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The map label for this gene is plsB

Identifier: 148827938

GI number: 148827938

Start: 1339460

End: 1341892

Strand: Reverse

Name: plsB

Synonym: CGSHiGG_07235

Alternate gene names: 148827938

Gene position: 1341892-1339460 (Counterclockwise)

Preceding gene: 148827941

Following gene: 148827935

Centisome position: 71.11

GC content: 36.0

Gene sequence:

>2433_bases
ATGGCAAATTTTATAAATATGTATCGCCAATTATTGAGCTTGCCGCTGTCTGCATTGGTGAAAAATAATCCTATTCCCGC
CAATCCAATAGAAGAGCTTTCACTTAATATTCATCAACCTATTGTTTATGTTTTGCCTTATACATCTCAAACTGATTTCG
TTATTTTCCGCCGAAATTGCTTAGCGTTAGGCTTGCCCGATCCCGCAGAGAAAAATGAAATTAATGGCGTTAAGTTACCA
CGTTATGTATATTTAGACGAAGGTCGCCGAATTTTTAAATCAAAAGGTGCAAAAGACGAAACCACTACCATTTTCAATAA
ATATCTTGAATTACACCGCACTTCTGAAAGTTTAGATGTGCAACTTATTCCTGTTTCTGTTCTTTGGGGACGTTCTCCCG
GACAAGAAGATAAATCAGATTTGCCTAATTTGCGTTTATTAAATGGTATACAAAAAACATTTGCAGCAATTTGGTTTGGA
CGTGATACTTTTGTGCGTTTTTCTCAAGCGGTTTCATTACGTTATATGGTAGTTGAACATGGCTCAGATGAAAAAATTGC
ACAAAAGCTGGCTCGAGTTGCAAAAATGCACTTCGCAAAACAACGTATTTCAGCAACAGGTCCTCGTTTACCAAATCGTC
AAGCAATGTTTAATAAATTATTGCAATCAGAAGCAATCCGACGAGCAATTGAAGATGAAGCAAAATCAAAAAATATCAGT
ATTGAAAAAGCACAAAAAGAAGCATATAAAATTTTGGATGAAATTGCAGCTGATGTCAGCCATTCAAGTTTACGTGCAGT
AGATCGTTTTTTACGTTGGCTTTGGAATAAACTTTATTCAGGTATTGATGTACAAAATTCGAATCGTGTCCGTAAATTAG
CGTTAGAAGGTCATGAAATTGTTTATGTGCCTTGCCACCGTAGTCATATTGATTACTTATTGCTTTCTTATGTGCTTTAT
CATCAAGGCCTTGTTCCGCCACATATCGCGGCAGGGATTAACTTAAATTTCTGGCCTATAGGTAGAATGTTTCGTAGTTG
GGGGGCATTCTTTATTCGCCGCACTTTTAAGGGAAATCGACTATATTCTGCCATTTTTCGCGAATATTTATCAGAACTAT
TCCATCGAGGCTATTCCGTCGAATATTTTATTGAGGGCGGTCGTTCTCGTACAGGTCGTTTACTGGCACCAAAAACAGGT
ATGATGTCAATGACACTTCAGGCATTGCAACATAGTCAAACTCGCCCCATTTCGATTGTTCCTGTTTACGTTGGTTATGA
ACACGTATTAGAAGTAGACACTTATGCAAAGGAATTACGTGGTGCAGCGAAAGAAAAAGAAAATGCGGGTTTAGTACTTC
GTGTAATTAAAAAATTACGTAATCTTGGTCAAGGTTTTGTAAATTTTGGTGAGCCAATTACGCTTTCAAACTATTTGAGC
CAACATTTCCCTGATTGGAAAGAGCAAAATCACGAAGAAAAACCACAATGGTTTACACCTGCGGTAAATAATATTTCTAA
ACAAGTAATGATTAATATTAACAAAGCAGCGGCAGTTAATTCAATGAACCTTGTGGGTACAGCACTACTTTCATCTCGTC
AGCGAGCACTTTCACGTGAGCAACTGTTAGAACAACTTAGTAGTTATCAACAATTGTTACAAAATGTCCCTTATTCTACG
GACGTAGTGCTACCAAATGTGACACCGCAAGCAATGTTAGAACACGTATTAGCTTTAGATCGTATAGGTGTGTTAATTGA
AAAAGATAATTTTGGCGAAATTGTACGCTTAGAACGTTCATCTGCTGTACTAATGACTTATTATCGTAATAATATTCAGC
ATCTATTCGTATTACCATCTTTAGTTGCGAGTATTATTTTGCATTACGAAGCGATCCAAAAAGATTTATTATTAGACGCG
ATTAGAAAAATTTACCCTTTCTTACAAGGCGAATTGTTCTTACATTTCAATGAAGATGAATTGAATGTACAAATCCATCA
AATCATTAATGAATTTGCACGCCAAAGCGTTATTAATTCAAATGATAACTTCTTATCTATTAATAAATCAAAAGTACGAA
TTTTACAGCTTTGGTCTGCGGGAACGCGGGAAATCTTGCAACGTTATTACATTACTGTCACTATTTTACAAAAACAACCT
GCTATTTCTCGAGCTGAACTTGAAAAAGAAAGCCAGCTTGTTGCTCAACGTTTATCAGTATTACACGGCATAAATGCACC
AGAATTCTTTGATAAAGCGGTTTTTTCAAGCTTTATTGCAAACTTGAAAGAGCAACGTTACTTTGATGAATCTGGTTATA
CTGTTCTTGATAAAATAGAAGAATTAGCTTCAACGCTTTCCCATTTGATTTCAACAGAAATTTGCTTAACGGTGAAAGGA
ACAATTGAAAAATCCGAAGATCTTTCTTCATAA

Upstream 100 bases:

>100_bases
TAGACGATAAAAACATCAAAGGGCTAAAAATAGTTCTATTCACAAACTGCTTTTAAACGTCTATAAGATCTACAAACTTA
TAACAAAGAGAAAATTTATT

Downstream 100 bases:

>100_bases
AACAATACTGAGGGCATCATTGATGCCCTTTCTTTTATATAAATGATTTAGATCGCATTTAACGAAAAATTATACTTAAT
CAATGCAATTTTAATCTTGG

Product: glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: GPAT

Number of amino acids: Translated: 810; Mature: 809

Protein sequence:

>810_residues
MANFINMYRQLLSLPLSALVKNNPIPANPIEELSLNIHQPIVYVLPYTSQTDFVIFRRNCLALGLPDPAEKNEINGVKLP
RYVYLDEGRRIFKSKGAKDETTTIFNKYLELHRTSESLDVQLIPVSVLWGRSPGQEDKSDLPNLRLLNGIQKTFAAIWFG
RDTFVRFSQAVSLRYMVVEHGSDEKIAQKLARVAKMHFAKQRISATGPRLPNRQAMFNKLLQSEAIRRAIEDEAKSKNIS
IEKAQKEAYKILDEIAADVSHSSLRAVDRFLRWLWNKLYSGIDVQNSNRVRKLALEGHEIVYVPCHRSHIDYLLLSYVLY
HQGLVPPHIAAGINLNFWPIGRMFRSWGAFFIRRTFKGNRLYSAIFREYLSELFHRGYSVEYFIEGGRSRTGRLLAPKTG
MMSMTLQALQHSQTRPISIVPVYVGYEHVLEVDTYAKELRGAAKEKENAGLVLRVIKKLRNLGQGFVNFGEPITLSNYLS
QHFPDWKEQNHEEKPQWFTPAVNNISKQVMININKAAAVNSMNLVGTALLSSRQRALSREQLLEQLSSYQQLLQNVPYST
DVVLPNVTPQAMLEHVLALDRIGVLIEKDNFGEIVRLERSSAVLMTYYRNNIQHLFVLPSLVASIILHYEAIQKDLLLDA
IRKIYPFLQGELFLHFNEDELNVQIHQIINEFARQSVINSNDNFLSINKSKVRILQLWSAGTREILQRYYITVTILQKQP
AISRAELEKESQLVAQRLSVLHGINAPEFFDKAVFSSFIANLKEQRYFDESGYTVLDKIEELASTLSHLISTEICLTVKG
TIEKSEDLSS

Sequences:

>Translated_810_residues
MANFINMYRQLLSLPLSALVKNNPIPANPIEELSLNIHQPIVYVLPYTSQTDFVIFRRNCLALGLPDPAEKNEINGVKLP
RYVYLDEGRRIFKSKGAKDETTTIFNKYLELHRTSESLDVQLIPVSVLWGRSPGQEDKSDLPNLRLLNGIQKTFAAIWFG
RDTFVRFSQAVSLRYMVVEHGSDEKIAQKLARVAKMHFAKQRISATGPRLPNRQAMFNKLLQSEAIRRAIEDEAKSKNIS
IEKAQKEAYKILDEIAADVSHSSLRAVDRFLRWLWNKLYSGIDVQNSNRVRKLALEGHEIVYVPCHRSHIDYLLLSYVLY
HQGLVPPHIAAGINLNFWPIGRMFRSWGAFFIRRTFKGNRLYSAIFREYLSELFHRGYSVEYFIEGGRSRTGRLLAPKTG
MMSMTLQALQHSQTRPISIVPVYVGYEHVLEVDTYAKELRGAAKEKENAGLVLRVIKKLRNLGQGFVNFGEPITLSNYLS
QHFPDWKEQNHEEKPQWFTPAVNNISKQVMININKAAAVNSMNLVGTALLSSRQRALSREQLLEQLSSYQQLLQNVPYST
DVVLPNVTPQAMLEHVLALDRIGVLIEKDNFGEIVRLERSSAVLMTYYRNNIQHLFVLPSLVASIILHYEAIQKDLLLDA
IRKIYPFLQGELFLHFNEDELNVQIHQIINEFARQSVINSNDNFLSINKSKVRILQLWSAGTREILQRYYITVTILQKQP
AISRAELEKESQLVAQRLSVLHGINAPEFFDKAVFSSFIANLKEQRYFDESGYTVLDKIEELASTLSHLISTEICLTVKG
TIEKSEDLSS
>Mature_809_residues
ANFINMYRQLLSLPLSALVKNNPIPANPIEELSLNIHQPIVYVLPYTSQTDFVIFRRNCLALGLPDPAEKNEINGVKLPR
YVYLDEGRRIFKSKGAKDETTTIFNKYLELHRTSESLDVQLIPVSVLWGRSPGQEDKSDLPNLRLLNGIQKTFAAIWFGR
DTFVRFSQAVSLRYMVVEHGSDEKIAQKLARVAKMHFAKQRISATGPRLPNRQAMFNKLLQSEAIRRAIEDEAKSKNISI
EKAQKEAYKILDEIAADVSHSSLRAVDRFLRWLWNKLYSGIDVQNSNRVRKLALEGHEIVYVPCHRSHIDYLLLSYVLYH
QGLVPPHIAAGINLNFWPIGRMFRSWGAFFIRRTFKGNRLYSAIFREYLSELFHRGYSVEYFIEGGRSRTGRLLAPKTGM
MSMTLQALQHSQTRPISIVPVYVGYEHVLEVDTYAKELRGAAKEKENAGLVLRVIKKLRNLGQGFVNFGEPITLSNYLSQ
HFPDWKEQNHEEKPQWFTPAVNNISKQVMININKAAAVNSMNLVGTALLSSRQRALSREQLLEQLSSYQQLLQNVPYSTD
VVLPNVTPQAMLEHVLALDRIGVLIEKDNFGEIVRLERSSAVLMTYYRNNIQHLFVLPSLVASIILHYEAIQKDLLLDAI
RKIYPFLQGELFLHFNEDELNVQIHQIINEFARQSVINSNDNFLSINKSKVRILQLWSAGTREILQRYYITVTILQKQPA
ISRAELEKESQLVAQRLSVLHGINAPEFFDKAVFSSFIANLKEQRYFDESGYTVLDKIEELASTLSHLISTEICLTVKGT
IEKSEDLSS

Specific function: De novo phospholipid biosynthesis; first step. [C]

COG id: COG2937

COG function: function code I; Glycerol-3-phosphate O-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPAT/DAPAT family

Homologues:

Organism=Homo sapiens, GI7657134, Length=471, Percent_Identity=29.2993630573248, Blast_Score=179, Evalue=1e-44,
Organism=Homo sapiens, GI190358539, Length=433, Percent_Identity=24.7113163972286, Blast_Score=125, Evalue=2e-28,
Organism=Escherichia coli, GI87082362, Length=806, Percent_Identity=57.0719602977667, Blast_Score=952, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25147672, Length=283, Percent_Identity=31.8021201413428, Blast_Score=150, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71988723, Length=637, Percent_Identity=23.861852433281, Blast_Score=142, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI71988728, Length=526, Percent_Identity=25.0950570342205, Blast_Score=139, Evalue=6e-33,
Organism=Drosophila melanogaster, GI17864692, Length=277, Percent_Identity=34.6570397111913, Blast_Score=166, Evalue=9e-41,
Organism=Drosophila melanogaster, GI24650754, Length=488, Percent_Identity=27.0491803278689, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI21357731, Length=488, Percent_Identity=27.0491803278689, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24650752, Length=488, Percent_Identity=27.0491803278689, Blast_Score=136, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PLSB_HAEI8 (Q4QMF0)

Other databases:

- EMBL:   CP000057
- RefSeq:   YP_248457.1
- STRING:   Q4QMF0
- GeneID:   3430216
- GenomeReviews:   CP000057_GR
- KEGG:   hit:NTHI0904
- eggNOG:   COG2937
- HOGENOM:   HBG296590
- OMA:   VIYVPCH
- ProtClustDB:   PRK04974
- BioCyc:   HINF281310:NTHI0904-MONOMER
- HAMAP:   MF_00393
- InterPro:   IPR002123
- InterPro:   IPR022284
- SMART:   SM00563
- TIGRFAMs:   TIGR03703

