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The map label for this gene is nqrA [H]

Identifier: 150005741

GI number: 150005741

Start: 4061539

End: 4062888

Strand: Direct

Name: nqrA [H]

Synonym: BVU_3234

Alternate gene names: 150005741

Gene position: 4061539-4062888 (Clockwise)

Preceding gene: 150005740

Following gene: 150005742

Centisome position: 78.66

GC content: 49.33

Gene sequence:

>1350_bases
ATGGCAAATGTGATTAAATTACACAAAGGCTTGAACATCAACCTGAAAGGGAAACCTGCTCAGGAGTTCTTTGACGTGAA
GCAGCCGGACATCTATGCGATAGTGCCCGATGATTTTCATGGCGTGACTCCTAAAGTCGTGGTCAAAGAACAGGAATATG
TGACGGCCGGGGGAACATTGTTTGTTGACAAGAACCACCCCGAAGTGAAGTTCGTATCTCCGGTAAGCGGTGTCGTTACC
AGCGTGGAGAGAGGCGAACGTCGTAAAGTCTTAAGCATCTCCATTGCAGCTGCAAAGGAGCAAGACTACGAAGAGTTTGG
AAAGAAGGATGTTTCGACTCTGACAGGCGAGCAGGTAAAAGCCGCCCTGCTGGAAGCCGGACTTTTTTCATTCATTATCC
AGCGCCCCTACATCGTGGTGGCTGACCCGAATGCCAAGCCGAAAGGCATCTTCGTTTCTGCATTTGACACTAACCCATTG
GCTGCTGATTTCGAATTTGTTCTGAAAGGCCAGGAAAAAGATTTCCAGACTGGTCTGGACGCACTGGCAAAGATGGCAAA
GACGTATCTGAATATCAGCGTAGAGCAGAAGAGCCCTGCACTGACCAACGCCAAAAATGTAACTGTAACTGCCTTCGACG
GTCCTAACCCCGCCGGAAACGTAGGCGTTCAGATTAACCACATCAGTCCTATCAACAAAGGCGAAACTGTTTGGACGCTC
CGTGCGGAAGAAGTGATCTTCATCGGACGCCTGTTCAACACAGGTCGCGTAGACCTTACCCGTACTATCGCCCTGACCGG
TTCGGAAGTGAAGAAACCGGCTTATTGCAAGCTGAAAGTAGGAGCCTTGCTGACAGATATTTTTGCAGGACGTGTGAACG
GAGGTAAAAACTTACGCTACATTAACGGTAACGTGCTGACCGGAACTTTGGTGAAGCCAAACGGATTCCTGGGTGCGCAC
GCTACAAGTCTTACTGTGATCCCCGAAGGGGATGACCGGCACGAATTCCTGGGCTTTATCATGCCGCGTACCGATCAGTA
CAGTGCCAACCGCAGTTATTTCAGCTGGTTGTGCGGTAACAAGGAATACACACTGGATGCCCGTATCAAAGGTGGCGAAC
GCCACATGATCATGTCCGGCGAGTATGACAAAGTATTCCCGATGAGCATTTTCCCCGAATATTTAATTAAAGCTATCATT
GCCGGCGATATTGACCGCATGGAAGCACTTGGTATTTACGAAGTGGCTCCCGAAGACTTCGCTGTATGTGAATTCGTTGA
CTCTTCCAAATTGGAATTGCAACGCATCGTGCGTCAGGGCTTGGACATGCTTCGCAAGGAAATGTGCTAA

Upstream 100 bases:

>100_bases
TACAGAATTTTTTCCATAATAAGCACCATTTCTTTCTTTTTTCACATTTTTTTTCTGTACTTTTGCGCTCAAATTTAAAA
ACCATTTTTTATAACCCAAT

Downstream 100 bases:

>100_bases
ATAATTAAAAACTAAGAATTAAAAGTTAATGAAAGCGTTAAGAAATTATCTCGACAAGATAAAGCCAAACTTTGAAGAGG
GCGGCAAACTCCACGCGTTT

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A [H]

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MANVIKLHKGLNINLKGKPAQEFFDVKQPDIYAIVPDDFHGVTPKVVVKEQEYVTAGGTLFVDKNHPEVKFVSPVSGVVT
SVERGERRKVLSISIAAAKEQDYEEFGKKDVSTLTGEQVKAALLEAGLFSFIIQRPYIVVADPNAKPKGIFVSAFDTNPL
AADFEFVLKGQEKDFQTGLDALAKMAKTYLNISVEQKSPALTNAKNVTVTAFDGPNPAGNVGVQINHISPINKGETVWTL
RAEEVIFIGRLFNTGRVDLTRTIALTGSEVKKPAYCKLKVGALLTDIFAGRVNGGKNLRYINGNVLTGTLVKPNGFLGAH
ATSLTVIPEGDDRHEFLGFIMPRTDQYSANRSYFSWLCGNKEYTLDARIKGGERHMIMSGEYDKVFPMSIFPEYLIKAII
AGDIDRMEALGIYEVAPEDFAVCEFVDSSKLELQRIVRQGLDMLRKEMC

Sequences:

>Translated_449_residues
MANVIKLHKGLNINLKGKPAQEFFDVKQPDIYAIVPDDFHGVTPKVVVKEQEYVTAGGTLFVDKNHPEVKFVSPVSGVVT
SVERGERRKVLSISIAAAKEQDYEEFGKKDVSTLTGEQVKAALLEAGLFSFIIQRPYIVVADPNAKPKGIFVSAFDTNPL
AADFEFVLKGQEKDFQTGLDALAKMAKTYLNISVEQKSPALTNAKNVTVTAFDGPNPAGNVGVQINHISPINKGETVWTL
RAEEVIFIGRLFNTGRVDLTRTIALTGSEVKKPAYCKLKVGALLTDIFAGRVNGGKNLRYINGNVLTGTLVKPNGFLGAH
ATSLTVIPEGDDRHEFLGFIMPRTDQYSANRSYFSWLCGNKEYTLDARIKGGERHMIMSGEYDKVFPMSIFPEYLIKAII
AGDIDRMEALGIYEVAPEDFAVCEFVDSSKLELQRIVRQGLDMLRKEMC
>Mature_448_residues
ANVIKLHKGLNINLKGKPAQEFFDVKQPDIYAIVPDDFHGVTPKVVVKEQEYVTAGGTLFVDKNHPEVKFVSPVSGVVTS
VERGERRKVLSISIAAAKEQDYEEFGKKDVSTLTGEQVKAALLEAGLFSFIIQRPYIVVADPNAKPKGIFVSAFDTNPLA
ADFEFVLKGQEKDFQTGLDALAKMAKTYLNISVEQKSPALTNAKNVTVTAFDGPNPAGNVGVQINHISPINKGETVWTLR
AEEVIFIGRLFNTGRVDLTRTIALTGSEVKKPAYCKLKVGALLTDIFAGRVNGGKNLRYINGNVLTGTLVKPNGFLGAHA
TSLTVIPEGDDRHEFLGFIMPRTDQYSANRSYFSWLCGNKEYTLDARIKGGERHMIMSGEYDKVFPMSIFPEYLIKAIIA
GDIDRMEALGIYEVAPEDFAVCEFVDSSKLELQRIVRQGLDMLRKEMC

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008703
- InterPro:   IPR022615 [H]

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB [H]

EC number: NA

Molecular weight: Translated: 49523; Mature: 49391

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANVIKLHKGLNINLKGKPAQEFFDVKQPDIYAIVPDDFHGVTPKVVVKEQEYVTAGGTL
CCCEEEECCCCEEEECCCCHHHHHCCCCCCEEEECCCCCCCCCCEEEEECCEEEEECCEE
FVDKNHPEVKFVSPVSGVVTSVERGERRKVLSISIAAAKEQDYEEFGKKDVSTLTGEQVK
EEECCCCCEEEECCHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHCHHHHH
AALLEAGLFSFIIQRPYIVVADPNAKPKGIFVSAFDTNPLAADFEFVLKGQEKDFQTGLD
HHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEEEECCCCCCCCEEEEEECCCCHHHHHHH
ALAKMAKTYLNISVEQKSPALTNAKNVTVTAFDGPNPAGNVGVQINHISPINKGETVWTL
HHHHHHHHHEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCEEEEE
RAEEVIFIGRLFNTGRVDLTRTIALTGSEVKKPAYCKLKVGALLTDIFAGRVNGGKNLRY
ECCCEEEEEEECCCCCEEEEEEEEECCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCEEEE
INGNVLTGTLVKPNGFLGAHATSLTVIPEGDDRHEFLGFIMPRTDQYSANRSYFSWLCGN
ECCCEEEEEEECCCCCEECCCEEEEEEECCCCCHHHHEEECCCCCCCCCCCCEEEEEECC
KEYTLDARIKGGERHMIMSGEYDKVFPMSIFPEYLIKAIIAGDIDRMEALGIYEVAPEDF
CEEEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHCEEEEECCCCC
AVCEFVDSSKLELQRIVRQGLDMLRKEMC
EEEEECCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ANVIKLHKGLNINLKGKPAQEFFDVKQPDIYAIVPDDFHGVTPKVVVKEQEYVTAGGTL
CCEEEECCCCEEEECCCCHHHHHCCCCCCEEEECCCCCCCCCCEEEEECCEEEEECCEE
FVDKNHPEVKFVSPVSGVVTSVERGERRKVLSISIAAAKEQDYEEFGKKDVSTLTGEQVK
EEECCCCCEEEECCHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHCHHHHH
AALLEAGLFSFIIQRPYIVVADPNAKPKGIFVSAFDTNPLAADFEFVLKGQEKDFQTGLD
HHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEEEECCCCCCCCEEEEEECCCCHHHHHHH
ALAKMAKTYLNISVEQKSPALTNAKNVTVTAFDGPNPAGNVGVQINHISPINKGETVWTL
HHHHHHHHHEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCEEEEE
RAEEVIFIGRLFNTGRVDLTRTIALTGSEVKKPAYCKLKVGALLTDIFAGRVNGGKNLRY
ECCCEEEEEEECCCCCEEEEEEEEECCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCEEEE
INGNVLTGTLVKPNGFLGAHATSLTVIPEGDDRHEFLGFIMPRTDQYSANRSYFSWLCGN
ECCCEEEEEEECCCCCEECCCEEEEEEECCCCCHHHHEEECCCCCCCCCCCCEEEEEECC
KEYTLDARIKGGERHMIMSGEYDKVFPMSIFPEYLIKAIIAGDIDRMEALGIYEVAPEDF
CEEEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHCEEEEECCCCC
AVCEFVDSSKLELQRIVRQGLDMLRKEMC
EEEEECCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA