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The map label for this gene is qseB [H]

Identifier: 150395854

GI number: 150395854

Start: 675487

End: 676158

Strand: Direct

Name: qseB [H]

Synonym: Smed_0630

Alternate gene names: 150395854

Gene position: 675487-676158 (Clockwise)

Preceding gene: 150395853

Following gene: 150395855

Centisome position: 17.86

GC content: 58.63

Gene sequence:

>672_bases
ATGCGCATTCTGATCGTCGAGGACGATACCAATCTGAACAGGCAATTGGCTGAAGCGCTGAAGGAGGCAGGCTACGTCGT
CGATCAGGCCTATGACGGTGAGGAAGGCCATTATCTCGGCGATGCGGAACCGTATGATGCGGTCATTCTCGATATCGGCC
TTCCCGAGATGGACGGCATCACCGTGCTCGAGAAATGGCGCGCAGACGGCAAAACCATGCCGGTGCTGATCCTGACTGCC
CGCGACCGATGGAGCGATAAAGTCGCGGGAATCGATGCCGGCGCCGACGATTATGTGGCAAAACCCTTCCATGTGGAGGA
GGTGCTCGCCCGCATCCGTGCATTGATCCGCCGTGCCGCCGGGCATGCAAGCTCCGAGATCGTATGTGGCCCGGTCCGCC
TCGATACCAAGGGCTCCAAGGCGACTGTCGCAGGTGTGGCGTTGAAGCTCACATCGCACGAGTTCCGCCTGCTATCCTAT
CTCATGCACCATATGGGGCAGGTGGTTTCCCGCACAGAGCTCGTCGAGCATATGTATGATCAGGATTTCGATCGCGATTC
CAACACGATCGAGGTCTTCATCGGCAGGCTCCGCAAGAAGATCGGCAACGACCTCATCGAAACGGTGCGCGGTCTCGGAT
ATCGCATGCAAGCACCCGGCGATGGCCATTAG

Upstream 100 bases:

>100_bases
GCTCATCCCCGGCAATGGAGGGCGCCCCAAGAAAGTCACGGTGAAGGTGCCTATGTAAGAGCTCTTTCGGGGTGTCCGAA
AGCAAGGGAAGTGGACGAGA

Downstream 100 bases:

>100_bases
ATCCCTTACTGCCCGTGTTCTGGCGGTTTCGACCGTTTGGGCAGTCGTTGCCCTGGTGGTGATCGGCATCGTCATTTCCG
CCCTTTACCGGCAGGGATCC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MRILIVEDDTNLNRQLAEALKEAGYVVDQAYDGEEGHYLGDAEPYDAVILDIGLPEMDGITVLEKWRADGKTMPVLILTA
RDRWSDKVAGIDAGADDYVAKPFHVEEVLARIRALIRRAAGHASSEIVCGPVRLDTKGSKATVAGVALKLTSHEFRLLSY
LMHHMGQVVSRTELVEHMYDQDFDRDSNTIEVFIGRLRKKIGNDLIETVRGLGYRMQAPGDGH

Sequences:

>Translated_223_residues
MRILIVEDDTNLNRQLAEALKEAGYVVDQAYDGEEGHYLGDAEPYDAVILDIGLPEMDGITVLEKWRADGKTMPVLILTA
RDRWSDKVAGIDAGADDYVAKPFHVEEVLARIRALIRRAAGHASSEIVCGPVRLDTKGSKATVAGVALKLTSHEFRLLSY
LMHHMGQVVSRTELVEHMYDQDFDRDSNTIEVFIGRLRKKIGNDLIETVRGLGYRMQAPGDGH
>Mature_223_residues
MRILIVEDDTNLNRQLAEALKEAGYVVDQAYDGEEGHYLGDAEPYDAVILDIGLPEMDGITVLEKWRADGKTMPVLILTA
RDRWSDKVAGIDAGADDYVAKPFHVEEVLARIRALIRRAAGHASSEIVCGPVRLDTKGSKATVAGVALKLTSHEFRLLSY
LMHHMGQVVSRTELVEHMYDQDFDRDSNTIEVFIGRLRKKIGNDLIETVRGLGYRMQAPGDGH

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=42.2018348623853, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI1789402, Length=216, Percent_Identity=45.8333333333333, Blast_Score=183, Evalue=9e-48,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=42.1052631578947, Blast_Score=178, Evalue=2e-46,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=44.4954128440367, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=39.6396396396396, Blast_Score=164, Evalue=3e-42,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=33.7777777777778, Blast_Score=124, Evalue=3e-30,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=33.7777777777778, Blast_Score=123, Evalue=8e-30,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=33.9285714285714, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=33.7837837837838, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=33.4821428571429, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=36.4035087719298, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=31.8777292576419, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=28.0701754385965, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=38.8888888888889, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=27.0742358078603, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788191, Length=118, Percent_Identity=37.2881355932203, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790299, Length=212, Percent_Identity=26.8867924528302, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790437, Length=123, Percent_Identity=31.7073170731707, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24802; Mature: 24802

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILIVEDDTNLNRQLAEALKEAGYVVDQAYDGEEGHYLGDAEPYDAVILDIGLPEMDGI
CEEEEEECCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCH
TVLEKWRADGKTMPVLILTARDRWSDKVAGIDAGADDYVAKPFHVEEVLARIRALIRRAA
HHHHHHCCCCCCCCEEEEECCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
GHASSEIVCGPVRLDTKGSKATVAGVALKLTSHEFRLLSYLMHHMGQVVSRTELVEHMYD
CCCCCCEEEECEEECCCCCCEEEEHEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDFDRDSNTIEVFIGRLRKKIGNDLIETVRGLGYRMQAPGDGH
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
>Mature Secondary Structure
MRILIVEDDTNLNRQLAEALKEAGYVVDQAYDGEEGHYLGDAEPYDAVILDIGLPEMDGI
CEEEEEECCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCH
TVLEKWRADGKTMPVLILTARDRWSDKVAGIDAGADDYVAKPFHVEEVLARIRALIRRAA
HHHHHHCCCCCCCCEEEEECCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
GHASSEIVCGPVRLDTKGSKATVAGVALKLTSHEFRLLSYLMHHMGQVVSRTELVEHMYD
CCCCCCEEEECEEECCCCCCEEEEHEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QDFDRDSNTIEVFIGRLRKKIGNDLIETVRGLGYRMQAPGDGH
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]