Pfam domain/function: PF01553 Acyltransferase

EC number: =2.3.1.15

Molecular weight: Translated: 92790; Mature: 92659

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANFINMYRQLLSLPLSALVKNNPIPANPIEELSLNIHQPIVYVLPYTSQTDFVIFRRNC
CCHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHCCCCCCCEEEEEECCCCCCEEEEECCE
LALGLPDPAEKNEINGVKLPRYVYLDEGRRIFKSKGAKDETTTIFNKYLELHRTSESLDV
EEECCCCCCCCCCCCCEECCEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEE
QLIPVSVLWGRSPGQEDKSDLPNLRLLNGIQKTFAAIWFGRDTFVRFSQAVSLRYMVVEH
EEEEEEEEECCCCCCCCHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEEEC
GSDEKIAQKLARVAKMHFAKQRISATGPRLPNRQAMFNKLLQSEAIRRAIEDEAKSKNIS
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IEKAQKEAYKILDEIAADVSHSSLRAVDRFLRWLWNKLYSGIDVQNSNRVRKLALEGHEI
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEECCCEE
VYVPCHRSHIDYLLLSYVLYHQGLVPPHIAAGINLNFWPIGRMFRSWGAFFIRRTFKGNR
EEECCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCH
LYSAIFREYLSELFHRGYSVEYFIEGGRSRTGRLLAPKTGMMSMTLQALQHSQTRPISIV
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCCCHHHHHHHHHHCCCCCCEEEE
PVYVGYEHVLEVDTYAKELRGAAKEKENAGLVLRVIKKLRNLGQGFVNFGEPITLSNYLS
EEEECHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHCCCCCEEHHHHHH
QHFPDWKEQNHEEKPQWFTPAVNNISKQVMININKAAAVNSMNLVGTALLSSRQRALSRE
HHCCCHHHCCCCCCCCCCCHHHHCCCEEEEEEECHHHHHCCHHHHHHHHHHHHHHHHHHH
QLLEQLSSYQQLLQNVPYSTDVVLPNVTPQAMLEHVLALDRIGVLIEKDNFGEIVRLERS
HHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHCEEEECCCCCCEEEEECC
SAVLMTYYRNNIQHLFVLPSLVASIILHYEAIQKDLLLDAIRKIYPFLQGELFLHFNEDE
CEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
LNVQIHQIINEFARQSVINSNDNFLSINKSKVRILQLWSAGTREILQRYYITVTILQKQP
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEHHHHCCCHHHHHHHHHEEEEEEECCC
AISRAELEKESQLVAQRLSVLHGINAPEFFDKAVFSSFIANLKEQRYFDESGYTVLDKIE
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
ELASTLSHLISTEICLTVKGTIEKSEDLSS
HHHHHHHHHHHHHEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
ANFINMYRQLLSLPLSALVKNNPIPANPIEELSLNIHQPIVYVLPYTSQTDFVIFRRNC
CHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHCCCCCCCEEEEEECCCCCCEEEEECCE
LALGLPDPAEKNEINGVKLPRYVYLDEGRRIFKSKGAKDETTTIFNKYLELHRTSESLDV
EEECCCCCCCCCCCCCEECCEEEEECCCHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEE
QLIPVSVLWGRSPGQEDKSDLPNLRLLNGIQKTFAAIWFGRDTFVRFSQAVSLRYMVVEH
EEEEEEEEECCCCCCCCHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEEEC
GSDEKIAQKLARVAKMHFAKQRISATGPRLPNRQAMFNKLLQSEAIRRAIEDEAKSKNIS
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IEKAQKEAYKILDEIAADVSHSSLRAVDRFLRWLWNKLYSGIDVQNSNRVRKLALEGHEI
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEECCCEE
VYVPCHRSHIDYLLLSYVLYHQGLVPPHIAAGINLNFWPIGRMFRSWGAFFIRRTFKGNR
EEECCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEHHHHHHHHHHHHHHHHHCCCCH
LYSAIFREYLSELFHRGYSVEYFIEGGRSRTGRLLAPKTGMMSMTLQALQHSQTRPISIV
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCCCHHHHHHHHHHCCCCCCEEEE
PVYVGYEHVLEVDTYAKELRGAAKEKENAGLVLRVIKKLRNLGQGFVNFGEPITLSNYLS
EEEECHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHCCCCCEEHHHHHH
QHFPDWKEQNHEEKPQWFTPAVNNISKQVMININKAAAVNSMNLVGTALLSSRQRALSRE
HHCCCHHHCCCCCCCCCCCHHHHCCCEEEEEEECHHHHHCCHHHHHHHHHHHHHHHHHHH
QLLEQLSSYQQLLQNVPYSTDVVLPNVTPQAMLEHVLALDRIGVLIEKDNFGEIVRLERS
HHHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHCEEEECCCCCCEEEEECC
SAVLMTYYRNNIQHLFVLPSLVASIILHYEAIQKDLLLDAIRKIYPFLQGELFLHFNEDE
CEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
LNVQIHQIINEFARQSVINSNDNFLSINKSKVRILQLWSAGTREILQRYYITVTILQKQP
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEHHHHCCCHHHHHHHHHEEEEEEECCC
AISRAELEKESQLVAQRLSVLHGINAPEFFDKAVFSSFIANLKEQRYFDESGYTVLDKIE
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
ELASTLSHLISTEICLTVKGTIEKSEDLSS
HHHHHHHHHHHHHEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA