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The map label for this gene is yccK [H]

Identifier: 150396066

GI number: 150396066

Start: 900347

End: 901519

Strand: Direct

Name: yccK [H]

Synonym: Smed_0842

Alternate gene names: 150396066

Gene position: 900347-901519 (Clockwise)

Preceding gene: 150396065

Following gene: 150396067

Centisome position: 23.81

GC content: 62.06

Gene sequence:

>1173_bases
ATGACTGATCGACCTGGAAACGACGTTTCCGCGCGTTACGCTACAATGACCAATCGTCGCACATTGCTTGGCGCCGGTCT
CGGCCTCGCAGCAGCGTCTCTTGTGAGCACCACTAGCGCCAGTGCGCAGTCCGAAACCAGCAACCGTTCAGACGCCACCC
CCATCACCCTGCAGCAGGGGAAATCAATGGGCGTTCGCAAACTCGGCTCATTGGAAGTTTCTGCCATCGGTCTCGGATGC
CTCGACATGGTCGGTTATTATGGCGGCGGCCCACGAGACCGTAAGTCCATGGTCTCGCTGATACGCGCGGCCTTCGAGCA
AGGTGTGACATTCTTCGACACCGCAGAGGTCTACGGGCCTTACATCAGCGAGGAATATGTCGCCGAGGCGCTCGCGCCGG
TGCGCGATCAGGTCGTCATCGCCACGAAATTCGGCTTTGGTGTCGAGGAGGGCCAGCCGACGGCGCTGAACAGCCAGCCC
GATCATCTGCGCCGGGCGGTCGACGGCTCCCTCAAGCGTCTGAAGACTGACCATATCGATCTTCTGTATCAGCATCGTCC
CGACCCGAATGTGCCGATCGAAGACGTCGCGGAGGCTGTCAAAGACCTGATTCAGGCCGGAAAGGTCAAGCATTGGGGGC
TTTCCGAGGCCAGCGCGGGCACCATCCGCCGGGCTCACGCCGTTCACCCAGTCTCCGCGGTGCAAAGCGAATATGCGATG
TGGTGGCGCGAACCCGAGACGCGGATCTTCCCGACGCTGGAGGAACTCGGAATCGGCTTTGTGCCCTATTGCCCACTCGG
GCGGAGTTTTCTTGCGGGCGCGGTCAACCCCAGCCAGCGTTTTGAGCGAACCGATCGCCGGCACAACCTGCCGCGCTTCA
CGCCCGAGGCGCTGGCCGCCAACATGGCCCTGTTCGACTATGTCCGCGACTGGGCACAGCGCAAAAAAACGACGCCTGCG
CAGTTTGCGTTAGCATGGATCCTGGCGCAGCGGCCGTGGATCGCCCCGATTCCGGGCACAACCCAGTACCCGCATCTTGC
GGAAAACCTCGGCGCGACGGGTGTCCAACTGACGGCTGACGAACTTCGCGAGATCGACGCCGGGCTCGCTCGCATCAAGC
TGCAAGGTGGTCGGGCCGATCCCTTCACCGAGAGCCAGTTCGACTACAGCTAA

Upstream 100 bases:

>100_bases
GGAAAGGTGATCTCAAGGCGTGTCATCGAGACCAACCCGAAAATGGTTGGCTCCAAACAGTTTGCTTGGACTGAGCAGTA
AAAATGCGGGTGAGATAGTG

Downstream 100 bases:

>100_bases
GAGGTCTCCTCCCGCTCGTATTTGAACACCTGATTGCCCTCTCGACAACCAGCCACGAATTCCAGGAGACCCCGATGAAA
CGCCTAATCGCCCCGCTCAT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MTDRPGNDVSARYATMTNRRTLLGAGLGLAAASLVSTTSASAQSETSNRSDATPITLQQGKSMGVRKLGSLEVSAIGLGC
LDMVGYYGGGPRDRKSMVSLIRAAFEQGVTFFDTAEVYGPYISEEYVAEALAPVRDQVVIATKFGFGVEEGQPTALNSQP
DHLRRAVDGSLKRLKTDHIDLLYQHRPDPNVPIEDVAEAVKDLIQAGKVKHWGLSEASAGTIRRAHAVHPVSAVQSEYAM
WWREPETRIFPTLEELGIGFVPYCPLGRSFLAGAVNPSQRFERTDRRHNLPRFTPEALAANMALFDYVRDWAQRKKTTPA
QFALAWILAQRPWIAPIPGTTQYPHLAENLGATGVQLTADELREIDAGLARIKLQGGRADPFTESQFDYS

Sequences:

>Translated_390_residues
MTDRPGNDVSARYATMTNRRTLLGAGLGLAAASLVSTTSASAQSETSNRSDATPITLQQGKSMGVRKLGSLEVSAIGLGC
LDMVGYYGGGPRDRKSMVSLIRAAFEQGVTFFDTAEVYGPYISEEYVAEALAPVRDQVVIATKFGFGVEEGQPTALNSQP
DHLRRAVDGSLKRLKTDHIDLLYQHRPDPNVPIEDVAEAVKDLIQAGKVKHWGLSEASAGTIRRAHAVHPVSAVQSEYAM
WWREPETRIFPTLEELGIGFVPYCPLGRSFLAGAVNPSQRFERTDRRHNLPRFTPEALAANMALFDYVRDWAQRKKTTPA
QFALAWILAQRPWIAPIPGTTQYPHLAENLGATGVQLTADELREIDAGLARIKLQGGRADPFTESQFDYS
>Mature_389_residues
TDRPGNDVSARYATMTNRRTLLGAGLGLAAASLVSTTSASAQSETSNRSDATPITLQQGKSMGVRKLGSLEVSAIGLGCL
DMVGYYGGGPRDRKSMVSLIRAAFEQGVTFFDTAEVYGPYISEEYVAEALAPVRDQVVIATKFGFGVEEGQPTALNSQPD
HLRRAVDGSLKRLKTDHIDLLYQHRPDPNVPIEDVAEAVKDLIQAGKVKHWGLSEASAGTIRRAHAVHPVSAVQSEYAMW
WREPETRIFPTLEELGIGFVPYCPLGRSFLAGAVNPSQRFERTDRRHNLPRFTPEALAANMALFDYVRDWAQRKKTTPAQ
FALAWILAQRPWIAPIPGTTQYPHLAENLGATGVQLTADELREIDAGLARIKLQGGRADPFTESQFDYS

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=343, Percent_Identity=28.5714285714286, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI27436969, Length=336, Percent_Identity=28.2738095238095, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI27436962, Length=380, Percent_Identity=27.8947368421053, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI27436966, Length=340, Percent_Identity=28.5294117647059, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI4504825, Length=323, Percent_Identity=28.1733746130031, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI27436971, Length=344, Percent_Identity=27.3255813953488, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI223718702, Length=226, Percent_Identity=30.5309734513274, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI41152114, Length=229, Percent_Identity=30.1310043668122, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI41327764, Length=141, Percent_Identity=31.9148936170213, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1787674, Length=311, Percent_Identity=30.8681672025724, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87081735, Length=314, Percent_Identity=30.8917197452229, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1789375, Length=316, Percent_Identity=28.4810126582279, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788070, Length=326, Percent_Identity=28.2208588957055, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788081, Length=301, Percent_Identity=25.5813953488372, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI48994888, Length=127, Percent_Identity=40.1574803149606, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1789199, Length=342, Percent_Identity=27.1929824561404, Blast_Score=83, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=27.0029673590504, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6323998, Length=323, Percent_Identity=26.9349845201238, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319958, Length=301, Percent_Identity=25.9136212624585, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322615, Length=251, Percent_Identity=27.0916334661355, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319951, Length=332, Percent_Identity=27.1084337349398, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325384, Length=297, Percent_Identity=26.9360269360269, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI45549126, Length=334, Percent_Identity=25.748502994012, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24640980, Length=334, Percent_Identity=25.748502994012, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 42714; Mature: 42582

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRPGNDVSARYATMTNRRTLLGAGLGLAAASLVSTTSASAQSETSNRSDATPITLQQG
CCCCCCCCCCHHHHHHCCCCHHHHCCHHHHHHHHHHHHCCCHHHCCCCCCCCCCEEECCC
KSMGVRKLGSLEVSAIGLGCLDMVGYYGGGPRDRKSMVSLIRAAFEQGVTFFDTAEVYGP
CCCCHHHHCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECHHHHCC
YISEEYVAEALAPVRDQVVIATKFGFGVEEGQPTALNSQPDHLRRAVDGSLKRLKTDHID
CCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LLYQHRPDPNVPIEDVAEAVKDLIQAGKVKHWGLSEASAGTIRRAHAVHPVSAVQSEYAM
HHEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHH
WWREPETRIFPTLEELGIGFVPYCPLGRSFLAGAVNPSQRFERTDRRHNLPRFTPEALAA
HHCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHH
NMALFDYVRDWAQRKKTTPAQFALAWILAQRPWIAPIPGTTQYPHLAENLGATGVQLTAD
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCEEECHH
ELREIDAGLARIKLQGGRADPFTESQFDYS
HHHHHHCCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDRPGNDVSARYATMTNRRTLLGAGLGLAAASLVSTTSASAQSETSNRSDATPITLQQG
CCCCCCCCCHHHHHHCCCCHHHHCCHHHHHHHHHHHHCCCHHHCCCCCCCCCCEEECCC
KSMGVRKLGSLEVSAIGLGCLDMVGYYGGGPRDRKSMVSLIRAAFEQGVTFFDTAEVYGP
CCCCHHHHCCEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEECHHHHCC
YISEEYVAEALAPVRDQVVIATKFGFGVEEGQPTALNSQPDHLRRAVDGSLKRLKTDHID
CCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LLYQHRPDPNVPIEDVAEAVKDLIQAGKVKHWGLSEASAGTIRRAHAVHPVSAVQSEYAM
HHEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHH
WWREPETRIFPTLEELGIGFVPYCPLGRSFLAGAVNPSQRFERTDRRHNLPRFTPEALAA
HHCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHH
NMALFDYVRDWAQRKKTTPAQFALAWILAQRPWIAPIPGTTQYPHLAENLGATGVQLTAD
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCEEECHH
ELREIDAGLARIKLQGGRADPFTESQFDYS
HHHHHHCCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]