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The map label for this gene is spoVD

Identifier: 15004853

GI number: 15004853

Start: 160566

End: 162371

Strand: Direct

Name: spoVD

Synonym: CA_P0150

Alternate gene names: 15004853

Gene position: 160566-162371 (Clockwise)

Preceding gene: 15004851

Following gene: 15004854

Centisome position: 83.63

GC content: 35.05

Gene sequence:

>1806_bases
TTGAAACGCTCATCTGTAAATAAAAAAATACAATTATCAAAAAAACTCTTTCATGTTTTCTTTTTTTTAGTAGCAGTTTT
CTTTCTAATAATATTCAAACTCGCTTACATAATGATAGATAAGTCCGATGACTACAAGGCATATTCAATAAAACAATGGA
AGAACGAAATAACCATTGCCCCAAAAAGAGGAGACATCCTCGATTGTAATGGAGATAATCTAGCCACAAGCTTAAGTGAT
TATAGAATAGATGTAGACATGAACACACTTCTCTCTTCTTTAAAAAGCAACAAAATGACACTAAAAACTCTTTCTACTAA
GCTTGGAAAAATATTAGGGGAATCTTCTGACGACGTTTACTATACGCTGTCATCAAAATCTTCAAATGGAGTTCCCTTAA
GGTTTGTAAATCTTGTAAGGCAAATTAATAAGGAAAAAATAGATAGAGTAAAAGCTTTAAAAATAACTGGATTTATTTAT
TCTGATGATTTTCTTCGAGAATATCCAAACAATAATTTTCTTTCTAGTGTACTTGGCTACCTAAATTCCGATGGTAATGG
AGCTTCAGGCGTAGAGCTCTCCTATAATAAAATACTTTCAGGAACTCCTGGTCATAAAATCGTAGAAACAGATGTTATGA
GAAATCAGCTTCCCTACGGGAATTCCGAATATACAGCTCCTAAAGCCGGTAAGGATATAGTTCTAACCATAGATAAAAAT
ATTCAACTAATTGCTGAACAAGCTGCTGAAAAAGCATTGTCTGATAATAAAGCTAAATCTGTTACAATCACAGTTATGAA
CCCTAATAATGGTGAAATACTAGCCATGGTGTCCAAGCCTGATTTTAACCCTAATATCCCAAATAAGGGTAGCACAAATT
CTAATGTTAACGTATATAAAAATACTGCTGTTGAAAACACCTTCGAACCTGGCTCTATATTTAAAGTAATTACGTCCTAT
GCTGCCTTAGCTGAAAAGGTAGTTAACGATAATACTATCTTCACCTGCAATGGAAGCCTAGAAATCAATAAAAAAACTAT
TCATTGTTGGGAACCACAAGGTCACGGCAGAGAACATTTCGTTGATATCATCAAAAATTCCTGCAACGTTGGCTTTATGG
AATTAGGCGTTAATCTTCTTGGAAAAAATAAATTATACAAGTACGAAAAATTGTTTGGTTTTGGTGAAAAGACAGGAGTA
GATCTTCCAGATGAAGCAGCAGGTATAGTAAGACCACCTTCCGAAACTAGCCCTGTGGACTTAGCTAACAATTCTTTTGG
ACAAGGTGTTTCCGTAACCTCTGTTGAATATTTAGCAGCTTTTAACGCCATAGCAAATGGTGGAACCTGGATACGCCCTC
ATGTGATGAAGGAGATTGTCCATAGCGATGATAAAAATAGCAAAGTTATAGATGAACAATACTCCGATTATGATAAAAAA
ATGATATTAGACCCAGCTGTGGCAAGCAATTTAAGAAAATATCTAATCCATGTAGTTAACGATCCAACTGGTGTTGGAAA
AAAAGCTGCAATACCTGGATATGATATAGCAGGAAAAACCGGAACAGCTCAAAAGGCAGATCCTAAAACTGGTGGCTATG
AAACCGACAAATATATAGCTTCCTTTGCGGGCATGGCTCCAGCAAATAAACCTCGAATTACACTTTTAATTTCAGTTGAT
GAGCCTGATGCGGCTACAAATTACTACGCTTCTACTGTTGCTGCACCTGTGGCAAAAGATCTTTACATTAAAATATTTGA
CTATTTAGCTCTAGAGGGCATATATAATATATCCTCTAAAAAGTAA

Upstream 100 bases:

>100_bases
GCTATTAATTTCTCTCCTTGCTTACAATAATTGTAAAAACATATAAATATATGCTATTATATATTTGGTATATTTTTACA
ATTGGAAATGAGGTGTAAGA

Downstream 100 bases:

>100_bases
AAGAGCCGAAACCTTCTTCTCCTTTGCAACTATATATTTATATATAGTACTCTGTAAATTAATTGCTCAACAAAAAAATA
TTATATTTTTAGTCTTAATT

Product: stage V sporulation protein D, penicillin-binding protein

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 601; Mature: 601

Protein sequence:

>601_residues
MKRSSVNKKIQLSKKLFHVFFFLVAVFFLIIFKLAYIMIDKSDDYKAYSIKQWKNEITIAPKRGDILDCNGDNLATSLSD
YRIDVDMNTLLSSLKSNKMTLKTLSTKLGKILGESSDDVYYTLSSKSSNGVPLRFVNLVRQINKEKIDRVKALKITGFIY
SDDFLREYPNNNFLSSVLGYLNSDGNGASGVELSYNKILSGTPGHKIVETDVMRNQLPYGNSEYTAPKAGKDIVLTIDKN
IQLIAEQAAEKALSDNKAKSVTITVMNPNNGEILAMVSKPDFNPNIPNKGSTNSNVNVYKNTAVENTFEPGSIFKVITSY
AALAEKVVNDNTIFTCNGSLEINKKTIHCWEPQGHGREHFVDIIKNSCNVGFMELGVNLLGKNKLYKYEKLFGFGEKTGV
DLPDEAAGIVRPPSETSPVDLANNSFGQGVSVTSVEYLAAFNAIANGGTWIRPHVMKEIVHSDDKNSKVIDEQYSDYDKK
MILDPAVASNLRKYLIHVVNDPTGVGKKAAIPGYDIAGKTGTAQKADPKTGGYETDKYIASFAGMAPANKPRITLLISVD
EPDAATNYYASTVAAPVAKDLYIKIFDYLALEGIYNISSKK

Sequences:

>Translated_601_residues
MKRSSVNKKIQLSKKLFHVFFFLVAVFFLIIFKLAYIMIDKSDDYKAYSIKQWKNEITIAPKRGDILDCNGDNLATSLSD
YRIDVDMNTLLSSLKSNKMTLKTLSTKLGKILGESSDDVYYTLSSKSSNGVPLRFVNLVRQINKEKIDRVKALKITGFIY
SDDFLREYPNNNFLSSVLGYLNSDGNGASGVELSYNKILSGTPGHKIVETDVMRNQLPYGNSEYTAPKAGKDIVLTIDKN
IQLIAEQAAEKALSDNKAKSVTITVMNPNNGEILAMVSKPDFNPNIPNKGSTNSNVNVYKNTAVENTFEPGSIFKVITSY
AALAEKVVNDNTIFTCNGSLEINKKTIHCWEPQGHGREHFVDIIKNSCNVGFMELGVNLLGKNKLYKYEKLFGFGEKTGV
DLPDEAAGIVRPPSETSPVDLANNSFGQGVSVTSVEYLAAFNAIANGGTWIRPHVMKEIVHSDDKNSKVIDEQYSDYDKK
MILDPAVASNLRKYLIHVVNDPTGVGKKAAIPGYDIAGKTGTAQKADPKTGGYETDKYIASFAGMAPANKPRITLLISVD
EPDAATNYYASTVAAPVAKDLYIKIFDYLALEGIYNISSKK
>Mature_601_residues
MKRSSVNKKIQLSKKLFHVFFFLVAVFFLIIFKLAYIMIDKSDDYKAYSIKQWKNEITIAPKRGDILDCNGDNLATSLSD
YRIDVDMNTLLSSLKSNKMTLKTLSTKLGKILGESSDDVYYTLSSKSSNGVPLRFVNLVRQINKEKIDRVKALKITGFIY
SDDFLREYPNNNFLSSVLGYLNSDGNGASGVELSYNKILSGTPGHKIVETDVMRNQLPYGNSEYTAPKAGKDIVLTIDKN
IQLIAEQAAEKALSDNKAKSVTITVMNPNNGEILAMVSKPDFNPNIPNKGSTNSNVNVYKNTAVENTFEPGSIFKVITSY
AALAEKVVNDNTIFTCNGSLEINKKTIHCWEPQGHGREHFVDIIKNSCNVGFMELGVNLLGKNKLYKYEKLFGFGEKTGV
DLPDEAAGIVRPPSETSPVDLANNSFGQGVSVTSVEYLAAFNAIANGGTWIRPHVMKEIVHSDDKNSKVIDEQYSDYDKK
MILDPAVASNLRKYLIHVVNDPTGVGKKAAIPGYDIAGKTGTAQKADPKTGGYETDKYIASFAGMAPANKPRITLLISVD
EPDAATNYYASTVAAPVAKDLYIKIFDYLALEGIYNISSKK

