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The map label for this gene is ilvY [H]

Identifier: 148827855

GI number: 148827855

Start: 1218512

End: 1219390

Strand: Reverse

Name: ilvY [H]

Synonym: CGSHiGG_06695

Alternate gene names: 148827855

Gene position: 1219390-1218512 (Counterclockwise)

Preceding gene: 148827856

Following gene: 148827854

Centisome position: 64.61

GC content: 40.61

Gene sequence:

>879_bases
ATGGAATTTACCGACCTACAAATATTCATTCACCTTAGTGATACAAAAAACTTCACCAAAACCGCCACCCAAAACCACAT
GTCTCCCTCTACCCTTTCCCGTCAAATTCAACGATTGGAAGACGAGTTAGGGAAGACACTTTTTATCCGTGATAATCGCC
AAGTCAAACTTACTGAATATGGCGAGAAATTTTTGCAATTTGCTAAAACAGAATGGCAAAACTGGCAACAATTTAAACAA
CAACTGAAAGATGAATCCGATGAACTTTGCGGTGAAATTAAACTTTTTTGTTCTGTAACCGCATCCTATAGCCATCTTCC
GAACGTACTTAAAGAATTTCGCCAGCGTTATCCTAAAGTGGAAATTCAACTGACTACAGGCGATCCAGCGTTAGCACTAG
AATTAATTCAAGCGCAACAAGTCGATCTCGCGCTTGCGGGGAAACCAAATAATCTGCCCTCTAGTGTAGTGTTTCATAAA
ATAGATGATATTAGTTTGTCCCTAATTGCCCCGCGAGTGGCTTGTTTGGCGACACAATTATTGCAAGAAAAACCTATTGA
TTGGCAGCAAATGCCTTTTATTTTTCCCGTTGAAGGTCACGCACGGCAGCGAATTGAACAATGGTTAAGGGAGAAACAAA
TTAAACACCCGAAAATTTATGCTACTGTTGCGGGACACGAAGGAATTGTGCCAATGGTGGGATTAGGATTTGGATTAGCA
ATGTTGCCTGATGCAGTAATTGACAGCAGCCCAATGAATAACCAAATTTCCAGACTTAATCTTGATAAGCCTATTGAGCC
TTTTGAATTAGGTATTTGCACCCAAAAAAGAAATCTCGAACAGCCCCTAGTCCGTGCATTTTGGGCGATGTTAGAATAG

Upstream 100 bases:

>100_bases
AAGTAGGGCGTGTTTTCTTTTTGCCTACTTTTGCTTTGCACGAGCAAAGAAAAAGTAGGTCGCCATCGGCGAAACCCGAT
ATTAAATAAAAGAAGAAATT

Downstream 100 bases:

>100_bases
AATAAATAATGGTTTAAAATAAGGATTTCTTATGTTTAAAGGTATTCTCGTTTCATTATTAGCCTCGTTTTTATTTGGCT
ATATGTATTATTTTTCTACG

Product: DNA-binding transcriptional regulator IlvY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MEFTDLQIFIHLSDTKNFTKTATQNHMSPSTLSRQIQRLEDELGKTLFIRDNRQVKLTEYGEKFLQFAKTEWQNWQQFKQ
QLKDESDELCGEIKLFCSVTASYSHLPNVLKEFRQRYPKVEIQLTTGDPALALELIQAQQVDLALAGKPNNLPSSVVFHK
IDDISLSLIAPRVACLATQLLQEKPIDWQQMPFIFPVEGHARQRIEQWLREKQIKHPKIYATVAGHEGIVPMVGLGFGLA
MLPDAVIDSSPMNNQISRLNLDKPIEPFELGICTQKRNLEQPLVRAFWAMLE

Sequences:

>Translated_292_residues
MEFTDLQIFIHLSDTKNFTKTATQNHMSPSTLSRQIQRLEDELGKTLFIRDNRQVKLTEYGEKFLQFAKTEWQNWQQFKQ
QLKDESDELCGEIKLFCSVTASYSHLPNVLKEFRQRYPKVEIQLTTGDPALALELIQAQQVDLALAGKPNNLPSSVVFHK
IDDISLSLIAPRVACLATQLLQEKPIDWQQMPFIFPVEGHARQRIEQWLREKQIKHPKIYATVAGHEGIVPMVGLGFGLA
MLPDAVIDSSPMNNQISRLNLDKPIEPFELGICTQKRNLEQPLVRAFWAMLE
>Mature_292_residues
MEFTDLQIFIHLSDTKNFTKTATQNHMSPSTLSRQIQRLEDELGKTLFIRDNRQVKLTEYGEKFLQFAKTEWQNWQQFKQ
QLKDESDELCGEIKLFCSVTASYSHLPNVLKEFRQRYPKVEIQLTTGDPALALELIQAQQVDLALAGKPNNLPSSVVFHK
IDDISLSLIAPRVACLATQLLQEKPIDWQQMPFIFPVEGHARQRIEQWLREKQIKHPKIYATVAGHEGIVPMVGLGFGLA
MLPDAVIDSSPMNNQISRLNLDKPIEPFELGICTQKRNLEQPLVRAFWAMLE

Specific function: This protein activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate. IlvY is also a negative regulator of its own expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790208, Length=294, Percent_Identity=47.6190476190476, Blast_Score=288, Evalue=2e-79,
Organism=Escherichia coli, GI1787806, Length=267, Percent_Identity=25.8426966292135, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI145693105, Length=294, Percent_Identity=24.1496598639456, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI157672245, Length=148, Percent_Identity=27.027027027027, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788887, Length=301, Percent_Identity=26.578073089701, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790399, Length=124, Percent_Identity=29.8387096774194, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789639, Length=125, Percent_Identity=29.6, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786401, Length=141, Percent_Identity=26.9503546099291, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788296, Length=237, Percent_Identity=26.1603375527426, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788706, Length=175, Percent_Identity=26.8571428571429, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787601, Length=122, Percent_Identity=27.0491803278689, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788297, Length=267, Percent_Identity=23.5955056179775, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787589, Length=124, Percent_Identity=29.0322580645161, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789204, Length=289, Percent_Identity=23.5294117647059, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI145693193, Length=123, Percent_Identity=29.2682926829268, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1787530, Length=237, Percent_Identity=22.7848101265823, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788481, Length=262, Percent_Identity=20.9923664122137, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI2367136, Length=163, Percent_Identity=25.7668711656442, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788748, Length=245, Percent_Identity=23.265306122449, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33525; Mature: 33525

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFTDLQIFIHLSDTKNFTKTATQNHMSPSTLSRQIQRLEDELGKTLFIRDNRQVKLTEY
CCCCEEEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEECCCEEEHHHH
GEKFLQFAKTEWQNWQQFKQQLKDESDELCGEIKLFCSVTASYSHLPNVLKEFRQRYPKV
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
EIQLTTGDPALALELIQAQQVDLALAGKPNNLPSSVVFHKIDDISLSLIAPRVACLATQL
EEEEECCCHHHHHHHHHHHHCCEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHH
LQEKPIDWQQMPFIFPVEGHARQRIEQWLREKQIKHPKIYATVAGHEGIVPMVGLGFGLA
HHHCCCCHHHCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHH
MLPDAVIDSSPMNNQISRLNLDKPIEPFELGICTQKRNLEQPLVRAFWAMLE
HHCHHHHCCCCCCCCHHHCCCCCCCCHHHEEEECCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MEFTDLQIFIHLSDTKNFTKTATQNHMSPSTLSRQIQRLEDELGKTLFIRDNRQVKLTEY
CCCCEEEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEECCCEEEHHHH
GEKFLQFAKTEWQNWQQFKQQLKDESDELCGEIKLFCSVTASYSHLPNVLKEFRQRYPKV
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
EIQLTTGDPALALELIQAQQVDLALAGKPNNLPSSVVFHKIDDISLSLIAPRVACLATQL
EEEEECCCHHHHHHHHHHHHCCEEECCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHH
LQEKPIDWQQMPFIFPVEGHARQRIEQWLREKQIKHPKIYATVAGHEGIVPMVGLGFGLA
HHHCCCCHHHCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHH
MLPDAVIDSSPMNNQISRLNLDKPIEPFELGICTQKRNLEQPLVRAFWAMLE
HHCHHHHCCCCCCCCHHHCCCCCCCCHHHEEEECCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]