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The map label for this gene is rcsC [H]

Identifier: 150008085

GI number: 150008085

Start: 1687462

End: 1689747

Strand: Reverse

Name: rcsC [H]

Synonym: BDI_1449

Alternate gene names: 150008085

Gene position: 1689747-1687462 (Counterclockwise)

Preceding gene: 150008095

Following gene: 150008084

Centisome position: 35.12

GC content: 43.39

Gene sequence:

>2286_bases
ATGAGATTTTTAAATTATGCCGGGGGTGTTTTTATTCTGCTCTTATTGGCGTTGGGGTGCAAACCCGAGGCGAAGCGGAG
CCGTGTGCTTGTGATCCAATCTTTTCGGTGGGATGACAAGAACTATCTGGAATTAAACTCGGATATCCGGAAAGAACTGA
GAAAAAACCGGGTGAATGCGGACATCCGCACGTTTTATCTCGATTGTGAGTGCTATATGGCTGAGGAGGAAGAGGAACGG
ATGTATAACTTTATCGATACGATACGTCTTTGGAAGCCCGACATCATATTGGTGAATGATGATCAGGCTACCTATACGTT
GATGAAATGCGGCCATCCTTTTGTAAAGAAAGTTCCGGTTGTTTTCTCTGGCGTCAATTTCCCTAATTGGGATTTGCTGG
AAAAATATCCGAACGTAACAGGTAGTTGGGACAAGATTGATTATAAGGAAAACCTTCGTTTGATCGATCAGCAAATGGGA
AAGTCTCGCATTTATATCAATTATGATAAGACCTCCTTAGGGCAGTTGGCTTTCCGGGAGTTGATAAAAGCGGTCGATAC
GAGCCGATATGTATTGAATTATAATCAATTGGCTTTCCAATTAAATGACCCGGACTTTAAGGTAGATTCCATGACGTTTA
GAACCGAGATGAGAATGAAGGCGATACGTCCTTCGAAAAATGTAATTCATTTCATGCCTTTTCGTAAAGCCAATGGGGAG
TTTTTATTGAGTAATATTAATGGTACCTATCCTTATTGCGTATTTTTCAATATCCGTTATGACTATACATCCGCAGGTTT
GTCTAAGATGTTCGTGACTCCTTCATTTACGGCGGTGCGGGAAATCTTTAATATAAACGTGGAAGTTCTGGGAGGCTATT
TTTGCTCGAATCGCATACAAGCGGCGGAACAGGCTCGGTTGGCGGCTAAAATTCTTTCCGGTACGCCTGTCTCTTCCGTT
CCGATCGTAGAGAGTCCTAAAGAGTATCTGTATGATTGGGGGGAGATGCAACGTTTAGGTATCTCAAAGGAGGAGGTCCC
TACTAATGTTCACATCATCAATATGCCTATTTCTGAACGGTATAAGATTGGGGTTTTTATCGCCTCTTCCTTGGGCGTGA
TCTTATTGCTGGCATTGATCGGTTATTTGTTTTATCTCTATTGGCGGGAAGCAAGACGAAGGAAAGCGGTGCTCGCTAAT
TTAAAGCAAGAGAAGGAGCATCTTTCTTTAGCGTTGGAAGGGGGGAATATATTCGCTTGGAAATTACAGTCTGGTACCTT
CCGGTTTGACAACGAGTTCTTTAGCTATGTGAATATTTCTCCCCGGGAAATTCCTTTGGATGAGCTGTACGAGATGACTC
ATCCGGACGATAGGCAGAGTTTGCGCTCCTTGATTGATTTCATTTGTACGGGTACGATCTCTCATCATATCCTTCAATAT
CGTTGCGATTTTAACGGGAAAGGTTACCAATGGTGGGAATTTCGTTACGGAAGCTTAGAGGATGCGAATGATGGGTATGT
AATCAATGGCTTATGTTTGAATATCCAAAATATCAAGGATACGGAGGAGGTCTTGATCTCTGCGAGGGAAAAAGCCGAGG
AGTCGGATCGGATGAAGTCGGCTTTCTTGGCGAATATGAGCCATGAGATCCGTACGCCGCTGAATGCGATTGTCGGTTTC
TCGAATTTAATGAACTCGGAAGAGGTCTTGGAGCCGGAAGAGCGTGAGCAGTTCGTGAAGTTGATTAATACGAACTCCGA
CTTACTATTGAAACTGATCAATGATATTTTAGATCTTTCCCGTATGGAATCCGGAAAGATGAGTTTTGTTTTCGATCGCC
ATGATTTGAATGTCTTGATCAATGAAATCTATTGTACTTTCCAGTTGATGATGCCCGAGGGGGTAGAGCTACGCATGCGT
GTCCCCGAGATCCCGGTGGTTGTGGCGGTAGATCCTTATCGGCTGAAACAAGTATTGTCTAATTTTATCAATAATGCCAT
CAAGTTCACGACTTCGGGCTATATAGAAGTGGGATACTATTTCTGTACGAAAGGCGACTGCCTTCATATCTATGTAGAAG
ACACTGGTATCGGTATCCCTGAGGAGAAACAGAAGCAAGTTTTTGATCGTTTTTGCAAATTGGATGAGTTTGCGCAAGGC
ACCGGACTCGGACTGGCGATTTGCCAAGTGATAGCGCAGCGTTTCGGCGGTGAGATACAATTGAAGTCGGAATATGGTAA
AGGTAGCCGTTTTATGCTAACTTTGCCTAAAGAACGTATAGGTTGA

Upstream 100 bases:

>100_bases
TTCATTTTAGAAGGGATGAAAGGAAAGAAAGATACAGCTAATGAATGTGAATACTGAAAATAGTCGTACTTTTGTCACAT
TTACTGTTTAAAGTTTGGAC

Downstream 100 bases:

>100_bases
CAAAGCATGGAACAAATAGAGGAACTTTCACGATTTATCAAGGAACATGCGTCGGATGATTTGAATCGTCTGTTGCTTTC
CGCCTCTCGTTATCCGGGGA

Product: putative two-component regulator sensor kinase

Products: NA

Alternate protein names: Capsular synthesis regulator component C [H]

Number of amino acids: Translated: 761; Mature: 761

Protein sequence:

>761_residues
MRFLNYAGGVFILLLLALGCKPEAKRSRVLVIQSFRWDDKNYLELNSDIRKELRKNRVNADIRTFYLDCECYMAEEEEER
MYNFIDTIRLWKPDIILVNDDQATYTLMKCGHPFVKKVPVVFSGVNFPNWDLLEKYPNVTGSWDKIDYKENLRLIDQQMG
KSRIYINYDKTSLGQLAFRELIKAVDTSRYVLNYNQLAFQLNDPDFKVDSMTFRTEMRMKAIRPSKNVIHFMPFRKANGE
FLLSNINGTYPYCVFFNIRYDYTSAGLSKMFVTPSFTAVREIFNINVEVLGGYFCSNRIQAAEQARLAAKILSGTPVSSV
PIVESPKEYLYDWGEMQRLGISKEEVPTNVHIINMPISERYKIGVFIASSLGVILLLALIGYLFYLYWREARRRKAVLAN
LKQEKEHLSLALEGGNIFAWKLQSGTFRFDNEFFSYVNISPREIPLDELYEMTHPDDRQSLRSLIDFICTGTISHHILQY
RCDFNGKGYQWWEFRYGSLEDANDGYVINGLCLNIQNIKDTEEVLISAREKAEESDRMKSAFLANMSHEIRTPLNAIVGF
SNLMNSEEVLEPEEREQFVKLINTNSDLLLKLINDILDLSRMESGKMSFVFDRHDLNVLINEIYCTFQLMMPEGVELRMR
VPEIPVVVAVDPYRLKQVLSNFINNAIKFTTSGYIEVGYYFCTKGDCLHIYVEDTGIGIPEEKQKQVFDRFCKLDEFAQG
TGLGLAICQVIAQRFGGEIQLKSEYGKGSRFMLTLPKERIG

Sequences:

>Translated_761_residues
MRFLNYAGGVFILLLLALGCKPEAKRSRVLVIQSFRWDDKNYLELNSDIRKELRKNRVNADIRTFYLDCECYMAEEEEER
MYNFIDTIRLWKPDIILVNDDQATYTLMKCGHPFVKKVPVVFSGVNFPNWDLLEKYPNVTGSWDKIDYKENLRLIDQQMG
KSRIYINYDKTSLGQLAFRELIKAVDTSRYVLNYNQLAFQLNDPDFKVDSMTFRTEMRMKAIRPSKNVIHFMPFRKANGE
FLLSNINGTYPYCVFFNIRYDYTSAGLSKMFVTPSFTAVREIFNINVEVLGGYFCSNRIQAAEQARLAAKILSGTPVSSV
PIVESPKEYLYDWGEMQRLGISKEEVPTNVHIINMPISERYKIGVFIASSLGVILLLALIGYLFYLYWREARRRKAVLAN
LKQEKEHLSLALEGGNIFAWKLQSGTFRFDNEFFSYVNISPREIPLDELYEMTHPDDRQSLRSLIDFICTGTISHHILQY
RCDFNGKGYQWWEFRYGSLEDANDGYVINGLCLNIQNIKDTEEVLISAREKAEESDRMKSAFLANMSHEIRTPLNAIVGF
SNLMNSEEVLEPEEREQFVKLINTNSDLLLKLINDILDLSRMESGKMSFVFDRHDLNVLINEIYCTFQLMMPEGVELRMR
VPEIPVVVAVDPYRLKQVLSNFINNAIKFTTSGYIEVGYYFCTKGDCLHIYVEDTGIGIPEEKQKQVFDRFCKLDEFAQG
TGLGLAICQVIAQRFGGEIQLKSEYGKGSRFMLTLPKERIG
>Mature_761_residues
MRFLNYAGGVFILLLLALGCKPEAKRSRVLVIQSFRWDDKNYLELNSDIRKELRKNRVNADIRTFYLDCECYMAEEEEER
MYNFIDTIRLWKPDIILVNDDQATYTLMKCGHPFVKKVPVVFSGVNFPNWDLLEKYPNVTGSWDKIDYKENLRLIDQQMG
KSRIYINYDKTSLGQLAFRELIKAVDTSRYVLNYNQLAFQLNDPDFKVDSMTFRTEMRMKAIRPSKNVIHFMPFRKANGE
FLLSNINGTYPYCVFFNIRYDYTSAGLSKMFVTPSFTAVREIFNINVEVLGGYFCSNRIQAAEQARLAAKILSGTPVSSV
PIVESPKEYLYDWGEMQRLGISKEEVPTNVHIINMPISERYKIGVFIASSLGVILLLALIGYLFYLYWREARRRKAVLAN
LKQEKEHLSLALEGGNIFAWKLQSGTFRFDNEFFSYVNISPREIPLDELYEMTHPDDRQSLRSLIDFICTGTISHHILQY
RCDFNGKGYQWWEFRYGSLEDANDGYVINGLCLNIQNIKDTEEVLISAREKAEESDRMKSAFLANMSHEIRTPLNAIVGF
SNLMNSEEVLEPEEREQFVKLINTNSDLLLKLINDILDLSRMESGKMSFVFDRHDLNVLINEIYCTFQLMMPEGVELRMR
VPEIPVVVAVDPYRLKQVLSNFINNAIKFTTSGYIEVGYYFCTKGDCLHIYVEDTGIGIPEEKQKQVFDRFCKLDEFAQG
TGLGLAICQVIAQRFGGEIQLKSEYGKGSRFMLTLPKERIG

Specific function: Member of the two-component regulatory system RcsC/RcsB involved in the regulation of the expression of genes involved in colanic acid capsule synthesis. Together with RcsF, RcsC probably functions as a membrane-associated protein kinase that phosphorylat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=244, Percent_Identity=38.1147540983607, Blast_Score=157, Evalue=3e-39,
Organism=Escherichia coli, GI1789149, Length=248, Percent_Identity=36.2903225806452, Blast_Score=149, Evalue=5e-37,
Organism=Escherichia coli, GI48994928, Length=231, Percent_Identity=35.4978354978355, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1788713, Length=422, Percent_Identity=28.6729857819905, Blast_Score=136, Evalue=6e-33,
Organism=Escherichia coli, GI87081816, Length=242, Percent_Identity=35.5371900826446, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1786912, Length=245, Percent_Identity=27.3469387755102, Blast_Score=104, Evalue=3e-23,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=32.5688073394495, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI1786600, Length=247, Percent_Identity=25.9109311740891, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1786783, Length=240, Percent_Identity=30, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1790346, Length=220, Percent_Identity=30.4545454545455, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788549, Length=242, Percent_Identity=29.7520661157025, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI1790861, Length=268, Percent_Identity=26.865671641791, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788393, Length=236, Percent_Identity=26.271186440678, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87082128, Length=238, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=3e-15,
Organism=Escherichia coli, GI1787894, Length=222, Percent_Identity=26.1261261261261, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1789808, Length=227, Percent_Identity=28.1938325991189, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR004358
- InterPro:   IPR019017
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09456 RcsC; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88123; Mature: 88123

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLNYAGGVFILLLLALGCKPEAKRSRVLVIQSFRWDDKNYLELNSDIRKELRKNRVNA
CCCCHHCCHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCEEEECHHHHHHHHHCCCCC
DIRTFYLDCECYMAEEEEERMYNFIDTIRLWKPDIILVNDDQATYTLMKCGHPFVKKVPV
CEEEEEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCCEEEHHHCCCHHHHCCCC
VFSGVNFPNWDLLEKYPNVTGSWDKIDYKENLRLIDQQMGKSRIYINYDKTSLGQLAFRE
EEECCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHH
LIKAVDTSRYVLNYNQLAFQLNDPDFKVDSMTFRTEMRMKAIRPSKNVIHFMPFRKANGE
HHHHHCCCCEEEEEEEEEEEECCCCCEECCEEHHHHHHHHHCCCCCCEEEEECEECCCCC
FLLSNINGTYPYCVFFNIRYDYTSAGLSKMFVTPSFTAVREIFNINVEVLGGYFCSNRIQ
EEEECCCCCCEEEEEEEEEEEECCCCCEEEEECCCHHHHHHHHCCCEEEEECCHHHHHHH
AAEQARLAAKILSGTPVSSVPIVESPKEYLYDWGEMQRLGISKEEVPTNVHIINMPISER
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCHHHHHHCCCCHHHCCCEEEEEECCCCCC
YKIGVFIASSLGVILLLALIGYLFYLYWREARRRKAVLANLKQEKEHLSLALEGGNIFAW
EEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCEEEE
KLQSGTFRFDNEFFSYVNISPREIPLDELYEMTHPDDRQSLRSLIDFICTGTISHHILQY
EECCCCEEECCHHEEEECCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCEEEE
RCDFNGKGYQWWEFRYGSLEDANDGYVINGLCLNIQNIKDTEEVLISAREKAEESDRMKS
EECCCCCCEEEEEEECCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
AFLANMSHEIRTPLNAIVGFSNLMNSEEVLEPEEREQFVKLINTNSDLLLKLINDILDLS
HHHHHCCHHHHCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RMESGKMSFVFDRHDLNVLINEIYCTFQLMMPEGVELRMRVPEIPVVVAVDPYRLKQVLS
HCCCCCEEEEEECCCHHHHHHHHEEEEEEECCCCCEEEEECCCCCEEEEECHHHHHHHHH
NFINNAIKFTTSGYIEVGYYFCTKGDCLHIYVEDTGIGIPEEKQKQVFDRFCKLDEFAQG
HHHCCCEEEEECCEEEEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHCHHHHCCC
TGLGLAICQVIAQRFGGEIQLKSEYGKGSRFMLTLPKERIG
CCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCHHHCC
>Mature Secondary Structure
MRFLNYAGGVFILLLLALGCKPEAKRSRVLVIQSFRWDDKNYLELNSDIRKELRKNRVNA
CCCCHHCCHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCEEEECHHHHHHHHHCCCCC
DIRTFYLDCECYMAEEEEERMYNFIDTIRLWKPDIILVNDDQATYTLMKCGHPFVKKVPV
CEEEEEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCCEEEHHHCCCHHHHCCCC
VFSGVNFPNWDLLEKYPNVTGSWDKIDYKENLRLIDQQMGKSRIYINYDKTSLGQLAFRE
EEECCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHH
LIKAVDTSRYVLNYNQLAFQLNDPDFKVDSMTFRTEMRMKAIRPSKNVIHFMPFRKANGE
HHHHHCCCCEEEEEEEEEEEECCCCCEECCEEHHHHHHHHHCCCCCCEEEEECEECCCCC
FLLSNINGTYPYCVFFNIRYDYTSAGLSKMFVTPSFTAVREIFNINVEVLGGYFCSNRIQ
EEEECCCCCCEEEEEEEEEEEECCCCCEEEEECCCHHHHHHHHCCCEEEEECCHHHHHHH
AAEQARLAAKILSGTPVSSVPIVESPKEYLYDWGEMQRLGISKEEVPTNVHIINMPISER
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCHHHHHHCCCCHHHCCCEEEEEECCCCCC
YKIGVFIASSLGVILLLALIGYLFYLYWREARRRKAVLANLKQEKEHLSLALEGGNIFAW
EEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCEEEE
KLQSGTFRFDNEFFSYVNISPREIPLDELYEMTHPDDRQSLRSLIDFICTGTISHHILQY
EECCCCEEECCHHEEEECCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCEEEE
RCDFNGKGYQWWEFRYGSLEDANDGYVINGLCLNIQNIKDTEEVLISAREKAEESDRMKS
EECCCCCCEEEEEEECCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
AFLANMSHEIRTPLNAIVGFSNLMNSEEVLEPEEREQFVKLINTNSDLLLKLINDILDLS
HHHHHCCHHHHCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RMESGKMSFVFDRHDLNVLINEIYCTFQLMMPEGVELRMRVPEIPVVVAVDPYRLKQVLS
HCCCCCEEEEEECCCHHHHHHHHEEEEEEECCCCCEEEEECCCCCEEEEECHHHHHHHHH
NFINNAIKFTTSGYIEVGYYFCTKGDCLHIYVEDTGIGIPEEKQKQVFDRFCKLDEFAQG
HHHCCCEEEEECCEEEEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHCHHHHCCC
TGLGLAICQVIAQRFGGEIQLKSEYGKGSRFMLTLPKERIG
CCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2404948; 8366025; 9097040; 9278503; 11758943; 11309126; 13129944 [H]