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The map label for this gene is hfaC [H]

Identifier: 150398298

GI number: 150398298

Start: 3249478

End: 3251304

Strand: Reverse

Name: hfaC [H]

Synonym: Smed_3104

Alternate gene names: 150398298

Gene position: 3251304-3249478 (Counterclockwise)

Preceding gene: 150398299

Following gene: 150398294

Centisome position: 85.97

GC content: 63.44

Gene sequence:

>1827_bases
TTGGCGCCTCCCATTTTGAAGCTGGACGACATTTTCCTGACCTTCGGCGGCACGCCGCTGCTTGCGGGGGCAGGCCTGCA
GGTGGAGTCCGGCGACCGCATCTGCCTCGTCGGCCGCAACGGCTCGGGCAAGTCGACGCTGATGAAGATCGCTGCCGGGC
TGGCTGAGCCGCAGTCGGGAGAGATATTCAGACATCCCTCCGTGACGATCCGATATCTGCACCAGGCGCCCGATTTCGAG
GGATTCGATACCGTACAGGCCTATGCGGAAGCAGGCCTTGGTCCCGGCGACGATCCTTACCGGGTCGTCTACCTGCTGCA
GCATCTGGGGCTGACCGGCGAGGAGGAGCCGCAGCGCCTTTCCGGAGGTGAGGCGCGGCGTGCCGCGCTCGCTCGCGTGT
TGGCGCCGGAGCCCGACATACTGCTTCTCGACGAGCCGACGAACCATCTCGACCTGCCGACGATCGAGTGGCTGGAAGAC
GAGCTCGTCCGCAGCCGATCGGCACTGGTGCTGATCTCGCACGACCGGCGTTTTCTCGAAAACGTGTCGACGGCGACCGT
CTGGCTCGACAGGGGCCAGTCGCGGCGTCTTGACCGGGGCTTCGCTCATTTCGAGGCATGGCGCGACGAGGTGCTGGAAG
CGGAAGAACTCGAGCAGCACAAACTCGGAAAAGCGATCGAGCGTGAGGAGCACTGGCTGCGCTATGGAGTGACCGCGAGG
CGCAAGCGCAATATGCGCCGGTTGGGTGAGTTGCACGACATGCGGGCTCGCCATCGCGGGCACAAGGGCCCGCAGGGGAC
CGTGCAAGCGACGGCTGCCGATGCCAAGGAGTCCGGCAAGCTCGTCATCGAGGCGGAAAAAATCACCAAGGCTTACGGTG
ACCGCGTGATTGTCGCGCCCTTTTCGATCCGCGTCCATCGCGGCGATCGGATCGGCCTCGTCGGGCCGAACGGCGCCGGC
AAGACGACGCTCCTGAAGCTCCTGACCGGCCAGATCGCGCCGGATAGCGGCAGCATCCGGCTGGGCACCAATCTTGAGAT
CGCGACGCTCGACCAGAAACGCGAAGAGCTGAACCTGGACGAGACCTTGGCGCATTATCTGACCGACGGACGCGGCGAGA
CCCTCCTCGTCAATGGCGAGCAGCGCCATGTCACCGGCTATATGAAGGAATTTCTTTTCCAACCGGAGCAGGCGCGTACG
CCCATTCGCGACCTGTCTGGCGGCGAGCGAGCGCGCCTCATGCTTGCTCGCATCCTGGCGCGTCCCACCAATCTTCTGAT
CCTCGACGAGCCGACCAACGACCTTGACATCGAGACGCTCGACCTTCTGCAAGAAATTGTCGCCGGATTTGCGGGAACCG
TGATCCTCGTCAGTCACGATCGCGATTTCCTCGACCGTACGGTGACATCCACGATCGCACCGGCCAACCCGGAAACGCCC
GATGGCCGCTGGATCGAATATGCCGGCGGCTATTCCGATATGATGGCGCAGCGCCGGGGGGCGCTCGCGGATAAACGCAG
GAGCGAGAAGGGCGGGAAGGCGAAGTCGAGCGATGCCTCGCCCTCGCCGAGCGAGCCTCAGAAAGCGAAGGGCAAGCTTT
CCTACAAGCAGAAATTCGCGCTCGAAAACCTGCCGAAAGAGATTGCCGGCACGGAAGCGAAGATCGCCAGGTGCGAAGAG
AGAATGGCCGATCCGGAGCTTTTCTCGCGCGACCCGAACAGCTTCGCCAAGCTCGCCGCGGAGCTCGATACGTTGAAGAC
GGCCCTGATACGGATGGAAGAGGAGTGGCTCGAACTCGAAATGCTGCGCGAGGAGATCGAGGGCTGA

Upstream 100 bases:

>100_bases
ACCATTTCGAACATCGCGGACGGAACGGTCCGCTTCACCCTGAAATCCGGCCGGGCCGTCATCCTCGCCCGGCCCTATGA
TCTTTCCGGAGCCTGATGCC

Downstream 100 bases:

>100_bases
CCCCGGAATTGCGATATTGCTGAAGGGCAGTACCCTTGCCGCACCCGCGTCTCAACTCCTGGATTCGATCACGTTCATGT
TCTTAAGCCCGGCCCGACCT

Product: ABC transporter-like protein

Products: NA

Alternate protein names: Protein HfaC [H]

Number of amino acids: Translated: 608; Mature: 607

Protein sequence:

>608_residues
MAPPILKLDDIFLTFGGTPLLAGAGLQVESGDRICLVGRNGSGKSTLMKIAAGLAEPQSGEIFRHPSVTIRYLHQAPDFE
GFDTVQAYAEAGLGPGDDPYRVVYLLQHLGLTGEEEPQRLSGGEARRAALARVLAPEPDILLLDEPTNHLDLPTIEWLED
ELVRSRSALVLISHDRRFLENVSTATVWLDRGQSRRLDRGFAHFEAWRDEVLEAEELEQHKLGKAIEREEHWLRYGVTAR
RKRNMRRLGELHDMRARHRGHKGPQGTVQATAADAKESGKLVIEAEKITKAYGDRVIVAPFSIRVHRGDRIGLVGPNGAG
KTTLLKLLTGQIAPDSGSIRLGTNLEIATLDQKREELNLDETLAHYLTDGRGETLLVNGEQRHVTGYMKEFLFQPEQART
PIRDLSGGERARLMLARILARPTNLLILDEPTNDLDIETLDLLQEIVAGFAGTVILVSHDRDFLDRTVTSTIAPANPETP
DGRWIEYAGGYSDMMAQRRGALADKRRSEKGGKAKSSDASPSPSEPQKAKGKLSYKQKFALENLPKEIAGTEAKIARCEE
RMADPELFSRDPNSFAKLAAELDTLKTALIRMEEEWLELEMLREEIEG

Sequences:

>Translated_608_residues
MAPPILKLDDIFLTFGGTPLLAGAGLQVESGDRICLVGRNGSGKSTLMKIAAGLAEPQSGEIFRHPSVTIRYLHQAPDFE
GFDTVQAYAEAGLGPGDDPYRVVYLLQHLGLTGEEEPQRLSGGEARRAALARVLAPEPDILLLDEPTNHLDLPTIEWLED
ELVRSRSALVLISHDRRFLENVSTATVWLDRGQSRRLDRGFAHFEAWRDEVLEAEELEQHKLGKAIEREEHWLRYGVTAR
RKRNMRRLGELHDMRARHRGHKGPQGTVQATAADAKESGKLVIEAEKITKAYGDRVIVAPFSIRVHRGDRIGLVGPNGAG
KTTLLKLLTGQIAPDSGSIRLGTNLEIATLDQKREELNLDETLAHYLTDGRGETLLVNGEQRHVTGYMKEFLFQPEQART
PIRDLSGGERARLMLARILARPTNLLILDEPTNDLDIETLDLLQEIVAGFAGTVILVSHDRDFLDRTVTSTIAPANPETP
DGRWIEYAGGYSDMMAQRRGALADKRRSEKGGKAKSSDASPSPSEPQKAKGKLSYKQKFALENLPKEIAGTEAKIARCEE
RMADPELFSRDPNSFAKLAAELDTLKTALIRMEEEWLELEMLREEIEG
>Mature_607_residues
APPILKLDDIFLTFGGTPLLAGAGLQVESGDRICLVGRNGSGKSTLMKIAAGLAEPQSGEIFRHPSVTIRYLHQAPDFEG
FDTVQAYAEAGLGPGDDPYRVVYLLQHLGLTGEEEPQRLSGGEARRAALARVLAPEPDILLLDEPTNHLDLPTIEWLEDE
LVRSRSALVLISHDRRFLENVSTATVWLDRGQSRRLDRGFAHFEAWRDEVLEAEELEQHKLGKAIEREEHWLRYGVTARR
KRNMRRLGELHDMRARHRGHKGPQGTVQATAADAKESGKLVIEAEKITKAYGDRVIVAPFSIRVHRGDRIGLVGPNGAGK
TTLLKLLTGQIAPDSGSIRLGTNLEIATLDQKREELNLDETLAHYLTDGRGETLLVNGEQRHVTGYMKEFLFQPEQARTP
IRDLSGGERARLMLARILARPTNLLILDEPTNDLDIETLDLLQEIVAGFAGTVILVSHDRDFLDRTVTSTIAPANPETPD
GRWIEYAGGYSDMMAQRRGALADKRRSEKGGKAKSSDASPSPSEPQKAKGKLSYKQKFALENLPKEIAGTEAKIARCEER
MADPELFSRDPNSFAKLAAELDTLKTALIRMEEEWLELEMLREEIEG

Specific function: Involved in attachment of the holdfast to the cell. The holdfast is a structure that allows the bacteria to firmly adhere to surfaces [H]

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=520, Percent_Identity=31.7307692307692, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI10947135, Length=515, Percent_Identity=29.7087378640777, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI69354671, Length=515, Percent_Identity=29.7087378640777, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI10947137, Length=503, Percent_Identity=31.2127236580517, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI27881506, Length=503, Percent_Identity=31.2127236580517, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI9955963, Length=262, Percent_Identity=28.6259541984733, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1787182, Length=638, Percent_Identity=38.7147335423197, Blast_Score=392, Evalue=1e-110,
Organism=Escherichia coli, GI2367384, Length=513, Percent_Identity=32.7485380116959, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1787041, Length=543, Percent_Identity=28.7292817679558, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1789751, Length=629, Percent_Identity=29.8887122416534, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI1788165, Length=191, Percent_Identity=33.5078534031414, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788225, Length=231, Percent_Identity=29.004329004329, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI48994943, Length=590, Percent_Identity=22.8813559322034, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787029, Length=214, Percent_Identity=27.5700934579439, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1786253, Length=217, Percent_Identity=30.4147465437788, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786563, Length=212, Percent_Identity=29.7169811320755, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI87081791, Length=310, Percent_Identity=26.1290322580645, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87081834, Length=192, Percent_Identity=29.6875, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1790739, Length=215, Percent_Identity=29.7674418604651, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786319, Length=154, Percent_Identity=34.4155844155844, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87081709, Length=214, Percent_Identity=25.7009345794392, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI87081782, Length=187, Percent_Identity=34.2245989304813, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789873, Length=203, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787370, Length=198, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787712, Length=198, Percent_Identity=29.2929292929293, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788450, Length=208, Percent_Identity=30.7692307692308, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1789032, Length=178, Percent_Identity=29.2134831460674, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1786803, Length=209, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1787112, Length=197, Percent_Identity=32.994923857868, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1788761, Length=230, Percent_Identity=28.695652173913, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787164, Length=214, Percent_Identity=30.8411214953271, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI145693107, Length=205, Percent_Identity=30.7317073170732, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786398, Length=218, Percent_Identity=27.5229357798165, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787758, Length=205, Percent_Identity=27.8048780487805, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790467, Length=192, Percent_Identity=25.5208333333333, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17555318, Length=495, Percent_Identity=29.8989898989899, Blast_Score=171, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI17559834, Length=554, Percent_Identity=27.7978339350181, Blast_Score=168, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI17553372, Length=527, Percent_Identity=29.2220113851992, Blast_Score=149, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6320874, Length=529, Percent_Identity=27.2211720226843, Blast_Score=170, Evalue=8e-43,
Organism=Saccharomyces cerevisiae, GI6321121, Length=386, Percent_Identity=30.0518134715026, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6324314, Length=366, Percent_Identity=27.5956284153005, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6325030, Length=355, Percent_Identity=27.887323943662, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6323278, Length=366, Percent_Identity=27.3224043715847, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24642252, Length=554, Percent_Identity=30.14440433213, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI18859989, Length=554, Percent_Identity=30.14440433213, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24641342, Length=519, Percent_Identity=28.5163776493256, Blast_Score=179, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24666836, Length=511, Percent_Identity=30.5283757338552, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI221500365, Length=168, Percent_Identity=33.9285714285714, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI116007184, Length=198, Percent_Identity=32.3232323232323, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR007406 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 67548; Mature: 67416

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPPILKLDDIFLTFGGTPLLAGAGLQVESGDRICLVGRNGSGKSTLMKIAAGLAEPQSG
CCCCCEEECCEEEEECCCCEEECCCEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCCCC
EIFRHPSVTIRYLHQAPDFEGFDTVQAYAEAGLGPGDDPYRVVYLLQHLGLTGEEEPQRL
CEEECCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCHHC
SGGEARRAALARVLAPEPDILLLDEPTNHLDLPTIEWLEDELVRSRSALVLISHDRRFLE
CCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHH
NVSTATVWLDRGQSRRLDRGFAHFEAWRDEVLEAEELEQHKLGKAIEREEHWLRYGVTAR
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHH
RKRNMRRLGELHDMRARHRGHKGPQGTVQATAADAKESGKLVIEAEKITKAYGDRVIVAP
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCEEEEHHHHHHHHCCEEEEEE
FSIRVHRGDRIGLVGPNGAGKTTLLKLLTGQIAPDSGSIRLGTNLEIATLDQKREELNLD
EEEEEECCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEECCCEEEEECCHHHHHCCHH
ETLAHYLTDGRGETLLVNGEQRHVTGYMKEFLFQPEQARTPIRDLSGGERARLMLARILA
HHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCHHHCCCHHHCCCCHHHHHHHHHHHC
RPTNLLILDEPTNDLDIETLDLLQEIVAGFAGTVILVSHDRDFLDRTVTSTIAPANPETP
CCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCC
DGRWIEYAGGYSDMMAQRRGALADKRRSEKGGKAKSSDASPSPSEPQKAKGKLSYKQKFA
CCCEEEECCCHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHH
LENLPKEIAGTEAKIARCEERMADPELFSRDPNSFAKLAAELDTLKTALIRMEEEWLELE
HHHCCHHHCCCHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLREEIEG
HHHHHHCC
>Mature Secondary Structure 
APPILKLDDIFLTFGGTPLLAGAGLQVESGDRICLVGRNGSGKSTLMKIAAGLAEPQSG
CCCCEEECCEEEEECCCCEEECCCEEECCCCEEEEEECCCCCHHHHHHHHHHCCCCCCC
EIFRHPSVTIRYLHQAPDFEGFDTVQAYAEAGLGPGDDPYRVVYLLQHLGLTGEEEPQRL
CEEECCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCHHC
SGGEARRAALARVLAPEPDILLLDEPTNHLDLPTIEWLEDELVRSRSALVLISHDRRFLE
CCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHH
NVSTATVWLDRGQSRRLDRGFAHFEAWRDEVLEAEELEQHKLGKAIEREEHWLRYGVTAR
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHH
RKRNMRRLGELHDMRARHRGHKGPQGTVQATAADAKESGKLVIEAEKITKAYGDRVIVAP
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCEEEEHHHHHHHHCCEEEEEE
FSIRVHRGDRIGLVGPNGAGKTTLLKLLTGQIAPDSGSIRLGTNLEIATLDQKREELNLD
EEEEEECCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCEEECCCEEEEECCHHHHHCCHH
ETLAHYLTDGRGETLLVNGEQRHVTGYMKEFLFQPEQARTPIRDLSGGERARLMLARILA
HHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCHHHCCCHHHCCCCHHHHHHHHHHHC
RPTNLLILDEPTNDLDIETLDLLQEIVAGFAGTVILVSHDRDFLDRTVTSTIAPANPETP
CCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCC
DGRWIEYAGGYSDMMAQRRGALADKRRSEKGGKAKSSDASPSPSEPQKAKGKLSYKQKFA
CCCEEEECCCHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHH
LENLPKEIAGTEAKIARCEERMADPELFSRDPNSFAKLAAELDTLKTALIRMEEEWLELE
HHHCCHHHCCCHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLREEIEG
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11259647; 8150261 [H]