFEEIWDKIIDGYKIYPEWEKVLKHMEDVEKR
CCHHHHHHHCCCHHHEEHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHH
ARYV
HCCC
>Mature Secondary Structure
MICIGLEGTAEKTGVGVVDSGGTVLFNKTIIYKPPVQGINPREAADHHAETFPKLIEEAL
CEEECCCCCCCCCCCEEEECCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
KVIPKEKIDLIAFSQGPGLGPSLRVSATAGRALALSLKKPIIGVNHCVGHVEIGKLTTGA
HHCCCCCEEEEEEECCCCCCCCEEEEECCCCEEEEECCCCCEEHHHCCCEEEECCCCCCC
KDPLTLYVSGGNTQVLGYAGGRYRVFGETLDIAIGNCLDQFARNCGLPHPGGVFVEQKAK
CCCEEEEEECCCEEEEEECCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHH
ESSKKLIKLPYSVKGMDITFSGLLTSSIKAIKDKHEKIEDVCYSLQETAFSMITEITERA
HHCCCEEECCCEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAHTNKPEVMLVGGVAANNRLREMLSIMCGEQNVEFHVPEPQFCGDNGAMIAWLGLLQYI
HHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHH
NGKRMDIMDTKINPVYRSDMVEVNWINGKNNYELKREIPTHLIGKGAEADIKKIKYLDWD
CCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCHHHHCCHHHHCCCCCCHHHHEEECCCH
SITKERVVKNYRVKELDKLIRTERTIKESRFLNIIKDFFISAPFVYDIDKKNTTITMSYI
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEHHH
SGKMAKEIIDGGDLSCCNKIGKIIGELHKNNIIHNDLTTSNFMVEKEKKGNNKVYIIDFG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCEEEEEEEC
LGTYSNLIENKAVDLIVLKKSILSTHFDKFEEIWDKIIDGYKIYPEWEKVLKHMEDVEKR
CCHHHHHHHCCCHHHEEHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHH
ARYV
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA