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The map label for this gene is udg [H]

Identifier: 150008099

GI number: 150008099

Start: 1703999

End: 1705315

Strand: Reverse

Name: udg [H]

Synonym: BDI_1463

Alternate gene names: 150008099

Gene position: 1705315-1703999 (Counterclockwise)

Preceding gene: 150008103

Following gene: 150008096

Centisome position: 35.44

GC content: 43.51

Gene sequence:

>1317_bases
ATGAAAATAGCGATTGTAGGTACAGGCTATGTCGGGTTGGTAACGGGTACTTGTTTTGCGGAAATGGGGACTGAGGTCTT
TTGTGTGGACGTGGATAAGGTAAAGATTGAGAATCTAAAGAAAGGCATAGTTCCTATCTATGAACCGGGGCTAGACGAGA
TGGTGGCACGCAATTCCCAAGCTGGTCGTCTTCATTTTATGACTGATTTAAAAGAATGTTTGAATGAGGTCGAGGTACTG
TTTTGTGCGGTTGGTACACCTCCCGATGAGGATGGTAGCGCAGACTTGAAGTATGTGCTTGAGGTTGCCCGTACGGTAGG
ACGCTATATGAATAAATATATCTTGGTTGTTACGAAAAGTACGGTTCCGGTAGGCACTGCCCAGAAAATCAAGAAAGCGA
TCAAGGAGGAACAAGCCTTGCGAGATGTGAGTATTGAATTTGATATCGCTTCTAATCCTGAATTCTTGAAAGAAGGTGCG
GCTATCAAGGATTTTATGAGTCCAGACCGGGTTGTTGTTGGGGTTGAGTCTGATCGTGCTCAGAAGTTGATGGCGAAATT
GTATCGTCCTTTTTTGTTAAATAATTTCCGTGTAATCTTCATGGATGTGCCATCTGCGGAGATGACAAAATATGCGGCGA
ACGCTATGTTGGCTACTCGCATCAGTTTTATGAATGATATTGCCAATTTGTGTGAGATAGTTGGGGCGGATGTTAATATG
GTACGTAAAGGAATCGGTACGGATGCCCGTATAGGTAGTCGTTTCTTATATGCGGGTTGTGGATACGGTGGGTCTTGTTT
TCCTAAAGACGTTAAGGCGCTTGTGAAGACCGCAGCCAACAGTGGTTACCAAATGCGTATCCTAGAAGCGGTGGAAGCCG
TAAACGAGGAGCAGAAATCGATATTGTTCCGTAAATTAATGAAACATTTTAGAGGAGATATACAAGGTAAGCGAATTGCT
TTATGGGGATTGGCATTTAAGCCGGAAACGGATGATATGCGAGAGGCTCCTTCGCTAGTCTTAATCAAAAAGTTGAAAGA
AGCCGGATGTGTAATTTCCGCCTATGATCCGGTTGCAATGCCCGAGGCTCAAAGACGTTTACCTGTGGGGGTGATTTCAT
ATGGTAAAGATATTTATGAGACCGTGATAGATGCAGACGCTCTGTTGCTTGTTACGGAATGGAAAGAATTTCGTATGCCC
TCCTGGTCTGTTATCAAGAAATTGATGTCCACGCCTTTAATTTTAGACGGACGTAATATTTATGACAAGACAGAGTTAGA
GGAAACCGGCTTTATCTATCATTGTATAGGTCGGTAA

Upstream 100 bases:

>100_bases
GCTTATGCCAAAAAAGCTTCCAAAGTTATGTATAATTCTTGAAATAGTCTTACTTTTGTATCTCTTTTAAATGCACTATA
AACATAAGTAATAGATATAT

Downstream 100 bases:

>100_bases
ATTTTAATTATACGAGATTGTATGAATCTCCGGATAGTTACAATCATTAGAAGGTTTATAGGCACCGAAATAGGTGATGT
AAATCTTCTTTTCTTTTGTA

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MKIAIVGTGYVGLVTGTCFAEMGTEVFCVDVDKVKIENLKKGIVPIYEPGLDEMVARNSQAGRLHFMTDLKECLNEVEVL
FCAVGTPPDEDGSADLKYVLEVARTVGRYMNKYILVVTKSTVPVGTAQKIKKAIKEEQALRDVSIEFDIASNPEFLKEGA
AIKDFMSPDRVVVGVESDRAQKLMAKLYRPFLLNNFRVIFMDVPSAEMTKYAANAMLATRISFMNDIANLCEIVGADVNM
VRKGIGTDARIGSRFLYAGCGYGGSCFPKDVKALVKTAANSGYQMRILEAVEAVNEEQKSILFRKLMKHFRGDIQGKRIA
LWGLAFKPETDDMREAPSLVLIKKLKEAGCVISAYDPVAMPEAQRRLPVGVISYGKDIYETVIDADALLLVTEWKEFRMP
SWSVIKKLMSTPLILDGRNIYDKTELEETGFIYHCIGR

Sequences:

>Translated_438_residues
MKIAIVGTGYVGLVTGTCFAEMGTEVFCVDVDKVKIENLKKGIVPIYEPGLDEMVARNSQAGRLHFMTDLKECLNEVEVL
FCAVGTPPDEDGSADLKYVLEVARTVGRYMNKYILVVTKSTVPVGTAQKIKKAIKEEQALRDVSIEFDIASNPEFLKEGA
AIKDFMSPDRVVVGVESDRAQKLMAKLYRPFLLNNFRVIFMDVPSAEMTKYAANAMLATRISFMNDIANLCEIVGADVNM
VRKGIGTDARIGSRFLYAGCGYGGSCFPKDVKALVKTAANSGYQMRILEAVEAVNEEQKSILFRKLMKHFRGDIQGKRIA
LWGLAFKPETDDMREAPSLVLIKKLKEAGCVISAYDPVAMPEAQRRLPVGVISYGKDIYETVIDADALLLVTEWKEFRMP
SWSVIKKLMSTPLILDGRNIYDKTELEETGFIYHCIGR
>Mature_438_residues
MKIAIVGTGYVGLVTGTCFAEMGTEVFCVDVDKVKIENLKKGIVPIYEPGLDEMVARNSQAGRLHFMTDLKECLNEVEVL
FCAVGTPPDEDGSADLKYVLEVARTVGRYMNKYILVVTKSTVPVGTAQKIKKAIKEEQALRDVSIEFDIASNPEFLKEGA
AIKDFMSPDRVVVGVESDRAQKLMAKLYRPFLLNNFRVIFMDVPSAEMTKYAANAMLATRISFMNDIANLCEIVGADVNM
VRKGIGTDARIGSRFLYAGCGYGGSCFPKDVKALVKTAANSGYQMRILEAVEAVNEEQKSILFRKLMKHFRGDIQGKRIA
LWGLAFKPETDDMREAPSLVLIKKLKEAGCVISAYDPVAMPEAQRRLPVGVISYGKDIYETVIDADALLLVTEWKEFRMP
SWSVIKKLMSTPLILDGRNIYDKTELEETGFIYHCIGR

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=465, Percent_Identity=35.9139784946237, Blast_Score=252, Evalue=4e-67,
Organism=Homo sapiens, GI296040438, Length=366, Percent_Identity=36.3387978142077, Blast_Score=204, Evalue=9e-53,
Organism=Homo sapiens, GI296040443, Length=324, Percent_Identity=35.8024691358025, Blast_Score=179, Evalue=4e-45,
Organism=Escherichia coli, GI1788340, Length=363, Percent_Identity=28.6501377410468, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI48994968, Length=422, Percent_Identity=26.303317535545, Blast_Score=122, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17560350, Length=460, Percent_Identity=36.0869565217391, Blast_Score=258, Evalue=6e-69,
Organism=Drosophila melanogaster, GI17136908, Length=468, Percent_Identity=35.042735042735, Blast_Score=254, Evalue=9e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 48700; Mature: 48700

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIVGTGYVGLVTGTCFAEMGTEVFCVDVDKVKIENLKKGIVPIYEPGLDEMVARNSQ
CEEEEEECCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCCCCCCCHHHHHHCCCC
AGRLHFMTDLKECLNEVEVLFCAVGTPPDEDGSADLKYVLEVARTVGRYMNKYILVVTKS
CCEEEHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEC
TVPVGTAQKIKKAIKEEQALRDVSIEFDIASNPEFLKEGAAIKDFMSPDRVVVGVESDRA
CCCCCCHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHCCCHHHHHCCCCCEEEECCCHHH
QKLMAKLYRPFLLNNFRVIFMDVPSAEMTKYAANAMLATRISFMNDIANLCEIVGADVNM
HHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRKGIGTDARIGSRFLYAGCGYGGSCFPKDVKALVKTAANSGYQMRILEAVEAVNEEQKS
HHHCCCCCHHHCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHCHHHHH
ILFRKLMKHFRGDIQGKRIALWGLAFKPETDDMREAPSLVLIKKLKEAGCVISAYDPVAM
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHHCCCEEEECCCCCC
PEAQRRLPVGVISYGKDIYETVIDADALLLVTEWKEFRMPSWSVIKKLMSTPLILDGRNI
CCHHHCCCCHHHHHCHHHHHHHHCCCCEEEEECHHHHCCCCHHHHHHHHCCCEEEECCCC
YDKTELEETGFIYHCIGR
CCCCCHHHCCEEEEECCC
>Mature Secondary Structure
MKIAIVGTGYVGLVTGTCFAEMGTEVFCVDVDKVKIENLKKGIVPIYEPGLDEMVARNSQ
CEEEEEECCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCCCCCCCHHHHHHCCCC
AGRLHFMTDLKECLNEVEVLFCAVGTPPDEDGSADLKYVLEVARTVGRYMNKYILVVTKS
CCEEEHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEC
TVPVGTAQKIKKAIKEEQALRDVSIEFDIASNPEFLKEGAAIKDFMSPDRVVVGVESDRA
CCCCCCHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHCCCHHHHHCCCCCEEEECCCHHH
QKLMAKLYRPFLLNNFRVIFMDVPSAEMTKYAANAMLATRISFMNDIANLCEIVGADVNM
HHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRKGIGTDARIGSRFLYAGCGYGGSCFPKDVKALVKTAANSGYQMRILEAVEAVNEEQKS
HHHCCCCCHHHCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEHHHHHHHHHCHHHHH
ILFRKLMKHFRGDIQGKRIALWGLAFKPETDDMREAPSLVLIKKLKEAGCVISAYDPVAM
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHHCCCEEEECCCCCC
PEAQRRLPVGVISYGKDIYETVIDADALLLVTEWKEFRMPSWSVIKKLMSTPLILDGRNI
CCHHHCCCCHHHHHCHHHHHHHHCCCCEEEEECHHHHCCCCHHHHHHHHCCCEEEECCCC
YDKTELEETGFIYHCIGR
CCCCCHHHCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]