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The map label for this gene is glpA [H]

Identifier: 148827859

GI number: 148827859

Start: 1224211

End: 1225902

Strand: Reverse

Name: glpA [H]

Synonym: CGSHiGG_06725

Alternate gene names: 148827859

Gene position: 1225902-1224211 (Counterclockwise)

Preceding gene: 148827864

Following gene: 148827858

Centisome position: 64.96

GC content: 43.85

Gene sequence:

>1692_bases
ATGGGATTATCGCCTAGTATCTATAAAGATGTTGGAGATCTTTCGTCACTTAGCACTGATGTGATCATTATCGGTGGTGG
CGCAACAGGAGCAGGTATTGCGCGCGATTGCGCACTTCGTGGCATTGATTGTATTTTATTGGAACGTCGAGATATTGCGA
CAGGAGCCACAGGACGTAACCACGGATTATTACACAGTGGTGCGCGTTACGCCGTGAACGACCAAGAATCTGCTGAAGAA
TGTATTAAAGAAAACCGCATTTTGCGCAAAATTGCACGTCATTGCGTAGATGAAACGGAAGGCTTATTTATCACTTTGCC
TGAAGATTCGCTCGACTATCAAAAAACCTTCCTTGAGAGCTGTGCAAAATCTGGAATTGATGCGCAAGCCATTGATCCTG
AACTAGCTAAAATTATGGAACCTTCAGTAAACCCTGATTTAGTGGGCGCTGTTGTTGTGCCAGATGGTTCTATTGACCCA
TTCCGTTTAACCGCCTCTAATATGATGGACGCCACAGAAAACGGCGCAAAAATGTTCACTTATTGCGAAGTAAAAAATTT
GATTCGTGAAGGTGGAAAAGTGATTGGCGTAAATGTGTACGATCACAAAAATCGCAGAGAACGCCAATTTTTTGCACCGC
TTGTTGTAAATGCTAGTGGTATTTGGGGACAAGGGATTGCGGAATATGCCGATCTCAAAATTAAAATGTTCCCTGCAAAA
GGCGCATTGCTCGTAATGGGCCATCGCATTAATAAACTTGTCATTAACCGCTGCCGTAAACCTGCTGATGCGGATATTCT
CGTACCTGGCGATACAATTTGTGTTATAGGAACAACATCTAGCCGCATTCCTTATGATCAAATTGATAATATGGAAGTAA
CGCCAGAGGAAGTGGATATTCTTTTCCGTGAGGGAGAAAAACTTGCGCCTAGTTTGCGTCATACACGTGTATTACGTGCT
TACGCTGGGGTGCGACCATTAGTTGCGAGTGATGATGATCCATCAGGTCGTAATGTGAGCCGTGGTATTGTGTTACTTGA
CCACGCAGAACGTGATGGGTTAGATGGCTTTATTACAATCACTGGCGGTAAGTTAATGACTTATCGTTTAATGGCTGAAT
GGGCGACCGACCTTGTTTGTAAAAAACTCAATAAAACAGCTCGTTGTGTAACTGCGGAGCAACCTTTGCCTGGCTCTACT
GAAAGCCGTCAAGAGACCAATCAAAAAGTCATTTCATTACCAAGTACTATTCGTTATTCTGCTGTGTATCGTCATGGTTC
ACGTGCTACTCGTTTGCTTGAAAAAGAACGTTTAGATCGTTCAATGGTTTGCGAATGCGAAGCGGTGACAGCAGGGGAAG
TTCGTTACGCTGTTGATGAACTGGATGTAAATAATCTCGTTGATTTACGTCGTCGTTCCCGAGTTGGAATGGGAACTTGT
CAAGCTGAACTCTGTGCTTGTCGTGCTGCAGGACTAATGAATCGTTTTGAAGTGGCAACACCACGTCAATCAACTACTCA
ACTTTCTGCTTTTATGGAAGAACGCTGGCGCGGTATTGAGCCGATTGCTTGGGGGGAAGCTATTCGCGAAGCCGAATTTA
CATCTTGGATGTATGGTAGCGTATTAGGTTTAAATGATGTGAAACCGCTTGATGAACAAGCACAACAAGGGACGGATAGC
AATGAATTTTGA

Upstream 100 bases:

>100_bases
TCTTTTACGCTCAAAATGTTGTTAATTTTGCCGCACTTCTCTACAATGATTACACTTTTTATATTATTTTTTATTACATT
TTGGGAATCGGGGGTAAACA

Downstream 100 bases:

>100_bases
TGTAGCCATTATTGGCGGTGGTTTGGCAGGTTTAACCTGTGGCATCGCCATTCAACAACGCGGCAAACGTTGCGTGATTA
TCAACAACGGTCAAGCAGCC

Product: sn-glycerol-3-phosphate dehydrogenase subunit A

Products: NA

Alternate protein names: G-3-P dehydrogenase [H]

Number of amino acids: Translated: 563; Mature: 562

Protein sequence:

>563_residues
MGLSPSIYKDVGDLSSLSTDVIIIGGGATGAGIARDCALRGIDCILLERRDIATGATGRNHGLLHSGARYAVNDQESAEE
CIKENRILRKIARHCVDETEGLFITLPEDSLDYQKTFLESCAKSGIDAQAIDPELAKIMEPSVNPDLVGAVVVPDGSIDP
FRLTASNMMDATENGAKMFTYCEVKNLIREGGKVIGVNVYDHKNRRERQFFAPLVVNASGIWGQGIAEYADLKIKMFPAK
GALLVMGHRINKLVINRCRKPADADILVPGDTICVIGTTSSRIPYDQIDNMEVTPEEVDILFREGEKLAPSLRHTRVLRA
YAGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITITGGKLMTYRLMAEWATDLVCKKLNKTARCVTAEQPLPGST
ESRQETNQKVISLPSTIRYSAVYRHGSRATRLLEKERLDRSMVCECEAVTAGEVRYAVDELDVNNLVDLRRRSRVGMGTC
QAELCACRAAGLMNRFEVATPRQSTTQLSAFMEERWRGIEPIAWGEAIREAEFTSWMYGSVLGLNDVKPLDEQAQQGTDS
NEF

Sequences:

>Translated_563_residues
MGLSPSIYKDVGDLSSLSTDVIIIGGGATGAGIARDCALRGIDCILLERRDIATGATGRNHGLLHSGARYAVNDQESAEE
CIKENRILRKIARHCVDETEGLFITLPEDSLDYQKTFLESCAKSGIDAQAIDPELAKIMEPSVNPDLVGAVVVPDGSIDP
FRLTASNMMDATENGAKMFTYCEVKNLIREGGKVIGVNVYDHKNRRERQFFAPLVVNASGIWGQGIAEYADLKIKMFPAK
GALLVMGHRINKLVINRCRKPADADILVPGDTICVIGTTSSRIPYDQIDNMEVTPEEVDILFREGEKLAPSLRHTRVLRA
YAGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITITGGKLMTYRLMAEWATDLVCKKLNKTARCVTAEQPLPGST
ESRQETNQKVISLPSTIRYSAVYRHGSRATRLLEKERLDRSMVCECEAVTAGEVRYAVDELDVNNLVDLRRRSRVGMGTC
QAELCACRAAGLMNRFEVATPRQSTTQLSAFMEERWRGIEPIAWGEAIREAEFTSWMYGSVLGLNDVKPLDEQAQQGTDS
NEF
>Mature_562_residues
GLSPSIYKDVGDLSSLSTDVIIIGGGATGAGIARDCALRGIDCILLERRDIATGATGRNHGLLHSGARYAVNDQESAEEC
IKENRILRKIARHCVDETEGLFITLPEDSLDYQKTFLESCAKSGIDAQAIDPELAKIMEPSVNPDLVGAVVVPDGSIDPF
RLTASNMMDATENGAKMFTYCEVKNLIREGGKVIGVNVYDHKNRRERQFFAPLVVNASGIWGQGIAEYADLKIKMFPAKG
ALLVMGHRINKLVINRCRKPADADILVPGDTICVIGTTSSRIPYDQIDNMEVTPEEVDILFREGEKLAPSLRHTRVLRAY
AGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITITGGKLMTYRLMAEWATDLVCKKLNKTARCVTAEQPLPGSTE
SRQETNQKVISLPSTIRYSAVYRHGSRATRLLEKERLDRSMVCECEAVTAGEVRYAVDELDVNNLVDLRRRSRVGMGTCQ
AELCACRAAGLMNRFEVATPRQSTTQLSAFMEERWRGIEPIAWGEAIREAEFTSWMYGSVLGLNDVKPLDEQAQQGTDSN
EF

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Fumarate Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=Loosely bound to the cytoplasmic membrane often occurring in vesicles associated with fumarate reductase (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=524, Percent_Identity=26.3358778625954, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI285002231, Length=524, Percent_Identity=26.3358778625954, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI197927446, Length=287, Percent_Identity=25.0871080139373, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI21361378, Length=287, Percent_Identity=25.0871080139373, Blast_Score=76, Evalue=1e-13,
Organism=Escherichia coli, GI1788574, Length=529, Percent_Identity=70.6994328922495, Blast_Score=750, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17509253, Length=412, Percent_Identity=28.6407766990291, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115534726, Length=411, Percent_Identity=26.2773722627737, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI161077125, Length=409, Percent_Identity=27.8728606356968, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24653942, Length=409, Percent_Identity=27.8728606356968, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24653944, Length=409, Percent_Identity=27.8728606356968, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI20130025, Length=409, Percent_Identity=27.8728606356968, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI20130091, Length=243, Percent_Identity=30.8641975308642, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24586295, Length=378, Percent_Identity=23.8095238095238, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19921278, Length=409, Percent_Identity=25.9168704156479, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007419
- InterPro:   IPR006076
- InterPro:   IPR017752
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO; PF04324 Fer2_BFD [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 61964; Mature: 61833

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLSPSIYKDVGDLSSLSTDVIIIGGGATGAGIARDCALRGIDCILLERRDIATGATGRN
CCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCC
HGLLHSGARYAVNDQESAEECIKENRILRKIARHCVDETEGLFITLPEDSLDYQKTFLES
CCCEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHH
CAKSGIDAQAIDPELAKIMEPSVNPDLVGAVVVPDGSIDPFRLTASNMMDATENGAKMFT
HHHCCCCCCCCCHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEHHHHHHCCCCCCEEEE
YCEVKNLIREGGKVIGVNVYDHKNRRERQFFAPLVVNASGIWGQGIAEYADLKIKMFPAK
HHHHHHHHHCCCEEEEEEEECCCCCHHHHHCCCEEEECCCCCCCCHHHHHCEEEEEECCC
GALLVMGHRINKLVINRCRKPADADILVPGDTICVIGTTSSRIPYDQIDNMEVTPEEVDI
CEEEEECCHHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCCCHHHCCCCCCCHHHHHH
LFREGEKLAPSLRHTRVLRAYAGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITI
HHHCCCHHCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCCEEEEE
TGGKLMTYRLMAEWATDLVCKKLNKTARCVTAEQPLPGSTESRQETNQKVISLPSTIRYS
ECCCEEHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCHHHHHHHHEEECCCHHHHH
AVYRHGSRATRLLEKERLDRSMVCECEAVTAGEVRYAVDELDVNNLVDLRRRSRVGMGTC
HHHHCCHHHHHHHHHHHCCHHHEEEECCCCCCCEEEHHHHCCHHHHHHHHHHHCCCCCHH
QAELCACRAAGLMNRFEVATPRQSTTQLSAFMEERWRGIEPIAWGEAIREAEFTSWMYGS
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHC
VLGLNDVKPLDEQAQQGTDSNEF
EECCCCCCCCHHHHHCCCCCCCC
>Mature Secondary Structure 
GLSPSIYKDVGDLSSLSTDVIIIGGGATGAGIARDCALRGIDCILLERRDIATGATGRN
CCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCC
HGLLHSGARYAVNDQESAEECIKENRILRKIARHCVDETEGLFITLPEDSLDYQKTFLES
CCCEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHH
CAKSGIDAQAIDPELAKIMEPSVNPDLVGAVVVPDGSIDPFRLTASNMMDATENGAKMFT
HHHCCCCCCCCCHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEHHHHHHCCCCCCEEEE
YCEVKNLIREGGKVIGVNVYDHKNRRERQFFAPLVVNASGIWGQGIAEYADLKIKMFPAK
HHHHHHHHHCCCEEEEEEEECCCCCHHHHHCCCEEEECCCCCCCCHHHHHCEEEEEECCC
GALLVMGHRINKLVINRCRKPADADILVPGDTICVIGTTSSRIPYDQIDNMEVTPEEVDI
CEEEEECCHHHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCCCHHHCCCCCCCHHHHHH
LFREGEKLAPSLRHTRVLRAYAGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITI
HHHCCCHHCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEECCCCCCCCEEEEE
TGGKLMTYRLMAEWATDLVCKKLNKTARCVTAEQPLPGSTESRQETNQKVISLPSTIRYS
ECCCEEHHHHHHHHHHHHHHHHHCCHHEEEECCCCCCCCCCHHHHHHHHEEECCCHHHHH
AVYRHGSRATRLLEKERLDRSMVCECEAVTAGEVRYAVDELDVNNLVDLRRRSRVGMGTC
HHHHCCHHHHHHHHHHHCCHHHEEEECCCCCCCEEEHHHHCCHHHHHHHHHHHCCCCCHH
QAELCACRAAGLMNRFEVATPRQSTTQLSAFMEERWRGIEPIAWGEAIREAEFTSWMYGS
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHC
VLGLNDVKPLDEQAQQGTDSNEF
EECCCCCCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]