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The map label for this gene is ppnK [H]

Identifier: 150008177

GI number: 150008177

Start: 1808236

End: 1809111

Strand: Reverse

Name: ppnK [H]

Synonym: BDI_1543

Alternate gene names: 150008177

Gene position: 1809111-1808236 (Counterclockwise)

Preceding gene: 150008178

Following gene: 150008176

Centisome position: 37.6

GC content: 44.98

Gene sequence:

>876_bases
ATGAAAGTTGGAATATTTGGAAGTGAATATCAGATCGAGAGACAGAATCTGATTAAACGCCTGTTTGAGAAGCTTCGTGA
ACAAGAGGCTGATATTTATGTGGACAGCCCTTTTTATACATTCCTTACCGATGCTTTTGGTTTTGAGCCAGTGGTGAGCG
GGCTATTAGTGGGTGATGAGTTTGATCTGGATATAGCCCTTAGCGTGGGAGGAGATGGTACGTTCCTTCGTACGGCGGCC
CGGGTAAATAAACAGGATATCCCTATTTTAGGCATTAATACCGGACGGCTGGGTTTCCTTGCGGATGTCAGCAGTAATGA
GGTTGAGGATACGCTGGATGAGATTTTTAAGAATTACTATAAGGTAGAGGAACGAACCCTCTTGCGTTTATATACGGAAG
ACCGTGCGTTTCGCGGATATAATTATGCCTTGAACGAGATCGCCGTGCTGAAGCGTGATAGTTCCTCGATGATTACGATT
CATACATTCTTGAATGGGGAATATCTGACTTCTTATCAGGCGGATGGTTTGGTAGTGGCTACACCTACCGGTTCCACGGC
CTATTCGATGAGCGTAAATGGGCCGATTATCGTCCCGCAAAGTAATAGCATTGTCTTGAGTCCGGTCGCTCCGCATTCCT
TGAACGTGCGTCCGTTGGTGATTCCGGATTCAGATATAATAACGCTTCGGGTAGAGAGCCGGAATAAATATTTTCTGATC
TCTTTGGATGGACGTTCGGAAATATTCCCGGCAGGTATCGAATTAAAGATGAGCAAGGCCGATTATACGACGAAAGTCAT
CAAGCGCTATAACCATACTTTTTATCAGACGCTTCGGGAAAAATTAATGTGGGGGGCAGATGTGCGAATGAAATAA

Upstream 100 bases:

>100_bases
GCTTTATCATTTTATGGAGAAGGGGATGGTGGATGATATGTTGCGGCAGCGGATGAATGAGTTATTACATTATATGAATA
TGTAAAGTAAGGAGCGTAGA

Downstream 100 bases:

>100_bases
TATTGTGTGCGTCCAGTCTTTGTCCAAATAGTAGCGGATAGTATTGTATTTTGTAAGCTATTGATAAATAGATTATTCTG
CATGAATGAACTGAACGTAT

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MKVGIFGSEYQIERQNLIKRLFEKLREQEADIYVDSPFYTFLTDAFGFEPVVSGLLVGDEFDLDIALSVGGDGTFLRTAA
RVNKQDIPILGINTGRLGFLADVSSNEVEDTLDEIFKNYYKVEERTLLRLYTEDRAFRGYNYALNEIAVLKRDSSSMITI
HTFLNGEYLTSYQADGLVVATPTGSTAYSMSVNGPIIVPQSNSIVLSPVAPHSLNVRPLVIPDSDIITLRVESRNKYFLI
SLDGRSEIFPAGIELKMSKADYTTKVIKRYNHTFYQTLREKLMWGADVRMK

Sequences:

>Translated_291_residues
MKVGIFGSEYQIERQNLIKRLFEKLREQEADIYVDSPFYTFLTDAFGFEPVVSGLLVGDEFDLDIALSVGGDGTFLRTAA
RVNKQDIPILGINTGRLGFLADVSSNEVEDTLDEIFKNYYKVEERTLLRLYTEDRAFRGYNYALNEIAVLKRDSSSMITI
HTFLNGEYLTSYQADGLVVATPTGSTAYSMSVNGPIIVPQSNSIVLSPVAPHSLNVRPLVIPDSDIITLRVESRNKYFLI
SLDGRSEIFPAGIELKMSKADYTTKVIKRYNHTFYQTLREKLMWGADVRMK
>Mature_291_residues
MKVGIFGSEYQIERQNLIKRLFEKLREQEADIYVDSPFYTFLTDAFGFEPVVSGLLVGDEFDLDIALSVGGDGTFLRTAA
RVNKQDIPILGINTGRLGFLADVSSNEVEDTLDEIFKNYYKVEERTLLRLYTEDRAFRGYNYALNEIAVLKRDSSSMITI
HTFLNGEYLTSYQADGLVVATPTGSTAYSMSVNGPIIVPQSNSIVLSPVAPHSLNVRPLVIPDSDIITLRVESRNKYFLI
SLDGRSEIFPAGIELKMSKADYTTKVIKRYNHTFYQTLREKLMWGADVRMK

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=262, Percent_Identity=27.0992366412214, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1788968, Length=224, Percent_Identity=35.2678571428571, Blast_Score=144, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI71999610, Length=144, Percent_Identity=29.8611111111111, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320794, Length=242, Percent_Identity=28.9256198347107, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6325068, Length=203, Percent_Identity=33.9901477832512, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6322509, Length=251, Percent_Identity=26.6932270916335, Blast_Score=109, Evalue=5e-25,
Organism=Drosophila melanogaster, GI28573828, Length=254, Percent_Identity=29.9212598425197, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI28573826, Length=254, Percent_Identity=29.9212598425197, Blast_Score=104, Evalue=8e-23,
Organism=Drosophila melanogaster, GI28573832, Length=254, Percent_Identity=29.9212598425197, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI28573830, Length=254, Percent_Identity=29.9212598425197, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI161077047, Length=254, Percent_Identity=29.9212598425197, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI281363321, Length=278, Percent_Identity=26.2589928057554, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24653424, Length=278, Percent_Identity=26.2589928057554, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281363323, Length=278, Percent_Identity=26.2589928057554, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI20129957, Length=278, Percent_Identity=26.2589928057554, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24653422, Length=278, Percent_Identity=26.2589928057554, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 32876; Mature: 32876

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVGIFGSEYQIERQNLIKRLFEKLREQEADIYVDSPFYTFLTDAFGFEPVVSGLLVGDE
CEEEECCCCEEEHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHCCHHHHHHHEEECCC
FDLDIALSVGGDGTFLRTAARVNKQDIPILGINTGRLGFLADVSSNEVEDTLDEIFKNYY
CCEEEEEEECCCCCEEEHHHHCCCCCCCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHH
KVEERTLLRLYTEDRAFRGYNYALNEIAVLKRDSSSMITIHTFLNGEYLTSYQADGLVVA
HHHHHEEEEEEECCCCCCCCCHHHCEEEEEEECCCCEEEEEEEECCCEEEEECCCCEEEE
TPTGSTAYSMSVNGPIIVPQSNSIVLSPVAPHSLNVRPLVIPDSDIITLRVESRNKYFLI
CCCCCEEEEEECCCCEEEECCCCEEEECCCCCCCCEEEEEECCCCEEEEEEECCCCEEEE
SLDGRSEIFPAGIELKMSKADYTTKVIKRYNHTFYQTLREKLMWGADVRMK
EECCCCCEECCCEEEEECCCHHHHHHHHHHCHHHHHHHHHHHHCCCCEECC
>Mature Secondary Structure
MKVGIFGSEYQIERQNLIKRLFEKLREQEADIYVDSPFYTFLTDAFGFEPVVSGLLVGDE
CEEEECCCCEEEHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHCCHHHHHHHEEECCC
FDLDIALSVGGDGTFLRTAARVNKQDIPILGINTGRLGFLADVSSNEVEDTLDEIFKNYY
CCEEEEEEECCCCCEEEHHHHCCCCCCCEEEECCCCEEEEEECCCCHHHHHHHHHHHHHH
KVEERTLLRLYTEDRAFRGYNYALNEIAVLKRDSSSMITIHTFLNGEYLTSYQADGLVVA
HHHHHEEEEEEECCCCCCCCCHHHCEEEEEEECCCCEEEEEEEECCCEEEEECCCCEEEE
TPTGSTAYSMSVNGPIIVPQSNSIVLSPVAPHSLNVRPLVIPDSDIITLRVESRNKYFLI
CCCCCEEEEEECCCCEEEECCCCEEEECCCCCCCCEEEEEECCCCEEEEEEECCCCEEEE
SLDGRSEIFPAGIELKMSKADYTTKVIKRYNHTFYQTLREKLMWGADVRMK
EECCCCCEECCCEEEEECCCHHHHHHHHHHCHHHHHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]