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The map label for this gene is wzc [H]

Identifier: 150005204

GI number: 150005204

Start: 3394299

End: 3396710

Strand: Reverse

Name: wzc [H]

Synonym: BVU_2674

Alternate gene names: 150005204

Gene position: 3396710-3394299 (Counterclockwise)

Preceding gene: 150005205

Following gene: 150005199

Centisome position: 65.79

GC content: 50.25

Gene sequence:

>2412_bases
ATGAAAGAAGACTTATACGACGACCTCTATCTGGAAGAAAAAGAAGAAAAGACCGATTTCAAAGCGATTCTTTTCAAATA
CGCCATCCACTGGCCCTGGTTTCTGGCATGTACCCTGCTGTGCATGGCGGGAGCCTGGCTCTATTTGTGTTACACTCCAT
CGGTGTACAACATCTCGGCATCCGTCATCATCAAGGACAATGACAAGAACAGCAAAGCAAGCAGCGGCATGGGCGACCTA
GAAGACCTGGGCTTCTATTCCTCCATCAACAACTTTGACAATGAAGTGGAAATCCTGCAATCGCGCACGCTTATCAAAAA
AGTGGTGGAAGAACTGGATCTTTACATCAGCTATGCCACGAAGAGCAGTTTCCATGACATCGAACTTTACAAAAGTTCCC
CTGTGAAAGTATGGATTACCCCCGAAGAAGCCCAGAAACTGCCCGCCCCCGCGCGTCTTCACCTGACCTTGCAGCCGGGC
AACAAGCTGAATGTGAAACTCCGGATAGGAGAAGAGGAATACAACAAGCAGTTCGACAAGCTGCCCGCCTTGCTGACCAC
CCCGTCGGGCACGTTCAGCTTTACCCCCAAAGACTCTACAACCGTCCAAAGCACGCAGGAAATCATGGCTACGGTTTCTT
CCCCCCGCAGTGTGGCAAACGCTTACCGGGGAGCATTGAGCATAGAGCCTACTTCCAAATCCACCACTATCGCACAGATC
TCTGTCAAGAGCACGCATACGCAGCGCGGCATGGATTTCATCAACAAGCTGGTGGAAGTCTACAACCGGGATGCCAACGA
TGACAAAAACGAAGTGGCTACCAAGACCGCGGAATTTATTGATGAACGTATCAAAATCATCAACGGCGAATTGGGAACCA
CGGAACAGGAACTGGAAACCTTCAAGCGCGATGCCGGGCTCACCGACTTGAAAAGCGACGCCCAACTGGCATTGAGTGAA
AACTCGGAATACGAAAAGAAACGTGCTGAAAACAGCACCCAGCTCCGGCTGGTACAATTCCTGGCCGGCTATGCCAACAA
TCCGGATCATGCCTACGAAGTACTTCCGGTCAATGTGGGCCTGACAGATACCGGTCTTGCCGAGCTGATCAACCGCTACA
ACGAGATGCTGCTGGAACGCAAGCGCCTGCTCCGTTCCTCTCAGGAAAACAACCCGGTGGTAGTCAATCTGGATGCCAGC
ATCCGCGCCATGCGCAGCAATGTGCTGACCACCATCAACAGCGTACAAAGAGGTTTGGCCATCACCCAGGCGGATCTGGA
ACGTCAGGCAGGCAAATATGCCGGACGCATCACCAATGCTCCGGGACAGGAACGCCAGCTGGTCAGCATCTCGCGCCAGC
AGGAAATCAAAGCCGGCCTTTACCTGATGCTGCTGCAAAAGCGTGAAGAAAACGCCATCACTCTGGCATCTACCGCCAAC
AACGCCCGCATGGTGGACGAAGCACTGGCAGATGCCATCCCCGTATCTCCCAAAGGGAAGATGATTTATCTGGTAGCACT
GATTCTGGGAATCGCCCTGCCGGTAGTTGTCATCTATATCATCGAACTCTTAAAATACAAGATAGAGGGCCGCGCCGATG
TGGAAAAAATCACCTCCCTTCCCATTGTGGGCGATGTACCCCTGTCGGAAGATAAAGGAAAAGAAGAAAGCATTGTAGTA
CACGAAAACCAAAACGACCTGATGGCCGAAACCTTCCGTAATGTACGCACCAATGTACTTTATATGATGAGGAGCGACGA
GAAAGTCATATTGGTTACCTCCACCACCACAGGAGAAGGCAAAACCTTTATCGCTTCCAATCTGGCTGTCAGTCTGGCTT
TATTAGGAAAGAAAATCGTGATCGTGGGGCTTGACATCCGCAAGCCGAGTCTGAACAAAGCTTTCAACTTATCACACAGG
GAACAAGGCATCAGCCAGTTCCTCGCCAATCCGGAACATACCGACCTGATGTCGCTGGTACAAGTTTCACGCATCAATGC
CAACTTGTCCATTCTGCCCGGAGGGCCTATTCCTCCCAACCCGACCGAACTGGTGGCACGTGAATCTTTGTCTCAGGCTA
TCGACATACTGAAAAAGCATTTTGACTATATCATTCTGGATACCGCCCCCATCGGCATGGTGACCGATACCCTGCTGATT
TCGCGCGTAGCCAACGCCAGCATCTATGTGTGCCGGGCAGACTACACCCACAAGGCAGATTATACTTTAATCAACGAACT
GAGCGAACAGAAAAAACTGCCCAACCTATGTACCCTTATCAACGGACTGGACATGAAGAAAAAGAAGTACGGATATTACT
ATGGATACGGCAAGTATGGCAAGTATTACGGATACGGTAAAAAATACGGTTACGGCTATGGATATGGCACTGAAAATGTA
AATAAAAAGTAA

Upstream 100 bases:

>100_bases
ATGCAAGTATCAGCAACAGCACCACCATCTGGTTCTCGGTAGTAGGAACTCTGGTTGCACTGGCCAGCCTGATCGTAACC
ATAACCAAATAAACAGAACT

Downstream 100 bases:

>100_bases
TTTCAAAAGTAATTACATAATAACATAAGACTAATTCTCTTTCCAATGTGTTAATATTTTAACAAATTCAGAAGAGAATT
AGTCTTATTACGTTTCAATA

Product: putative EPS related membrane protein

Products: ADP; protein tyrosine phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 803; Mature: 803

Protein sequence:

>803_residues
MKEDLYDDLYLEEKEEKTDFKAILFKYAIHWPWFLACTLLCMAGAWLYLCYTPSVYNISASVIIKDNDKNSKASSGMGDL
EDLGFYSSINNFDNEVEILQSRTLIKKVVEELDLYISYATKSSFHDIELYKSSPVKVWITPEEAQKLPAPARLHLTLQPG
NKLNVKLRIGEEEYNKQFDKLPALLTTPSGTFSFTPKDSTTVQSTQEIMATVSSPRSVANAYRGALSIEPTSKSTTIAQI
SVKSTHTQRGMDFINKLVEVYNRDANDDKNEVATKTAEFIDERIKIINGELGTTEQELETFKRDAGLTDLKSDAQLALSE
NSEYEKKRAENSTQLRLVQFLAGYANNPDHAYEVLPVNVGLTDTGLAELINRYNEMLLERKRLLRSSQENNPVVVNLDAS
IRAMRSNVLTTINSVQRGLAITQADLERQAGKYAGRITNAPGQERQLVSISRQQEIKAGLYLMLLQKREENAITLASTAN
NARMVDEALADAIPVSPKGKMIYLVALILGIALPVVVIYIIELLKYKIEGRADVEKITSLPIVGDVPLSEDKGKEESIVV
HENQNDLMAETFRNVRTNVLYMMRSDEKVILVTSTTTGEGKTFIASNLAVSLALLGKKIVIVGLDIRKPSLNKAFNLSHR
EQGISQFLANPEHTDLMSLVQVSRINANLSILPGGPIPPNPTELVARESLSQAIDILKKHFDYIILDTAPIGMVTDTLLI
SRVANASIYVCRADYTHKADYTLINELSEQKKLPNLCTLINGLDMKKKKYGYYYGYGKYGKYYGYGKKYGYGYGYGTENV
NKK

Sequences:

