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The map label for this gene is ftsK [H]

Identifier: 150006115

GI number: 150006115

Start: 4489775

End: 4492240

Strand: Direct

Name: ftsK [H]

Synonym: BVU_3626

Alternate gene names: 150006115

Gene position: 4489775-4492240 (Clockwise)

Preceding gene: 150006111

Following gene: 150006116

Centisome position: 86.96

GC content: 44.65

Gene sequence:

>2466_bases
ATGGCAAAGAAAAAATCAGATAAGGAGACAGAGCCTAAAAAGGTATCTACCAAACGATTCTCCGCTTTTTTAAAGAACGA
AACCACACATTTTGTAATCGGATTGATCAGTGTAATTTTTGCAGTTTATCTGTTACTGGCATTTACCTCTTTCTTCTTTA
CGGGGGCCGCCGACCAAAGTATTTTGGATAATCAGCAGCCGGGTGAACTGATGCAAACCGCCAATCATGTAAAAAATTAC
GCCGGAGCACGCGGTGCACAACTTGCCGAATTCCTTATAAACGAATGTTTCGGCTTAGCTGCTTATTTTATCATTTTATT
CCTGGCCGTAGTGGGTATGAAATTAATGAAAGCTTACCAGTTCCGTATCTGGAAATGGTTTATGTCCTGTTCTATCCTGC
TCATCTGGTTCTCTATCACATTGGGATTTATTTTTGACGGCACCTTTGGGGATAGTTTTATCTATCCGGGGGGATTGCAC
GGACATAATGTAAGCAATTGGCTGATTTCACAAATTGGGATTCCAGGTTTGGGATTATTGCTGTTCATAGCGGCACTATT
GTTCTTTATCTATTTAAGTAACGAAACCATACTGGTTATCCGTAAAGCACTGCGTCCCAGCTTCAGACGAAAGAAAAAAG
AGGATCAAACAATTTCTGCGACTGAAGAAAATCCGATTAAAGAAGCTCCCCGGAAGGAAGAATCCAGGAAAGAATTCTCT
AATCCCGGTCCCGCTATCGTAGATTTCGAATTAGAACAACCGACAAAGAAAGAAGAGGAAGTGGAAGAACAAGTGCCCTT
CCCTTTTGAGAGCAAGCAGGTTACCGAACCGGCAGTGATAGAAGAACCTGCCTACACAAACGAAGAAGAGGAAGTTGAAA
ATACAGATGAACCTGATTTTTCAATCAGTGAAGAAACAAATGAAGAAGACGAGGCGTACAAAGGTCCCGTACTTCCACCA
TACAACCCTCGTCTGGATTTGGAAAACTACAAATTCCCTAGTTTGGATTTGCTAAATGAATATGAAGATGATGGTCCTAA
TATTGACATGGAAGAGCAAAACGCCAACAAAGACCGCATCATCAAGGTTTTACGTAGCTTCGGTATTGAAATCAGTTCCA
TCAAGGCAAGTGTAGGTCCTACCATCACATTATACGAAATTACTCCGGCAGAGGGGGTACGTATCTCTAAAATCAGGAAC
TTGGAAGATGATATCGCATTAAGTTTGTCGGCACTGGGTATCCGCATCATTGCTCCGATACCGGGCAAAGGCACTATCGG
TATTGAGGTTCCGAATGCCAATCCGCGCATTGTACCGATGAAATCCATCCTGAACAGCAAAAAGTTCCAAGAAACCACCT
ATGAGCTGCCTGTGGCATTAGGCAAGACCATTACGAACGAAGTCTTTATGGTGGACTTGGCAAAAGCCCCCCACATGTTG
GTAGCCGGCGCTACCGGACAGGGTAAGTCCGTAGGATTGAATGCCATCGTGACCTCTTTATTATATAAGAAGCATCCGGC
AGAACTTAAGTTTGTAATTGTAGACCCCAAGAAGGTGGAGTTCGCTATCTATGCTCCGATTGAGAAGCATTTTCTGGCCA
AGCTGCCGGATGGAGAAGACGCGATTATCACCGATGTTACCAAAGTGGTACAAACCTTGAACTCACTATGTATAGAGATG
GACAGCCGATACGACTTGCTGCGTAAAGCCGGTTGCCGTAATATTAAGGAATATAACGCGAAATTCATCAACCGGCAGTT
GAATCCGGAAAAAGGACACCGCTTCATGCCTTACATAGTGATTATCATTGATGAGTTCGGTGACCTGATTATGACTGCGG
GTAAGGAAGTGGAATTACCTATCTGCCGTATCGCCCAGTTGGCACGTGCAGTAGGCATACATGCCATTATCGCGACCCAG
CGTCCGACAACGAACATTATTACCGGTACTATCAAAGCTAACTTCCCGGCACGTGTTGCCTTCCGTGTAGCTGCCATGAT
GGACTCACGTACTATTCTGGACCGTTCGGGAGCACAGCAGCTGATTGGTAAGGGAGATATGCTTTACTTGCAAGGTAATG
ATCCGGTACGTGTGCAATGTGCATTCGTGGATACTCCTGAAGTGGAAAAAATAGCCAATTACATCAGTAAACAACAAGGA
TACACCACCGCATTCATGTTGCCCGAATATGTAGGCGAAGAGAGTGAAAGCAGCGTTGGCGAAGTAGACATGAACCGGTT
AGACCCTATGTTTGAAGACGCAGCCAGACTGGTCGTGATTCACCAGCAAGGCTCTACCTCATTAATCCAACGCAAGTTCT
CTATCGGCTATAACCGTGCGGGACGTATCATGGACCAACTGGAAAAAGCTGGAATTGTTGGCCCCACTCAAGGAAGCAAG
GCGCGTGACGTACTCTGCATGGATGAAACAGACCTGGAAATGAAATTGAACAATCTGCAACAATAA

Upstream 100 bases:

>100_bases
ATTAAAATTGAATCGCAAAGTTAAGAAAAAAGAGATTAAATAAGGCAATAATTAATGTTTTTCATGTACATTTGCGAAAT
AATAAATAGAACGAAGACCT

Downstream 100 bases:

>100_bases
GTTGTTTAATAATGTTATGATAAAAATGAAAAGAACATATTTACTGGTATTAATCCTTTTCCTTTCAGTCAGCCTATCCG
CACAAAAGGACAAACAGGCA

Product: FtsK/SpoIIIE family cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 821; Mature: 820

Protein sequence:

>821_residues
MAKKKSDKETEPKKVSTKRFSAFLKNETTHFVIGLISVIFAVYLLLAFTSFFFTGAADQSILDNQQPGELMQTANHVKNY
AGARGAQLAEFLINECFGLAAYFIILFLAVVGMKLMKAYQFRIWKWFMSCSILLIWFSITLGFIFDGTFGDSFIYPGGLH
GHNVSNWLISQIGIPGLGLLLFIAALLFFIYLSNETILVIRKALRPSFRRKKKEDQTISATEENPIKEAPRKEESRKEFS
NPGPAIVDFELEQPTKKEEEVEEQVPFPFESKQVTEPAVIEEPAYTNEEEEVENTDEPDFSISEETNEEDEAYKGPVLPP
YNPRLDLENYKFPSLDLLNEYEDDGPNIDMEEQNANKDRIIKVLRSFGIEISSIKASVGPTITLYEITPAEGVRISKIRN
LEDDIALSLSALGIRIIAPIPGKGTIGIEVPNANPRIVPMKSILNSKKFQETTYELPVALGKTITNEVFMVDLAKAPHML
VAGATGQGKSVGLNAIVTSLLYKKHPAELKFVIVDPKKVEFAIYAPIEKHFLAKLPDGEDAIITDVTKVVQTLNSLCIEM
DSRYDLLRKAGCRNIKEYNAKFINRQLNPEKGHRFMPYIVIIIDEFGDLIMTAGKEVELPICRIAQLARAVGIHAIIATQ
RPTTNIITGTIKANFPARVAFRVAAMMDSRTILDRSGAQQLIGKGDMLYLQGNDPVRVQCAFVDTPEVEKIANYISKQQG
YTTAFMLPEYVGEESESSVGEVDMNRLDPMFEDAARLVVIHQQGSTSLIQRKFSIGYNRAGRIMDQLEKAGIVGPTQGSK
ARDVLCMDETDLEMKLNNLQQ

Sequences:

>Translated_821_residues
MAKKKSDKETEPKKVSTKRFSAFLKNETTHFVIGLISVIFAVYLLLAFTSFFFTGAADQSILDNQQPGELMQTANHVKNY
AGARGAQLAEFLINECFGLAAYFIILFLAVVGMKLMKAYQFRIWKWFMSCSILLIWFSITLGFIFDGTFGDSFIYPGGLH
GHNVSNWLISQIGIPGLGLLLFIAALLFFIYLSNETILVIRKALRPSFRRKKKEDQTISATEENPIKEAPRKEESRKEFS
NPGPAIVDFELEQPTKKEEEVEEQVPFPFESKQVTEPAVIEEPAYTNEEEEVENTDEPDFSISEETNEEDEAYKGPVLPP
YNPRLDLENYKFPSLDLLNEYEDDGPNIDMEEQNANKDRIIKVLRSFGIEISSIKASVGPTITLYEITPAEGVRISKIRN
LEDDIALSLSALGIRIIAPIPGKGTIGIEVPNANPRIVPMKSILNSKKFQETTYELPVALGKTITNEVFMVDLAKAPHML
VAGATGQGKSVGLNAIVTSLLYKKHPAELKFVIVDPKKVEFAIYAPIEKHFLAKLPDGEDAIITDVTKVVQTLNSLCIEM
DSRYDLLRKAGCRNIKEYNAKFINRQLNPEKGHRFMPYIVIIIDEFGDLIMTAGKEVELPICRIAQLARAVGIHAIIATQ
RPTTNIITGTIKANFPARVAFRVAAMMDSRTILDRSGAQQLIGKGDMLYLQGNDPVRVQCAFVDTPEVEKIANYISKQQG
YTTAFMLPEYVGEESESSVGEVDMNRLDPMFEDAARLVVIHQQGSTSLIQRKFSIGYNRAGRIMDQLEKAGIVGPTQGSK
ARDVLCMDETDLEMKLNNLQQ
>Mature_820_residues
AKKKSDKETEPKKVSTKRFSAFLKNETTHFVIGLISVIFAVYLLLAFTSFFFTGAADQSILDNQQPGELMQTANHVKNYA
GARGAQLAEFLINECFGLAAYFIILFLAVVGMKLMKAYQFRIWKWFMSCSILLIWFSITLGFIFDGTFGDSFIYPGGLHG
HNVSNWLISQIGIPGLGLLLFIAALLFFIYLSNETILVIRKALRPSFRRKKKEDQTISATEENPIKEAPRKEESRKEFSN
PGPAIVDFELEQPTKKEEEVEEQVPFPFESKQVTEPAVIEEPAYTNEEEEVENTDEPDFSISEETNEEDEAYKGPVLPPY
NPRLDLENYKFPSLDLLNEYEDDGPNIDMEEQNANKDRIIKVLRSFGIEISSIKASVGPTITLYEITPAEGVRISKIRNL
EDDIALSLSALGIRIIAPIPGKGTIGIEVPNANPRIVPMKSILNSKKFQETTYELPVALGKTITNEVFMVDLAKAPHMLV
AGATGQGKSVGLNAIVTSLLYKKHPAELKFVIVDPKKVEFAIYAPIEKHFLAKLPDGEDAIITDVTKVVQTLNSLCIEMD
SRYDLLRKAGCRNIKEYNAKFINRQLNPEKGHRFMPYIVIIIDEFGDLIMTAGKEVELPICRIAQLARAVGIHAIIATQR
PTTNIITGTIKANFPARVAFRVAAMMDSRTILDRSGAQQLIGKGDMLYLQGNDPVRVQCAFVDTPEVEKIANYISKQQGY
TTAFMLPEYVGEESESSVGEVDMNRLDPMFEDAARLVVIHQQGSTSLIQRKFSIGYNRAGRIMDQLEKAGIVGPTQGSKA
RDVLCMDETDLEMKLNNLQQ

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=503, Percent_Identity=40.9542743538767, Blast_Score=350, Evalue=2e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 91836; Mature: 91705

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKKSDKETEPKKVSTKRFSAFLKNETTHFVIGLISVIFAVYLLLAFTSFFFTGAADQS
CCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ILDNQQPGELMQTANHVKNYAGARGAQLAEFLINECFGLAAYFIILFLAVVGMKLMKAYQ
HHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRIWKWFMSCSILLIWFSITLGFIFDGTFGDSFIYPGGLHGHNVSNWLISQIGIPGLGLL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHH
LFIAALLFFIYLSNETILVIRKALRPSFRRKKKEDQTISATEENPIKEAPRKEESRKEFS
HHHHHHHHHHHHCCCEEEEEHHHHCHHHHHHHCCCCCEECCCCCCHHCCCCCHHHHHHHC
NPGPAIVDFELEQPTKKEEEVEEQVPFPFESKQVTEPAVIEEPAYTNEEEEVENTDEPDF
CCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCC
SISEETNEEDEAYKGPVLPPYNPRLDLENYKFPSLDLLNEYEDDGPNIDMEEQNANKDRI
CCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHH
IKVLRSFGIEISSIKASVGPTITLYEITPAEGVRISKIRNLEDDIALSLSALGIRIIAPI
HHHHHHHCCEEEEEECCCCCEEEEEEECCCCCEEHHHHHCCCHHHHHHHHHCCEEEEECC
PGKGTIGIEVPNANPRIVPMKSILNSKKFQETTYELPVALGKTITNEVFMVDLAKAPHML
CCCCEEEEEECCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEE
VAGATGQGKSVGLNAIVTSLLYKKHPAELKFVIVDPKKVEFAIYAPIEKHFLAKLPDGED
EEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCHHHHHHHCCCCCCC
AIITDVTKVVQTLNSLCIEMDSRYDLLRKAGCRNIKEYNAKFINRQLNPEKGHRFMPYIV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEECCEEE
IIIDEFGDLIMTAGKEVELPICRIAQLARAVGIHAIIATQRPTTNIITGTIKANFPARVA
EEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCEEEEEEECCCCHHHH
FRVAAMMDSRTILDRSGAQQLIGKGDMLYLQGNDPVRVQCAFVDTPEVEKIANYISKQQG
HHHHHHHCCHHHHHCCCHHHHHCCCCEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHCC
YTTAFMLPEYVGEESESSVGEVDMNRLDPMFEDAARLVVIHQQGSTSLIQRKFSIGYNRA
CEEEEECHHHHCCCCCCCCCCCCHHHCCHHHHCCCEEEEEECCCCHHHHHHHHHCCCCHH
GRIMDQLEKAGIVGPTQGSKARDVLCMDETDLEMKLNNLQQ
HHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHCCCC
>Mature Secondary Structure 
AKKKSDKETEPKKVSTKRFSAFLKNETTHFVIGLISVIFAVYLLLAFTSFFFTGAADQS
CCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ILDNQQPGELMQTANHVKNYAGARGAQLAEFLINECFGLAAYFIILFLAVVGMKLMKAYQ
HHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FRIWKWFMSCSILLIWFSITLGFIFDGTFGDSFIYPGGLHGHNVSNWLISQIGIPGLGLL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHH
LFIAALLFFIYLSNETILVIRKALRPSFRRKKKEDQTISATEENPIKEAPRKEESRKEFS
HHHHHHHHHHHHCCCEEEEEHHHHCHHHHHHHCCCCCEECCCCCCHHCCCCCHHHHHHHC
NPGPAIVDFELEQPTKKEEEVEEQVPFPFESKQVTEPAVIEEPAYTNEEEEVENTDEPDF
CCCCEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCC
SISEETNEEDEAYKGPVLPPYNPRLDLENYKFPSLDLLNEYEDDGPNIDMEEQNANKDRI
CCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHH
IKVLRSFGIEISSIKASVGPTITLYEITPAEGVRISKIRNLEDDIALSLSALGIRIIAPI
HHHHHHHCCEEEEEECCCCCEEEEEEECCCCCEEHHHHHCCCHHHHHHHHHCCEEEEECC
PGKGTIGIEVPNANPRIVPMKSILNSKKFQETTYELPVALGKTITNEVFMVDLAKAPHML
CCCCEEEEEECCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEE
VAGATGQGKSVGLNAIVTSLLYKKHPAELKFVIVDPKKVEFAIYAPIEKHFLAKLPDGED
EEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEECCHHHHHHHCCCCCCC
AIITDVTKVVQTLNSLCIEMDSRYDLLRKAGCRNIKEYNAKFINRQLNPEKGHRFMPYIV
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCEECCEEE
IIIDEFGDLIMTAGKEVELPICRIAQLARAVGIHAIIATQRPTTNIITGTIKANFPARVA
EEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCEEEEEEECCCCHHHH
FRVAAMMDSRTILDRSGAQQLIGKGDMLYLQGNDPVRVQCAFVDTPEVEKIANYISKQQG
HHHHHHHCCHHHHHCCCHHHHHCCCCEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHCC
YTTAFMLPEYVGEESESSVGEVDMNRLDPMFEDAARLVVIHQQGSTSLIQRKFSIGYNRA
CEEEEECHHHHCCCCCCCCCCCCHHHCCHHHHCCCEEEEEECCCCHHHHHHHHHCCCCHH
GRIMDQLEKAGIVGPTQGSKARDVLCMDETDLEMKLNNLQQ
HHHHHHHHHCCCCCCCCCCCCCEEEEECCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]