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The map label for this gene is tig [H]

Identifier: 148827881

GI number: 148827881

Start: 1259565

End: 1260863

Strand: Direct

Name: tig [H]

Synonym: CGSHiGG_06880

Alternate gene names: 148827881

Gene position: 1259565-1260863 (Clockwise)

Preceding gene: 148827879

Following gene: 148827882

Centisome position: 66.74

GC content: 36.64

Gene sequence:

>1299_bases
ATGTCATTAAATATTGAAACAACTCAAGGTTTAGAACGTCGCGTAGCGATCACCGTTCCAACTGAAATTGTCTCTAAAGC
CATTCACGAAGAATTTAAACGTGCTGCAAAAAATGTGCGCGTAGATGGTTTCCGTAAAGGTCATGTTCCTGCCCATATCA
TTGAACAACGTTTTGGGGCGTCAATTCGTCAAGATGTATTAAACGATTTATTACCACGTCATTTTTTTGATGCTGTTATT
GCAGAAAAAATTAATATTGCAGGTCGTCCAACTTTTGCGATTGAAACTTTTGAAGAAGGTAAAGATCTTGTATTTACTGC
AACTTTCGAGGTTTATCCAGAAGTTAAATTACAAGGTTTAGAAAATATCAAAGTTGAAAAACCAACTGTTGAAATCACGG
AAGCTGATATTGATAAAATGATCGATGTGTTACGTAAACAACAAGCTACTTGGGCTGAAAGTCAAGATATTGCAAAAGCA
GATGATCGCGTTACTATTGACTTTGTTGGCTCTGTAGATGGCGAAGAATTTGAAGGTGGTAAAGCTACTGACTTCGTATT
ATTTATGGGTCAAGGTCGTATGATCCCTGGTTTTGAAGAAGGAATTGTCGGTCATAAAGCAGGTGAGCAATTTGATATTG
ATGTGACTTTCCCAGCGGAATACCACGCAGAAAACTTGAAAGGTAAAGCGGCAAAATTTGCGATTACTTTGAAAAAAGTC
GAAAATATGGTATTGCCTGAATTAACAGATGAGTTTGTCGCTAAATTTGGCCCTAATACTAAGTCTGTTGCTGATTTGCG
TGCAGAAATCCGTAAAAATATGGAACGTGAATTGAAAAATGCGTTAGTTTCTCGTGTTAAACAACAAGTAATCAATGGTT
TAATTGAACAAAATCCGATTGATGTACCCGCTTCTGTAGTAGAAGAAGAAATTAATGTATTACGCAATCAAGCGGCTCAA
CGTTTTGGCGGTAATACACAACAAGCTGCACAGTTACCACGTGAATTATTTGAAGCTGAAGCAACTCGTCGTGTTCAAGT
AGGTTTATTATTCTCTGAAGTAATTAAATCTAATGAATTAAAAGCTGATAAAGAACGTGCTAAAGCAATGATTGCTGATA
TTGCGTCAGCTTACGAGCAGCCAGCAGAAGTGGTGGAATATTACAGCAAAAACAAAGAGTTAATGAACAATATTCGTAAT
GTCGTATTAGAAGAACAAGCTGTTGATGCAGTACTTGCAAAAGCACAAGTAACAGAAAAAGTTTCTTCATTCGATGAAAT
TATGAATCCACAAGCATAA

Upstream 100 bases:

>100_bases
TCGACTGCGTAGATTTCTTTAGTTATAATTGAGCGTCTTTTTATTTAACAAACGTGTTCGGTGTGGATTTTGACCGAGTG
CAAATTAATTGAGGTAACAA

Downstream 100 bases:

>100_bases
TAAGTAATATCATTATGATTGAATAAAAGTGCGGTCGCTCTTTCTAATAAAAGCGATCGCATTTTTATTTGTGGGTTATT
TACGATAAAATAATTAGCAG

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MSLNIETTQGLERRVAITVPTEIVSKAIHEEFKRAAKNVRVDGFRKGHVPAHIIEQRFGASIRQDVLNDLLPRHFFDAVI
AEKINIAGRPTFAIETFEEGKDLVFTATFEVYPEVKLQGLENIKVEKPTVEITEADIDKMIDVLRKQQATWAESQDIAKA
DDRVTIDFVGSVDGEEFEGGKATDFVLFMGQGRMIPGFEEGIVGHKAGEQFDIDVTFPAEYHAENLKGKAAKFAITLKKV
ENMVLPELTDEFVAKFGPNTKSVADLRAEIRKNMERELKNALVSRVKQQVINGLIEQNPIDVPASVVEEEINVLRNQAAQ
RFGGNTQQAAQLPRELFEAEATRRVQVGLLFSEVIKSNELKADKERAKAMIADIASAYEQPAEVVEYYSKNKELMNNIRN
VVLEEQAVDAVLAKAQVTEKVSSFDEIMNPQA

Sequences:

>Translated_432_residues
MSLNIETTQGLERRVAITVPTEIVSKAIHEEFKRAAKNVRVDGFRKGHVPAHIIEQRFGASIRQDVLNDLLPRHFFDAVI
AEKINIAGRPTFAIETFEEGKDLVFTATFEVYPEVKLQGLENIKVEKPTVEITEADIDKMIDVLRKQQATWAESQDIAKA
DDRVTIDFVGSVDGEEFEGGKATDFVLFMGQGRMIPGFEEGIVGHKAGEQFDIDVTFPAEYHAENLKGKAAKFAITLKKV
ENMVLPELTDEFVAKFGPNTKSVADLRAEIRKNMERELKNALVSRVKQQVINGLIEQNPIDVPASVVEEEINVLRNQAAQ
RFGGNTQQAAQLPRELFEAEATRRVQVGLLFSEVIKSNELKADKERAKAMIADIASAYEQPAEVVEYYSKNKELMNNIRN
VVLEEQAVDAVLAKAQVTEKVSSFDEIMNPQA
>Mature_431_residues
SLNIETTQGLERRVAITVPTEIVSKAIHEEFKRAAKNVRVDGFRKGHVPAHIIEQRFGASIRQDVLNDLLPRHFFDAVIA
EKINIAGRPTFAIETFEEGKDLVFTATFEVYPEVKLQGLENIKVEKPTVEITEADIDKMIDVLRKQQATWAESQDIAKAD
DRVTIDFVGSVDGEEFEGGKATDFVLFMGQGRMIPGFEEGIVGHKAGEQFDIDVTFPAEYHAENLKGKAAKFAITLKKVE
NMVLPELTDEFVAKFGPNTKSVADLRAEIRKNMERELKNALVSRVKQQVINGLIEQNPIDVPASVVEEEINVLRNQAAQR
FGGNTQQAAQLPRELFEAEATRRVQVGLLFSEVIKSNELKADKERAKAMIADIASAYEQPAEVVEYYSKNKELMNNIRNV
VLEEQAVDAVLAKAQVTEKVSSFDEIMNPQA

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=432, Percent_Identity=65.9722222222222, Blast_Score=590, Evalue=1e-170,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 48299; Mature: 48167

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNIETTQGLERRVAITVPTEIVSKAIHEEFKRAAKNVRVDGFRKGHVPAHIIEQRFGA
CCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCC
SIRQDVLNDLLPRHFFDAVIAEKINIAGRPTFAIETFEEGKDLVFTATFEVYPEVKLQGL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEEECCCCHHHCCC
ENIKVEKPTVEITEADIDKMIDVLRKQQATWAESQDIAKADDRVTIDFVGSVDGEEFEGG
CCCEECCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCEEEEEEECCCCCCCCCC
KATDFVLFMGQGRMIPGFEEGIVGHKAGEQFDIDVTFPAEYHAENLKGKAAKFAITLKKV
CCEEEEEEECCCCCCCCHHHCCCCCCCCCEEEEEEECCHHHHHHCCCCCHHHHHHHHHHH
ENMVLPELTDEFVAKFGPNTKSVADLRAEIRKNMERELKNALVSRVKQQVINGLIEQNPI
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DVPASVVEEEINVLRNQAAQRFGGNTQQAAQLPRELFEAEATRRVQVGLLFSEVIKSNEL
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KADKERAKAMIADIASAYEQPAEVVEYYSKNKELMNNIRNVVLEEQAVDAVLAKAQVTEK
CHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSSFDEIMNPQA
HHHHHHHCCCCC
>Mature Secondary Structure 
SLNIETTQGLERRVAITVPTEIVSKAIHEEFKRAAKNVRVDGFRKGHVPAHIIEQRFGA
CCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCC
SIRQDVLNDLLPRHFFDAVIAEKINIAGRPTFAIETFEEGKDLVFTATFEVYPEVKLQGL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEEEEEECCCCHHHCCC
ENIKVEKPTVEITEADIDKMIDVLRKQQATWAESQDIAKADDRVTIDFVGSVDGEEFEGG
CCCEECCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCEEEEEEECCCCCCCCCC
KATDFVLFMGQGRMIPGFEEGIVGHKAGEQFDIDVTFPAEYHAENLKGKAAKFAITLKKV
CCEEEEEEECCCCCCCCHHHCCCCCCCCCEEEEEEECCHHHHHHCCCCCHHHHHHHHHHH
ENMVLPELTDEFVAKFGPNTKSVADLRAEIRKNMERELKNALVSRVKQQVINGLIEQNPI
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DVPASVVEEEINVLRNQAAQRFGGNTQQAAQLPRELFEAEATRRVQVGLLFSEVIKSNEL
CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KADKERAKAMIADIASAYEQPAEVVEYYSKNKELMNNIRNVVLEEQAVDAVLAKAQVTEK
CHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSSFDEIMNPQA
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA