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The map label for this gene is rpoB [H]

Identifier: 150396199

GI number: 150396199

Start: 1053840

End: 1057982

Strand: Direct

Name: rpoB [H]

Synonym: Smed_0978

Alternate gene names: 150396199

Gene position: 1053840-1057982 (Clockwise)

Preceding gene: 150396198

Following gene: 150396200

Centisome position: 27.87

GC content: 60.51

Gene sequence:

>4143_bases
ATGGCTCAGACCCTTTCGTTTAACGGTCGTAGGCGCGTACGCAAGTTTTTTGGTAAAATTCCCGAAGTCGCGGAGATGCC
GAACCTCATCGAGGTTCAGAAGGCATCCTACGACCAGTTCCTCATGGTGGACGAGCCCCAAGGCGGGCGGCCGGACGAGG
GGCTTCAAGCCGTTTTCAAATCGGTGTTTCCGATAAAGGATTTCTCCGGCGCTTCGATGCTCGAATTCGTTTCCTACGAA
TTCGAGGCACCCAAGTTCGACGTCGAGGAGTGCCGTCAGCGCGACCTGACCTATGCGGCGCCTCTCAAGGTCACGTTGCG
CCTGATCGTGTTCGATATCGACGAGGACACCGGCGCCAAGTCCATCAAGGACATCAAGGAACAGAACGTCTACATGGGCG
ACATGCCGCTCATGACGGACAACGGAACCTTCATCGTCAACGGCACCGAGCGCGTCATCGTCTCGCAGATGCACCGTTCG
CCAGGTGTCTTTTTCGATCATGACAAGGGCAAGAGCCACTCGTCCGGCAAACTGCTCTTTGCCGCCCGCGTGATCCCCTA
TCGTGGTTCGTGGCTCGATATCGAATTCGATGCGAAGGACATCGTCCATGCGCGCATCGACCGCCGCCGCAAGATCCCGG
TGACGTCGCTTCTGATGGCGCTCGGAATGGACGGCGAAGAGATTCTCGACACCTTCTATACGAAGTCGCTCTACCAGCGC
GACGGCGAGGGCTGGCGCGTTCCGTTCCAGCCTGACGCGCTCAAGGGCCAGAAGGCCTTGGCAGACCTGATCGACGCCGA
TACCGGCGAAGTGGTCGTCGAAGGCGGCAAGAAGCTGACGCCGCGCCTGCTTCGTCAGTTGCAGGACAAGGGCCTGAAGG
CCCTCAAGGCGACTGATGATGATCTTTACGGCAACTACCTCGCCGAGGATGTGGTCAACTTCGAGACAGGTGAAATCTAC
CTGGAAGCCGGCGACGAAATCGACGAGAAGACGCTTCCGGTCATCCTTTCCGCCGGGTTCGACGAGATCCCGGTTCTCGA
CATAGACCACATCAATATCGGCGCCTATATCCGCAATACGCTTGCGGCCGACAAGAACGAAAACCGACAGGACGCGCTGT
TCGATATCTACCGCGTCATGCGTCCGGGTGAGCCGCCGACGATGGATTCGGCCGAAGCCATGTTCAATGCGCTCTTCTTC
GATGCCGAGCGCTACGACCTTTCGGCCGTCGGCCGCGTCAAGATGAACATGCGTCTTGATCTGGATGTTCCGGATACGGT
TCGCACGCTGCGCAAGGAAGATATCCTGGCCGTCGTCAAGATGCTCGTCGAACTGCGTGACGGCAAGGGCGAGATCGACG
ACATCGACAACCTCGGCAACCGCCGCGTCCGGTCGGTGGGCGAGTTGATGGAGAACCAGTATCGGCTGGGTCTGCTGCGC
ATGGAACGTGCGATCAAGGAGCGCATGTCCTCGATCGAGATCGACACAGTGATGCCGCAAGACCTCATCAACGCGAAGCC
GGCTGCCGCCGCGGTGCGTGAATTCTTCGGCTCGTCTCAGCTTTCGCAGTTCATGGACCAGGTGAACCCGCTCTCGGAAA
TCACCCACAAGCGCCGCCTTTCGGCACTGGGTCCTGGCGGTCTTACCCGTGAACGCGCCGGCTTCGAAGTTCGCGACGTG
CATCCGACGCATTATGGCCGTATCTGCCCGATCGAAACGCCGGAAGGCCCGAACATCGGTCTGATCAACTCGCTTGCGAC
ATTTGCCCGCGTCAACAAGTATGGCTTCATCGAAAGCCCTTACCGTAAGATCGTCGACGGCAAGGTGACCAGCGACGTCG
TCTATCTCTCGGCGATGGAAGAAGCCAAGTATCACGTTGCGCAAGCGAACTCGGTGCTGGACGAAGACGGCTCCTTCTCG
GAAGAGTTCGTCGTTTGCCGCCACGCCGGCGAAGTCATGCTGGCGCCGCGCGACAATATCAACCTGATGGACGTTTCGCC
GAAGCAGCTCGTCTCCGTCGCGGCCGCGCTCATTCCGTTCCTCGAGAACGATGACGCCAACCGCGCGCTGATGGGTTCGA
ACATGCAGCGTCAGGCCGTGCCGTTGCTGCGTGCGGAGGCACCCTTCGTCGGCACAGGCATGGAGCCGGTCGTCGCGCGT
GACTCCGGTGCTGCTATCGCTGCGCGCCGCGGCGGTATCGTGGATCAGGTAGACGCGACGCGTATCGTTATCCGCGCCAC
CGAGGACCTGGATCCGTCCAAGTCCGGCGTCGATATCTACCGCCTGCAGAAGTTCCAGCGCTCCAACCAGAACACCTGCG
TCAACCAGCGCCCGCTGGTCACCGTCGGTGACGTTCTGAACAAGGGCGACATCATCGCGGATGGTCCGTCTACGGACCTC
GGCGATCTGGCGCTCGGCCGCAACGCGCTCGTCGCGTTCATGCCCTGGAACGGCTACAACTACGAAGATTCGATCCTGCT
TTCCGAGCGGATCGTGCGCGATGACGTCTTCACGTCCATCCACATCGAAGAATTCGAGGTGATGGCGCGTGATACCAAGC
TTGGTCCGGAAGAAATCACCCGTGACATTCCGAACGTTTCGGAAGAAGCGCTGAAGAACCTCGACGAAGCCGGCATCGTC
TATATCGGCGCCGAAGTTCAGCCGGGCGACATTCTCGTAGGCAAGATCACGCCGAAGGGCGAAAGCCCAATGACGCCGGA
AGAAAAGCTTCTGCGCGCCATCTTCGGTGAGAAGGCGTCGGATGTTCGTGATACCTCCATGCGCATGCCTCCGGGCACGT
TCGGTACGGTCGTCGAAGTTCGCGTCTTCAATCGTCATGGCGTGGAGAAAGACGAGCGCGCGATGGCCATCGAGCGCGAG
GAAATCGAACGCCTCGCCAAGGACCGCGACGACGAACAGGCGATCCTGGATCGTAACGTCTATGCGCGTCTGGTCGACAT
GTTGCGCGGTCACGTGGCGGTTGCCGGTCCGAAGGGCTTTAAGAAGGGCACCGAGCTTTCGAATGCCGTGATCAGCGAAT
ATCCCCGCTCGCAGTGGTGGATGTTCGCCATCGAGGACGAAAAGGCGCAGGGCGAGATCGAAGCGCTCCGCGGTCAGTAC
GACGAATCCAAGTCGCGTCTTGAACAGCGCTTCATGGACAAGGTCGAGAAGGTCCAGCGTGGCGACGAAATGCCTCCTGG
CGTCATGAAGATGGTCAAGGTCTTCGTCGCTGTGAAGCGCAAGATCCAGCCGGGCGACAAGATGGCCGGCCGTCACGGCA
ACAAGGGTGTCGTGTCGCGCATCGTGCCGATCGAAGACATGCCGTTCCTGGAGGACGGCACGCATGTCGACGTGGTGCTG
AACCCGCTCGGCGTGCCTTCGCGCATGAATGTCGGCCAGATTCTCGAGACCCATCTCGGCTGGGCTTGCGCCGGCATGGG
CAAGAAGATCGGAGCGATGCTCGATGCGTATAAGGCGGGCGCTGACATTCAGCCGCTGCGCGACACCATCGACAGCGTCA
TCGGATCCGGTCCGAAGGGCGAGCCGATCAAGCAGTACGACGATGAGTCGATCGTACGGCTGGCCGAGCAGACCCGTCGC
GGCGTATCGATCGCAACGCCGGTCTTCGACGGTGCAGTCGAGGCCGACGTCAACGAGATGCTCGAGCAGGCCGGCCTCAA
GGTAACCGGCCAGTCGACGCTCTATGACGGCCGTACCGGCGAGACGTTCGACCGTCAGGTGACCGTGGGCTACATCTACA
TGCTGAAGCTCAACCACCTGGTCGACGACAAGATCCACGCCCGTTCGATCGGACCGTATTCGCTCGTTACCCAGCAGCCG
CTGGGCGGCAAGGCGCAGTTCGGCGGTCAGCGCTTCGGCGAGATGGAGGTCTGGGCGCTGGAAGCCTATGGCGCCGCCTA
CACGCTGCAGGAGATGCTGACGGTCAAGTCGGATGACGTGGCCGGCCGCACCAAGGTCTATGAAGCTATCGTCCGTGGCG
ACGACACCTTCGAAGCGGGCATTCCGGAGAGCTTCAACGTTCTCGTCAAGGAAATGCGCTCGCTGGGCCTTTCGGTCGAG
CTGGAAAACTCCAAGGTCGACGAAGTCGGTGCCAGTGCGCAGCTGCCTGACGCGGCCGAATAA

Upstream 100 bases:

>100_bases
AAAGCTGGACGAGATTGAACCACCCATTGATTGACGGGGCCGACTGGCCATCGGTTCCCGTCCGTTGCAGGCCCGGATGC
AAGATTGACAAGGAGCGACG

Downstream 100 bases:

>100_bases
GAGACATGAGGTGCGTGCCGCTCAGCGGCGCGCACCGTTTCCGCCGTCGGGCATCTGATTGTCCGCGGCAGGAACAGGGG
CCGCACCCGATGCGGTTTTA

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1380; Mature: 1379

Protein sequence:

>1380_residues
MAQTLSFNGRRRVRKFFGKIPEVAEMPNLIEVQKASYDQFLMVDEPQGGRPDEGLQAVFKSVFPIKDFSGASMLEFVSYE
FEAPKFDVEECRQRDLTYAAPLKVTLRLIVFDIDEDTGAKSIKDIKEQNVYMGDMPLMTDNGTFIVNGTERVIVSQMHRS
PGVFFDHDKGKSHSSGKLLFAARVIPYRGSWLDIEFDAKDIVHARIDRRRKIPVTSLLMALGMDGEEILDTFYTKSLYQR
DGEGWRVPFQPDALKGQKALADLIDADTGEVVVEGGKKLTPRLLRQLQDKGLKALKATDDDLYGNYLAEDVVNFETGEIY
LEAGDEIDEKTLPVILSAGFDEIPVLDIDHINIGAYIRNTLAADKNENRQDALFDIYRVMRPGEPPTMDSAEAMFNALFF
DAERYDLSAVGRVKMNMRLDLDVPDTVRTLRKEDILAVVKMLVELRDGKGEIDDIDNLGNRRVRSVGELMENQYRLGLLR
MERAIKERMSSIEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQVNPLSEITHKRRLSALGPGGLTRERAGFEVRDV
HPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIESPYRKIVDGKVTSDVVYLSAMEEAKYHVAQANSVLDEDGSFS
EEFVVCRHAGEVMLAPRDNINLMDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLLRAEAPFVGTGMEPVVAR
DSGAAIAARRGGIVDQVDATRIVIRATEDLDPSKSGVDIYRLQKFQRSNQNTCVNQRPLVTVGDVLNKGDIIADGPSTDL
GDLALGRNALVAFMPWNGYNYEDSILLSERIVRDDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVSEEALKNLDEAGIV
YIGAEVQPGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSMRMPPGTFGTVVEVRVFNRHGVEKDERAMAIERE
EIERLAKDRDDEQAILDRNVYARLVDMLRGHVAVAGPKGFKKGTELSNAVISEYPRSQWWMFAIEDEKAQGEIEALRGQY
DESKSRLEQRFMDKVEKVQRGDEMPPGVMKMVKVFVAVKRKIQPGDKMAGRHGNKGVVSRIVPIEDMPFLEDGTHVDVVL
NPLGVPSRMNVGQILETHLGWACAGMGKKIGAMLDAYKAGADIQPLRDTIDSVIGSGPKGEPIKQYDDESIVRLAEQTRR
GVSIATPVFDGAVEADVNEMLEQAGLKVTGQSTLYDGRTGETFDRQVTVGYIYMLKLNHLVDDKIHARSIGPYSLVTQQP
LGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLGLSVE
LENSKVDEVGASAQLPDAAE

Sequences:

>Translated_1380_residues
MAQTLSFNGRRRVRKFFGKIPEVAEMPNLIEVQKASYDQFLMVDEPQGGRPDEGLQAVFKSVFPIKDFSGASMLEFVSYE
FEAPKFDVEECRQRDLTYAAPLKVTLRLIVFDIDEDTGAKSIKDIKEQNVYMGDMPLMTDNGTFIVNGTERVIVSQMHRS
PGVFFDHDKGKSHSSGKLLFAARVIPYRGSWLDIEFDAKDIVHARIDRRRKIPVTSLLMALGMDGEEILDTFYTKSLYQR
DGEGWRVPFQPDALKGQKALADLIDADTGEVVVEGGKKLTPRLLRQLQDKGLKALKATDDDLYGNYLAEDVVNFETGEIY
LEAGDEIDEKTLPVILSAGFDEIPVLDIDHINIGAYIRNTLAADKNENRQDALFDIYRVMRPGEPPTMDSAEAMFNALFF
DAERYDLSAVGRVKMNMRLDLDVPDTVRTLRKEDILAVVKMLVELRDGKGEIDDIDNLGNRRVRSVGELMENQYRLGLLR
MERAIKERMSSIEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQVNPLSEITHKRRLSALGPGGLTRERAGFEVRDV
HPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIESPYRKIVDGKVTSDVVYLSAMEEAKYHVAQANSVLDEDGSFS
EEFVVCRHAGEVMLAPRDNINLMDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLLRAEAPFVGTGMEPVVAR
DSGAAIAARRGGIVDQVDATRIVIRATEDLDPSKSGVDIYRLQKFQRSNQNTCVNQRPLVTVGDVLNKGDIIADGPSTDL
GDLALGRNALVAFMPWNGYNYEDSILLSERIVRDDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVSEEALKNLDEAGIV
YIGAEVQPGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSMRMPPGTFGTVVEVRVFNRHGVEKDERAMAIERE
EIERLAKDRDDEQAILDRNVYARLVDMLRGHVAVAGPKGFKKGTELSNAVISEYPRSQWWMFAIEDEKAQGEIEALRGQY
DESKSRLEQRFMDKVEKVQRGDEMPPGVMKMVKVFVAVKRKIQPGDKMAGRHGNKGVVSRIVPIEDMPFLEDGTHVDVVL
NPLGVPSRMNVGQILETHLGWACAGMGKKIGAMLDAYKAGADIQPLRDTIDSVIGSGPKGEPIKQYDDESIVRLAEQTRR
GVSIATPVFDGAVEADVNEMLEQAGLKVTGQSTLYDGRTGETFDRQVTVGYIYMLKLNHLVDDKIHARSIGPYSLVTQQP
LGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLGLSVE
LENSKVDEVGASAQLPDAAE
>Mature_1379_residues
AQTLSFNGRRRVRKFFGKIPEVAEMPNLIEVQKASYDQFLMVDEPQGGRPDEGLQAVFKSVFPIKDFSGASMLEFVSYEF
EAPKFDVEECRQRDLTYAAPLKVTLRLIVFDIDEDTGAKSIKDIKEQNVYMGDMPLMTDNGTFIVNGTERVIVSQMHRSP
GVFFDHDKGKSHSSGKLLFAARVIPYRGSWLDIEFDAKDIVHARIDRRRKIPVTSLLMALGMDGEEILDTFYTKSLYQRD
GEGWRVPFQPDALKGQKALADLIDADTGEVVVEGGKKLTPRLLRQLQDKGLKALKATDDDLYGNYLAEDVVNFETGEIYL
EAGDEIDEKTLPVILSAGFDEIPVLDIDHINIGAYIRNTLAADKNENRQDALFDIYRVMRPGEPPTMDSAEAMFNALFFD
AERYDLSAVGRVKMNMRLDLDVPDTVRTLRKEDILAVVKMLVELRDGKGEIDDIDNLGNRRVRSVGELMENQYRLGLLRM
ERAIKERMSSIEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQVNPLSEITHKRRLSALGPGGLTRERAGFEVRDVH
PTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIESPYRKIVDGKVTSDVVYLSAMEEAKYHVAQANSVLDEDGSFSE
EFVVCRHAGEVMLAPRDNINLMDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLLRAEAPFVGTGMEPVVARD
SGAAIAARRGGIVDQVDATRIVIRATEDLDPSKSGVDIYRLQKFQRSNQNTCVNQRPLVTVGDVLNKGDIIADGPSTDLG
