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The map label for this gene is udg [H]

Identifier: 150005664

GI number: 150005664

Start: 3971963

End: 3973276

Strand: Direct

Name: udg [H]

Synonym: BVU_3154

Alternate gene names: 150005664

Gene position: 3971963-3973276 (Clockwise)

Preceding gene: 150005653

Following gene: 150005665

Centisome position: 76.93

GC content: 46.5

Gene sequence:

>1314_bases
ATGAATATAGCGATTGTAGGAACCGGGTATGTAGGACTTGTTACCGGAACATGTTTTGCCGAAACTGGCGTAGACGTAAC
TTGTGTAGATGTAAATGCGGATAAGATTGCTAATCTGCAACAGGGTATTATTCCTATTTATGAACCGGGATTGGAAGATA
TGGTCTTGCGTAATGTAAAGGCTGGACGTCTTCATTTCACCACCTCTTTAGAGAGTTGTCTGGACAATGTGGATATTGTG
TTCAGTGCTGTGGGTACTCCTCCCGATGAAGACGGAAGTGCCGATTTGCGTTATGTGCTTGAAGTTGCCAAGACGATTGG
TGCTAATATGAAGAAATACACCTTGGTCGTGACCAAGAGTACGGTGCCCGTGGGTACGGCCCGGAAAGTAAAAGCGGCTA
TCCGGGAGGAATTGGAGAAAAGAGGGGAGTCGATAGATTTCGATGTGGCTTCTAATCCGGAATTCTTGAAAGAAGGTAAT
GCTATCGATGACTTTATGAGTCCGGACCGTGTGGTAGTGGGCGTAGAGTCGGAAAGGGCTAAAAAACTGATGACCAAGCT
TTATAAACCTTTCATGCTGGTTAACTTCCGCGTTATCTTCATGGATATTCCTTCTGCCGAGATGACCAAGTATGCGGCAA
ACTCCATGTTGGCTACCCGTATCAGCTTTATGAACGATATTGCCAACTTGTGCGAACTGGTGGGAGCTGATGTAAATATG
GTACGTGACGGAATAGGTTCCGACAGTCGTATCGGGCGTAAGTTCTTGTATCCGGGATGCGGTTATGGTGGATCTTGTTT
CCCGAAAGATGTGAAGGCGTTGATTAAGACTGCCGAGCAGAATGGTTATTCCATGCAGGTGTTGAAAGCGGTGGAAGATG
TGAACGAGAATCAGAAAGGCATTTTGTTCGAGAAACTGGTAAAAGTATTCAATGGAGATTTGAAAGGCAAAACAGTGGCT
TTGTGGGGACTTGCATTCAAGCCCGGTACGGACGATATGCGTGAGGCTCCGGCTTTGGTACTTATTGAGAAATTGAAACA
GTCGGGTTGCAATGTCCGCGCATACGATCCTGCTGCTATGGATGAGTCCCGCCGCCGGATAGGAGAGTCGGTTTATTATG
CGCACGATATGTATGATGCGGCTCTTGATGCGGATGCGTTGATTCTGGTAACCGAGTGGAAAGAGTTCCGTCTTCCTACC
TGGGGAGTAATCAAGAAGGCGATGAAGCAGCCTGTAGTGCTTGACGGACGAAATATTTATGATGGTGACGAACTACAGGA
AATGGGGTTTGTTTATCATTGCATCGGTCGATAA

Upstream 100 bases:

>100_bases
TTATTCCGTTTCAGCGCAACTTTTATGGAAGAAAATAACAACTCACTCATAATTTATTGTAATTTTGCAGCGAAAAAGTT
AGACTAACGAATTAAATAAA

Downstream 100 bases:

>100_bases
ATAAAAAAATAGAGAGAATAACCATGTACAAACGTTTTTCGATAATAATGTTGGCTGTTGCGCTGTCTTCTTGTGGAACT
CCGCAACAAAAAGCATCCGC

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MNIAIVGTGYVGLVTGTCFAETGVDVTCVDVNADKIANLQQGIIPIYEPGLEDMVLRNVKAGRLHFTTSLESCLDNVDIV
FSAVGTPPDEDGSADLRYVLEVAKTIGANMKKYTLVVTKSTVPVGTARKVKAAIREELEKRGESIDFDVASNPEFLKEGN
AIDDFMSPDRVVVGVESERAKKLMTKLYKPFMLVNFRVIFMDIPSAEMTKYAANSMLATRISFMNDIANLCELVGADVNM
VRDGIGSDSRIGRKFLYPGCGYGGSCFPKDVKALIKTAEQNGYSMQVLKAVEDVNENQKGILFEKLVKVFNGDLKGKTVA
LWGLAFKPGTDDMREAPALVLIEKLKQSGCNVRAYDPAAMDESRRRIGESVYYAHDMYDAALDADALILVTEWKEFRLPT
WGVIKKAMKQPVVLDGRNIYDGDELQEMGFVYHCIGR

Sequences:

>Translated_437_residues
MNIAIVGTGYVGLVTGTCFAETGVDVTCVDVNADKIANLQQGIIPIYEPGLEDMVLRNVKAGRLHFTTSLESCLDNVDIV
FSAVGTPPDEDGSADLRYVLEVAKTIGANMKKYTLVVTKSTVPVGTARKVKAAIREELEKRGESIDFDVASNPEFLKEGN
AIDDFMSPDRVVVGVESERAKKLMTKLYKPFMLVNFRVIFMDIPSAEMTKYAANSMLATRISFMNDIANLCELVGADVNM
VRDGIGSDSRIGRKFLYPGCGYGGSCFPKDVKALIKTAEQNGYSMQVLKAVEDVNENQKGILFEKLVKVFNGDLKGKTVA
LWGLAFKPGTDDMREAPALVLIEKLKQSGCNVRAYDPAAMDESRRRIGESVYYAHDMYDAALDADALILVTEWKEFRLPT
WGVIKKAMKQPVVLDGRNIYDGDELQEMGFVYHCIGR
>Mature_437_residues
MNIAIVGTGYVGLVTGTCFAETGVDVTCVDVNADKIANLQQGIIPIYEPGLEDMVLRNVKAGRLHFTTSLESCLDNVDIV
FSAVGTPPDEDGSADLRYVLEVAKTIGANMKKYTLVVTKSTVPVGTARKVKAAIREELEKRGESIDFDVASNPEFLKEGN
AIDDFMSPDRVVVGVESERAKKLMTKLYKPFMLVNFRVIFMDIPSAEMTKYAANSMLATRISFMNDIANLCELVGADVNM
VRDGIGSDSRIGRKFLYPGCGYGGSCFPKDVKALIKTAEQNGYSMQVLKAVEDVNENQKGILFEKLVKVFNGDLKGKTVA
LWGLAFKPGTDDMREAPALVLIEKLKQSGCNVRAYDPAAMDESRRRIGESVYYAHDMYDAALDADALILVTEWKEFRLPT
WGVIKKAMKQPVVLDGRNIYDGDELQEMGFVYHCIGR

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=463, Percent_Identity=34.341252699784, Blast_Score=244, Evalue=2e-64,
Organism=Homo sapiens, GI296040438, Length=370, Percent_Identity=34.5945945945946, Blast_Score=196, Evalue=4e-50,
Organism=Homo sapiens, GI296040443, Length=319, Percent_Identity=34.7962382445141, Blast_Score=174, Evalue=2e-43,
Organism=Escherichia coli, GI1788340, Length=365, Percent_Identity=29.8630136986301, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI48994968, Length=439, Percent_Identity=28.7015945330296, Blast_Score=144, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17560350, Length=458, Percent_Identity=34.9344978165939, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI17136908, Length=470, Percent_Identity=35.1063829787234, Blast_Score=258, Evalue=7e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 48148; Mature: 48148

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIAIVGTGYVGLVTGTCFAETGVDVTCVDVNADKIANLQQGIIPIYEPGLEDMVLRNVK
CEEEEEECCCEEHHCCHHHHCCCCEEEEEECCHHHHHHHHHCCCCCCCCCHHHHHHHCCC
AGRLHFTTSLESCLDNVDIVFSAVGTPPDEDGSADLRYVLEVAKTIGANMKKYTLVVTKS
CCEEEEEEHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEC
TVPVGTARKVKAAIREELEKRGESIDFDVASNPEFLKEGNAIDDFMSPDRVVVGVESERA
CCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHCCCCHHHHCCCCEEEEECCHHHH
KKLMTKLYKPFMLVNFRVIFMDIPSAEMTKYAANSMLATRISFMNDIANLCELVGADVNM
HHHHHHHHCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRDGIGSDSRIGRKFLYPGCGYGGSCFPKDVKALIKTAEQNGYSMQVLKAVEDVNENQKG
HHHCCCCCHHCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
ILFEKLVKVFNGDLKGKTVALWGLAFKPGTDDMREAPALVLIEKLKQSGCNVRAYDPAAM
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHHCCCCEEECCCHHH
DESRRRIGESVYYAHDMYDAALDADALILVTEWKEFRLPTWGVIKKAMKQPVVLDGRNIY
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHCCCHHHHHHHHHCCCEEECCCCCC
DGDELQEMGFVYHCIGR
CCHHHHHHCHHHHCCCC
>Mature Secondary Structure
MNIAIVGTGYVGLVTGTCFAETGVDVTCVDVNADKIANLQQGIIPIYEPGLEDMVLRNVK
CEEEEEECCCEEHHCCHHHHCCCCEEEEEECCHHHHHHHHHCCCCCCCCCHHHHHHHCCC
AGRLHFTTSLESCLDNVDIVFSAVGTPPDEDGSADLRYVLEVAKTIGANMKKYTLVVTKS
CCEEEEEEHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEC
TVPVGTARKVKAAIREELEKRGESIDFDVASNPEFLKEGNAIDDFMSPDRVVVGVESERA
CCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHCCCCHHHHCCCCEEEEECCHHHH
KKLMTKLYKPFMLVNFRVIFMDIPSAEMTKYAANSMLATRISFMNDIANLCELVGADVNM
HHHHHHHHCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRDGIGSDSRIGRKFLYPGCGYGGSCFPKDVKALIKTAEQNGYSMQVLKAVEDVNENQKG
HHHCCCCCHHCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCC
ILFEKLVKVFNGDLKGKTVALWGLAFKPGTDDMREAPALVLIEKLKQSGCNVRAYDPAAM
HHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHHCCCCEEECCCHHH
DESRRRIGESVYYAHDMYDAALDADALILVTEWKEFRLPTWGVIKKAMKQPVVLDGRNIY
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECHHHHCCCHHHHHHHHHCCCEEECCCCCC
DGDELQEMGFVYHCIGR
CCHHHHHHCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]