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The map label for this gene is cmk [H]

Identifier: 150398643

GI number: 150398643

Start: 3665023

End: 3665661

Strand: Direct

Name: cmk [H]

Synonym: Smed_3457

Alternate gene names: 150398643

Gene position: 3665023-3665661 (Clockwise)

Preceding gene: 150398642

Following gene: 150398644

Centisome position: 96.91

GC content: 64.79

Gene sequence:

>639_bases
ATGAGCTTCGTAGTCGCCATCGACGGACCCGCAGCCGCCGGCAAGGGAACGCTGTCGCGCCTGATCGCCAAGCGGTACGG
CTTTCACCATCTCGACACCGGACTCACCTATCGCGCCGCCGCCAAGGCACTCATCGATGCCGGATTACCGCTCGACGATG
AGGCGGTAGCCGAGAAGACGGCCCGTCAGGTCGACCTTTCCGGCCTGGATCGTGCCGTGCTTTCGGCCCATGCGATCGGC
GAGGCGGCATCCAAGATCGCGGTCATGCCGGCCGTGCGCCGGGCACTGGTCGAGGCGCAGCGCGCCTTCGCGCTGAAGGA
GCCGGGTACCGTCCTCGACGGGCGCGATATCGGCACGGTCGTCTGCCCCGACGCGGCGGTGAAGCTCTATGTCACAGCTT
CTCCCGAAGTGCGGGCGAAGCGGCGCTATGACGAGATCGTCACCGGCGGCGGAACGGCCGACTACACCACGATTTTCGAG
GACGTGAAGAAGCGGGACACGCGCGATATGGGCCGTGCCGACAGCCCCTTGAGACCGGCCGAGGACGCGCACTTGCTTGA
TACTTCCGAAATGAGTATAGAGGCGGCATTCCAGGCGGCGAAGACGCTGATCGACGTTGCCCTGAATAAGACGATTTGA

Upstream 100 bases:

>100_bases
TCGACGATGCGACGATGATCGCGACGTCCTTCCCCGAGTTCATGGGACTGATGACAGGGTTGGGCGCGAAGATCGAAGAG
ACGGAAAACAAGGCGGCCCT

Downstream 100 bases:

>100_bases
AGAAAGGCTCTTCTTCGGTCCGACCGATATTGCCTTCTTGAAATAAGCCTGAAATTCCGTCCACGCGCCGGATTGCTCCA
TGATAGGAGCGGACTGGGTT

Product: cytidylate kinase

Products: NA

Alternate protein names: CK; Cytidine monophosphate kinase; CMP kinase [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSFVVAIDGPAAAGKGTLSRLIAKRYGFHHLDTGLTYRAAAKALIDAGLPLDDEAVAEKTARQVDLSGLDRAVLSAHAIG
EAASKIAVMPAVRRALVEAQRAFALKEPGTVLDGRDIGTVVCPDAAVKLYVTASPEVRAKRRYDEIVTGGGTADYTTIFE
DVKKRDTRDMGRADSPLRPAEDAHLLDTSEMSIEAAFQAAKTLIDVALNKTI

Sequences:

>Translated_212_residues
MSFVVAIDGPAAAGKGTLSRLIAKRYGFHHLDTGLTYRAAAKALIDAGLPLDDEAVAEKTARQVDLSGLDRAVLSAHAIG
EAASKIAVMPAVRRALVEAQRAFALKEPGTVLDGRDIGTVVCPDAAVKLYVTASPEVRAKRRYDEIVTGGGTADYTTIFE
DVKKRDTRDMGRADSPLRPAEDAHLLDTSEMSIEAAFQAAKTLIDVALNKTI
>Mature_211_residues
SFVVAIDGPAAAGKGTLSRLIAKRYGFHHLDTGLTYRAAAKALIDAGLPLDDEAVAEKTARQVDLSGLDRAVLSAHAIGE
AASKIAVMPAVRRALVEAQRAFALKEPGTVLDGRDIGTVVCPDAAVKLYVTASPEVRAKRRYDEIVTGGGTADYTTIFED
VKKRDTRDMGRADSPLRPAEDAHLLDTSEMSIEAAFQAAKTLIDVALNKTI

Specific function: ATP, Datp, And GTP Are Equally Effective As Phosphate Donors. CMP And Dcmp Are The Best Phosphate Acceptors. [C]

COG id: COG0283

COG function: function code F; Cytidylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylate kinase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787139, Length=211, Percent_Identity=40.2843601895735, Blast_Score=137, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000850
- InterPro:   IPR003136
- InterPro:   IPR011994 [H]

Pfam domain/function: PF00406 ADK; PF02224 Cytidylate_kin [H]

EC number: =2.7.4.14 [H]

Molecular weight: Translated: 22532; Mature: 22401

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFVVAIDGPAAAGKGTLSRLIAKRYGFHHLDTGLTYRAAAKALIDAGLPLDDEAVAEKT
CEEEEEECCCCCCCHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
ARQVDLSGLDRAVLSAHAIGEAASKIAVMPAVRRALVEAQRAFALKEPGTVLDGRDIGTV
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEE
VCPDAAVKLYVTASPEVRAKRRYDEIVTGGGTADYTTIFEDVKKRDTRDMGRADSPLRPA
ECCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
EDAHLLDTSEMSIEAAFQAAKTLIDVALNKTI
CCCEECCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SFVVAIDGPAAAGKGTLSRLIAKRYGFHHLDTGLTYRAAAKALIDAGLPLDDEAVAEKT
EEEEEECCCCCCCHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
ARQVDLSGLDRAVLSAHAIGEAASKIAVMPAVRRALVEAQRAFALKEPGTVLDGRDIGTV
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEE
VCPDAAVKLYVTASPEVRAKRRYDEIVTGGGTADYTTIFEDVKKRDTRDMGRADSPLRPA
ECCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
EDAHLLDTSEMSIEAAFQAAKTLIDVALNKTI
CCCEECCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]