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The map label for this gene is kefC [C]

Identifier: 150401172

GI number: 150401172

Start: 763419

End: 764606

Strand: Direct

Name: kefC [C]

Synonym: Maeo_0743

Alternate gene names: 150401172

Gene position: 763419-764606 (Clockwise)

Preceding gene: 150401171

Following gene: 150401173

Centisome position: 48.64

GC content: 29.63

Gene sequence:

>1188_bases
GTGGATGAATATTTTATGTTTTTTATAATAATATCATGTATATTGTTAATCCCAGAAATACTAAAAAAATTCAATATCCC
TGGCATCACTTCCGTAATGTTGGCTGGTATTATTATAGGCCCATATGGAATTGGACTAGTTAAATTGGATGCAGCATTAG
AAATATTCGCAATGTTTGGAGCAATATTTTTAATGTTTTTAGCCGGAATGGAATTAGACAATAAAACATTAAAAGAAGAA
TTTAAAAATTCAACATTTATAGCATTTTCTTCGTTAATTTTACCTGCTATTGGAGGATATGCCATAGGAAAACTTTTTGG
ATTAAATACCATTGGGGCCCTACTATATGCAGCAATATTTTCGTCCCATTCTATTGGAATAATATATAGTTTAATGGATG
AATTGAATATGATAAAATCACGGTTTGGAACCACGGCATTAAGTGCTACAATTCTTGTTGATTTGTTTAGTTTGATAGCT
TTATCTGCAATAATAAAAATGAGCTCTGCAACTCAAAATTTAGATATAGTATATTTCATATTGATGGTATTTGGATATAT
TATTTCTCTTTTAATATTCATACCATTTATTTCAAAAATAATATTCAAAAAATTTGCTAAATTGCATGTGCAAAAAATAC
ATTTCGTATTATTTATAATATTTATATCAATACTTGCGGGAGAATATATCGGCCTACATCCAATAATTGGGGCGTTTATA
ACTGGAATTGCAGTTTCAGAAGCGTTATCAAAAGAAGAACATGATAAACTATTAAATAATAATTTAAATGCAATAGGTTA
TGGTTTCTTTATACCGATATTTTTCCTTACGCTGGGCATGACGACAGATATTAGTGTATTATATGATTTAAACAATATAT
GGTTAATATTGGCAACAATAATAACAGCATCGGTTTTAAAAATAGGTTCTGGATATACATCTTTCAGAATATTGAAATAT
GACAAGATAAAAAGTTTATGTGGTGGGTTATTGACCATGCCCAAAATATCTGCATCATTAGTTGCTGCATCTGTTGGACT
TGAACTTGGAATTTTATCACGAGAATTTTTCGTGGCAATAGTGGTTTTATCAATTCTTAGCTCCATGATAACCCCAATTT
TTGTAAAAAACCTCGTAGTTAAAAATAGTTCGGCATTTGTGGACAAATGCAACGAGGAAAAGCGATAA

Upstream 100 bases:

>100_bases
CAGAAGTGTTTCAAGTAGGTTAAAAGACACAAGTGATAAGATAGAGCGGGAAATTATCCGAAAAAAGAGGAAAATATCTT
AATCTGCAAAGGGGGAAATC

Downstream 100 bases:

>100_bases
AACGACAAGAAAATTAAAACATCTTTAAATAATAATATATACATAAAAAATACACAAATATATATTATATATTTATAATA
TTTTTTTCTATTCAAAGAAC

Product: sodium/hydrogen exchanger

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: MjNapA [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MDEYFMFFIIISCILLIPEILKKFNIPGITSVMLAGIIIGPYGIGLVKLDAALEIFAMFGAIFLMFLAGMELDNKTLKEE
FKNSTFIAFSSLILPAIGGYAIGKLFGLNTIGALLYAAIFSSHSIGIIYSLMDELNMIKSRFGTTALSATILVDLFSLIA
LSAIIKMSSATQNLDIVYFILMVFGYIISLLIFIPFISKIIFKKFAKLHVQKIHFVLFIIFISILAGEYIGLHPIIGAFI
TGIAVSEALSKEEHDKLLNNNLNAIGYGFFIPIFFLTLGMTTDISVLYDLNNIWLILATIITASVLKIGSGYTSFRILKY
DKIKSLCGGLLTMPKISASLVAASVGLELGILSREFFVAIVVLSILSSMITPIFVKNLVVKNSSAFVDKCNEEKR

