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The map label for this gene is phnW

Identifier: 150005522

GI number: 150005522

Start: 3804607

End: 3805695

Strand: Reverse

Name: phnW

Synonym: BVU_3006

Alternate gene names: 150005522

Gene position: 3805695-3804607 (Counterclockwise)

Preceding gene: 150005523

Following gene: 150005518

Centisome position: 73.71

GC content: 45.45

Gene sequence:

>1089_bases
ATGAGACCATACTTACTTTTAACCCCCGGCCCTTTAACCACTTCTGAAAGCGTAAAAACAGCCATGATGACCGACTGGTG
CACATGGGATGAAGACTACAATGTTCACATCGTAGAGGAAATACGTAAAGGATTGGTACAACTGGCTACACGAAAAACAG
ATGAGTACACCAGCATCCTGATGCAGGGAAGCGGTACTTATTGCGTAGAGGCGACCTTGGGAAGTGTGATTACGCCCAAA
CACAAATTATTGATTCTGAGCAACGGTGCATACGGAGACCGCATGGGAAACATTGCAGAATATCATGAAATGAACTATGA
TATGCTGGCCTTTGATGAAACAGAACAAGTATCTGTGGAGTATGTGGATGATTATCTGGCACACAATGCAGAAATCACGC
ATGTGGCAGTGGTACATTGCGAAACTACAACCGGTATCCTGAACCCGTTAAAGGAAATAGCCCACATGGTAAAGATGCAT
GGTAAAAAGCTGATAGTGGATGCAATGAGCAGCTTTGGCGGCGTGCCGTTGGATGTAGAGGAATTAGGCATCGACTTTAT
GATCAGCAGTGCCAACAAATGTATTCAGGGAGTTCCCGGCTTTGGTTTCATCATTGCACGTAAATCCGAATTACAATATT
GTAAAGGAGTATCAAAGAGTCTTTCTCTGGACATCTACGACCAATGGGATGCGATGGAGAAAGGACATGGAAAATGGCGC
TTCACCTCGCCTACACATGTAGTGCGTGCCTTTAAACAAGCCATGGACGAACTGGCAGCCGAAGGCGGTGTGGAAGCCCG
GCATGCACGCTACTGCCGTAATCACGATGTACTGGTAGAAGGTATGCGGTCACTGGGATTCAAGACCTTACTGAAAGATG
AAGTCCAATCCCCTGTCATCACTTCCTTCCTTTATCCTGACAAGGAGTTCGATTTCAAGGAATTCTATCATCAGTTGAAG
GAAAAAGGATTCGTTATCTATCCGGGAAAGATTTCCCAGGCAGATACTTTCCGCATCGGAAACATCGGTGATGTGTTCCC
CGAAGATTTCAGCAGATTGATTGAAGCTATCAAGACCGTCGCAAAATAA

Upstream 100 bases:

>100_bases
AAAACGTATGTATATGGCAGGTGCGCATTATGTAGTAAACACCATTGCCGAACTTCCCGAAATTATTGAAATTATTAACC
ATAAAATGAATTAAACGATT

Downstream 100 bases:

>100_bases
AAAATAAATCTAGCTTTATGGCTCGGGCGCAGTGATTGCGCCCGAATTTGTTTCTACCCTTCTTCCGTTACAAGATCATT
TGGAACCGGAGCTGCACGAC

Product: 2-aminoethylphosphonate--pyruvate transaminase

Products: NA

Alternate protein names: 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MRPYLLLTPGPLTTSESVKTAMMTDWCTWDEDYNVHIVEEIRKGLVQLATRKTDEYTSILMQGSGTYCVEATLGSVITPK
HKLLILSNGAYGDRMGNIAEYHEMNYDMLAFDETEQVSVEYVDDYLAHNAEITHVAVVHCETTTGILNPLKEIAHMVKMH
GKKLIVDAMSSFGGVPLDVEELGIDFMISSANKCIQGVPGFGFIIARKSELQYCKGVSKSLSLDIYDQWDAMEKGHGKWR
FTSPTHVVRAFKQAMDELAAEGGVEARHARYCRNHDVLVEGMRSLGFKTLLKDEVQSPVITSFLYPDKEFDFKEFYHQLK
EKGFVIYPGKISQADTFRIGNIGDVFPEDFSRLIEAIKTVAK

Sequences:

>Translated_362_residues
MRPYLLLTPGPLTTSESVKTAMMTDWCTWDEDYNVHIVEEIRKGLVQLATRKTDEYTSILMQGSGTYCVEATLGSVITPK
HKLLILSNGAYGDRMGNIAEYHEMNYDMLAFDETEQVSVEYVDDYLAHNAEITHVAVVHCETTTGILNPLKEIAHMVKMH
GKKLIVDAMSSFGGVPLDVEELGIDFMISSANKCIQGVPGFGFIIARKSELQYCKGVSKSLSLDIYDQWDAMEKGHGKWR
FTSPTHVVRAFKQAMDELAAEGGVEARHARYCRNHDVLVEGMRSLGFKTLLKDEVQSPVITSFLYPDKEFDFKEFYHQLK
EKGFVIYPGKISQADTFRIGNIGDVFPEDFSRLIEAIKTVAK
>Mature_362_residues
MRPYLLLTPGPLTTSESVKTAMMTDWCTWDEDYNVHIVEEIRKGLVQLATRKTDEYTSILMQGSGTYCVEATLGSVITPK
HKLLILSNGAYGDRMGNIAEYHEMNYDMLAFDETEQVSVEYVDDYLAHNAEITHVAVVHCETTTGILNPLKEIAHMVKMH
GKKLIVDAMSSFGGVPLDVEELGIDFMISSANKCIQGVPGFGFIIARKSELQYCKGVSKSLSLDIYDQWDAMEKGHGKWR
FTSPTHVVRAFKQAMDELAAEGGVEARHARYCRNHDVLVEGMRSLGFKTLLKDEVQSPVITSFLYPDKEFDFKEFYHQLK
EKGFVIYPGKISQADTFRIGNIGDVFPEDFSRLIEAIKTVAK

Specific function: Involved in phosphonate degradation

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily

Homologues:

Organism=Homo sapiens, GI4557289, Length=365, Percent_Identity=23.5616438356164, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17536281, Length=351, Percent_Identity=23.3618233618234, Blast_Score=100, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6321079, Length=272, Percent_Identity=23.5294117647059, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHNW_BACV8 (A6L4N0)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001300266.1
- ProteinModelPortal:   A6L4N0
- SMR:   A6L4N0
- STRING:   A6L4N0
- GeneID:   5303967
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_3006
- NMPDR:   fig|435590.6.peg.2815
- eggNOG:   COG0075
- HOGENOM:   HBG423997
- OMA:   HSLAMDL
- ProtClustDB:   PRK13479
- HAMAP:   MF_01376
- InterPro:   IPR017688
- InterPro:   IPR000192
- InterPro:   IPR012703
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- TIGRFAMs:   TIGR03301
- TIGRFAMs:   TIGR02326

Pfam domain/function: PF00266 Aminotran_5; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.37

Molecular weight: Translated: 40764; Mature: 40764

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPYLLLTPGPLTTSESVKTAMMTDWCTWDEDYNVHIVEEIRKGLVQLATRKTDEYTSIL
CCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHE
MQGSGTYCVEATLGSVITPKHKLLILSNGAYGDRMGNIAEYHEMNYDMLAFDETEQVSVE
EECCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHCCCCEEEECCCHHHHHH
YVDDYLAHNAEITHVAVVHCETTTGILNPLKEIAHMVKMHGKKLIVDAMSSFGGVPLDVE
HHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHH
ELGIDFMISSANKCIQGVPGFGFIIARKSELQYCKGVSKSLSLDIYDQWDAMEKGHGKWR
HHCHHEEEHHHHHHHHCCCCCEEEEEECHHHHHHHCCCHHCEEEEEHHHHHHHCCCCCEE
FTSPTHVVRAFKQAMDELAAEGGVEARHARYCRNHDVLVEGMRSLGFKTLLKDEVQSPVI
ECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHCCCHH
TSFLYPDKEFDFKEFYHQLKEKGFVIYPGKISQADTFRIGNIGDVFPEDFSRLIEAIKTV
HHHCCCCCCCCHHHHHHHHHHCCEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHH
AK
CC
>Mature Secondary Structure
MRPYLLLTPGPLTTSESVKTAMMTDWCTWDEDYNVHIVEEIRKGLVQLATRKTDEYTSIL
CCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHCCCHHHHHHE
MQGSGTYCVEATLGSVITPKHKLLILSNGAYGDRMGNIAEYHEMNYDMLAFDETEQVSVE
EECCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHCCCCEEEECCCHHHHHH
YVDDYLAHNAEITHVAVVHCETTTGILNPLKEIAHMVKMHGKKLIVDAMSSFGGVPLDVE
HHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHH
ELGIDFMISSANKCIQGVPGFGFIIARKSELQYCKGVSKSLSLDIYDQWDAMEKGHGKWR
HHCHHEEEHHHHHHHHCCCCCEEEEEECHHHHHHHCCCHHCEEEEEHHHHHHHCCCCCEE
FTSPTHVVRAFKQAMDELAAEGGVEARHARYCRNHDVLVEGMRSLGFKTLLKDEVQSPVI
ECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHCCCHH
TSFLYPDKEFDFKEFYHQLKEKGFVIYPGKISQADTFRIGNIGDVFPEDFSRLIEAIKTV
HHHCCCCCCCCHHHHHHHHHHCCEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHH
AK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA