Click here to switch to the map view.

The map label for this gene is Not Available

Identifier: 15004812

GI number: 15004812

Start: 114920

End: 116557

Strand: Direct

Name: Not Available

Synonym: CA_P0109

Alternate gene names: 15004812

Gene position: 114920-116557 (Clockwise)

Preceding gene: 15004811

Following gene: 15004813

Centisome position: 59.85

GC content: 31.81

Gene sequence:

>1638_bases
ATGAATAAAAAATATCAGATCATTTCTTTTATAGCCATTGTTTTAGGTTTTTTTATGACATTACTAGATACAACTATAGT
AAATATTACTTTACCTAAGATGACTGAATACTTTAATACTAATATGAATCATATTTCCTGGGTAGTAAACGCCTATAATC
TAGCTTTTGCAGTTATTATACTGACGGCTTCAAGATTAGCAGATCAATTTGGCAGAAAAAAAATATTCATAGGGGGCGTT
TTTTTATTCACCATAGCTTCATTATTGGCGGGTATTTCAAATTCTCTTGAAGTACTTATATTTCTTCGAGCACTTCAAGG
ACTATCTGCAGCCTTTGTTGTTCCTGTTACAATGCCTCTTTCTGCTGAAATATTCCCACCAGAAAAGAGAGGAACTATTA
TGTCACTTTGGGGAGCTTTCGCCGGTCTTGCTGCTGCTAGTGGACCAACACTTGGTGGTATATTAACACAATTTTTTAAT
TGGAGATATATCTTCTTTATTAATGTACCTATAGGATGCCTTTGCATATTTTTAACTATTAAATTCATAAAAGAATCTTA
TGATCAGGCTGCAAGCAAAAGTATAGACTTTGGAGGAAACATAACAATCTCAGCTGCTATGTTTTTCTTAACCTTTGCAC
TAATAAAGGTTAATGAAAAAGGCTGGACTTCAAGCTTTACACTCTCTTTATTTGCTGCTTCAGCTATAACTCTTATAATA
TTTATAATTATCGAGCTAAAAGTTAATGAGCCTATGCTTTCTCTTAGTCTATTTAAATCTTTACAATTTACAAACGGATC
TATTTCTCTATTTTTACTTGGGCTTGGTATGATGTGTGGCTCCTATTTTTTGTCCTTTTTTCTAACGCAGATTAAAGGAT
TAAATGAACTGTCAGCAGGCCTTATCATTTCAACTATGTCCCTAAGTTCAATGTTTTTTTCAATAGTAGCTGCTATCTTA
ACAAAAAAGGTTGGAAAGCGATTTATTAGCGCATTTGGCATTTTTCTTTTATGCTTCTCTTGCTACTTAAATAGCTCTCT
TACTCAAAACTCTTCAAATATAGATGTCATTTTAAGATTAATTATTACTGGTGCTGGTACAGGCTTAAGTATGGCTACAC
TATTAAGTTCTACAATTGCTAATGTCCCTATAAATAAAATAGGAATAGCTTCTGGAATAGATAACATGACACGAACACTT
GGAACTGTGCTTGGAGTTGCACTATTTTTGACTATATTTACATCAAATATGGCTATTCAGATAACTGATGCAAAAAAAGC
TGTTATCCAAACAATACATAGTGACACTGTTTTTGATGATAAAACCAAGCTTAAGATGATTTCTTCGATAAAAGTATCTA
GTGAACAAACCGTTAGTCTTTTAAAAATATTAAACACAATTGACAAAAAAGAAACCTCTGTATTAGCATCTTCTCCTTCC
ATGTATAAAGATAAAATCAAGGCAGGTTTTGAAACTCAAAAGAAAGAAATAAAAAAAGTAGTTCCTACTATACAGCATGT
TTTTTTATCGTATACTGTTAAAGCTTTTAGTTTTACATTTGAAGCTGGAGCTATAATTCTTTTCCCAGGTGTACTTTTTG
CATTGTTCAGTGATAAAAGAAGAGAAAAAAGTAATTAA

Upstream 100 bases:

>100_bases
GGTATATCTTTATTGAGAGACATTTTTTTCGCCCAACTACTATACATTATAGTAGTCTATTATATACTAATATATTTTAT
ATCTTTAGGAGGTTTATTTT

Downstream 100 bases:

>100_bases
TATTATGAAATCCGTGCATGATTATTTGATGCACGGAAAATCACAATATGTAAGCTTGTGCATGTTCTACACTATCGAAG
CCGTGAGTTACTTGTAAATA

Product: permease MDR type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MNKKYQIISFIAIVLGFFMTLLDTTIVNITLPKMTEYFNTNMNHISWVVNAYNLAFAVIILTASRLADQFGRKKIFIGGV
FLFTIASLLAGISNSLEVLIFLRALQGLSAAFVVPVTMPLSAEIFPPEKRGTIMSLWGAFAGLAAASGPTLGGILTQFFN
WRYIFFINVPIGCLCIFLTIKFIKESYDQAASKSIDFGGNITISAAMFFLTFALIKVNEKGWTSSFTLSLFAASAITLII
FIIIELKVNEPMLSLSLFKSLQFTNGSISLFLLGLGMMCGSYFLSFFLTQIKGLNELSAGLIISTMSLSSMFFSIVAAIL
TKKVGKRFISAFGIFLLCFSCYLNSSLTQNSSNIDVILRLIITGAGTGLSMATLLSSTIANVPINKIGIASGIDNMTRTL
GTVLGVALFLTIFTSNMAIQITDAKKAVIQTIHSDTVFDDKTKLKMISSIKVSSEQTVSLLKILNTIDKKETSVLASSPS
MYKDKIKAGFETQKKEIKKVVPTIQHVFLSYTVKAFSFTFEAGAIILFPGVLFALFSDKRREKSN

Sequences:

>Translated_545_residues
MNKKYQIISFIAIVLGFFMTLLDTTIVNITLPKMTEYFNTNMNHISWVVNAYNLAFAVIILTASRLADQFGRKKIFIGGV
FLFTIASLLAGISNSLEVLIFLRALQGLSAAFVVPVTMPLSAEIFPPEKRGTIMSLWGAFAGLAAASGPTLGGILTQFFN
WRYIFFINVPIGCLCIFLTIKFIKESYDQAASKSIDFGGNITISAAMFFLTFALIKVNEKGWTSSFTLSLFAASAITLII
FIIIELKVNEPMLSLSLFKSLQFTNGSISLFLLGLGMMCGSYFLSFFLTQIKGLNELSAGLIISTMSLSSMFFSIVAAIL
TKKVGKRFISAFGIFLLCFSCYLNSSLTQNSSNIDVILRLIITGAGTGLSMATLLSSTIANVPINKIGIASGIDNMTRTL
GTVLGVALFLTIFTSNMAIQITDAKKAVIQTIHSDTVFDDKTKLKMISSIKVSSEQTVSLLKILNTIDKKETSVLASSPS
MYKDKIKAGFETQKKEIKKVVPTIQHVFLSYTVKAFSFTFEAGAIILFPGVLFALFSDKRREKSN
>Mature_545_residues
MNKKYQIISFIAIVLGFFMTLLDTTIVNITLPKMTEYFNTNMNHISWVVNAYNLAFAVIILTASRLADQFGRKKIFIGGV
FLFTIASLLAGISNSLEVLIFLRALQGLSAAFVVPVTMPLSAEIFPPEKRGTIMSLWGAFAGLAAASGPTLGGILTQFFN
WRYIFFINVPIGCLCIFLTIKFIKESYDQAASKSIDFGGNITISAAMFFLTFALIKVNEKGWTSSFTLSLFAASAITLII
FIIIELKVNEPMLSLSLFKSLQFTNGSISLFLLGLGMMCGSYFLSFFLTQIKGLNELSAGLIISTMSLSSMFFSIVAAIL
TKKVGKRFISAFGIFLLCFSCYLNSSLTQNSSNIDVILRLIITGAGTGLSMATLLSSTIANVPINKIGIASGIDNMTRTL
GTVLGVALFLTIFTSNMAIQITDAKKAVIQTIHSDTVFDDKTKLKMISSIKVSSEQTVSLLKILNTIDKKETSVLASSPS
MYKDKIKAGFETQKKEIKKVVPTIQHVFLSYTVKAFSFTFEAGAIILFPGVLFALFSDKRREKSN

Specific function: Resistance to tetracenomycin C by an active tetracenomycin C efflux system which is probably energized by transmembrane electrochemical gradients [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=427, Percent_Identity=28.5714285714286, Blast_Score=168, Evalue=6e-43,
Organism=Escherichia coli, GI1789042, Length=424, Percent_Identity=27.122641509434, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI1788710, Length=466, Percent_Identity=28.755364806867, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI1790195, Length=314, Percent_Identity=27.7070063694268, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI1788392, Length=317, Percent_Identity=30.2839116719243, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1788509, Length=200, Percent_Identity=27.5, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790146, Length=192, Percent_Identity=24.4791666666667, Blast_Score=63, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6324954, Length=233, Percent_Identity=30.4721030042918, Blast_Score=97, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6322958, Length=167, Percent_Identity=29.3413173652695, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6321663, Length=152, Percent_Identity=26.9736842105263, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6325455, Length=146, Percent_Identity=30.1369863013699, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6319770, Length=456, Percent_Identity=24.1228070175439, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6324264, Length=161, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6323520, Length=256, Percent_Identity=26.171875, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6323735, Length=245, Percent_Identity=26.1224489795918, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 59600; Mature: 59600

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKYQIISFIAIVLGFFMTLLDTTIVNITLPKMTEYFNTNMNHISWVVNAYNLAFAVII
CCCCHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LTASRLADQFGRKKIFIGGVFLFTIASLLAGISNSLEVLIFLRALQGLSAAFVVPVTMPL
HHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEEECCC
SAEIFPPEKRGTIMSLWGAFAGLAAASGPTLGGILTQFFNWRYIFFINVPIGCLCIFLTI
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEEEEECCHHHHHHHHHH
KFIKESYDQAASKSIDFGGNITISAAMFFLTFALIKVNEKGWTSSFTLSLFAASAITLII
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
FIIIELKVNEPMLSLSLFKSLQFTNGSISLFLLGLGMMCGSYFLSFFLTQIKGLNELSAG
HHHHHEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LIISTMSLSSMFFSIVAAILTKKVGKRFISAFGIFLLCFSCYLNSSLTQNSSNIDVILRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
IITGAGTGLSMATLLSSTIANVPINKIGIASGIDNMTRTLGTVLGVALFLTIFTSNMAIQ
HHHCCCCCHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEE
ITDAKKAVIQTIHSDTVFDDKTKLKMISSIKVSSEQTVSLLKILNTIDKKETSVLASSPS
EECHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHCCCCH
MYKDKIKAGFETQKKEIKKVVPTIQHVFLSYTVKAFSFTFEAGAIILFPGVLFALFSDKR
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHH
REKSN
HCCCC
>Mature Secondary Structure
MNKKYQIISFIAIVLGFFMTLLDTTIVNITLPKMTEYFNTNMNHISWVVNAYNLAFAVII
CCCCHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LTASRLADQFGRKKIFIGGVFLFTIASLLAGISNSLEVLIFLRALQGLSAAFVVPVTMPL
HHHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEEEECCC
SAEIFPPEKRGTIMSLWGAFAGLAAASGPTLGGILTQFFNWRYIFFINVPIGCLCIFLTI
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEEEEECCHHHHHHHHHH
KFIKESYDQAASKSIDFGGNITISAAMFFLTFALIKVNEKGWTSSFTLSLFAASAITLII
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
FIIIELKVNEPMLSLSLFKSLQFTNGSISLFLLGLGMMCGSYFLSFFLTQIKGLNELSAG
HHHHHEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LIISTMSLSSMFFSIVAAILTKKVGKRFISAFGIFLLCFSCYLNSSLTQNSSNIDVILRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
IITGAGTGLSMATLLSSTIANVPINKIGIASGIDNMTRTLGTVLGVALFLTIFTSNMAIQ
HHHCCCCCHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEE
ITDAKKAVIQTIHSDTVFDDKTKLKMISSIKVSSEQTVSLLKILNTIDKKETSVLASSPS
EECHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHCCCCH
MYKDKIKAGFETQKKEIKKVVPTIQHVFLSYTVKAFSFTFEAGAIILFPGVLFALFSDKR
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHH
REKSN
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1592819 [H]