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The map label for this gene is glnA [H]

Identifier: 148828049

GI number: 148828049

Start: 1447725

End: 1449137

Strand: Direct

Name: glnA [H]

Synonym: CGSHiGG_07850

Alternate gene names: 148828049

Gene position: 1447725-1449137 (Clockwise)

Preceding gene: 148828046

Following gene: 148828050

Centisome position: 76.71

GC content: 38.57

Gene sequence:

>1413_bases
ATGTCAAATGCCATTGCTTCCGTGTTTAAATTGATCGAAGAGAATGATATTAGGTTTGTATTGCTTCGTTTTACTGACAT
TAAAGGTAAAGAACATGGTGTTTCTATCCCAGTTAGCCTTGTTGATGAAGATATGTTTGAAGACGGCAAGATGTTTGATG
GCTCCTCTGTTGAAGGTTGGAAAACCATTAATAAAGCCGATATGTTGCTTATGCCAATAGCTGAAACGGCGGTTGTCGAT
CCATTCGCACAAATTCCGACACTTTCTATTCGTTGTAGTGTTTATGAACCAACGACAATGCAAAGCTATGATCGCGATCC
GCGCTCTATTGCAATTCGTGCAGAAAATTATATGCGTTCAACAGGTATTGCGGATCAAGCTTTTTTCGGCCCAGAGCCTG
AATTCTTCTTATTTGATGATGTGCGTTTTAATGTATCAATGAACAAAGCGTCTTTTTCTATTGATGATATAGAAGCTGCT
TGGAACACGAATAAAAAATATGAAGAAGGTAATAATGCTTATCGCCCATTGAAAAAAGGCGGATATTGTGCCGTTGCACC
GATTGATAGTGCGCACGATATTCGTTCTGAAATGTGCTTGATTTTAGAAGAAATGGGCCTTGTGATTGAAGCCCATCATC
ATGAAGTGGCGACTGCGGGACAAAACGAAATTGCGACTAAATTTAATACGCTAACTTTAAAAGCGGATGAAACCCAAATT
TATAAATATGTCGTACAAAACGTTGCATTAGAGCACGGTAAAACGGCGTGTTTTATGCCCAAACCAATTACTGGAGATAA
TGGTTCGGGTATGCACTGTAATATGTCGTTAAGTAAAGACGGGAAAAATATTTTCCAAGGCGATAAATATGCAGGTCTTT
CTGAAACCGCACTTTACTACATCGGCGGTATCATTAAGCACGCTAAAGCCTTAAATGCGTTCACTAATCCAAGTACTAAT
TCATATAAACGTTTAGTGCCTGGTTATGAAGCACCAGTATTGTTGGCTTACTCTGCAAGCAATCGTTCTGCTTCAATTCG
TATTCCTGCTGTAACCAATCCAAAAGCGATTCGCGTAGAATCACGTTTCCCAGATCCATTGGCAAACCCATATTTAGCAT
TTGCTGCATTATTAATGGCAGGTCTTGATGGCGTGGTAAATAAAATCCATCCAGGAGATGCGATGGATAAAAATCTTTAC
GATCTTCCACCAGAAGAATTAAAAGATATTCCAGCGGTTGCAAGCTCTTTAGAAGAAGCATTGAATTCATTAGAGAAAGA
CTATGAATTTTTAACTCAAGGTGGCGTATTTGCTAAAGATTTTATTGATGCGTTTATCAGTATCAAACGTAAAGAAGTGG
AACGTTTAAATATGGCACCACATCCAGTTGAATTTGAAATGTATTATGCGTAA

Upstream 100 bases:

>100_bases
TCTGTGCTTTTTACTATAACGCCACAACAAATCTAATGAAAGTCAGATTTGATTAGACTATAATACTTCCTTAATTTTTT
ATATAGAAAGAGGATCTACT

Downstream 100 bases:

>100_bases
TGATATATAAACAAGAACAATGCGGTGAAATTTCGCCGTATTTTTTTAAAGGAGTAAATATGACTAAGATTTCTTCTCAA
AAGAATGACTAGATTGATTT

Product: glutamine synthetase

Products: NA

Alternate protein names: Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MSNAIASVFKLIEENDIRFVLLRFTDIKGKEHGVSIPVSLVDEDMFEDGKMFDGSSVEGWKTINKADMLLMPIAETAVVD
PFAQIPTLSIRCSVYEPTTMQSYDRDPRSIAIRAENYMRSTGIADQAFFGPEPEFFLFDDVRFNVSMNKASFSIDDIEAA
WNTNKKYEEGNNAYRPLKKGGYCAVAPIDSAHDIRSEMCLILEEMGLVIEAHHHEVATAGQNEIATKFNTLTLKADETQI
YKYVVQNVALEHGKTACFMPKPITGDNGSGMHCNMSLSKDGKNIFQGDKYAGLSETALYYIGGIIKHAKALNAFTNPSTN
SYKRLVPGYEAPVLLAYSASNRSASIRIPAVTNPKAIRVESRFPDPLANPYLAFAALLMAGLDGVVNKIHPGDAMDKNLY
DLPPEELKDIPAVASSLEEALNSLEKDYEFLTQGGVFAKDFIDAFISIKRKEVERLNMAPHPVEFEMYYA

Sequences:

