| Definition | Haemophilus influenzae PittGG chromosome, complete genome. |
|---|---|
| Accession | NC_009567 |
| Length | 1,887,192 |
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The map label for this gene is cyaA [H]
Identifier: 148827896
GI number: 148827896
Start: 1278736
End: 1281267
Strand: Direct
Name: cyaA [H]
Synonym: CGSHiGG_06955
Alternate gene names: 148827896
Gene position: 1278736-1281267 (Clockwise)
Preceding gene: 148827893
Following gene: 148827897
Centisome position: 67.76
GC content: 38.7
Gene sequence:
>2532_bases GTGGAATGTAATCTAGCACAAGCAAAACAATGGGTTAGCGCCTTGGATCAACGCCGTTTTGAGCGTGCATTACAAGGTTC AGGCGATGCATTCCAACACGTTTTAGCGATTGCACCTTTACTTCTACACCTAAACCATCCGCAACTTCCCGGCTATGTTA TTCACGCCCCCTCTGGCATTGCGAATTTCCTTGCTTCTGATTATCAAAAAAAATGGCTCACCAATGAATACGGTATTCAC TATGCCGATCATAAGCCATCAACACTCAAAAGTGCGGTAAATTTTCACGAAGTTTTTCCACCAATTTTAGGTGTTTATGT AATGGGTAGCTTTGGCTCAATAAGTCAAACGTCCTCTTCAGATCTTGATACTTGGATTTGTGTCCGTGATGGCTTGAGTC CAGATGAATATACACTTCTTACTCAAAAAGCCAAGCGGATTAGTGAATGGGCAATGCAATTTAATGTGGAAATTAATTTT TATCTGATGGATCAACAACGTTTCCGCAATGAACATTATGCTGACCCACTAACTATTGAAAATAGCGGCTCTGCGCAATA TATGTTATTGCTTGATGAGTTCTATCGCTCCGCCGTACGCTTAGCGGGTAAACCTCTACTTTGGTTGCATTTATGGGTGG AAAATGAAAAAGACTATGAAAAAGAGGTCGCTCGTTTAATTACGGAAGGGGAAATTGATCCAAATGATTGGGTAGATTTC GGCGGTTTAGGACAATTTTCTGCAAACGAATATTTCGGTGCCAGTTTATGGCATCTTTATAAAGGGATTGATTCACCTTA TAAATCTGTGCTCAAAATTTTGTTGTTGGAAGCCTATTCCAAGGAATACCCAAACACTTGCTTAATTGCCCGCACTTTTA AGCGAGATTTACTTGCAGGCAATACCAATCCTGATCACCATTTTGATCCTTACATTGCCATTCTTGCAAAAGTAACCCAA TATTTAACCGCACTTTCTGAATTTAAACGTTTGGATTTTGTGCACCGTTGTTTCTATGTGAAAGCAACGGAAGATTTTGC GCGTTATCAAGCCAATAATTGGCGTATTCGTTATATGGAAATACTTGCGCAAGAATGGGGATGGTCTGCAGAAACGGTAA AACATCTCAATAAGCGTCCATTTTGGAAAATTAAGGCAGTAAAAGAAAACCACGATAACATAATGAAATTTTTAATGTTG AGTTATCGTAATTTAGTGGAATTTGCTCGAAAGCATCACATTCACTCGAGCGTCGTGCCACAAGATATCAACATTCTTTC TCGTAAACTTTATACTGCTTTTGAAGAACTTCCCGGCAAAGTGTCCTTACTCAACACACAGATATCTCACAATTTATCAG AAGCACACCTGACTTTTGTGGAAGTTCGTGGCAATAAACATTTTAAAGATGGTTGGTACCTTATCAATCAACCAATACAC CATATTATGTTCTCCAAAGAACGGGTGATTGAATATGGAGAAAGCCTGAATAAATTAGTTTCTTGGGCTTATTTCAATCA TTTACTCACTGAAAAAACCGAATTGTCAATTTTTAGCAAGAATGTGATTTTAAGTACATTACAAAGCTTTGTCACTAACT TACGTCAGTCTTTTCCAAGCACCATCGCCAAACAACCTAAAAATAGCGATTTATTGAATCAATGTGAAATTCGTAGCTTG TTTATTGCCATAAATCTCACGACCGATCCAACATCCAAAGTAGAAGAAGTATTAACGGGTATTTCATCGCGAGATTTATT TAGTTTTGGATCGCTCGAGCAAAGCCTTGTGGGCAGTATCGATTTTACTTATCGTAACGTGTGGAACGAAATCCGAACGC TCCATTTTGAAGGGCAAAATGCCATTTTGCTTGCGCTAAAAGTACTTTCTAACAAAATTTATCGTGGCGTTAATCGCCCA GATTCCATCCAAGTCTATTGCTATAGCGAACGTTATCGCCAAGATTTACGTCAATTAGTGATGGGATTAGTCAATCGATG CGTTAGCATCCAAGTAGGCGATATTCAACAACCTTGCCAAACGTCACGTTTACGCGTAGCGGGTAAAAACTGGCAATTAT