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=565, Percent_Identity=27.787610619469, Blast_Score=194, Evalue=2e-50,
Organism=Escherichia coli, GI1786854, Length=652, Percent_Identity=23.6196319018405, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 66176; Mature: 66176

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSSVNKKIQLSKKLFHVFFFLVAVFFLIIFKLAYIMIDKSDDYKAYSIKQWKNEITIA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEHHHCCCCEEEE
PKRGDILDCNGDNLATSLSDYRIDVDMNTLLSSLKSNKMTLKTLSTKLGKILGESSDDVY
CCCCCEEECCCCCCEECCCCEEEEEEHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCCEE
YTLSSKSSNGVPLRFVNLVRQINKEKIDRVKALKITGFIYSDDFLREYPNNNFLSSVLGY
EEEECCCCCCCCHHHHHHHHHHCHHHHHHEEEEEEEEEEECCHHHHHCCCCHHHHHHHHH
LNSDGNGASGVELSYNKILSGTPGHKIVETDVMRNQLPYGNSEYTAPKAGKDIVLTIDKN
HCCCCCCCCCEEEEHHHHCCCCCCCEEEEHHHHHHCCCCCCCCCCCCCCCCEEEEEECCC
IQLIAEQAAEKALSDNKAKSVTITVMNPNNGEILAMVSKPDFNPNIPNKGSTNSNVNVYK
HHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEE
NTAVENTFEPGSIFKVITSYAALAEKVVNDNTIFTCNGSLEINKKTIHCWEPQGHGREHF
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEECCCEEEEECCCCCCHHHH
VDIIKNSCNVGFMELGVNLLGKNKLYKYEKLFGFGEKTGVDLPDEAAGIVRPPSETSPVD
HHHHHCCCCCCHHHHCCHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LANNSFGQGVSVTSVEYLAAFNAIANGGTWIRPHVMKEIVHSDDKNSKVIDEQYSDYDKK
CCCCCCCCCCEEHHHHHHHHHHHHCCCCCEECHHHHHHHHHCCCCCCCCHHHHHHCCCCE
MILDPAVASNLRKYLIHVVNDPTGVGKKAAIPGYDIAGKTGTAQKADPKTGGYETDKYIA
EEECHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
SFAGMAPANKPRITLLISVDEPDAATNYYASTVAAPVAKDLYIKIFDYLALEGIYNISSK
HHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
K
C
>Mature Secondary Structure
MKRSSVNKKIQLSKKLFHVFFFLVAVFFLIIFKLAYIMIDKSDDYKAYSIKQWKNEITIA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEHHHCCCCEEEE
PKRGDILDCNGDNLATSLSDYRIDVDMNTLLSSLKSNKMTLKTLSTKLGKILGESSDDVY
CCCCCEEECCCCCCEECCCCEEEEEEHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCCEE
YTLSSKSSNGVPLRFVNLVRQINKEKIDRVKALKITGFIYSDDFLREYPNNNFLSSVLGY
EEEECCCCCCCCHHHHHHHHHHCHHHHHHEEEEEEEEEEECCHHHHHCCCCHHHHHHHHH
LNSDGNGASGVELSYNKILSGTPGHKIVETDVMRNQLPYGNSEYTAPKAGKDIVLTIDKN
HCCCCCCCCCEEEEHHHHCCCCCCCEEEEHHHHHHCCCCCCCCCCCCCCCCEEEEEECCC
IQLIAEQAAEKALSDNKAKSVTITVMNPNNGEILAMVSKPDFNPNIPNKGSTNSNVNVYK
HHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEE
NTAVENTFEPGSIFKVITSYAALAEKVVNDNTIFTCNGSLEINKKTIHCWEPQGHGREHF
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEECCCEEEEECCCCCCHHHH
VDIIKNSCNVGFMELGVNLLGKNKLYKYEKLFGFGEKTGVDLPDEAAGIVRPPSETSPVD
HHHHHCCCCCCHHHHCCHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
LANNSFGQGVSVTSVEYLAAFNAIANGGTWIRPHVMKEIVHSDDKNSKVIDEQYSDYDKK
CCCCCCCCCCEEHHHHHHHHHHHHCCCCCEECHHHHHHHHHCCCCCCCCHHHHHHCCCCE
MILDPAVASNLRKYLIHVVNDPTGVGKKAAIPGYDIAGKTGTAQKADPKTGGYETDKYIA
EEECHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHH
SFAGMAPANKPRITLLISVDEPDAATNYYASTVAAPVAKDLYIKIFDYLALEGIYNISSK
HHHCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]