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The map label for this gene is xasA [C]

Identifier: 150007570

GI number: 150007570

Start: 1061231

End: 1062718

Strand: Reverse

Name: xasA [C]

Synonym: BDI_0923

Alternate gene names: 150007570

Gene position: 1062718-1061231 (Counterclockwise)

Preceding gene: 150007576

Following gene: 150007569

Centisome position: 22.09

GC content: 42.67

Gene sequence:

>1488_bases
ATGGCAAATATCAACAAGACAGTAAAGCTAGGTGTGTTTACCCTAGCAATCATGAACGTGACGGCAGTAGTATCTTTACG
CGGACTGCCAGCAGAAGCCGTATACGGACTAAGTTCGGCTTTCTATTACTTATTCGCGGCAATCGTATTCTTAATCCCGA
CCTCTTTGGTGGCAGCGGAATTAGCGGCAATGTTCCAAGACAAACAAGGTGGTGTATTCCGTTGGGTAGGTGAGGCCTAT
GGAAAACGTCTAGGCTTTCTGGCTATCTGGGTTCAATGGATTGAAAGTACGATCTGGTATCCGACAGTATTAACTTTTGG
AGCCGTATCCATCGCCTTCATCGGTATGGATCATCCCGAAGATATGCTGCTGGCGAATAACAAATACTACACATTAGCGA
TCGTGTTAATTATTTATTGGCTGGCTACATTTATCTCACTAAAGGGATTGAGTTGGGTTGGAAAAGTAGCGAAAATCGGA
GGTATGGTAGGTACTATCATACCAGCGGCGTTACTCATCATTTTAGGTATCGTATACCTAGCGACTGGCGGGCATTCCAA
TATGGATTTCCACAGTAACTTCTTCCCCGACTTCAGTAAATTCGACAACTTAGTCTTAGCCGCAAGTATCTTCCTTTTTT
ACGCAGGTATGGAAATGGGCGGTATTCACGTGAAAGACGTTGACAATCCTTCTAAAAACTATCCGAAAGCTGTATTTATC
GGTGCCTTGATCACCGTTGTAATCTTCGTACTAGGAACTTTTGCGTTGGGTATTATTATCCCAGAGAAAGACATCAATCT
TACGCAAAGTTTATTAGTGGGATTCGACAATTACTTCAAGTACATTCATGCCTCATGGTTATCCCCAATTATCGCTATCG
CTTTGGCATTTGGCGTATTAGCAGGAGTATTGACATGGGTCGCTGGTCCTTCCAAAGGTATATTCGCAGTTGGTAAAGCA
GGTTATCTGCCCCCGTTCTTCCAGAAGACCAATAAGATCGGCGTACAGAAAAACATCCTTTATATCCAAGGAGCGGCTGT
TACACTTCTTAGCTTATTATTCGTGGTAATGCCATCCGTACAAAGCTTTTATCAGATCTTATCACAGCTTACGGTGATCT
TATATTTAATAATGTATATGTTGATGTTCTCCGGAGCGATCGCATTACGTTATAAGATGAAAAAGGCAGGTCGTCCTTTC
CGTATCGGAAAAGGTGGCAATGGCTTGATGTGGTTAATCGGAGGTTTAGGATTCTGTGGTTCCTTATTAGCGTTCGTATT
AAGTTTCATTCCTCCTAGCCAGATTTCTACAGGAAATAATACGGTTTGGTTCGCCGTTCTCTTCATCGGTGTAATTGTTG
TCGTTGCGGCACCGTTTATTATCTATGCGTCTAAGAAAGCATCTTGGGTAGATCCGAACACTGAATTCGAACCGTTCCAT
TGGGAAGTAAAAAATGACGTATCCGAGACGAATACGACAAAAGCATAA

Upstream 100 bases:

>100_bases
CCAAGTTTTACGTAGCAAAAACAAAACATCTTCTTTGATTCGCTGTTATAAACTCAGACTTAAACGAGAGAAGTAATTCT
CATTTTTAAAACATAAATCT

Downstream 100 bases:

>100_bases
CACACATTCATCTCGATAATTACCTAGTCCGGGCTGCGAAAATATTGCAGCTCGGACTTTTTCGTAAAAATAGCACAGAA
TATTTACGTTTTATTATGTG

Product: glutamate/gamma-aminobutyrate anti-porter

Products: L-glutamate [Cytoplasm]; 4-aminobutyrate [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MANINKTVKLGVFTLAIMNVTAVVSLRGLPAEAVYGLSSAFYYLFAAIVFLIPTSLVAAELAAMFQDKQGGVFRWVGEAY
GKRLGFLAIWVQWIESTIWYPTVLTFGAVSIAFIGMDHPEDMLLANNKYYTLAIVLIIYWLATFISLKGLSWVGKVAKIG
GMVGTIIPAALLIILGIVYLATGGHSNMDFHSNFFPDFSKFDNLVLAASIFLFYAGMEMGGIHVKDVDNPSKNYPKAVFI
GALITVVIFVLGTFALGIIIPEKDINLTQSLLVGFDNYFKYIHASWLSPIIAIALAFGVLAGVLTWVAGPSKGIFAVGKA
GYLPPFFQKTNKIGVQKNILYIQGAAVTLLSLLFVVMPSVQSFYQILSQLTVILYLIMYMLMFSGAIALRYKMKKAGRPF
RIGKGGNGLMWLIGGLGFCGSLLAFVLSFIPPSQISTGNNTVWFAVLFIGVIVVVAAPFIIYASKKASWVDPNTEFEPFH
WEVKNDVSETNTTKA

Sequences:

>Translated_495_residues
MANINKTVKLGVFTLAIMNVTAVVSLRGLPAEAVYGLSSAFYYLFAAIVFLIPTSLVAAELAAMFQDKQGGVFRWVGEAY
GKRLGFLAIWVQWIESTIWYPTVLTFGAVSIAFIGMDHPEDMLLANNKYYTLAIVLIIYWLATFISLKGLSWVGKVAKIG
GMVGTIIPAALLIILGIVYLATGGHSNMDFHSNFFPDFSKFDNLVLAASIFLFYAGMEMGGIHVKDVDNPSKNYPKAVFI
GALITVVIFVLGTFALGIIIPEKDINLTQSLLVGFDNYFKYIHASWLSPIIAIALAFGVLAGVLTWVAGPSKGIFAVGKA
GYLPPFFQKTNKIGVQKNILYIQGAAVTLLSLLFVVMPSVQSFYQILSQLTVILYLIMYMLMFSGAIALRYKMKKAGRPF
RIGKGGNGLMWLIGGLGFCGSLLAFVLSFIPPSQISTGNNTVWFAVLFIGVIVVVAAPFIIYASKKASWVDPNTEFEPFH
WEVKNDVSETNTTKA
>Mature_494_residues
ANINKTVKLGVFTLAIMNVTAVVSLRGLPAEAVYGLSSAFYYLFAAIVFLIPTSLVAAELAAMFQDKQGGVFRWVGEAYG
KRLGFLAIWVQWIESTIWYPTVLTFGAVSIAFIGMDHPEDMLLANNKYYTLAIVLIIYWLATFISLKGLSWVGKVAKIGG
MVGTIIPAALLIILGIVYLATGGHSNMDFHSNFFPDFSKFDNLVLAASIFLFYAGMEMGGIHVKDVDNPSKNYPKAVFIG
ALITVVIFVLGTFALGIIIPEKDINLTQSLLVGFDNYFKYIHASWLSPIIAIALAFGVLAGVLTWVAGPSKGIFAVGKAG
YLPPFFQKTNKIGVQKNILYIQGAAVTLLSLLFVVMPSVQSFYQILSQLTVILYLIMYMLMFSGAIALRYKMKKAGRPFR
IGKGGNGLMWLIGGLGFCGSLLAFVLSFIPPSQISTGNNTVWFAVLFIGVIVVVAAPFIIYASKKASWVDPNTEFEPFHW
EVKNDVSETNTTKA

Specific function: Probable Amino Acid Transporter. Involved In Extreme Acid Resistance. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787768, Length=486, Percent_Identity=29.2181069958848, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI87082380, Length=379, Percent_Identity=22.1635883905013, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87081798, Length=449, Percent_Identity=22.4944320712695, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI48994921, Length=416, Percent_Identity=19.4711538461538, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786908, Length=335, Percent_Identity=23.2835820895522, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45550968, Length=358, Percent_Identity=25.1396648044693, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI19921172, Length=358, Percent_Identity=25.1396648044693, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 54054; Mature: 53923

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANINKTVKLGVFTLAIMNVTAVVSLRGLPAEAVYGLSSAFYYLFAAIVFLIPTSLVAAE
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAMFQDKQGGVFRWVGEAYGKRLGFLAIWVQWIESTIWYPTVLTFGAVSIAFIGMDHPE
HHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCC
DMLLANNKYYTLAIVLIIYWLATFISLKGLSWVGKVAKIGGMVGTIIPAALLIILGIVYL
HHEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATGGHSNMDFHSNFFPDFSKFDNLVLAASIFLFYAGMEMGGIHVKDVDNPSKNYPKAVFI
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHH
GALITVVIFVLGTFALGIIIPEKDINLTQSLLVGFDNYFKYIHASWLSPIIAIALAFGVL
HHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGVLTWVAGPSKGIFAVGKAGYLPPFFQKTNKIGVQKNILYIQGAAVTLLSLLFVVMPSV
HHHHHHHCCCCCCEEEECCCCCCCHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHH
QSFYQILSQLTVILYLIMYMLMFSGAIALRYKMKKAGRPFRIGKGGNGLMWLIGGLGFCG
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHH
SLLAFVLSFIPPSQISTGNNTVWFAVLFIGVIVVVAAPFIIYASKKASWVDPNTEFEPFH
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCE
WEVKNDVSETNTTKA
EEHHCCCCCCCCCCC
>Mature Secondary Structure 
ANINKTVKLGVFTLAIMNVTAVVSLRGLPAEAVYGLSSAFYYLFAAIVFLIPTSLVAAE
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH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EEHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-aminobutyrate [Cytoplasm]; L-glutamate [Periplasm] [C]

Specific reaction: 4-aminobutyrate [Cytoplasm] + L-glutamate [Periplasm] = L-glutamate [Cytoplasm] + 4-aminobutyrate [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8366052 [H]