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The map label for this gene is cyaY [H]

Identifier: 148827918

GI number: 148827918

Start: 1312077

End: 1313936

Strand: Direct

Name: cyaY [H]

Synonym: CGSHiGG_07105

Alternate gene names: 148827918

Gene position: 1312077-1313936 (Clockwise)

Preceding gene: 148827917

Following gene: 148827919

Centisome position: 69.53

GC content: 39.78

Gene sequence:

>1860_bases
ATGCTGGATTCTCCTTTACCATCAAAAATAATAGAAAAACCGACCGCACTTTCTGTTTTGAAATCGGTTTTCGGTTATCA
ATCTTTCCGTAAAGGGCAGGAAGAAGTCATTAATGCCACTTTAAATGGACAAGATGCTTTGGTGGTAATGGCAACGGGGA
ATGGCAAATCGCTTTGTTACCAAATTCCCGCACTTTGTTTTGATGGTTTAACTTTAGTGATTTCTCCGCTGATTTCCTTG
ATGAAAGATCAAGTGGATCAGCTGCAAGCTAATGGAATTGAGGCGGATTTTCTTAATTCTAGTCAGACTTTAGCACAGCA
GCAACAAGTACAAAATAAGCTTATTTCTGGGCAACTTAAACTACTTTATGTGTCGCCAGAAAAAGTGATGACGAACAGTT
TCTTTCAACTTATTTCTTATAGCAAAGTCTGCTTTATTGCGATTGATGAAGCACATTGTATTTCTCAATGGGGGCATGAC
TTTCGCCCTGAATATACCCAGCTTGGCGGTTTAAAAGCCAGTTTCCCTGATGCGCCGATTATGGCACTTACGGCAACGGC
AGATTATGCGACTCAACAAGATATTCTGCGGCATCTTAATCTTAAAAATCTGCACAAATACATTGGTAGTTTTGATCGAC
CAAATATTCGTTATACCTTGGAAGAAAAATACAAACCTATGGAGCAACTGACACGTTTTGTGTTGGCTCAAAAGGGTAAG
AGTGGGATTATTTATTGCAACAGCAGAAATAAGGTTGAGCGAATTGCGGAAAGTTTACGCAATAAAGGTGTCTCTGCTGC
TGCTTACCACGCAGGAATGGAAACGGCAATTCGTGAACGTGTGCAACAGGATTTTCAGCGTGATAATGTTCAAGTAGTAG
TCGCAACCATTGCTTTTGGAATGGGGATTAATAAATCCAATGTGCGCTTTGTTGCCCATTTTGATTTACCACGTAGCATT
GAATCTTACTATCAAGAAACAGGTCGAGCAGGACGTGATGATTTGCCTGCCGAGGCGGTTTTGTTTTATGAACCAGCTGA
TTACGCTTGGTTACAAAAAATTCTCTTCGAAAAACCAGAAACGCCACAGCGTCAGATTGAGCAACATAAATTAGAAGCTA
TTGGGGAATTTGCGGAAAGCCAGACTTGTCGCCGTTTAGTTCTTCTCAATTATTTTGGCGAGCATCGACAAACACCATGC
AATAACTGTGATATTTGCCTTGATCCTCCTAAAAAATATGATGGTTTAGTCGATGCGCAAAAAGTAATGTCTACTATTTA
TCGAGTGGGACAATGTTTTGGTGCACATTATGTGATTGCGGTGTTGCGTGGCATGCACAATCAGAAAATTATTGAACGCC
AACACCATAAACTTTCAGTGTATGGCATTGGAAAAGATAAAAGTAAAGAGCATTGGCAGTCCGTCATTCGTCAGCTTATT
CATTTGGGTTTTGTGCAACAGGTTATTAGTGAATTAAATCCAACGTTGCAACTTACTGAAAGTGCGAAAGTGATTTTGAA
AGGCGAAGAACCGTTAGAATTGGCAATGCCTCGTATTTCTGCAATCAGTAAAATTGCTCATAATCCACAACGTCAAGGTG
TTGCAAATTACGATAAGGATTTATTTGCACGCTTGCGTTTCTTACGCAAACAAATTGCCGATAAAGAAAATATTCCGCCG
TACATTGTCTTTAATGATGCGACGTTGCAAGAAATGGCACAATATATGCCAACAAGCAATATTGAAATGTTGCAAATTAA
TGGCGTGGGTTCTATCAAATTAGAACGGTTTGGGCAGCCGTTTATGGCATTGATTCAAGAACATAAGGCAATTTTGGCGA
ATGCGCAAAATAATGACTAA

Upstream 100 bases:

>100_bases
GCTTTTAAAAATGGCGACTGGGTTTCTAATGACGGACAACGTTTTTGGGATTGTTTCGTTGAAGCCTGTGCTGCACATGG
CGAGAACGTGCAGTTCTAAA

Downstream 100 bases:

>100_bases
GTGTTAAAAGTGCGGTTAAAAATGACCGCACTTTTTGTTATACTTGCGCCAATTTTTTCAGTTCTTAGAATTTAAGGTTA
AACAATGCGTACAAGTCAAT

Product: frataxin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 619; Mature: 619

Protein sequence:

>619_residues
MLDSPLPSKIIEKPTALSVLKSVFGYQSFRKGQEEVINATLNGQDALVVMATGNGKSLCYQIPALCFDGLTLVISPLISL
MKDQVDQLQANGIEADFLNSSQTLAQQQQVQNKLISGQLKLLYVSPEKVMTNSFFQLISYSKVCFIAIDEAHCISQWGHD
FRPEYTQLGGLKASFPDAPIMALTATADYATQQDILRHLNLKNLHKYIGSFDRPNIRYTLEEKYKPMEQLTRFVLAQKGK
SGIIYCNSRNKVERIAESLRNKGVSAAAYHAGMETAIRERVQQDFQRDNVQVVVATIAFGMGINKSNVRFVAHFDLPRSI
ESYYQETGRAGRDDLPAEAVLFYEPADYAWLQKILFEKPETPQRQIEQHKLEAIGEFAESQTCRRLVLLNYFGEHRQTPC
NNCDICLDPPKKYDGLVDAQKVMSTIYRVGQCFGAHYVIAVLRGMHNQKIIERQHHKLSVYGIGKDKSKEHWQSVIRQLI
HLGFVQQVISELNPTLQLTESAKVILKGEEPLELAMPRISAISKIAHNPQRQGVANYDKDLFARLRFLRKQIADKENIPP
YIVFNDATLQEMAQYMPTSNIEMLQINGVGSIKLERFGQPFMALIQEHKAILANAQNND

Sequences:

>Translated_619_residues
MLDSPLPSKIIEKPTALSVLKSVFGYQSFRKGQEEVINATLNGQDALVVMATGNGKSLCYQIPALCFDGLTLVISPLISL
MKDQVDQLQANGIEADFLNSSQTLAQQQQVQNKLISGQLKLLYVSPEKVMTNSFFQLISYSKVCFIAIDEAHCISQWGHD
FRPEYTQLGGLKASFPDAPIMALTATADYATQQDILRHLNLKNLHKYIGSFDRPNIRYTLEEKYKPMEQLTRFVLAQKGK
SGIIYCNSRNKVERIAESLRNKGVSAAAYHAGMETAIRERVQQDFQRDNVQVVVATIAFGMGINKSNVRFVAHFDLPRSI
ESYYQETGRAGRDDLPAEAVLFYEPADYAWLQKILFEKPETPQRQIEQHKLEAIGEFAESQTCRRLVLLNYFGEHRQTPC
NNCDICLDPPKKYDGLVDAQKVMSTIYRVGQCFGAHYVIAVLRGMHNQKIIERQHHKLSVYGIGKDKSKEHWQSVIRQLI
HLGFVQQVISELNPTLQLTESAKVILKGEEPLELAMPRISAISKIAHNPQRQGVANYDKDLFARLRFLRKQIADKENIPP
YIVFNDATLQEMAQYMPTSNIEMLQINGVGSIKLERFGQPFMALIQEHKAILANAQNND
>Mature_619_residues
MLDSPLPSKIIEKPTALSVLKSVFGYQSFRKGQEEVINATLNGQDALVVMATGNGKSLCYQIPALCFDGLTLVISPLISL
MKDQVDQLQANGIEADFLNSSQTLAQQQQVQNKLISGQLKLLYVSPEKVMTNSFFQLISYSKVCFIAIDEAHCISQWGHD
FRPEYTQLGGLKASFPDAPIMALTATADYATQQDILRHLNLKNLHKYIGSFDRPNIRYTLEEKYKPMEQLTRFVLAQKGK
SGIIYCNSRNKVERIAESLRNKGVSAAAYHAGMETAIRERVQQDFQRDNVQVVVATIAFGMGINKSNVRFVAHFDLPRSI
ESYYQETGRAGRDDLPAEAVLFYEPADYAWLQKILFEKPETPQRQIEQHKLEAIGEFAESQTCRRLVLLNYFGEHRQTPC
NNCDICLDPPKKYDGLVDAQKVMSTIYRVGQCFGAHYVIAVLRGMHNQKIIERQHHKLSVYGIGKDKSKEHWQSVIRQLI
HLGFVQQVISELNPTLQLTESAKVILKGEEPLELAMPRISAISKIAHNPQRQGVANYDKDLFARLRFLRKQIADKENIPP
YIVFNDATLQEMAQYMPTSNIEMLQINGVGSIKLERFGQPFMALIQEHKAILANAQNND

Specific function: DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI169218196, Length=691, Percent_Identity=32.1273516642547, Blast_Score=331, Evalue=1e-90,
Organism=Homo sapiens, GI110735439, Length=553, Percent_Identity=36.3471971066908, Blast_Score=327, Evalue=2e-89,
Organism=Homo sapiens, GI4557365, Length=654, Percent_Identity=32.8746177370031, Blast_Score=320, Evalue=2e-87,
Organism=Homo sapiens, GI14591902, Length=403, Percent_Identity=40.6947890818859, Blast_Score=310, Evalue=3e-84,
Organism=Homo sapiens, GI14591904, Length=403, Percent_Identity=40.6947890818859, Blast_Score=310, Evalue=3e-84,
Organism=Homo sapiens, GI148612816, Length=423, Percent_Identity=39.0070921985816, Blast_Score=284, Evalue=2e-76,
Organism=Homo sapiens, GI51242947, Length=353, Percent_Identity=43.0594900849858, Blast_Score=275, Evalue=1e-73,
Organism=Homo sapiens, GI51242943, Length=353, Percent_Identity=43.0594900849858, Blast_Score=275, Evalue=1e-73,
Organism=Homo sapiens, GI284005309, Length=371, Percent_Identity=38.8140161725067, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI148613856, Length=326, Percent_Identity=22.6993865030675, Blast_Score=76, Evalue=9e-14,
Organism=Homo sapiens, GI38201710, Length=326, Percent_Identity=22.6993865030675, Blast_Score=76, Evalue=9e-14,
Organism=Homo sapiens, GI4758138, Length=328, Percent_Identity=22.5609756097561, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI13514831, Length=376, Percent_Identity=24.468085106383, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI55749865, Length=335, Percent_Identity=21.4925373134328, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI262118318, Length=350, Percent_Identity=22, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI20149629, Length=360, Percent_Identity=22.2222222222222, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI216548263, Length=350, Percent_Identity=22.2857142857143, Blast_Score=67, Evalue=7e-11,
Organism=Homo sapiens, GI262231852, Length=350, Percent_Identity=22.2857142857143, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI48994977, Length=593, Percent_Identity=63.4064080944351, Blast_Score=786, Evalue=0.0,
Organism=Escherichia coli, GI87082221, Length=342, Percent_Identity=23.6842105263158, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1787016, Length=353, Percent_Identity=20.9631728045326, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1787605, Length=344, Percent_Identity=23.2558139534884, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25145561, Length=646, Percent_Identity=33.28173374613, Blast_Score=330, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI71987997, Length=407, Percent_Identity=40.5405405405405, Blast_Score=305, Evalue=4e-83,
Organism=Caenorhabditis elegans, GI71987993, Length=407, Percent_Identity=40.5405405405405, Blast_Score=305, Evalue=4e-83,
Organism=Caenorhabditis elegans, GI32564293, Length=687, Percent_Identity=30.4221251819505, Blast_Score=297, Evalue=9e-81,
Organism=Caenorhabditis elegans, GI17552866, Length=437, Percent_Identity=35.9267734553776, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI17537549, Length=390, Percent_Identity=22.8205128205128, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17552114, Length=333, Percent_Identity=23.4234234234234, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71987143, Length=113, Percent_Identity=28.3185840707965, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=489, Percent_Identity=38.0368098159509, Blast_Score=325, Evalue=1e-89,
Organism=Saccharomyces cerevisiae, GI6320224, Length=367, Percent_Identity=22.6158038147139, Blast_Score=81, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6320041, Length=334, Percent_Identity=23.3532934131737, Blast_Score=81, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324217, Length=324, Percent_Identity=22.2222222222222, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24646066, Length=627, Percent_Identity=35.8851674641148, Blast_Score=364, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24664226, Length=461, Percent_Identity=35.5748373101952, Blast_Score=285, Evalue=7e-77,
Organism=Drosophila melanogaster, GI62472181, Length=452, Percent_Identity=35.8407079646018, Blast_Score=283, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24664230, Length=452, Percent_Identity=35.8407079646018, Blast_Score=282, Evalue=4e-76,
Organism=Drosophila melanogaster, GI21358123, Length=365, Percent_Identity=39.4520547945205, Blast_Score=233, Evalue=3e-61,
Organism=Drosophila melanogaster, GI24583281, Length=334, Percent_Identity=22.7544910179641, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24583279, Length=334, Percent_Identity=22.7544910179641, Blast_Score=76, Evalue=9e-14,
Organism=Drosophila melanogaster, GI18857967, Length=402, Percent_Identity=21.8905472636816, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28574962, Length=323, Percent_Identity=22.2910216718266, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24644487, Length=343, Percent_Identity=22.1574344023324, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45551833, Length=343, Percent_Identity=22.1574344023324, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24644485, Length=343, Percent_Identity=22.1574344023324, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24644483, Length=343, Percent_Identity=22.1574344023324, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI281361218, Length=343, Percent_Identity=22.1574344023324, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644481, Length=343, Percent_Identity=22.1574344023324, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644479, Length=343, Percent_Identity=22.1574344023324, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 70046; Mature: 70046

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDSPLPSKIIEKPTALSVLKSVFGYQSFRKGQEEVINATLNGQDALVVMATGNGKSLCY
CCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHEECCCCEEEEEEECCCCHHHH
QIPALCFDGLTLVISPLISLMKDQVDQLQANGIEADFLNSSQTLAQQQQVQNKLISGQLK
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHCCCEE
LLYVSPEKVMTNSFFQLISYSKVCFIAIDEAHCISQWGHDFRPEYTQLGGLKASFPDAPI
EEEECHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCE
MALTATADYATQQDILRHLNLKNLHKYIGSFDRPNIRYTLEEKYKPMEQLTRFVLAQKGK
EEEEECHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEHHHHCCHHHHHHHHHHHHCCC
SGIIYCNSRNKVERIAESLRNKGVSAAAYHAGMETAIRERVQQDFQRDNVQVVVATIAFG
CCEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHH
MGINKSNVRFVAHFDLPRSIESYYQETGRAGRDDLPAEAVLFYEPADYAWLQKILFEKPE
CCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCC
TPQRQIEQHKLEAIGEFAESQTCRRLVLLNYFGEHRQTPCNNCDICLDPPKKYDGLVDAQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCHHHCCHHHHH
KVMSTIYRVGQCFGAHYVIAVLRGMHNQKIIERQHHKLSVYGIGKDKSKEHWQSVIRQLI
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHH
HLGFVQQVISELNPTLQLTESAKVILKGEEPLELAMPRISAISKIAHNPQRQGVANYDKD
HHHHHHHHHHHCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHCCCHHCCCCCCCHH
LFARLRFLRKQIADKENIPPYIVFNDATLQEMAQYMPTSNIEMLQINGVGSIKLERFGQP
HHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHCCCCCCEEEEECCCCCEEHHHCCCH
FMALIQEHKAILANAQNND
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLDSPLPSKIIEKPTALSVLKSVFGYQSFRKGQEEVINATLNGQDALVVMATGNGKSLCY
CCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHEECCCCEEEEEEECCCCHHHH
QIPALCFDGLTLVISPLISLMKDQVDQLQANGIEADFLNSSQTLAQQQQVQNKLISGQLK
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHCCCEE
LLYVSPEKVMTNSFFQLISYSKVCFIAIDEAHCISQWGHDFRPEYTQLGGLKASFPDAPI
EEEECHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCE
MALTATADYATQQDILRHLNLKNLHKYIGSFDRPNIRYTLEEKYKPMEQLTRFVLAQKGK
EEEEECHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEHHHHCCHHHHHHHHHHHHCCC
SGIIYCNSRNKVERIAESLRNKGVSAAAYHAGMETAIRERVQQDFQRDNVQVVVATIAFG
CCEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHH
MGINKSNVRFVAHFDLPRSIESYYQETGRAGRDDLPAEAVLFYEPADYAWLQKILFEKPE
CCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCC
TPQRQIEQHKLEAIGEFAESQTCRRLVLLNYFGEHRQTPCNNCDICLDPPKKYDGLVDAQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCHHHCCHHHHH
KVMSTIYRVGQCFGAHYVIAVLRGMHNQKIIERQHHKLSVYGIGKDKSKEHWQSVIRQLI
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHH
HLGFVQQVISELNPTLQLTESAKVILKGEEPLELAMPRISAISKIAHNPQRQGVANYDKD
HHHHHHHHHHHCCCCEEECCCCEEEEECCCCHHHHHHHHHHHHHHHCCCHHCCCCCCCHH
LFARLRFLRKQIADKENIPPYIVFNDATLQEMAQYMPTSNIEMLQINGVGSIKLERFGQP
HHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHCCCCCCEEEEECCCCCEEHHHCCCH
FMALIQEHKAILANAQNND
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]