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The map label for this gene is accD [H]

Identifier: 150398431

GI number: 150398431

Start: 3413929

End: 3414843

Strand: Direct

Name: accD [H]

Synonym: Smed_3239

Alternate gene names: 150398431

Gene position: 3413929-3414843 (Clockwise)

Preceding gene: 150398430

Following gene: 150398432

Centisome position: 90.27

GC content: 60.66

Gene sequence:

>915_bases
TTGAACTGGATCACAAACTACGTTCGGCCGAAGATCAATTCGATGCTCGGTCGCAGGGAAGTTCCGGAGAACCTCTGGAT
CAAGTGCCCTGAAACGGGCGAGATGGTGTTCCATCGCGATCTCGAAGAGAACAAATGGGTCATCCCGCAATCCGGTTTTC
ATATGAAGATGCCGGCGAAGGCCCGCCTTAAGGATCTCTTCGACGGCGGTATTTACGAGGCGTTTCCGCAGCCGAAGGTG
GCGCAGGACCCGCTCAAGTTCCGCGATTCAAAGAAATACTCCGATCGCCTGCGCGACAGCCGTACCAAGACCGAGCTCGA
GGACACGATCGTTGCCGGCCTCGGCCAGGTGCAGGGGATCAAGCTCGTCGCGGTCGCTCATGAGTTCAACTTCATAGGCG
GATCACTCGGCATTGCCGCGGGCGAAGCGATCGTGAAGGCTTTCGAGCGGGCAATTGCCGAGAAGTGCCCGCTGGTCATG
TTCCCGGCTTCTGGCGGCGCTCGCATGCAGGAAGGCATCCTGTCGCTGATGCAGCTGCCGCGCACGACCGTCGCGGTGAA
CATGCTCAAGGAGGCGGGTCTTCCCTATATCGTCGTCCTGACGAATCCGACCACCGGTGGCGTCACGGCGTCCTATGCGA
TGCTGGGTGATGTCCACCTGGCTGAGCCTGGCGCGGAGATCGGCTTCGCCGGAAAGCGGGTGATCGAGCAGACGCTGCGG
GAAAAGCTCCCCGAGGGCTTCCAGACTTCCGAGTATCTGATGGAGCACGGCATGGTCGACATGGTCGTCAAACGCCACGA
TATCCCGGAGACGCTCGCCCGCGTGCTCAACATTCTCATGAAAAAGCCGGCCAAGGCGATCAAACGGGATACCGCTACCG
AGCTTGCGCCGCTGCCCGTGGCCGCGAGCGCCTAG

Upstream 100 bases:

>100_bases
GGCTTGCGGCCGGCGTACGGGCGGCACGACTCGCCGCAGCCGAATAATTGCCCATATTGACGCGCAAAAGCCGAAGGAAA
ATCTTCAGGAGAATGCTTAA

Downstream 100 bases:

>100_bases
AGCACGCCAGCAAACTGTGCACCGTTTCCGCCCTGGAGTGCTTGATTTAAAGTGTGAGATCCGGATGCGCGCCTGCGCGC
GCATCCCATCTGTCCTCATC

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MNWITNYVRPKINSMLGRREVPENLWIKCPETGEMVFHRDLEENKWVIPQSGFHMKMPAKARLKDLFDGGIYEAFPQPKV
AQDPLKFRDSKKYSDRLRDSRTKTELEDTIVAGLGQVQGIKLVAVAHEFNFIGGSLGIAAGEAIVKAFERAIAEKCPLVM
FPASGGARMQEGILSLMQLPRTTVAVNMLKEAGLPYIVVLTNPTTGGVTASYAMLGDVHLAEPGAEIGFAGKRVIEQTLR
EKLPEGFQTSEYLMEHGMVDMVVKRHDIPETLARVLNILMKKPAKAIKRDTATELAPLPVAASA

Sequences:

>Translated_304_residues
MNWITNYVRPKINSMLGRREVPENLWIKCPETGEMVFHRDLEENKWVIPQSGFHMKMPAKARLKDLFDGGIYEAFPQPKV
AQDPLKFRDSKKYSDRLRDSRTKTELEDTIVAGLGQVQGIKLVAVAHEFNFIGGSLGIAAGEAIVKAFERAIAEKCPLVM
FPASGGARMQEGILSLMQLPRTTVAVNMLKEAGLPYIVVLTNPTTGGVTASYAMLGDVHLAEPGAEIGFAGKRVIEQTLR
EKLPEGFQTSEYLMEHGMVDMVVKRHDIPETLARVLNILMKKPAKAIKRDTATELAPLPVAASA
>Mature_304_residues
MNWITNYVRPKINSMLGRREVPENLWIKCPETGEMVFHRDLEENKWVIPQSGFHMKMPAKARLKDLFDGGIYEAFPQPKV
AQDPLKFRDSKKYSDRLRDSRTKTELEDTIVAGLGQVQGIKLVAVAHEFNFIGGSLGIAAGEAIVKAFERAIAEKCPLVM
FPASGGARMQEGILSLMQLPRTTVAVNMLKEAGLPYIVVLTNPTTGGVTASYAMLGDVHLAEPGAEIGFAGKRVIEQTLR
EKLPEGFQTSEYLMEHGMVDMVVKRHDIPETLARVLNILMKKPAKAIKRDTATELAPLPVAASA

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA [H

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family [H]

Homologues:

Organism=Escherichia coli, GI1788655, Length=285, Percent_Identity=48.7719298245614, Blast_Score=271, Evalue=3e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 33584; Mature: 33584

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWITNYVRPKINSMLGRREVPENLWIKCPETGEMVFHRDLEENKWVIPQSGFHMKMPAK
CCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEECCCCCCCEECCCCCCEEECCHH
ARLKDLFDGGIYEAFPQPKVAQDPLKFRDSKKYSDRLRDSRTKTELEDTIVAGLGQVQGI
HHHHHHHCCCCHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
KLVAVAHEFNFIGGSLGIAAGEAIVKAFERAIAEKCPLVMFPASGGARMQEGILSLMQLP
EEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHCC
RTTVAVNMLKEAGLPYIVVLTNPTTGGVTASYAMLGDVHLAEPGAEIGFAGKRVIEQTLR
HHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHH
EKLPEGFQTSEYLMEHGMVDMVVKRHDIPETLARVLNILMKKPAKAIKRDTATELAPLPV
HHCCCCCCHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCC
AASA
CCCC
>Mature Secondary Structure
MNWITNYVRPKINSMLGRREVPENLWIKCPETGEMVFHRDLEENKWVIPQSGFHMKMPAK
CCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEECCCCCCCEECCCCCCEEECCHH
ARLKDLFDGGIYEAFPQPKVAQDPLKFRDSKKYSDRLRDSRTKTELEDTIVAGLGQVQGI
HHHHHHHCCCCHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
KLVAVAHEFNFIGGSLGIAAGEAIVKAFERAIAEKCPLVMFPASGGARMQEGILSLMQLP
EEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHCC
RTTVAVNMLKEAGLPYIVVLTNPTTGGVTASYAMLGDVHLAEPGAEIGFAGKRVIEQTLR
HHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHH
EKLPEGFQTSEYLMEHGMVDMVVKRHDIPETLARVLNILMKKPAKAIKRDTATELAPLPV
HHCCCCCCHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCC
AASA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]