TTTTTGAAGATCGCGGCATCAGCTTACAAGAAATCGGAAATGAATCGGTCTGTAATGACGCTGAAAGTGCGGTGGATTTT GACGAAGTTTTACAAACACCAATTGAAGATGGCGAGACAAACCAAGAAAGTCGTCGCTATCCACCAGAAATGGATGCCTT CGCCAGTGAAGGATTCCTACAATTCTTTTTTGAAGATAATTCTGATCACAGCTTCAATGTTTATATTTTAGATGAATCTA ATCATCTCGAAATCTATCGCCACTGCGATGGTGAAAAAGATGAAAAAGTGCGGGAGATTAATCAACTTTATCAAAACGCC AAACAGGAAGGCGATAAAAATCCTTACAATATCGTTCAACATAATTTTAACTACCCTCAATTTTATCAACTACAAAATGG AAAAAATGGCATATCCATCGTGCCGTTTAAATTCCGCCAAATGAATAAGTAA
Upstream 100 bases:
>100_bases ATATTTTAAAAAATTGTGATTTATGTCACATTTTTTTGCATTTATACTCCCTAAGTGGTAAATTGTTCGCCAATTTTTGT TGTTCTGGTAGGGACACCAC
Downstream 100 bases:
>100_bases TATTTTCCTGTGGTTGATAGGTTACCGAAAGATATCTATACTTATTTCCTCTTTTACTAGATAAATTGTAGATATGATAA CTTCGCAAACACCAATTACT
Product: adenylate cyclase
Products: NA
Alternate protein names: ATP pyrophosphate-lyase; Adenylyl cyclase [H]
Number of amino acids: Translated: 843; Mature: 843
Protein sequence:
>843_residues MECNLAQAKQWVSALDQRRFERALQGSGDAFQHVLAIAPLLLHLNHPQLPGYVIHAPSGIANFLASDYQKKWLTNEYGIH YADHKPSTLKSAVNFHEVFPPILGVYVMGSFGSISQTSSSDLDTWICVRDGLSPDEYTLLTQKAKRISEWAMQFNVEINF YLMDQQRFRNEHYADPLTIENSGSAQYMLLLDEFYRSAVRLAGKPLLWLHLWVENEKDYEKEVARLITEGEIDPNDWVDF GGLGQFSANEYFGASLWHLYKGIDSPYKSVLKILLLEAYSKEYPNTCLIARTFKRDLLAGNTNPDHHFDPYIAILAKVTQ YLTALSEFKRLDFVHRCFYVKATEDFARYQANNWRIRYMEILAQEWGWSAETVKHLNKRPFWKIKAVKENHDNIMKFLML SYRNLVEFARKHHIHSSVVPQDINILSRKLYTAFEELPGKVSLLNTQISHNLSEAHLTFVEVRGNKHFKDGWYLINQPIH HIMFSKERVIEYGESLNKLVSWAYFNHLLTEKTELSIFSKNVILSTLQSFVTNLRQSFPSTIAKQPKNSDLLNQCEIRSL FIAINLTTDPTSKVEEVLTGISSRDLFSFGSLEQSLVGSIDFTYRNVWNEIRTLHFEGQNAILLALKVLSNKIYRGVNRP DSIQVYCYSERYRQDLRQLVMGLVNRCVSIQVGDIQQPCQTSRLRVAGKNWQLFFEDRGISLQEIGNESVCNDAESAVDF DEVLQTPIEDGETNQESRRYPPEMDAFASEGFLQFFFEDNSDHSFNVYILDESNHLEIYRHCDGEKDEKVREINQLYQNA KQEGDKNPYNIVQHNFNYPQFYQLQNGKNGISIVPFKFRQMNK
Sequences:
>Translated_843_residues MECNLAQAKQWVSALDQRRFERALQGSGDAFQHVLAIAPLLLHLNHPQLPGYVIHAPSGIANFLASDYQKKWLTNEYGIH YADHKPSTLKSAVNFHEVFPPILGVYVMGSFGSISQTSSSDLDTWICVRDGLSPDEYTLLTQKAKRISEWAMQFNVEINF YLMDQQRFRNEHYADPLTIENSGSAQYMLLLDEFYRSAVRLAGKPLLWLHLWVENEKDYEKEVARLITEGEIDPNDWVDF GGLGQFSANEYFGASLWHLYKGIDSPYKSVLKILLLEAYSKEYPNTCLIARTFKRDLLAGNTNPDHHFDPYIAILAKVTQ YLTALSEFKRLDFVHRCFYVKATEDFARYQANNWRIRYMEILAQEWGWSAETVKHLNKRPFWKIKAVKENHDNIMKFLML SYRNLVEFARKHHIHSSVVPQDINILSRKLYTAFEELPGKVSLLNTQISHNLSEAHLTFVEVRGNKHFKDGWYLINQPIH HIMFSKERVIEYGESLNKLVSWAYFNHLLTEKTELSIFSKNVILSTLQSFVTNLRQSFPSTIAKQPKNSDLLNQCEIRSL FIAINLTTDPTSKVEEVLTGISSRDLFSFGSLEQSLVGSIDFTYRNVWNEIRTLHFEGQNAILLALKVLSNKIYRGVNRP DSIQVYCYSERYRQDLRQLVMGLVNRCVSIQVGDIQQPCQTSRLRVAGKNWQLFFEDRGISLQEIGNESVCNDAESAVDF DEVLQTPIEDGETNQESRRYPPEMDAFASEGFLQFFFEDNSDHSFNVYILDESNHLEIYRHCDGEKDEKVREINQLYQNA KQEGDKNPYNIVQHNFNYPQFYQLQNGKNGISIVPFKFRQMNK >Mature_843_residues MECNLAQAKQWVSALDQRRFERALQGSGDAFQHVLAIAPLLLHLNHPQLPGYVIHAPSGIANFLASDYQKKWLTNEYGIH YADHKPSTLKSAVNFHEVFPPILGVYVMGSFGSISQTSSSDLDTWICVRDGLSPDEYTLLTQKAKRISEWAMQFNVEINF YLMDQQRFRNEHYADPLTIENSGSAQYMLLLDEFYRSAVRLAGKPLLWLHLWVENEKDYEKEVARLITEGEIDPNDWVDF GGLGQFSANEYFGASLWHLYKGIDSPYKSVLKILLLEAYSKEYPNTCLIARTFKRDLLAGNTNPDHHFDPYIAILAKVTQ YLTALSEFKRLDFVHRCFYVKATEDFARYQANNWRIRYMEILAQEWGWSAETVKHLNKRPFWKIKAVKENHDNIMKFLML SYRNLVEFARKHHIHSSVVPQDINILSRKLYTAFEELPGKVSLLNTQISHNLSEAHLTFVEVRGNKHFKDGWYLINQPIH HIMFSKERVIEYGESLNKLVSWAYFNHLLTEKTELSIFSKNVILSTLQSFVTNLRQSFPSTIAKQPKNSDLLNQCEIRSL FIAINLTTDPTSKVEEVLTGISSRDLFSFGSLEQSLVGSIDFTYRNVWNEIRTLHFEGQNAILLALKVLSNKIYRGVNRP DSIQVYCYSERYRQDLRQLVMGLVNRCVSIQVGDIQQPCQTSRLRVAGKNWQLFFEDRGISLQEIGNESVCNDAESAVDF DEVLQTPIEDGETNQESRRYPPEMDAFASEGFLQFFFEDNSDHSFNVYILDESNHLEIYRHCDGEKDEKVREINQLYQNA KQEGDKNPYNIVQHNFNYPQFYQLQNGKNGISIVPFKFRQMNK
Specific function: Plays an essential role in competence development [H]
COG id: COG3072
COG function: function code F; Adenylate cyclase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the adenylyl cyclase class-1 family [H]
Homologues:
Organism=Escherichia coli, GI1790238, Length=848, Percent_Identity=42.0990566037736, Blast_Score=654, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000274 [H]
Pfam domain/function: PF01295 Adenylate_cycl [H]
EC number: =4.6.1.1 [H]
Molecular weight: Translated: 97840; Mature: 97840
Theoretical pI: Translated: 6.54; Mature: 6.54
Prosite motif: PS00589 PTS_HPR_SER ; PS01092 ADENYLATE_CYCLASE_1_1 ; PS01093 ADENYLATE_CYCLASE_1_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MECNLAQAKQWVSALDQRRFERALQGSGDAFQHVLAIAPLLLHLNHPQLPGYVIHAPSGI CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHH ANFLASDYQKKWLTNEYGIHYADHKPSTLKSAVNFHEVFPPILGVYVMGSFGSISQTSSS HHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC DLDTWICVRDGLSPDEYTLLTQKAKRISEWAMQFNVEINFYLMDQQRFRNEHYADPLTIE CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEEEECHHHHCCCCCCCCEEEE NSGSAQYMLLLDEFYRSAVRLAGKPLLWLHLWVENEKDYEKEVARLITEGEIDPNDWVDF CCCCCEEEHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCC GGLGQFSANEYFGASLWHLYKGIDSPYKSVLKILLLEAYSKEYPNTCLIARTFKRDLLAG CCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCC NTNPDHHFDPYIAILAKVTQYLTALSEFKRLDFVHRCFYVKATEDFARYQANNWRIRYME CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHCCCCCEEHHHH ILAQEWGWSAETVKHLNKRPFWKIKAVKENHDNIMKFLMLSYRNLVEFARKHHIHSSVVP HHHHHHCCCHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC QDINILSRKLYTAFEELPGKVSLLNTQISHNLSEAHLTFVEVRGNKHFKDGWYLINQPIH CHHHHHHHHHHHHHHHCCCCEEEEHHHHHCCCCHHEEEEEEEECCCCCCCCCEEECCCHH HIMFSKERVIEYGESLNKLVSWAYFNHLLTEKTELSIFSKNVILSTLQSFVTNLRQSFPS HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCH TIAKQPKNSDLLNQCEIRSLFIAINLTTDPTSKVEEVLTGISSRDLFSFGSLEQSLVGSI HHHCCCCCCCHHHHHCEEEEEEEEEECCCCHHHHHHHHHCCCCCCHHHHCCHHHHHHCCC DFTYRNVWNEIRTLHFEGQNAILLALKVLSNKIYRGVNRPDSIQVYCYSERYRQDLRQLV CHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHH MGLVNRCVSIQVGDIQQPCQTSRLRVAGKNWQLFFEDRGISLQEIGNESVCNDAESAVDF HHHHHHHEEEEECCCCCCHHHCCEEEECCCEEEEEECCCCCHHHCCCCHHCCCHHHCCCH DEVLQTPIEDGETNQESRRYPPEMDAFASEGFLQFFFEDNSDHSFNVYILDESNHLEIYR HHHHCCCCCCCCCCCHHCCCCCCHHHHHCCCEEEEEEECCCCCEEEEEEEECCCCEEEEE HCDGEKDEKVREINQLYQNAKQEGDKNPYNIVQHNFNYPQFYQLQNGKNGISIVPFKFRQ CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCEEEEECCCCCCCEEEEEHHHC MNK CCC >Mature Secondary Structure MECNLAQAKQWVSALDQRRFERALQGSGDAFQHVLAIAPLLLHLNHPQLPGYVIHAPSGI CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCHH ANFLASDYQKKWLTNEYGIHYADHKPSTLKSAVNFHEVFPPILGVYVMGSFGSISQTSSS HHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC DLDTWICVRDGLSPDEYTLLTQKAKRISEWAMQFNVEINFYLMDQQRFRNEHYADPLTIE CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEEEECHHHHCCCCCCCCEEEE NSGSAQYMLLLDEFYRSAVRLAGKPLLWLHLWVENEKDYEKEVARLITEGEIDPNDWVDF CCCCCEEEHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCC GGLGQFSANEYFGASLWHLYKGIDSPYKSVLKILLLEAYSKEYPNTCLIARTFKRDLLAG CCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCC NTNPDHHFDPYIAILAKVTQYLTALSEFKRLDFVHRCFYVKATEDFARYQANNWRIRYME CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHCCCCCEEHHHH ILAQEWGWSAETVKHLNKRPFWKIKAVKENHDNIMKFLMLSYRNLVEFARKHHIHSSVVP HHHHHHCCCHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC QDINILSRKLYTAFEELPGKVSLLNTQISHNLSEAHLTFVEVRGNKHFKDGWYLINQPIH CHHHHHHHHHHHHHHHCCCCEEEEHHHHHCCCCHHEEEEEEEECCCCCCCCCEEECCCHH HIMFSKERVIEYGESLNKLVSWAYFNHLLTEKTELSIFSKNVILSTLQSFVTNLRQSFPS HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCH TIAKQPKNSDLLNQCEIRSLFIAINLTTDPTSKVEEVLTGISSRDLFSFGSLEQSLVGSI HHHCCCCCCCHHHHHCEEEEEEEEEECCCCHHHHHHHHHCCCCCCHHHHCCHHHHHHCCC DFTYRNVWNEIRTLHFEGQNAILLALKVLSNKIYRGVNRPDSIQVYCYSERYRQDLRQLV CHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHH MGLVNRCVSIQVGDIQQPCQTSRLRVAGKNWQLFFEDRGISLQEIGNESVCNDAESAVDF HHHHHHHEEEEECCCCCCHHHCCEEEECCCEEEEEECCCCCHHHCCCCHHCCCHHHCCCH DEVLQTPIEDGETNQESRRYPPEMDAFASEGFLQFFFEDNSDHSFNVYILDESNHLEIYR HHHHCCCCCCCCCCCHHCCCCCCHHHHHCCCEEEEEEECCCCCEEEEEEEECCCCEEEEE HCDGEKDEKVREINQLYQNAKQEGDKNPYNIVQHNFNYPQFYQLQNGKNGISIVPFKFRQ CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCEEEEECCCCCCCEEEEEHHHC MNK CCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8226661; 7542800 [H]