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The map label for this gene is ppx [H]

Identifier: 148827868

GI number: 148827868

Start: 1234025

End: 1235002

Strand: Reverse

Name: ppx [H]

Synonym: CGSHiGG_06770

Alternate gene names: 148827868

Gene position: 1235002-1234025 (Counterclockwise)

Preceding gene: 148827869

Following gene: 148827864

Centisome position: 65.44

GC content: 42.02

Gene sequence:

>978_bases
ATGAATGACGCTATTTTAGAACCCAAACATCGTGGCAATGTATGTGAAATTGCCGCAATTGATCTTGGCTCAAACAGCTT
TCATATGATTGTTGCGCGTATTGTAAACGGCTCAATCCAAGTGCTTTCTCGCTTAAAACAAAAAGTTAAACTCGCAGAAG
GCTTAGATGAAAATGCGGTGCTTAATCAAGAGGCCATCACACGTGGCGTGAATTGCTTAGCCTTATTTGCCGAACGTTTA
CAAGGTTTTCCTATGGAAAACGTCAATGTAGTTGGCACTTATACGTTACGAAGAGCGGTGAATAATGACGAATTTTTACG
TCAAGCAGCCAAAGTTTTCCCCTATCCCATTAATATTATTAGTGGGCAAACTGAAGCTAAAACCATCTACGCTGGCGTAT
GCCATACTCAGCCAGAAAAAGGCAGAAAGCTTGTTATAGATATTGGTGGTGGTTCGACAGAAATGATTATCGGCGATGAT
TTCACGCCGCTTATAGCTGAAAGCCGACATATGGGATGCGTGAGTTTTGCGACTCAATTTTTTACCGATGGCATCATTTC
CCCAGAAAATTTTCAACGCGCGCACCAAAGTGCGGTCAATAAAATCGAAGATTTAGGTCTTGAATATCGCAAATTAGGTT
GGCAATCTGTGCTCGGCTCATCGGGGACAATTAAAACTGTTGCGCAAGTCATTGCGACTAATCTCGATCCAAATGGAACC
ATTACAGCCGAGCGATTAAATGCTCTAATTGAACAAACACTACAAGCCAAGCATTTTACCGAGCTAAATATTAACGGTTT
AAACCAAGACCGCGTGGATGTTTTTGTACCCGGTTTAGCGATTTTAAGTGCAGTGTTTGACGTTTTTCATATTCAACAAA
TGCGCTATTCTGACGGTGCATTGCGCGAAGGCGTCATTTATAGCCTAGAAAAAACTTCCAAGTTGCAGATATTCGAGCGT
GCACCGCTTGAGGGTTAA

Upstream 100 bases:

>100_bases
ACATTACGTTATCGCCTAATGCCACAGCTTTATTTTCAATCCGTTTCTAGCACAAACCAAGTGTTTGATTTACTTTATAA
ATTTGAATTTTAGGAATGTT

Downstream 100 bases:

>100_bases
GTGAGCAATTCAATATTGACCAAGCTCATCGCGTTGTGGATAGTGCTAATTTACTCAGTGCGCAATATTTATGGGAGAAA
AATTTAGGGCAAGCTAAATA

Product: exopolyphosphatase

Products: NA

Alternate protein names: Metaphosphatase [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MNDAILEPKHRGNVCEIAAIDLGSNSFHMIVARIVNGSIQVLSRLKQKVKLAEGLDENAVLNQEAITRGVNCLALFAERL
QGFPMENVNVVGTYTLRRAVNNDEFLRQAAKVFPYPINIISGQTEAKTIYAGVCHTQPEKGRKLVIDIGGGSTEMIIGDD
FTPLIAESRHMGCVSFATQFFTDGIISPENFQRAHQSAVNKIEDLGLEYRKLGWQSVLGSSGTIKTVAQVIATNLDPNGT
ITAERLNALIEQTLQAKHFTELNINGLNQDRVDVFVPGLAILSAVFDVFHIQQMRYSDGALREGVIYSLEKTSKLQIFER
APLEG

Sequences:

>Translated_325_residues
MNDAILEPKHRGNVCEIAAIDLGSNSFHMIVARIVNGSIQVLSRLKQKVKLAEGLDENAVLNQEAITRGVNCLALFAERL
QGFPMENVNVVGTYTLRRAVNNDEFLRQAAKVFPYPINIISGQTEAKTIYAGVCHTQPEKGRKLVIDIGGGSTEMIIGDD
FTPLIAESRHMGCVSFATQFFTDGIISPENFQRAHQSAVNKIEDLGLEYRKLGWQSVLGSSGTIKTVAQVIATNLDPNGT
ITAERLNALIEQTLQAKHFTELNINGLNQDRVDVFVPGLAILSAVFDVFHIQQMRYSDGALREGVIYSLEKTSKLQIFER
APLEG
>Mature_325_residues
MNDAILEPKHRGNVCEIAAIDLGSNSFHMIVARIVNGSIQVLSRLKQKVKLAEGLDENAVLNQEAITRGVNCLALFAERL
QGFPMENVNVVGTYTLRRAVNNDEFLRQAAKVFPYPINIISGQTEAKTIYAGVCHTQPEKGRKLVIDIGGGSTEMIIGDD
FTPLIAESRHMGCVSFATQFFTDGIISPENFQRAHQSAVNKIEDLGLEYRKLGWQSVLGSSGTIKTVAQVIATNLDPNGT
ITAERLNALIEQTLQAKHFTELNINGLNQDRVDVFVPGLAILSAVFDVFHIQQMRYSDGALREGVIYSLEKTSKLQIFER
APLEG

Specific function: Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate [H]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=295, Percent_Identity=56.271186440678, Blast_Score=360, Evalue=1e-101,
Organism=Escherichia coli, GI48994966, Length=293, Percent_Identity=43.6860068259386, Blast_Score=240, Evalue=7e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022371
- InterPro:   IPR003695 [H]

Pfam domain/function: PF02541 Ppx-GppA [H]

EC number: =3.6.1.11 [H]

Molecular weight: Translated: 35756; Mature: 35756

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDAILEPKHRGNVCEIAAIDLGSNSFHMIVARIVNGSIQVLSRLKQKVKLAEGLDENAV
CCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCE
LNQEAITRGVNCLALFAERLQGFPMENVNVVGTYTLRRAVNNDEFLRQAAKVFPYPINII
ECHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHCCCHHHHHHHHHHCCCCEEEE
SGQTEAKTIYAGVCHTQPEKGRKLVIDIGGGSTEMIIGDDFTPLIAESRHMGCVSFATQF
CCCCCCCEEEEEECCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHCCCCCHHHHHHHHH
FTDGIISPENFQRAHQSAVNKIEDLGLEYRKLGWQSVLGSSGTIKTVAQVIATNLDPNGT
HHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCC
ITAERLNALIEQTLQAKHFTELNINGLNQDRVDVFVPGLAILSAVFDVFHIQQMRYSDGA
EEHHHHHHHHHHHHHHHHCCEEECCCCCCCCHHEEECHHHHHHHHHHHHHHHHHHCCCCC
LREGVIYSLEKTSKLQIFERAPLEG
HHCCEEEEECCCCCEEHEECCCCCC
>Mature Secondary Structure
MNDAILEPKHRGNVCEIAAIDLGSNSFHMIVARIVNGSIQVLSRLKQKVKLAEGLDENAV
CCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCE
LNQEAITRGVNCLALFAERLQGFPMENVNVVGTYTLRRAVNNDEFLRQAAKVFPYPINII
ECHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHCCCHHHHHHHHHHCCCCEEEE
SGQTEAKTIYAGVCHTQPEKGRKLVIDIGGGSTEMIIGDDFTPLIAESRHMGCVSFATQF
CCCCCCCEEEEEECCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHCCCCCHHHHHHHHH
FTDGIISPENFQRAHQSAVNKIEDLGLEYRKLGWQSVLGSSGTIKTVAQVIATNLDPNGT
HHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCC
ITAERLNALIEQTLQAKHFTELNINGLNQDRVDVFVPGLAILSAVFDVFHIQQMRYSDGA
EEHHHHHHHHHHHHHHHHCCEEECCCCCCCCHHEEECHHHHHHHHHHHHHHHHHHCCCCC
LREGVIYSLEKTSKLQIFERAPLEG
HHCCEEEEECCCCCEEHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]