DLALGRNALVAFMPWNGYNYEDSILLSERIVRDDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVSEEALKNLDEAGIVY
IGAEVQPGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSMRMPPGTFGTVVEVRVFNRHGVEKDERAMAIEREE
IERLAKDRDDEQAILDRNVYARLVDMLRGHVAVAGPKGFKKGTELSNAVISEYPRSQWWMFAIEDEKAQGEIEALRGQYD
ESKSRLEQRFMDKVEKVQRGDEMPPGVMKMVKVFVAVKRKIQPGDKMAGRHGNKGVVSRIVPIEDMPFLEDGTHVDVVLN
PLGVPSRMNVGQILETHLGWACAGMGKKIGAMLDAYKAGADIQPLRDTIDSVIGSGPKGEPIKQYDDESIVRLAEQTRRG
VSIATPVFDGAVEADVNEMLEQAGLKVTGQSTLYDGRTGETFDRQVTVGYIYMLKLNHLVDDKIHARSIGPYSLVTQQPL
GGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLGLSVEL
ENSKVDEVGASAQLPDAAE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI238908503, Length=308, Percent_Identity=31.1688311688312, Blast_Score=133, Evalue=1e-30,
Organism=Homo sapiens, GI238908505, Length=308, Percent_Identity=31.1688311688312, Blast_Score=133, Evalue=1e-30,
Organism=Homo sapiens, GI4505941, Length=249, Percent_Identity=32.1285140562249, Blast_Score=124, Evalue=6e-28,
Organism=Homo sapiens, GI33469941, Length=322, Percent_Identity=28.8819875776398, Blast_Score=119, Evalue=2e-26,
Organism=Homo sapiens, GI212286172, Length=322, Percent_Identity=28.8819875776398, Blast_Score=119, Evalue=3e-26,
Organism=Escherichia coli, GI1790419, Length=1362, Percent_Identity=58.8105726872247, Blast_Score=1623, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25144348, Length=308, Percent_Identity=29.8701298701299, Blast_Score=124, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17552304, Length=308, Percent_Identity=29.5454545454545, Blast_Score=123, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17506623, Length=238, Percent_Identity=31.5126050420168, Blast_Score=122, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6324725, Length=310, Percent_Identity=29.6774193548387, Blast_Score=132, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6324781, Length=301, Percent_Identity=29.2358803986711, Blast_Score=124, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6325267, Length=250, Percent_Identity=32, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17647877, Length=248, Percent_Identity=31.4516129032258, Blast_Score=124, Evalue=4e-28,
Organism=Drosophila melanogaster, GI17136444, Length=249, Percent_Identity=32.1285140562249, Blast_Score=122, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17136446, Length=249, Percent_Identity=32.5301204819277, Blast_Score=112, Evalue=1e-24,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 153341; Mature: 153209

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQTLSFNGRRRVRKFFGKIPEVAEMPNLIEVQKASYDQFLMVDEPQGGRPDEGLQAVFK
CCCCCCCCCHHHHHHHHCCCCCHHHCCCCCHHHHCCCCCEEEEECCCCCCCCHHHHHHHH
SVFPIKDFSGASMLEFVSYEFEAPKFDVEECRQRDLTYAAPLKVTLRLIVFDIDEDTGAK
HHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCEECCCEEEEEEEEEEECCCCCHH
SIKDIKEQNVYMGDMPLMTDNGTFIVNGTERVIVSQMHRSPGVFFDHDKGKSHSSGKLLF
HHHHHHHCCEEECCCCEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCCEEE
AARVIPYRGSWLDIEFDAKDIVHARIDRRRKIPVTSLLMALGMDGEEILDTFYTKSLYQR
EEEEECCCCCEEEEEECHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHC
DGEGWRVPFQPDALKGQKALADLIDADTGEVVVEGGKKLTPRLLRQLQDKGLKALKATDD
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHCCCHHHHCCCC
DLYGNYLAEDVVNFETGEIYLEAGDEIDEKTLPVILSAGFDEIPVLDIDHINIGAYIRNT
HHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEECCCCCCCEEECCCCCHHHHHHHH
LAADKNENRQDALFDIYRVMRPGEPPTMDSAEAMFNALFFDAERYDLSAVGRVKMNMRLD
HHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHEECEEEEEEEEE
LDVPDTVRTLRKEDILAVVKMLVELRDGKGEIDDIDNLGNRRVRSVGELMENQYRLGLLR
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHH
MERAIKERMSSIEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQVNPLSEITHKRRL
HHHHHHHHHHCCEEHHCCCHHHHCCCHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHH
SALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIESP
HHCCCCCCCHHHCCCEEEECCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
YRKIVDGKVTSDVVYLSAMEEAKYHVAQANSVLDEDGSFSEEFVVCRHAGEVMLAPRDNI
HHHHHCCCHHHHEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEECCCCEEECCCCCC
NLMDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLLRAEAPFVGTGMEPVVAR
EEEECCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHCHHHHCCCCCCCCCCCCEEEC
DSGAAIAARRGGIVDQVDATRIVIRATEDLDPSKSGVDIYRLQKFQRSNQNTCVNQRPLV
CCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCE
TVGDVLNKGDIIADGPSTDLGDLALGRNALVAFMPWNGYNYEDSILLSERIVRDDVFTSI
EHHHHCCCCCEEECCCCCCHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHEE
HIEEFEVMARDTKLGPEEITRDIPNVSEEALKNLDEAGIVYIGAEVQPGDILVGKITPKG
EHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCC
ESPMTPEEKLLRAIFGEKASDVRDTSMRMPPGTFGTVVEVRVFNRHGVEKDERAMAIERE
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHH
EIERLAKDRDDEQAILDRNVYARLVDMLRGHVAVAGPKGFKKGTELSNAVISEYPRSQWW
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHCCCCCEE
MFAIEDEKAQGEIEALRGQYDESKSRLEQRFMDKVEKVQRGDEMPPGVMKMVKVFVAVKR
EEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
KIQPGDKMAGRHGNKGVVSRIVPIEDMPFLEDGTHVDVVLNPLGVPSRMNVGQILETHLG
HCCCCHHHCCCCCCCCHHHEECCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHC
WACAGMGKKIGAMLDAYKAGADIQPLRDTIDSVIGSGPKGEPIKQYDDESIVRLAEQTRR
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHCCHHHHHHHHHHHHC
GVSIATPVFDGAVEADVNEMLEQAGLKVTGQSTLYDGRTGETFDRQVTVGYIYMLKLNHL
CCEEECHHHCCCHHHHHHHHHHHCCCEEECCCEEECCCCCCCCCCEEEEEEEEEEEHHHH
VDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDV
HCCCHHHCCCCCHHHEECCCCCCCCCCCCCCCCCEEEEEEEHHCHHHHHHHHHHHCCCCC
AGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLGLSVELENSKVDEVGASAQLPDAAE
CCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCHHHCCCCCCCCCCCC
>Mature Secondary Structure 
AQTLSFNGRRRVRKFFGKIPEVAEMPNLIEVQKASYDQFLMVDEPQGGRPDEGLQAVFK
CCCCCCCCHHHHHHHHCCCCCHHHCCCCCHHHHCCCCCEEEEECCCCCCCCHHHHHHHH
SVFPIKDFSGASMLEFVSYEFEAPKFDVEECRQRDLTYAAPLKVTLRLIVFDIDEDTGAK
HHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCEECCCEEEEEEEEEEECCCCCHH
SIKDIKEQNVYMGDMPLMTDNGTFIVNGTERVIVSQMHRSPGVFFDHDKGKSHSSGKLLF
HHHHHHHCCEEECCCCEEECCCEEEECCCHHHHHHHHHCCCCCEEECCCCCCCCCCCEEE
AARVIPYRGSWLDIEFDAKDIVHARIDRRRKIPVTSLLMALGMDGEEILDTFYTKSLYQR
EEEEECCCCCEEEEEECHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHC
DGEGWRVPFQPDALKGQKALADLIDADTGEVVVEGGKKLTPRLLRQLQDKGLKALKATDD
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHCCCHHHHCCCC
DLYGNYLAEDVVNFETGEIYLEAGDEIDEKTLPVILSAGFDEIPVLDIDHINIGAYIRNT
HHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEEECCCCCCCEEECCCCCHHHHHHHH
LAADKNENRQDALFDIYRVMRPGEPPTMDSAEAMFNALFFDAERYDLSAVGRVKMNMRLD
HHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCHHEECEEEEEEEEE
LDVPDTVRTLRKEDILAVVKMLVELRDGKGEIDDIDNLGNRRVRSVGELMENQYRLGLLR
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHH
MERAIKERMSSIEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQVNPLSEITHKRRL
HHHHHHHHHHCCEEHHCCCHHHHCCCHHHHHHHHHHCHHHHHHHHHHCCHHHHHHHHHHH
SALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIESP
HHCCCCCCCHHHCCCEEEECCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
YRKIVDGKVTSDVVYLSAMEEAKYHVAQANSVLDEDGSFSEEFVVCRHAGEVMLAPRDNI
HHHHHCCCHHHHEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEECCCCEEECCCCCC
NLMDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLLRAEAPFVGTGMEPVVAR
EEEECCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHCHHHHCCCCCCCCCCCCEEEC
DSGAAIAARRGGIVDQVDATRIVIRATEDLDPSKSGVDIYRLQKFQRSNQNTCVNQRPLV
CCCCEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCE
TVGDVLNKGDIIADGPSTDLGDLALGRNALVAFMPWNGYNYEDSILLSERIVRDDVFTSI
EHHHHCCCCCEEECCCCCCHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHEE
HIEEFEVMARDTKLGPEEITRDIPNVSEEALKNLDEAGIVYIGAEVQPGDILVGKITPKG
EHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHCCCCCCEEEEECCCCCCCEEEEEECCCC
ESPMTPEEKLLRAIFGEKASDVRDTSMRMPPGTFGTVVEVRVFNRHGVEKDERAMAIERE
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHH
EIERLAKDRDDEQAILDRNVYARLVDMLRGHVAVAGPKGFKKGTELSNAVISEYPRSQWW
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHCCCCCEE
MFAIEDEKAQGEIEALRGQYDESKSRLEQRFMDKVEKVQRGDEMPPGVMKMVKVFVAVKR
EEEEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
KIQPGDKMAGRHGNKGVVSRIVPIEDMPFLEDGTHVDVVLNPLGVPSRMNVGQILETHLG
HCCCCHHHCCCCCCCCHHHEECCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHC
WACAGMGKKIGAMLDAYKAGADIQPLRDTIDSVIGSGPKGEPIKQYDDESIVRLAEQTRR
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHCCHHHHHHHHHHHHC
GVSIATPVFDGAVEADVNEMLEQAGLKVTGQSTLYDGRTGETFDRQVTVGYIYMLKLNHL
CCEEECHHHCCCHHHHHHHHHHHCCCEEECCCEEECCCCCCCCCCEEEEEEEEEEEHHHH
VDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDV
HCCCHHHCCCCCHHHEECCCCCCCCCCCCCCCCCEEEEEEEHHCHHHHHHHHHHHCCCCC
AGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLGLSVELENSKVDEVGASAQLPDAAE
CCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA