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The map label for this gene is cynR [C]

Identifier: 148827964

GI number: 148827964

Start: 1368722

End: 1369627

Strand: Direct

Name: cynR [C]

Synonym: CGSHiGG_07375

Alternate gene names: 148827964

Gene position: 1368722-1369627 (Clockwise)

Preceding gene: 148827960

Following gene: 148827965

Centisome position: 72.53

GC content: 32.01

Gene sequence:

>906_bases
ATGATGGATATTAGGCATCTAAGATATTTTGTTTCAATCGTAGATAATGATTTTAATTTAAGCCGAGCGTCTCAAAATTT
ATATGTGTCTCAACCTGCATTAAGTATGATGATTACGGAGTTTGAGAATCGTGAAAATATTCAGATATTTAAACGAGCAT
CAGGAAAAATTATTGGACTAACCTTTGCGGGGGAAAATTATTATCGTGATGCAAAAGAAGTGATCAAGCGTTACAATGAT
ATGAGAACAAATCTTTATAAATCAAAAGATTGTAAGAAAGGCACGATAACAATTGGTATTCCTCCCTTAGTTTTATCAGC
CGTGTTCTCTTCTGTATTGCCTCATCTTATTCTTAAGAATCCAGATATTAATTTCATTATTAAAGAAATTGGAGCTTATG
CTCTAAAGAGTGAACTTCTTTTAGATAAAGTTGATTTAGCCGTGTTGTTATATCCCGAGCGAATATCAAAAAATATTATT
GATTCAATTGAAATTCATAGTTCTGAATTAGCCTTATTTCTTTCACCAAAGCATGTTTTAGCAAAAAAACAACAAATCAC
ATGGGCTGATTTACATCAGCAGAAAATGGCAATTTTTGATCAAACATTTATGATTCATCATCATTTGAAGGAAGCTTTTG
AGCGCAATAATTGTTATCCAGATATTGTTTTGGATTCGAGTTGTTGGGATTTTCTGCTAAGTGCGGTCAAAACAAACAAA
GAATTATTAACTATTCTACCGTTACCTATGGCTGAGCTTTATCATTCAAAAGAATTTTTGTGTCGTAAAATCGAAAGTCC
TGTTCCGTGGAAAGTGACACTATGTCGTCAAAGAAAAACGGTCTACACACATCTTGAAGAATATATTTTTGATAAATTAT
TAGAGGCTTTTAGACCAACAAAATAG

Upstream 100 bases:

>100_bases
AGAAATACATCTTTCTTAGGCGGGTATAAGTTATTTTGATAGTGTTTTAAACAATCCTTGTGCTATATTTTGTAAAAATG
GCAGTCTTTAGGGGGTGAAA

Downstream 100 bases:

>100_bases
TTAAAATAAAAGCTTGCAAATAGGGTTGTCTTTCTATAGAATCTACGAGCTCTCAATATGAGAGCCGTTTAATGTAATCA
TTTATTGAACGGGCATGACG

Product: putative HTH-type transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MMDIRHLRYFVSIVDNDFNLSRASQNLYVSQPALSMMITEFENRENIQIFKRASGKIIGLTFAGENYYRDAKEVIKRYND
MRTNLYKSKDCKKGTITIGIPPLVLSAVFSSVLPHLILKNPDINFIIKEIGAYALKSELLLDKVDLAVLLYPERISKNII
DSIEIHSSELALFLSPKHVLAKKQQITWADLHQQKMAIFDQTFMIHHHLKEAFERNNCYPDIVLDSSCWDFLLSAVKTNK
ELLTILPLPMAELYHSKEFLCRKIESPVPWKVTLCRQRKTVYTHLEEYIFDKLLEAFRPTK

Sequences:

>Translated_301_residues
MMDIRHLRYFVSIVDNDFNLSRASQNLYVSQPALSMMITEFENRENIQIFKRASGKIIGLTFAGENYYRDAKEVIKRYND
MRTNLYKSKDCKKGTITIGIPPLVLSAVFSSVLPHLILKNPDINFIIKEIGAYALKSELLLDKVDLAVLLYPERISKNII
DSIEIHSSELALFLSPKHVLAKKQQITWADLHQQKMAIFDQTFMIHHHLKEAFERNNCYPDIVLDSSCWDFLLSAVKTNK
ELLTILPLPMAELYHSKEFLCRKIESPVPWKVTLCRQRKTVYTHLEEYIFDKLLEAFRPTK
>Mature_301_residues
MMDIRHLRYFVSIVDNDFNLSRASQNLYVSQPALSMMITEFENRENIQIFKRASGKIIGLTFAGENYYRDAKEVIKRYND
MRTNLYKSKDCKKGTITIGIPPLVLSAVFSSVLPHLILKNPDINFIIKEIGAYALKSELLLDKVDLAVLLYPERISKNII
DSIEIHSSELALFLSPKHVLAKKQQITWADLHQQKMAIFDQTFMIHHHLKEAFERNNCYPDIVLDSSCWDFLLSAVKTNK
ELLTILPLPMAELYHSKEFLCRKIESPVPWKVTLCRQRKTVYTHLEEYIFDKLLEAFRPTK

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI157672245, Length=247, Percent_Identity=24.2914979757085, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787530, Length=236, Percent_Identity=23.3050847457627, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1788887, Length=224, Percent_Identity=29.0178571428571, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1787879, Length=206, Percent_Identity=24.7572815533981, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI145693105, Length=198, Percent_Identity=26.7676767676768, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790399, Length=199, Percent_Identity=24.1206030150754, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y775_HAEIN (P44876)

Other databases:

- EMBL:   L42023
- PIR:   C64092
- RefSeq:   NP_438934.2
- ProteinModelPortal:   P44876
- GeneID:   950670
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI0775
- TIGR:   HI_0775
- HOGENOM:   HBG494992
- OMA:   CHNGINT
- ProtClustDB:   CLSK797597
- BioCyc:   HINF71421:HI_0775-MONOMER
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate

EC number: NA

Molecular weight: Translated: 35042; Mature: 35042

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDIRHLRYFVSIVDNDFNLSRASQNLYVSQPALSMMITEFENRENIQIFKRASGKIIGL
CCCHHHHHHHHHHHCCCCCCHHCCCCEEEECHHHHHHHHHHCCCCCCEEEEECCCCEEEE
TFAGENYYRDAKEVIKRYNDMRTNLYKSKDCKKGTITIGIPPLVLSAVFSSVLPHLILKN
EECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCC
PDINFIIKEIGAYALKSELLLDKVDLAVLLYPERISKNIIDSIEIHSSELALFLSPKHVL
CCHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHHHHHCCCCCEEEEECCHHHH
AKKQQITWADLHQQKMAIFDQTFMIHHHLKEAFERNNCYPDIVLDSSCWDFLLSAVKTNK
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHCCC
ELLTILPLPMAELYHSKEFLCRKIESPVPWKVTLCRQRKTVYTHLEEYIFDKLLEAFRPT
CEEEEECCCHHHHHCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC
K
C
>Mature Secondary Structure
MMDIRHLRYFVSIVDNDFNLSRASQNLYVSQPALSMMITEFENRENIQIFKRASGKIIGL
CCCHHHHHHHHHHHCCCCCCHHCCCCEEEECHHHHHHHHHHCCCCCCEEEEECCCCEEEE
TFAGENYYRDAKEVIKRYNDMRTNLYKSKDCKKGTITIGIPPLVLSAVFSSVLPHLILKN
EECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCC
PDINFIIKEIGAYALKSELLLDKVDLAVLLYPERISKNIIDSIEIHSSELALFLSPKHVL
CCHHHHHHHHHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHHHHHCCCCCEEEEECCHHHH
AKKQQITWADLHQQKMAIFDQTFMIHHHLKEAFERNNCYPDIVLDSSCWDFLLSAVKTNK
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHCCC
ELLTILPLPMAELYHSKEFLCRKIESPVPWKVTLCRQRKTVYTHLEEYIFDKLLEAFRPT
CEEEEECCCHHHHHCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800