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The map label for this gene is glyQS [H]

Identifier: 150009785

GI number: 150009785

Start: 3874364

End: 3875908

Strand: Direct

Name: glyQS [H]

Synonym: BDI_3201

Alternate gene names: 150009785

Gene position: 3874364-3875908 (Clockwise)

Preceding gene: 150009783

Following gene: 150009786

Centisome position: 80.53

GC content: 46.21

Gene sequence:

>1545_bases
ATGGCACAAGAAGATGTATTTAAGAAATTAGTTTCACACTGTAAGGAGTATGGTTTCGTATTTCCCTCCTCAGAGATTTA
TGACGGTTTGGGAGCGGTATACGATTATGGCCAGTATGGTGTTGAGTTAAAGAATAATATAAAGAAATATTGGTGGGATA
GCATGACTTTGCTGCATGAGAATGTAGTGGGTATTGATTCCGCTATTTTTATGCACCCTACTATCTGGAAAGCTTCCGGC
CATGTTGACGCTTTTAATGATCCGTTGATCGATAACAAGGACTCGAAGAAACGTTACCGTGCGGACGTTTTGATCGAGGA
CCATTTGGGCAAGATCGAGGAGAAAATAAATAAGGAAGTGGCGAAAGCCGCAAAGAAATTCGGTGACGCTTTCGATGAGG
CTAAATTCCGTGAGACGAATCCTCGTGTATTGGAGCATCAAGCGAAATGGAATGAGATTCATGAGCGTTATAGCAAGGCG
ATGAACGAGTCTAACTTCGAGGATCTTCGCCAATTGATCTTGGATTGCGAGATCGTTTGCCCGATTTCCGGAACTCGTAA
CTGGACGGAGGTTCGCCAGTTTAACTTGATGTTCTCTACGGATATGGGTTCTACCGCTGATGGAGCGATGAAGGTTTATC
TTCGTCCGGAGACGGCCCAAGGTATTTTCGTGAACTTCTTGAATGTGCAGAAGACAGGCCGTATGAAGATCCCGTTCGGT
ATCGCCCAGATCGGTAAGGCGTTCCGTAATGAGATCGTGGCTCGCCAGTTTATCTTCCGTATGCGTGAGTTCGAGCAAAT
GGAGATGCAATTCTTCGTTCGTCCGGGTGAGGAGATCGAGTGGTTTAAGAAATGGAAGTCTACTCGTTTGAAATGGCATC
AAGCCCTAGGTTTGGGCGATGAGAAGTATCGCTATCACGATCATGAGAAATTGGCTCACTACGCTAACGCGGCTACGGAT
ATCGAGTTCGAGATGCCATTCGGATTTAAGGAAGTGGAGGGTATACATAGCCGTACGAACTTCGACTTGAGTCAGCATGA
GAAGTTTTCCGGTAAAAAGATCCAATATTTCGATCCGGAGTTGAACCAGAGTTACACTCCGTATGTAATCGAGACCTCGA
TCGGTGTAGACCGTGTGTTCTTGAGCATCATGGCGGGTTCTTACTGCGAGGAGACGTTGGCGAATGGCGAGAGCCGTGTG
GTATTGAAGTTGCCCGCAGCCTTGGCTCCGATCAAATTGGCCGTATTGCCATTGGTGAAGAAAGATGGCCTGCCCGAGAA
AGCTGAGGAGATTATAAATATGTTGCGTTTCGACTTCCGTTGCCAATACGACGAGAAGGATTCTATTGGTAAGCGTTATC
GCCGTCAGGATGCGATCGGTACCCCGTATTGTATTACGGTAGACCATGACACCTTGAAGGATAACTGCGTAACGATCCGT
TTCCGTGACACGATGGAGCAAGAGCGCGTAAGCATCGATAAGCTTCACGATATTATCACGGAGAAGGTGAGCATGAAGAA
TTTATTGAAAAAGGTAATAGAGTAA

Upstream 100 bases:

>100_bases
CATAAAGGAGACCATGTGCTAATGTGTCACTCAGGCGGGTCTCCGATGGACTTATCATTGGCACATTGGCATATTAACAA
AATTGGCAAATTATTAGATT

Downstream 100 bases:

