Click here to switch to the map view.

The map label for this gene is galR [H]

Identifier: 148828008

GI number: 148828008

Start: 1402445

End: 1403446

Strand: Direct

Name: galR [H]

Synonym: CGSHiGG_07605

Alternate gene names: 148828008

Gene position: 1402445-1403446 (Clockwise)

Preceding gene: 148827994

Following gene: 148828009

Centisome position: 74.31

GC content: 38.52

Gene sequence:

>1002_bases
ATGAGTACTATTCGAGATGTCGCTAAATTAGCCAATGTTTCTGTCGCCACGGTCTCCCGAGTATTAAATCACTCGATTTC
CGTCAGTGAAAATACGCGTCTTGTGGTGGAACAAGCTATTGCGCAGTTATATTATCAACCTAATGCGAATGCTCAAGCCC
TTGCTGTGCAAAACACGGATACAATTGGAGTGGTAGTGACCGATGTGACTGATGCCTTTTTTGCGATTTTAGTGAAAGCG
GTGGACAAAGTAGCAGAAGCGCATCAAAAAACGATTTTAATCGGCATTGGTTATCATCATGCGGAAAAAGAGCGGGAAGC
AATTAATACCTTATTGCGTAAACGTTGTAGTTCTCTTGTTGTACATTCTAAAGCCTTATCTGATGATGAATTAAGCCATT
ATTTAAATACCGTGCCGGGAATGGTGATCATTAACCGTGTTATTAAAGGTTATGAACATCGTTGTGTCAGTTTAGATAAT
CAAAAAGGCACCTATTTAGCCACTGAAATGCTTATTCGTTATGGGCATCAACATATTGCATATATCGGTTCAAATCACGC
CATTTTTGACGAAGTTGAAAGACGAAATGGTTATCTTGCCGCATTAAAAGATCACAATTACCCCATCATTGAACAGGCGA
TAACTCTCAATACGCCAGATTTTGAAGGCGGTGAAAAGGCAATGATTGATTTACTCAGTTATAACAAAAATCTTACTGCA
GTCGTTGCCTATAATGATTCAATGGCAGCAGGTGCAATTTCTGTGCTTAATGAAAACAGTATCAGTGTACCAAGCCAATT
TTCAATTGTTGGTTTTGATGATATGCCGATTGCCCGTTATTTGATCCCAAAACTAACCACAATTCGCTATCCTATTGATT
TAATGGCAACTTATGCCGCTAAATTAGCATTAAGTTTAACCGATGAGAAAATAATTACCCCACCAATGGTTCAATTTAAC
CCTACTTTGGTACGCCGTTTTTCAGTGGAATCTAAAATATAA

Upstream 100 bases:

>100_bases
ATGATTTAGTTCATAATTATACAAGTAACCGCTTTCAATTTGGCTCAAATTATTTATGATCAAAGTATAAGATTTATAGA
TTATAACAAGGGAAAACGTT

Downstream 100 bases:

>100_bases
TATTAGCGATAAAATGTGATCTAGATCACAAATATTAATTTTTAATGTAATCGTTTTCATTTCTGTGAGTTCGATCACAG
ATTCTGAAAGAAAATTCAGT

Product: galactose operon repressor

Products: NA

Alternate protein names: Galactose operon repressor [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSTIRDVAKLANVSVATVSRVLNHSISVSENTRLVVEQAIAQLYYQPNANAQALAVQNTDTIGVVVTDVTDAFFAILVKA
VDKVAEAHQKTILIGIGYHHAEKEREAINTLLRKRCSSLVVHSKALSDDELSHYLNTVPGMVIINRVIKGYEHRCVSLDN
QKGTYLATEMLIRYGHQHIAYIGSNHAIFDEVERRNGYLAALKDHNYPIIEQAITLNTPDFEGGEKAMIDLLSYNKNLTA
VVAYNDSMAAGAISVLNENSISVPSQFSIVGFDDMPIARYLIPKLTTIRYPIDLMATYAAKLALSLTDEKIITPPMVQFN
PTLVRRFSVESKI

Sequences:

>Translated_333_residues
MSTIRDVAKLANVSVATVSRVLNHSISVSENTRLVVEQAIAQLYYQPNANAQALAVQNTDTIGVVVTDVTDAFFAILVKA
VDKVAEAHQKTILIGIGYHHAEKEREAINTLLRKRCSSLVVHSKALSDDELSHYLNTVPGMVIINRVIKGYEHRCVSLDN
QKGTYLATEMLIRYGHQHIAYIGSNHAIFDEVERRNGYLAALKDHNYPIIEQAITLNTPDFEGGEKAMIDLLSYNKNLTA
VVAYNDSMAAGAISVLNENSISVPSQFSIVGFDDMPIARYLIPKLTTIRYPIDLMATYAAKLALSLTDEKIITPPMVQFN
PTLVRRFSVESKI
>Mature_332_residues
STIRDVAKLANVSVATVSRVLNHSISVSENTRLVVEQAIAQLYYQPNANAQALAVQNTDTIGVVVTDVTDAFFAILVKAV
DKVAEAHQKTILIGIGYHHAEKEREAINTLLRKRCSSLVVHSKALSDDELSHYLNTVPGMVIINRVIKGYEHRCVSLDNQ
KGTYLATEMLIRYGHQHIAYIGSNHAIFDEVERRNGYLAALKDHNYPIIEQAITLNTPDFEGGEKAMIDLLSYNKNLTAV
VAYNDSMAAGAISVLNENSISVPSQFSIVGFDDMPIARYLIPKLTTIRYPIDLMATYAAKLALSLTDEKIITPPMVQFNP
TLVRRFSVESKI

Specific function: Repressor of the galactose operon. Binds galactose as an inducer [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788474, Length=332, Percent_Identity=57.5301204819277, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI1789202, Length=331, Percent_Identity=51.6616314199396, Blast_Score=341, Evalue=3e-95,
Organism=Escherichia coli, GI1789068, Length=333, Percent_Identity=34.5345345345345, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1787948, Length=332, Percent_Identity=32.5301204819277, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1790369, Length=290, Percent_Identity=31.7241379310345, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1790194, Length=330, Percent_Identity=30.3030303030303, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787906, Length=310, Percent_Identity=29.3548387096774, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787580, Length=320, Percent_Identity=30.3125, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786540, Length=327, Percent_Identity=28.7461773700306, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1790715, Length=309, Percent_Identity=26.2135922330097, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI48994940, Length=327, Percent_Identity=25.3822629969419, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790689, Length=289, Percent_Identity=24.9134948096886, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786268, Length=326, Percent_Identity=20.8588957055215, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36860; Mature: 36729

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIRDVAKLANVSVATVSRVLNHSISVSENTRLVVEQAIAQLYYQPNANAQALAVQNTD
CCHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEECCCCCCEEEEEECCC
TIGVVVTDVTDAFFAILVKAVDKVAEAHQKTILIGIGYHHAEKEREAINTLLRKRCSSLV
EEEEEEECHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
VHSKALSDDELSHYLNTVPGMVIINRVIKGYEHRCVSLDNQKGTYLATEMLIRYGHQHIA
HHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCEEE
YIGSNHAIFDEVERRNGYLAALKDHNYPIIEQAITLNTPDFEGGEKAMIDLLSYNKNLTA
EECCCCHHHHHHHHCCCEEEEEECCCCCHHHHEEEECCCCCCCCHHHHHHHHHCCCCEEE
VVAYNDSMAAGAISVLNENSISVPSQFSIVGFDDMPIARYLIPKLTTIRYPIDLMATYAA
EEEECCCCCHHHHEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHEECCHHHHHHHHH
KLALSLTDEKIITPPMVQFNPTLVRRFSVESKI
HHHEEECCCCCCCCCCCCCCHHHHHEECCCCCC
>Mature Secondary Structure 
STIRDVAKLANVSVATVSRVLNHSISVSENTRLVVEQAIAQLYYQPNANAQALAVQNTD
CHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEECCCCCCEEEEEECCC
TIGVVVTDVTDAFFAILVKAVDKVAEAHQKTILIGIGYHHAEKEREAINTLLRKRCSSLV
EEEEEEECHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
VHSKALSDDELSHYLNTVPGMVIINRVIKGYEHRCVSLDNQKGTYLATEMLIRYGHQHIA
HHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCEEE
YIGSNHAIFDEVERRNGYLAALKDHNYPIIEQAITLNTPDFEGGEKAMIDLLSYNKNLTA
EECCCCHHHHHHHHCCCEEEEEECCCCCHHHHEEEECCCCCCCCHHHHHHHHHCCCCEEE
VVAYNDSMAAGAISVLNENSISVPSQFSIVGFDDMPIARYLIPKLTTIRYPIDLMATYAA
EEEECCCCCHHHHEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHEECCHHHHHHHHH
KLALSLTDEKIITPPMVQFNPTLVRRFSVESKI
HHHEEECCCCCCCCCCCCCCHHHHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1282642; 7542800 [H]