>Translated_803_residues
MKEDLYDDLYLEEKEEKTDFKAILFKYAIHWPWFLACTLLCMAGAWLYLCYTPSVYNISASVIIKDNDKNSKASSGMGDL
EDLGFYSSINNFDNEVEILQSRTLIKKVVEELDLYISYATKSSFHDIELYKSSPVKVWITPEEAQKLPAPARLHLTLQPG
NKLNVKLRIGEEEYNKQFDKLPALLTTPSGTFSFTPKDSTTVQSTQEIMATVSSPRSVANAYRGALSIEPTSKSTTIAQI
SVKSTHTQRGMDFINKLVEVYNRDANDDKNEVATKTAEFIDERIKIINGELGTTEQELETFKRDAGLTDLKSDAQLALSE
NSEYEKKRAENSTQLRLVQFLAGYANNPDHAYEVLPVNVGLTDTGLAELINRYNEMLLERKRLLRSSQENNPVVVNLDAS
IRAMRSNVLTTINSVQRGLAITQADLERQAGKYAGRITNAPGQERQLVSISRQQEIKAGLYLMLLQKREENAITLASTAN
NARMVDEALADAIPVSPKGKMIYLVALILGIALPVVVIYIIELLKYKIEGRADVEKITSLPIVGDVPLSEDKGKEESIVV
HENQNDLMAETFRNVRTNVLYMMRSDEKVILVTSTTTGEGKTFIASNLAVSLALLGKKIVIVGLDIRKPSLNKAFNLSHR
EQGISQFLANPEHTDLMSLVQVSRINANLSILPGGPIPPNPTELVARESLSQAIDILKKHFDYIILDTAPIGMVTDTLLI
SRVANASIYVCRADYTHKADYTLINELSEQKKLPNLCTLINGLDMKKKKYGYYYGYGKYGKYYGYGKKYGYGYGYGTENV
NKK
>Mature_803_residues
MKEDLYDDLYLEEKEEKTDFKAILFKYAIHWPWFLACTLLCMAGAWLYLCYTPSVYNISASVIIKDNDKNSKASSGMGDL
EDLGFYSSINNFDNEVEILQSRTLIKKVVEELDLYISYATKSSFHDIELYKSSPVKVWITPEEAQKLPAPARLHLTLQPG
NKLNVKLRIGEEEYNKQFDKLPALLTTPSGTFSFTPKDSTTVQSTQEIMATVSSPRSVANAYRGALSIEPTSKSTTIAQI
SVKSTHTQRGMDFINKLVEVYNRDANDDKNEVATKTAEFIDERIKIINGELGTTEQELETFKRDAGLTDLKSDAQLALSE
NSEYEKKRAENSTQLRLVQFLAGYANNPDHAYEVLPVNVGLTDTGLAELINRYNEMLLERKRLLRSSQENNPVVVNLDAS
IRAMRSNVLTTINSVQRGLAITQADLERQAGKYAGRITNAPGQERQLVSISRQQEIKAGLYLMLLQKREENAITLASTAN
NARMVDEALADAIPVSPKGKMIYLVALILGIALPVVVIYIIELLKYKIEGRADVEKITSLPIVGDVPLSEDKGKEESIVV
HENQNDLMAETFRNVRTNVLYMMRSDEKVILVTSTTTGEGKTFIASNLAVSLALLGKKIVIVGLDIRKPSLNKAFNLSHR
EQGISQFLANPEHTDLMSLVQVSRINANLSILPGGPIPPNPTELVARESLSQAIDILKKHFDYIILDTAPIGMVTDTLLI
SRVANASIYVCRADYTHKADYTLINELSEQKKLPNLCTLINGLDMKKKKYGYYYGYGKYGKYYGYGKKYGYGYGYGTENV
NKK

Specific function: Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium. Phosphorylates udg [H]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the etk/wzc family [H]

Homologues:

Organism=Escherichia coli, GI87082032, Length=427, Percent_Identity=27.6346604215457, Blast_Score=155, Evalue=7e-39,
Organism=Escherichia coli, GI1787216, Length=367, Percent_Identity=24.7956403269755, Blast_Score=141, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR005702
- InterPro:   IPR003856 [H]

Pfam domain/function: PF01656 CbiA; PF02706 Wzz [H]

EC number: 2.7.1.112 [C]

Molecular weight: Translated: 89813; Mature: 89813

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEDLYDDLYLEEKEEKTDFKAILFKYAIHWPWFLACTLLCMAGAWLYLCYTPSVYNISA
CCCCHHCHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEEECCCEEEEEE
SVIIKDNDKNSKASSGMGDLEDLGFYSSINNFDNEVEILQSRTLIKKVVEELDLYISYAT
EEEEEECCCCCCCCCCCCCHHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEEECC
KSSFHDIELYKSSPVKVWITPEEAQKLPAPARLHLTLQPGNKLNVKLRIGEEEYNKQFDK
CCCCCEEEEECCCCEEEEEEHHHHHHCCCCEEEEEEECCCCEEEEEEEECCHHHHHHHHH
LPALLTTPSGTFSFTPKDSTTVQSTQEIMATVSSPRSVANAYRGALSIEPTSKSTTIAQI
CCCEEECCCCCEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCEEECCCCCCCEEEEE
SVKSTHTQRGMDFINKLVEVYNRDANDDKNEVATKTAEFIDERIKIINGELGTTEQELET
EECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
FKRDAGLTDLKSDAQLALSENSEYEKKRAENSTQLRLVQFLAGYANNPDHAYEVLPVNVG
HHHCCCCCCCCCCCEEEECCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECC
LTDTGLAELINRYNEMLLERKRLLRSSQENNPVVVNLDASIRAMRSNVLTTINSVQRGLA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCHH
ITQADLERQAGKYAGRITNAPGQERQLVSISRQQEIKAGLYLMLLQKREENAITLASTAN
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEHHHHCCCCCEEEEECCC
NARMVDEALADAIPVSPKGKMIYLVALILGIALPVVVIYIIELLKYKIEGRADVEKITSL
CHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCC
PIVGDVPLSEDKGKEESIVVHENQNDLMAETFRNVRTNVLYMMRSDEKVILVTSTTTGEG
CEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHEEEEEEECCCEEEEEEECCCCCC
KTFIASNLAVSLALLGKKIVIVGLDIRKPSLNKAFNLSHREQGISQFLANPEHTDLMSLV
CEEEHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
QVSRINANLSILPGGPIPPNPTELVARESLSQAIDILKKHFDYIILDTAPIGMVTDTLLI
HHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHH
SRVANASIYVCRADYTHKADYTLINELSEQKKLPNLCTLINGLDMKKKKYGYYYGYGKYG
HHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCHHHCCEEEEECCCC
KYYGYGKKYGYGYGYGTENVNKK
CCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKEDLYDDLYLEEKEEKTDFKAILFKYAIHWPWFLACTLLCMAGAWLYLCYTPSVYNISA
CCCCHHCHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEEECCCEEEEEE
SVIIKDNDKNSKASSGMGDLEDLGFYSSINNFDNEVEILQSRTLIKKVVEELDLYISYAT
EEEEEECCCCCCCCCCCCCHHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHEEEECC
KSSFHDIELYKSSPVKVWITPEEAQKLPAPARLHLTLQPGNKLNVKLRIGEEEYNKQFDK
CCCCCEEEEECCCCEEEEEEHHHHHHCCCCEEEEEEECCCCEEEEEEEECCHHHHHHHHH
LPALLTTPSGTFSFTPKDSTTVQSTQEIMATVSSPRSVANAYRGALSIEPTSKSTTIAQI
CCCEEECCCCCEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCEEECCCCCCCEEEEE
SVKSTHTQRGMDFINKLVEVYNRDANDDKNEVATKTAEFIDERIKIINGELGTTEQELET
EECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
FKRDAGLTDLKSDAQLALSENSEYEKKRAENSTQLRLVQFLAGYANNPDHAYEVLPVNVG
HHHCCCCCCCCCCCEEEECCCCHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECC
LTDTGLAELINRYNEMLLERKRLLRSSQENNPVVVNLDASIRAMRSNVLTTINSVQRGLA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHCHH
ITQADLERQAGKYAGRITNAPGQERQLVSISRQQEIKAGLYLMLLQKREENAITLASTAN
HHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEHHHHCCCCCEEEEECCC
NARMVDEALADAIPVSPKGKMIYLVALILGIALPVVVIYIIELLKYKIEGRADVEKITSL
CHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCC
PIVGDVPLSEDKGKEESIVVHENQNDLMAETFRNVRTNVLYMMRSDEKVILVTSTTTGEG
CEEECCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHEEEEEEECCCEEEEEEECCCCCC
KTFIASNLAVSLALLGKKIVIVGLDIRKPSLNKAFNLSHREQGISQFLANPEHTDLMSLV
CEEEHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
QVSRINANLSILPGGPIPPNPTELVARESLSQAIDILKKHFDYIILDTAPIGMVTDTLLI
HHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHH
SRVANASIYVCRADYTHKADYTLINELSEQKKLPNLCTLINGLDMKKKKYGYYYGYGKYG
HHHCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCHHHCCEEEEECCCC
KYYGYGKKYGYGYGYGTENVNKK
CCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; a protein tyrosine [C]

Specific reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]