>100_bases
ACGAATGAAGAAGTACTGGCATATTGCGTTGATGTTGTTTTGCGTGCTCATGATCACCTCTTGTGGGGATGATGATGAGG
CACTAGAGGTGGATGAGGTT

Product: glycyl-tRNA synthetase

Products: NA

Alternate protein names: Glycine--tRNA ligase; GlyRS [H]

Number of amino acids: Translated: 514; Mature: 513

Protein sequence:

>514_residues
MAQEDVFKKLVSHCKEYGFVFPSSEIYDGLGAVYDYGQYGVELKNNIKKYWWDSMTLLHENVVGIDSAIFMHPTIWKASG
HVDAFNDPLIDNKDSKKRYRADVLIEDHLGKIEEKINKEVAKAAKKFGDAFDEAKFRETNPRVLEHQAKWNEIHERYSKA
MNESNFEDLRQLILDCEIVCPISGTRNWTEVRQFNLMFSTDMGSTADGAMKVYLRPETAQGIFVNFLNVQKTGRMKIPFG
IAQIGKAFRNEIVARQFIFRMREFEQMEMQFFVRPGEEIEWFKKWKSTRLKWHQALGLGDEKYRYHDHEKLAHYANAATD
IEFEMPFGFKEVEGIHSRTNFDLSQHEKFSGKKIQYFDPELNQSYTPYVIETSIGVDRVFLSIMAGSYCEETLANGESRV
VLKLPAALAPIKLAVLPLVKKDGLPEKAEEIINMLRFDFRCQYDEKDSIGKRYRRQDAIGTPYCITVDHDTLKDNCVTIR
FRDTMEQERVSIDKLHDIITEKVSMKNLLKKVIE

Sequences:

>Translated_514_residues
MAQEDVFKKLVSHCKEYGFVFPSSEIYDGLGAVYDYGQYGVELKNNIKKYWWDSMTLLHENVVGIDSAIFMHPTIWKASG
HVDAFNDPLIDNKDSKKRYRADVLIEDHLGKIEEKINKEVAKAAKKFGDAFDEAKFRETNPRVLEHQAKWNEIHERYSKA
MNESNFEDLRQLILDCEIVCPISGTRNWTEVRQFNLMFSTDMGSTADGAMKVYLRPETAQGIFVNFLNVQKTGRMKIPFG
IAQIGKAFRNEIVARQFIFRMREFEQMEMQFFVRPGEEIEWFKKWKSTRLKWHQALGLGDEKYRYHDHEKLAHYANAATD
IEFEMPFGFKEVEGIHSRTNFDLSQHEKFSGKKIQYFDPELNQSYTPYVIETSIGVDRVFLSIMAGSYCEETLANGESRV
VLKLPAALAPIKLAVLPLVKKDGLPEKAEEIINMLRFDFRCQYDEKDSIGKRYRRQDAIGTPYCITVDHDTLKDNCVTIR
FRDTMEQERVSIDKLHDIITEKVSMKNLLKKVIE
>Mature_513_residues
AQEDVFKKLVSHCKEYGFVFPSSEIYDGLGAVYDYGQYGVELKNNIKKYWWDSMTLLHENVVGIDSAIFMHPTIWKASGH
VDAFNDPLIDNKDSKKRYRADVLIEDHLGKIEEKINKEVAKAAKKFGDAFDEAKFRETNPRVLEHQAKWNEIHERYSKAM
NESNFEDLRQLILDCEIVCPISGTRNWTEVRQFNLMFSTDMGSTADGAMKVYLRPETAQGIFVNFLNVQKTGRMKIPFGI
AQIGKAFRNEIVARQFIFRMREFEQMEMQFFVRPGEEIEWFKKWKSTRLKWHQALGLGDEKYRYHDHEKLAHYANAATDI
EFEMPFGFKEVEGIHSRTNFDLSQHEKFSGKKIQYFDPELNQSYTPYVIETSIGVDRVFLSIMAGSYCEETLANGESRVV
LKLPAALAPIKLAVLPLVKKDGLPEKAEEIINMLRFDFRCQYDEKDSIGKRYRRQDAIGTPYCITVDHDTLKDNCVTIRF
RDTMEQERVSIDKLHDIITEKVSMKNLLKKVIE

Specific function: Catalyzes the attachment of glycine to tRNA(Gly) [H]

COG id: COG0423

COG function: function code J; Glycyl-tRNA synthetase (class II)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI116805340, Length=367, Percent_Identity=28.6103542234332, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI70887790, Length=310, Percent_Identity=22.258064516129, Blast_Score=69, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17554996, Length=376, Percent_Identity=30.0531914893617, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI32564541, Length=376, Percent_Identity=30.0531914893617, Blast_Score=146, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6325338, Length=399, Percent_Identity=30.8270676691729, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6319597, Length=386, Percent_Identity=28.2383419689119, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21357965, Length=376, Percent_Identity=29.2553191489362, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24664462, Length=376, Percent_Identity=29.2553191489362, Blast_Score=150, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR022961
- InterPro:   IPR002315 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b [H]

EC number: =6.1.1.14 [H]

Molecular weight: Translated: 59847; Mature: 59716

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQEDVFKKLVSHCKEYGFVFPSSEIYDGLGAVYDYGQYGVELKNNIKKYWWDSMTLLHE
CCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
NVVGIDSAIFMHPTIWKASGHVDAFNDPLIDNKDSKKRYRADVLIEDHLGKIEEKINKEV
HHHCCCCCEEECCEEEECCCCCCCCCCCCCCCCCHHHHHHHHEEEHHHHHHHHHHHHHHH
AKAAKKFGDAFDEAKFRETNPRVLEHQAKWNEIHERYSKAMNESNFEDLRQLILDCEIVC
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEE
PISGTRNWTEVRQFNLMFSTDMGSTADGAMKVYLRPETAQGIFVNFLNVQKTGRMKIPFG
CCCCCCCHHHHHHEEEEEECCCCCCCCCEEEEEECCCCCCCEEEEEEEECCCCCEECCCC
IAQIGKAFRNEIVARQFIFRMREFEQMEMQFFVRPGEEIEWFKKWKSTRLKWHQALGLGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHCCCC
EKYRYHDHEKLAHYANAATDIEFEMPFGFKEVEGIHSRTNFDLSQHEKFSGKKIQYFDPE
HHHHHCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCC
LNQSYTPYVIETSIGVDRVFLSIMAGSYCEETLANGESRVVLKLPAALAPIKLAVLPLVK
CCCCCCCEEEEECCCHHHHHHHHHHCHHHHHHHCCCCCEEEEEECCHHCCHHHHHHHHHH
KDGLPEKAEEIINMLRFDFRCQYDEKDSIGKRYRRQDAIGTPYCITVDHDTLKDNCVTIR
CCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEE
FRDTMEQERVSIDKLHDIITEKVSMKNLLKKVIE
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AQEDVFKKLVSHCKEYGFVFPSSEIYDGLGAVYDYGQYGVELKNNIKKYWWDSMTLLHE
CHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
NVVGIDSAIFMHPTIWKASGHVDAFNDPLIDNKDSKKRYRADVLIEDHLGKIEEKINKEV
HHHCCCCCEEECCEEEECCCCCCCCCCCCCCCCCHHHHHHHHEEEHHHHHHHHHHHHHHH
AKAAKKFGDAFDEAKFRETNPRVLEHQAKWNEIHERYSKAMNESNFEDLRQLILDCEIVC
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCEEEE
PISGTRNWTEVRQFNLMFSTDMGSTADGAMKVYLRPETAQGIFVNFLNVQKTGRMKIPFG
CCCCCCCHHHHHHEEEEEECCCCCCCCCEEEEEECCCCCCCEEEEEEEECCCCCEECCCC
IAQIGKAFRNEIVARQFIFRMREFEQMEMQFFVRPGEEIEWFKKWKSTRLKWHQALGLGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHCCCC
EKYRYHDHEKLAHYANAATDIEFEMPFGFKEVEGIHSRTNFDLSQHEKFSGKKIQYFDPE
HHHHHCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCC
LNQSYTPYVIETSIGVDRVFLSIMAGSYCEETLANGESRVVLKLPAALAPIKLAVLPLVK
CCCCCCCEEEEECCCHHHHHHHHHHCHHHHHHHCCCCCEEEEEECCHHCCHHHHHHHHHH
KDGLPEKAEEIINMLRFDFRCQYDEKDSIGKRYRRQDAIGTPYCITVDHDTLKDNCVTIR
CCCCCHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEE
FRDTMEQERVSIDKLHDIITEKVSMKNLLKKVIE
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]