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The map label for this gene is trkH [H]

Identifier: 148827891

GI number: 148827891

Start: 1267264

End: 1268727

Strand: Direct

Name: trkH [H]

Synonym: CGSHiGG_06930

Alternate gene names: 148827891

Gene position: 1267264-1268727 (Clockwise)

Preceding gene: 148827890

Following gene: 148827892

Centisome position: 67.15

GC content: 36.61

Gene sequence:

>1464_bases
GTGCGTATTTTATCGATTATCCGAATTATTGGTATTCTTGTGATGTGTTTTTCAGGTACGATGCTAGTTCCTGCATTTGT
TGCTCTGATTTATGGTGATGGGGGCGGCAAGGCATTTATGCAGGCTTTTATGTTGAGCTTGACAGCGGGCACATTACTTT
GGTGGCCATGCCATCACCATAAACAAGAATTACGATCTCGTGATGGTTTTTTGATTGTTGTGGCTTTTTGGTTAGTTTTA
GGAAGCTTGGCAACATTGCCTCTTTTATTGTTCGATTCACCACATTTAACTATTGCTTCAGCCGTATTTGAAGCATTTTC
TGGCTTAACTACTACTGGTGCAACGGTAATGACGGGGCTGGATAATTTACCTAAATCTATTTTGTTTTATCGTCAGTTTT
TACAATGGTTAGGTGGTATGGGGATTATCGTATTGGCTGTGGCGATAATTCCGCTGTTGGGAATTGGTGGGACACAATTA
TATCGAGCAGAATCTTCAGGCCCTCTTAAAGATCAAAAATCTTTGCCTAAAATTTCAGAAGTGGCGAAAGCGCTATGGAT
TATTTATGCTTCATTAACTGTTCTTTGTGCCATTGCATATTGGCTATCAGGAATGAATCTTTTTGATGCCATTGGGCATA
GTTTTTCAACAATTTCAAATGGCGGATTTTCAACGCACGATGCAAGTATTGGCTATTTTAATCAAGCTTCCATTTATTGG
GTTACAACAATTTTTATGCTGATTGGTGGTGTTAATTTTAGTTTACATATTTCCGCTTTTCTTGCACTAGGTAAAAGAAA
TATTTGGCGAAATTATTGGAAAGATCCCGAATTTCGTTTTTTTCTAACGATGCAAATTATTTTTATTGGTATTGTATCTC
TATCTTTATATGGTTATGGTTTAGTTTCAGATATAAACGAGGCAGTAACAAAAGGTGCATTACAATTAACATCAATGTCA
ATGACTGCTGGTTATACGATTTTTGATATTGATAATCTTCCGCCTTTTATTGGGCTTTTACTGGTAATTTCTGCGGTAAT
TGGTGGTTGTGGTGGTTCAACAACTGGGGGATTAAAAGCGATACGGACACTTATATTGTGGAAACAAATCGATCGAGAAC
TGCATAGTTTAATCCATCCAAATTTAGTACAACCAATTCGAATAGGTAAAAATCGTCTAGCACCAAGAATGATAGAAAGT
ATTTGGGCATTTTTCATTATTTTTATACTGGTTTATTGGGGGTGTGTTTTTGCTGTTATTCTTTGTGGAATGAATACTTT
TGATGCGATGGGAGCCGTATTCGCCACATTAACGAATGCAGGACCGGGACTTGGTTTTATTCACGAAAGTTTTATTGGTG
TTCCAGAAAGTGCTAAATTAGTCTTTAGTTTTGCTATGATCTGTGGACGTTTAGAAATGTTTTCATTAATCGTGCTGTTT
ATTCCAAGCTATTGGAAAAAATAA

Upstream 100 bases:

>100_bases
TAGGTATTAGTGAAAAAACAATAGAGGCGTTTTCTTCAGAATTAACGGAAAAGTCTTCAGGTAGATTAGTTATTCAACTT
TTAGAGATAGGCGAATAGTT

Downstream 100 bases:

>100_bases
TAATTGAAAAATTATTGCATTTTTAACCGCACTTTTTAATAAAATGTTTATATTTCCATCAAAAGATCATTTTTTTAAAT
ATTTTTACAAAAAAGTACTT

Product: Trk system potassium uptake protein TrkH

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MRILSIIRIIGILVMCFSGTMLVPAFVALIYGDGGGKAFMQAFMLSLTAGTLLWWPCHHHKQELRSRDGFLIVVAFWLVL
GSLATLPLLLFDSPHLTIASAVFEAFSGLTTTGATVMTGLDNLPKSILFYRQFLQWLGGMGIIVLAVAIIPLLGIGGTQL
YRAESSGPLKDQKSLPKISEVAKALWIIYASLTVLCAIAYWLSGMNLFDAIGHSFSTISNGGFSTHDASIGYFNQASIYW
VTTIFMLIGGVNFSLHISAFLALGKRNIWRNYWKDPEFRFFLTMQIIFIGIVSLSLYGYGLVSDINEAVTKGALQLTSMS
MTAGYTIFDIDNLPPFIGLLLVISAVIGGCGGSTTGGLKAIRTLILWKQIDRELHSLIHPNLVQPIRIGKNRLAPRMIES
IWAFFIIFILVYWGCVFAVILCGMNTFDAMGAVFATLTNAGPGLGFIHESFIGVPESAKLVFSFAMICGRLEMFSLIVLF
IPSYWKK

Sequences:

>Translated_487_residues
MRILSIIRIIGILVMCFSGTMLVPAFVALIYGDGGGKAFMQAFMLSLTAGTLLWWPCHHHKQELRSRDGFLIVVAFWLVL
GSLATLPLLLFDSPHLTIASAVFEAFSGLTTTGATVMTGLDNLPKSILFYRQFLQWLGGMGIIVLAVAIIPLLGIGGTQL
YRAESSGPLKDQKSLPKISEVAKALWIIYASLTVLCAIAYWLSGMNLFDAIGHSFSTISNGGFSTHDASIGYFNQASIYW
VTTIFMLIGGVNFSLHISAFLALGKRNIWRNYWKDPEFRFFLTMQIIFIGIVSLSLYGYGLVSDINEAVTKGALQLTSMS
MTAGYTIFDIDNLPPFIGLLLVISAVIGGCGGSTTGGLKAIRTLILWKQIDRELHSLIHPNLVQPIRIGKNRLAPRMIES
IWAFFIIFILVYWGCVFAVILCGMNTFDAMGAVFATLTNAGPGLGFIHESFIGVPESAKLVFSFAMICGRLEMFSLIVLF
IPSYWKK
>Mature_487_residues
MRILSIIRIIGILVMCFSGTMLVPAFVALIYGDGGGKAFMQAFMLSLTAGTLLWWPCHHHKQELRSRDGFLIVVAFWLVL
GSLATLPLLLFDSPHLTIASAVFEAFSGLTTTGATVMTGLDNLPKSILFYRQFLQWLGGMGIIVLAVAIIPLLGIGGTQL
YRAESSGPLKDQKSLPKISEVAKALWIIYASLTVLCAIAYWLSGMNLFDAIGHSFSTISNGGFSTHDASIGYFNQASIYW
VTTIFMLIGGVNFSLHISAFLALGKRNIWRNYWKDPEFRFFLTMQIIFIGIVSLSLYGYGLVSDINEAVTKGALQLTSMS
MTAGYTIFDIDNLPPFIGLLLVISAVIGGCGGSTTGGLKAIRTLILWKQIDRELHSLIHPNLVQPIRIGKNRLAPRMIES
IWAFFIIFILVYWGCVFAVILCGMNTFDAMGAVFATLTNAGPGLGFIHESFIGVPESAKLVFSFAMICGRLEMFSLIVLF
IPSYWKK

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=487, Percent_Identity=52.5667351129363, Blast_Score=474, Evalue=1e-135,
Organism=Escherichia coli, GI1787626, Length=484, Percent_Identity=36.7768595041322, Blast_Score=306, Evalue=2e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 53457; Mature: 53457

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILSIIRIIGILVMCFSGTMLVPAFVALIYGDGGGKAFMQAFMLSLTAGTLLWWPCHHH
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHEEECCHHH
KQELRSRDGFLIVVAFWLVLGSLATLPLLLFDSPHLTIASAVFEAFSGLTTTGATVMTGL
HHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
DNLPKSILFYRQFLQWLGGMGIIVLAVAIIPLLGIGGTQLYRAESSGPLKDQKSLPKISE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHCCCHHHH
VAKALWIIYASLTVLCAIAYWLSGMNLFDAIGHSFSTISNGGFSTHDASIGYFNQASIYW
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCHHHH
VTTIFMLIGGVNFSLHISAFLALGKRNIWRNYWKDPEFRFFLTMQIIFIGIVSLSLYGYG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCH
LVSDINEAVTKGALQLTSMSMTAGYTIFDIDNLPPFIGLLLVISAVIGGCGGSTTGGLKA
HHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
IRTLILWKQIDRELHSLIHPNLVQPIRIGKNRLAPRMIESIWAFFIIFILVYWGCVFAVI
HHHHHHHHHHHHHHHHHHCCCCCCHHHHCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCGMNTFDAMGAVFATLTNAGPGLGFIHESFIGVPESAKLVFSFAMICGRLEMFSLIVLF
HHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IPSYWKK
HHHHHCC
>Mature Secondary Structure
MRILSIIRIIGILVMCFSGTMLVPAFVALIYGDGGGKAFMQAFMLSLTAGTLLWWPCHHH
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHEEECCHHH
KQELRSRDGFLIVVAFWLVLGSLATLPLLLFDSPHLTIASAVFEAFSGLTTTGATVMTGL
HHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
DNLPKSILFYRQFLQWLGGMGIIVLAVAIIPLLGIGGTQLYRAESSGPLKDQKSLPKISE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHCCCHHHH
VAKALWIIYASLTVLCAIAYWLSGMNLFDAIGHSFSTISNGGFSTHDASIGYFNQASIYW
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCHHHH
VTTIFMLIGGVNFSLHISAFLALGKRNIWRNYWKDPEFRFFLTMQIIFIGIVSLSLYGYG
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCH
LVSDINEAVTKGALQLTSMSMTAGYTIFDIDNLPPFIGLLLVISAVIGGCGGSTTGGLKA
HHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCHHHHH
IRTLILWKQIDRELHSLIHPNLVQPIRIGKNRLAPRMIESIWAFFIIFILVYWGCVFAVI
HHHHHHHHHHHHHHHHHHCCCCCCHHHHCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCGMNTFDAMGAVFATLTNAGPGLGFIHESFIGVPESAKLVFSFAMICGRLEMFSLIVLF
HHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IPSYWKK
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]