>Translated_470_residues
MSNAIASVFKLIEENDIRFVLLRFTDIKGKEHGVSIPVSLVDEDMFEDGKMFDGSSVEGWKTINKADMLLMPIAETAVVD
PFAQIPTLSIRCSVYEPTTMQSYDRDPRSIAIRAENYMRSTGIADQAFFGPEPEFFLFDDVRFNVSMNKASFSIDDIEAA
WNTNKKYEEGNNAYRPLKKGGYCAVAPIDSAHDIRSEMCLILEEMGLVIEAHHHEVATAGQNEIATKFNTLTLKADETQI
YKYVVQNVALEHGKTACFMPKPITGDNGSGMHCNMSLSKDGKNIFQGDKYAGLSETALYYIGGIIKHAKALNAFTNPSTN
SYKRLVPGYEAPVLLAYSASNRSASIRIPAVTNPKAIRVESRFPDPLANPYLAFAALLMAGLDGVVNKIHPGDAMDKNLY
DLPPEELKDIPAVASSLEEALNSLEKDYEFLTQGGVFAKDFIDAFISIKRKEVERLNMAPHPVEFEMYYA
>Mature_469_residues
SNAIASVFKLIEENDIRFVLLRFTDIKGKEHGVSIPVSLVDEDMFEDGKMFDGSSVEGWKTINKADMLLMPIAETAVVDP
FAQIPTLSIRCSVYEPTTMQSYDRDPRSIAIRAENYMRSTGIADQAFFGPEPEFFLFDDVRFNVSMNKASFSIDDIEAAW
NTNKKYEEGNNAYRPLKKGGYCAVAPIDSAHDIRSEMCLILEEMGLVIEAHHHEVATAGQNEIATKFNTLTLKADETQIY
KYVVQNVALEHGKTACFMPKPITGDNGSGMHCNMSLSKDGKNIFQGDKYAGLSETALYYIGGIIKHAKALNAFTNPSTNS
YKRLVPGYEAPVLLAYSASNRSASIRIPAVTNPKAIRVESRFPDPLANPYLAFAALLMAGLDGVVNKIHPGDAMDKNLYD
LPPEELKDIPAVASSLEEALNSLEKDYEFLTQGGVFAKDFIDAFISIKRKEVERLNMAPHPVEFEMYYA

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=501, Percent_Identity=23.3532934131737, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI1790301, Length=463, Percent_Identity=69.7624190064795, Blast_Score=699, Evalue=0.0,
Organism=Escherichia coli, GI87081870, Length=175, Percent_Identity=32.5714285714286, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809
- InterPro:   IPR001637 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 52175; Mature: 52044

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP ; PS00182 GLNA_ADENYLATION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNAIASVFKLIEENDIRFVLLRFTDIKGKEHGVSIPVSLVDEDMFEDGKMFDGSSVEGW
CCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCH
KTINKADMLLMPIAETAVVDPFAQIPTLSIRCSVYEPTTMQSYDRDPRSIAIRAENYMRS
HCCCCCCEEEEECHHHHHHCCHHHCCEEEEEEEEECCCCHHHCCCCCCEEEEEEHHHHHH
TGIADQAFFGPEPEFFLFDDVRFNVSMNKASFSIDDIEAAWNTNKKYEEGNNAYRPLKKG
CCCCCCCCCCCCCCEEEEEEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCC
GYCAVAPIDSAHDIRSEMCLILEEMGLVIEAHHHEVATAGQNEIATKFNTLTLKADETQI
CEEEEECCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHCCCCHHHEEEEEEEEECCHHHH
YKYVVQNVALEHGKTACFMPKPITGDNGSGMHCNMSLSKDGKNIFQGDKYAGLSETALYY
HHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEEECCCCCHHHCCCCCCCCCHHHHHH
IGGIIKHAKALNAFTNPSTNSYKRLVPGYEAPVLLAYSASNRSASIRIPAVTNPKAIRVE
HHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCEEEEEECCCCCEEEEECCCCCCCEEEEC
SRFPDPLANPYLAFAALLMAGLDGVVNKIHPGDAMDKNLYDLPPEELKDIPAVASSLEEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LNSLEKDYEFLTQGGVFAKDFIDAFISIKRKEVERLNMAPHPVEFEMYYA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC
>Mature Secondary Structure 
SNAIASVFKLIEENDIRFVLLRFTDIKGKEHGVSIPVSLVDEDMFEDGKMFDGSSVEGW
CHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCH
KTINKADMLLMPIAETAVVDPFAQIPTLSIRCSVYEPTTMQSYDRDPRSIAIRAENYMRS
HCCCCCCEEEEECHHHHHHCCHHHCCEEEEEEEEECCCCHHHCCCCCCEEEEEEHHHHHH
TGIADQAFFGPEPEFFLFDDVRFNVSMNKASFSIDDIEAAWNTNKKYEEGNNAYRPLKKG
CCCCCCCCCCCCCCEEEEEEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCC
GYCAVAPIDSAHDIRSEMCLILEEMGLVIEAHHHEVATAGQNEIATKFNTLTLKADETQI
CEEEEECCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHCCCCHHHEEEEEEEEECCHHHH
YKYVVQNVALEHGKTACFMPKPITGDNGSGMHCNMSLSKDGKNIFQGDKYAGLSETALYY
HHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEEECCCCCHHHCCCCCCCCCHHHHHH
IGGIIKHAKALNAFTNPSTNSYKRLVPGYEAPVLLAYSASNRSASIRIPAVTNPKAIRVE
HHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCEEEEEECCCCCEEEEECCCCCCCEEEEC
SRFPDPLANPYLAFAALLMAGLDGVVNKIHPGDAMDKNLYDLPPEELKDIPAVASSLEEA
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LNSLEKDYEFLTQGGVFAKDFIDAFISIKRKEVERLNMAPHPVEFEMYYA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]