Click here to switch to the map view.

The map label for this gene is ykfC [H]

Identifier: 150398550

GI number: 150398550

Start: 3560609

End: 3561475

Strand: Direct

Name: ykfC [H]

Synonym: Smed_3361

Alternate gene names: 150398550

Gene position: 3560609-3561475 (Clockwise)

Preceding gene: 150398549

Following gene: 150398556

Centisome position: 94.15

GC content: 65.17

Gene sequence:

>867_bases
ATGAGCTCGCCAATGCCAGAAGTTCTCGATCGCCGTCTCAATGCCTATCGCGAAGACCTCGCGGAGGAGCGTCTGCGCGG
CATCGTCGAGGCGAAGCGCTTCGTGGAAGGCACGCCGGCGGCAGTGGCTGTGCCGGTGACGCCGCTCCGTCCGAGGCCGG
AGGCCGATTGCGGCACCGATACCGAGCTGCTTTATGGCGAGACGCTGCGCATACTCGACGTCGCCGGCGGATGGGCGTGG
GTCAAATCCGACCTCGACGGCTATGTCGGCTACGTACCGCAGGATCTGCTGAAGCCTGCGCACTCCGCGGCAACGCACAT
CGTCTCGGTGCCGCGGACATTCGTCTATCGCGGCGCGGATCTGCGTTTTCCCCAGGTCCATGCTCTTTCCATGGGGAGCC
GGGTTGAGGTCGTCGGGGAGACCGAGACGCGCGGCACGCGCTATTTTCTGCTGGAAGGCGGGCTGGCGATCGTCGCCGAT
CATTGCATCCAGGCCGGCAATCCGCTCACGGACGACTATGTCGCGGTCGCGTCCCGCTTTATCGAGACGCCTTATCTTTG
GGGCGGCCGCTCCGGGTTCGGCATCGACTGTTCGGGCCTTGTGCAACTCGCGATGCAGATGACCGGGCGCAATGCGCCGC
GCGACTCCGATATGCAGGCAAGGGACCTCGGCCGCGTCATCGAGCGCGAGGGACTCACGCGCGGCGACCTCGTCTTCTGG
AAGGGCCATGTGGCGATCATGGAAGACGAGAAGACGCTGATACATGCCAATGGCCACACGATGACGGTGGCGCGGGAAGG
TCTCGAAGACGCCATCCGGCGCATCGGCTGGCTGTATGCGCAGCCGACGGGATACAGGCGGCCCTAG

Upstream 100 bases:

>100_bases
ACGAGCGCGACAGGCGCAATGTCATCATCAAGCGCACTTTGGAAGGTGCTCTCTATCTTGAAAAATTCGGCGATCTGATC
ATCAATCAAGGCCGGAAACT

Downstream 100 bases:

>100_bases
GGGCGCAGCAACGGTCAGGCTTTATTGCCGGCATGATCGCCCGCAGATTTGCCCCTTCAACCCTTGCCCTCTCCCCGTAC
GCGGGGGAGCGCGACCGGAC

Product: NLP/P60 protein

Products: NA

Alternate protein names: Cell wall endopeptidase ykfC [H]

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MSSPMPEVLDRRLNAYREDLAEERLRGIVEAKRFVEGTPAAVAVPVTPLRPRPEADCGTDTELLYGETLRILDVAGGWAW
VKSDLDGYVGYVPQDLLKPAHSAATHIVSVPRTFVYRGADLRFPQVHALSMGSRVEVVGETETRGTRYFLLEGGLAIVAD
HCIQAGNPLTDDYVAVASRFIETPYLWGGRSGFGIDCSGLVQLAMQMTGRNAPRDSDMQARDLGRVIEREGLTRGDLVFW
KGHVAIMEDEKTLIHANGHTMTVAREGLEDAIRRIGWLYAQPTGYRRP

Sequences:

>Translated_288_residues
MSSPMPEVLDRRLNAYREDLAEERLRGIVEAKRFVEGTPAAVAVPVTPLRPRPEADCGTDTELLYGETLRILDVAGGWAW
VKSDLDGYVGYVPQDLLKPAHSAATHIVSVPRTFVYRGADLRFPQVHALSMGSRVEVVGETETRGTRYFLLEGGLAIVAD
HCIQAGNPLTDDYVAVASRFIETPYLWGGRSGFGIDCSGLVQLAMQMTGRNAPRDSDMQARDLGRVIEREGLTRGDLVFW
KGHVAIMEDEKTLIHANGHTMTVAREGLEDAIRRIGWLYAQPTGYRRP
>Mature_287_residues
SSPMPEVLDRRLNAYREDLAEERLRGIVEAKRFVEGTPAAVAVPVTPLRPRPEADCGTDTELLYGETLRILDVAGGWAWV
KSDLDGYVGYVPQDLLKPAHSAATHIVSVPRTFVYRGADLRFPQVHALSMGSRVEVVGETETRGTRYFLLEGGLAIVADH
CIQAGNPLTDDYVAVASRFIETPYLWGGRSGFGIDCSGLVQLAMQMTGRNAPRDSDMQARDLGRVIEREGLTRGDLVFWK
GHVAIMEDEKTLIHANGHTMTVAREGLEDAIRRIGWLYAQPTGYRRP

Specific function: Specifically hydrolyzes gamma-D-glutamyl-L-lysine bonds in murein peptides, releasing L-Ala-D-Glu [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nlpC/p60 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064 [H]

Pfam domain/function: PF00877 NLPC_P60 [H]

EC number: NA

Molecular weight: Translated: 31864; Mature: 31732

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPMPEVLDRRLNAYREDLAEERLRGIVEAKRFVEGTPAAVAVPVTPLRPRPEADCGTD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCC
TELLYGETLRILDVAGGWAWVKSDLDGYVGYVPQDLLKPAHSAATHIVSVPRTFVYRGAD
CEEEECCCEEEEEECCCHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHCCHHHEECCCC
LRFPQVHALSMGSRVEVVGETETRGTRYFLLEGGLAIVADHCIQAGNPLTDDYVAVASRF
CCCCCEEEECCCCEEEEEECCCCCCCEEEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHH
IETPYLWGGRSGFGIDCSGLVQLAMQMTGRNAPRDSDMQARDLGRVIEREGLTRGDLVFW
HCCCCEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEE
KGHVAIMEDEKTLIHANGHTMTVAREGLEDAIRRIGWLYAQPTGYRRP
ECCEEEEECCCEEEEECCCEEEHHHHHHHHHHHHHHEEEECCCCCCCC
>Mature Secondary Structure 
SSPMPEVLDRRLNAYREDLAEERLRGIVEAKRFVEGTPAAVAVPVTPLRPRPEADCGTD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCC
TELLYGETLRILDVAGGWAWVKSDLDGYVGYVPQDLLKPAHSAATHIVSVPRTFVYRGAD
CEEEECCCEEEEEECCCHHHHHHCCCCHHCCCCHHHHHHHHHHHHHHHHCCHHHEECCCC
LRFPQVHALSMGSRVEVVGETETRGTRYFLLEGGLAIVADHCIQAGNPLTDDYVAVASRF
CCCCCEEEECCCCEEEEEECCCCCCCEEEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHH
IETPYLWGGRSGFGIDCSGLVQLAMQMTGRNAPRDSDMQARDLGRVIEREGLTRGDLVFW
HCCCCEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEE
KGHVAIMEDEKTLIHANGHTMTVAREGLEDAIRRIGWLYAQPTGYRRP
ECCEEEEECCCEEEEECCCEEEHHHHHHHHHHHHHHEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]