Sequences:

>Translated_395_residues
MDEYFMFFIIISCILLIPEILKKFNIPGITSVMLAGIIIGPYGIGLVKLDAALEIFAMFGAIFLMFLAGMELDNKTLKEE
FKNSTFIAFSSLILPAIGGYAIGKLFGLNTIGALLYAAIFSSHSIGIIYSLMDELNMIKSRFGTTALSATILVDLFSLIA
LSAIIKMSSATQNLDIVYFILMVFGYIISLLIFIPFISKIIFKKFAKLHVQKIHFVLFIIFISILAGEYIGLHPIIGAFI
TGIAVSEALSKEEHDKLLNNNLNAIGYGFFIPIFFLTLGMTTDISVLYDLNNIWLILATIITASVLKIGSGYTSFRILKY
DKIKSLCGGLLTMPKISASLVAASVGLELGILSREFFVAIVVLSILSSMITPIFVKNLVVKNSSAFVDKCNEEKR
>Mature_395_residues
MDEYFMFFIIISCILLIPEILKKFNIPGITSVMLAGIIIGPYGIGLVKLDAALEIFAMFGAIFLMFLAGMELDNKTLKEE
FKNSTFIAFSSLILPAIGGYAIGKLFGLNTIGALLYAAIFSSHSIGIIYSLMDELNMIKSRFGTTALSATILVDLFSLIA
LSAIIKMSSATQNLDIVYFILMVFGYIISLLIFIPFISKIIFKKFAKLHVQKIHFVLFIIFISILAGEYIGLHPIIGAFI
TGIAVSEALSKEEHDKLLNNNLNAIGYGFFIPIFFLTLGMTTDISVLYDLNNIWLILATIITASVLKIGSGYTSFRILKY
DKIKSLCGGLLTMPKISASLVAASVGLELGILSREFFVAIVVLSILSSMITPIFVKNLVVKNSSAFVDKCNEEKR

Specific function: This is probably a Na(+)/H(+) antiporter [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Escherichia coli, GI1786232, Length=300, Percent_Identity=24.3333333333333, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322367, Length=376, Percent_Identity=27.1276595744681, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 43387; Mature: 43387

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEYFMFFIIISCILLIPEILKKFNIPGITSVMLAGIIIGPYGIGLVKLDAALEIFAMFG
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AIFLMFLAGMELDNKTLKEEFKNSTFIAFSSLILPAIGGYAIGKLFGLNTIGALLYAAIF
HHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSHSIGIIYSLMDELNMIKSRFGTTALSATILVDLFSLIALSAIIKMSSATQNLDIVYFI
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LMVFGYIISLLIFIPFISKIIFKKFAKLHVQKIHFVLFIIFISILAGEYIGLHPIIGAFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
TGIAVSEALSKEEHDKLLNNNLNAIGYGFFIPIFFLTLGMTTDISVLYDLNNIWLILATI
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHEEEHHHHHHHHHHH
ITASVLKIGSGYTSFRILKYDKIKSLCGGLLTMPKISASLVAASVGLELGILSREFFVAI
HHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVLSILSSMITPIFVKNLVVKNSSAFVDKCNEEKR
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCC
>Mature Secondary Structure
MDEYFMFFIIISCILLIPEILKKFNIPGITSVMLAGIIIGPYGIGLVKLDAALEIFAMFG
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AIFLMFLAGMELDNKTLKEEFKNSTFIAFSSLILPAIGGYAIGKLFGLNTIGALLYAAIF
HHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSHSIGIIYSLMDELNMIKSRFGTTALSATILVDLFSLIALSAIIKMSSATQNLDIVYFI
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
LMVFGYIISLLIFIPFISKIIFKKFAKLHVQKIHFVLFIIFISILAGEYIGLHPIIGAFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
TGIAVSEALSKEEHDKLLNNNLNAIGYGFFIPIFFLTLGMTTDISVLYDLNNIWLILATI
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHEEEHHHHHHHHHHH
ITASVLKIGSGYTSFRILKYDKIKSLCGGLLTMPKISASLVAASVGLELGILSREFFVAI
HHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVLSILSSMITPIFVKNLVVKNSSAFVDKCNEEKR
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]