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The map label for this gene is hemY [H]

Identifier: 148827894

GI number: 148827894

Start: 1275923

End: 1277209

Strand: Reverse

Name: hemY [H]

Synonym: CGSHiGG_06945

Alternate gene names: 148827894

Gene position: 1277209-1275923 (Counterclockwise)

Preceding gene: 148827895

Following gene: 148827889

Centisome position: 67.68

GC content: 36.67

Gene sequence:

>1287_bases
ATGTTTAGAGTGCTTTTTTTAATGCTGACATTGCTTGTAGGACTTGTAGCAGGGCCTTATATTTCTGGTCAGCAAGGTTA
TGTGCGCATTGAGACAGCAAATCGTATTATAGAAATGTCCATCACTACCTTAGTGATTTTTTTCATTATTTCTTTAGCAA
TAATTTATGCTTTTGAATGGGGCATCACTCGTTTCTTTCGTTTAAGTCGTAGCTCTTATCAATGGTTTTCTAATCGCAAA
CGTGTAAAAGCGCAAAAACAAACCCTTGAAGGCTTGGTAAAAATGGATGAAGGGGATTACGCTAAAGCAGAAAAATTAAT
TGGCAAAAATGCTAAACATTCTGCTGAACCTGTACTAAATCTCATCAAAGCAGCAGAAGCCGCTCAACAACGTGGCGACG
AATTTAGTGCAAATCGCTATTTAATTGAAGCAACAGAATTAGCCGGCTCTGATAATTTGCTCGTGGAAATTGCCCGTACT
CGCATTTTATTGCAACAAAACAAGTTACCTGCAGCACGCAGTTCTGTAGATAGCTTATTAGAAATGACTCGTCGCAATAA
AGAAGTATTAAAACTCGCGGTAGAAATTTATCTTCGCTCTAAAGCCTATCAAGCTCTAGATAAAATTTTAGACAATGTTG
CGAATAGCGGTTTATTCAATGATGAAGAATTCAAAGATCTTCGATCTAAAACCGAAAATGGTTTACTCGACGAGAAAATG
AACGAAGAAGGAATTGATGGCTTGCTAACTTGGTGGAATCAGCAACCTCGTCATCGCCGTAACAATATTGAACTTAAAAT
TAGCCTTATTCAACGTTTAATTGACTGTAATGATCATGAATCAGCTACTGAATTGACATTTGAAATACTGAAAAAACTCG
GTGACAATACAGCAATCAGTTTACCTCTTTGTACTCAAATTACACGTTTACAACCAGAAGATAACAGTAAACTTCTCAAG
CTAATAGAAAAACGTGCAAAACGTGTGGATGAAAAACAAAAATGCTGTATCAATCGTGCTTTGGGCTATTTATATGTTCG
TAACAATGAATTTCTTAAAGCAGCAGATGTATTCAAAAACGTCATCGCTTGCCCTGAACAATTAGAACAAAATGATTTGA
TGATGGCATCTTATGTATTTGAACAAGCGGGCGATAAAGCATTAGCTGAAAAAGTTCGCCAAGAGAGTTTGAAATCAGTG
ATGGCAATTCAGGATGTCATTCCAGAAAGTGCGGAAGAAAAAACAGAAGAAAATTCAACCGCACTTTTAGAAAGCAAATC
TGAGTAG

Upstream 100 bases:

>100_bases
CAAAAAGTGGAAATTGAAGCAGACAAGGCGATTGATACAATGCCTAAAGTAGAAGCTGTTAAACCAACACAATCTGAATC
ACAACAATAAGGATAAGTCT

Downstream 100 bases:

>100_bases
CTCAACTAAAAAGACAAAACGCACTTCAAGTGAAGTGCGTTTTTTTTTGTTTTTTTTGAATCTAAAACTATATATTTTTC
AGTTTATTAGAATATAACAC

Product: heme-biosynthesis protein HemY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MFRVLFLMLTLLVGLVAGPYISGQQGYVRIETANRIIEMSITTLVIFFIISLAIIYAFEWGITRFFRLSRSSYQWFSNRK
RVKAQKQTLEGLVKMDEGDYAKAEKLIGKNAKHSAEPVLNLIKAAEAAQQRGDEFSANRYLIEATELAGSDNLLVEIART
RILLQQNKLPAARSSVDSLLEMTRRNKEVLKLAVEIYLRSKAYQALDKILDNVANSGLFNDEEFKDLRSKTENGLLDEKM
NEEGIDGLLTWWNQQPRHRRNNIELKISLIQRLIDCNDHESATELTFEILKKLGDNTAISLPLCTQITRLQPEDNSKLLK
LIEKRAKRVDEKQKCCINRALGYLYVRNNEFLKAADVFKNVIACPEQLEQNDLMMASYVFEQAGDKALAEKVRQESLKSV
MAIQDVIPESAEEKTEENSTALLESKSE

Sequences:

>Translated_428_residues
MFRVLFLMLTLLVGLVAGPYISGQQGYVRIETANRIIEMSITTLVIFFIISLAIIYAFEWGITRFFRLSRSSYQWFSNRK
RVKAQKQTLEGLVKMDEGDYAKAEKLIGKNAKHSAEPVLNLIKAAEAAQQRGDEFSANRYLIEATELAGSDNLLVEIART
RILLQQNKLPAARSSVDSLLEMTRRNKEVLKLAVEIYLRSKAYQALDKILDNVANSGLFNDEEFKDLRSKTENGLLDEKM
NEEGIDGLLTWWNQQPRHRRNNIELKISLIQRLIDCNDHESATELTFEILKKLGDNTAISLPLCTQITRLQPEDNSKLLK
LIEKRAKRVDEKQKCCINRALGYLYVRNNEFLKAADVFKNVIACPEQLEQNDLMMASYVFEQAGDKALAEKVRQESLKSV
MAIQDVIPESAEEKTEENSTALLESKSE
>Mature_428_residues
MFRVLFLMLTLLVGLVAGPYISGQQGYVRIETANRIIEMSITTLVIFFIISLAIIYAFEWGITRFFRLSRSSYQWFSNRK
RVKAQKQTLEGLVKMDEGDYAKAEKLIGKNAKHSAEPVLNLIKAAEAAQQRGDEFSANRYLIEATELAGSDNLLVEIART
RILLQQNKLPAARSSVDSLLEMTRRNKEVLKLAVEIYLRSKAYQALDKILDNVANSGLFNDEEFKDLRSKTENGLLDEKM
NEEGIDGLLTWWNQQPRHRRNNIELKISLIQRLIDCNDHESATELTFEILKKLGDNTAISLPLCTQITRLQPEDNSKLLK
LIEKRAKRVDEKQKCCINRALGYLYVRNNEFLKAADVFKNVIACPEQLEQNDLMMASYVFEQAGDKALAEKVRQESLKSV
MAIQDVIPESAEEKTEENSTALLESKSE

Specific function: Involved in a late step of protoheme IX synthesis [H]

COG id: COG3071

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790234, Length=351, Percent_Identity=38.4615384615385, Blast_Score=261, Evalue=5e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010817
- InterPro:   IPR005254
- InterPro:   IPR011990 [H]

Pfam domain/function: PF07219 HemY_N [H]

EC number: NA

Molecular weight: Translated: 48821; Mature: 48821

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRVLFLMLTLLVGLVAGPYISGQQGYVRIETANRIIEMSITTLVIFFIISLAIIYAFEW
CHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GITRFFRLSRSSYQWFSNRKRVKAQKQTLEGLVKMDEGDYAKAEKLIGKNAKHSAEPVLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHH
LIKAAEAAQQRGDEFSANRYLIEATELAGSDNLLVEIARTRILLQQNKLPAARSSVDSLL
HHHHHHHHHHCCCCCCCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
EMTRRNKEVLKLAVEIYLRSKAYQALDKILDNVANSGLFNDEEFKDLRSKTENGLLDEKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHC
NEEGIDGLLTWWNQQPRHRRNNIELKISLIQRLIDCNDHESATELTFEILKKLGDNTAIS
CCCCCHHHHHHHCCCCHHCCCCCEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEE
LPLCTQITRLQPEDNSKLLKLIEKRAKRVDEKQKCCINRALGYLYVRNNEFLKAADVFKN
CHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEECCCHHHHHHHHHH
VIACPEQLEQNDLMMASYVFEQAGDKALAEKVRQESLKSVMAIQDVIPESAEEKTEENST
HHHCHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCH
ALLESKSE
HHHCCCCC
>Mature Secondary Structure
MFRVLFLMLTLLVGLVAGPYISGQQGYVRIETANRIIEMSITTLVIFFIISLAIIYAFEW
CHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GITRFFRLSRSSYQWFSNRKRVKAQKQTLEGLVKMDEGDYAKAEKLIGKNAKHSAEPVLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHH
LIKAAEAAQQRGDEFSANRYLIEATELAGSDNLLVEIARTRILLQQNKLPAARSSVDSLL
HHHHHHHHHHCCCCCCCCCEEEEEHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
EMTRRNKEVLKLAVEIYLRSKAYQALDKILDNVANSGLFNDEEFKDLRSKTENGLLDEKM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHC
NEEGIDGLLTWWNQQPRHRRNNIELKISLIQRLIDCNDHESATELTFEILKKLGDNTAIS
CCCCCHHHHHHHCCCCHHCCCCCEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEE
LPLCTQITRLQPEDNSKLLKLIEKRAKRVDEKQKCCINRALGYLYVRNNEFLKAADVFKN
CHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEECCCHHHHHHHHHH
VIACPEQLEQNDLMMASYVFEQAGDKALAEKVRQESLKSVMAIQDVIPESAEEKTEENST
HHHCHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCH
ALLESKSE
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]