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The map label for this gene is pepD [H]

Identifier: 148827851

GI number: 148827851

Start: 1213417

End: 1214871

Strand: Direct

Name: pepD [H]

Synonym: CGSHiGG_06655

Alternate gene names: 148827851

Gene position: 1213417-1214871 (Clockwise)

Preceding gene: 148827845

Following gene: 148827853

Centisome position: 64.3

GC content: 40.14

Gene sequence:

>1455_bases
ATGTCTGAAATTACAACACTTCAACCCTCATTGTTATGGAAATGGTTTGATCAAATTTGTGCAATCCCTCATCCTTCTCA
TTATGAAGATGCGTTAGCTAACTTTATTGTAAATTGGGCGAAAGAAAAGCATTTTTTTGTGGAACGCGATGAAGTAGGCA
ATGTTCTCATTCGTAAACCCGCGACGAAAGGAATGGAAAATCACACACCTGTTGTTCTACAAGCGCACTTAGATATGGTG
CCACAGGCTAATGAAGGTAACCCGCATGATTTTACCAAAGATCCTATTCAACCTTATATTGATGGAGAATGGGTAAAAGC
GCGAGGTACAACATTAGGATCTGACAATGGTATCGGTTTAGCCTCTACTCTAGCTGTGTTAGAAAGCAATGATTTAGCGC
ATCCACCTCTTGAAGTGCTTTTAACAATGACAGAAGAAACGGGGATGGATGGTGCGAAAGACCTGCGTCATAACTGGTTA
CAATCTGAAATTTTAATCAATACAGATACCGAAGAAATTGGCGAAATTTACATTGGTTGTGCGGGTGGCATTAACGCAAA
CTTTGAAATTCCAGTTCAATATGAAACCAATACCTTTGAGCATAGTGTACAAATTACGCTTAAAGGTTTACGCGGCGGTC
ATTCTGGTGTTGATATTCATACAGGACGTGCAAATGCAATTAAAGTGTTAGCGCGAGTATTAGCAAAACTCTCTCAAAAT
CAACCGCACTTTGCTCTCTCTGAAATTCGTGGTGGCTCAATTCGTAATGCAATTCCACGAGAAGCAGCGGCTGTGTTAGC
CTTTAATGGCGATGTAAAAGCCATAGAAGGTGCGGTAGAAAATCTCGCAGTTGTGCTTAAAGAAGAATTAGCCATTGCAG
AACCTAATTTCACACTTTTTGTAGAATCCGCAGAAAAAGCTCTTACCGTATTCACAGCACAAAGCACTCAAACGGTTATT
AACGCCCTCAACGTATTGCCAAACGGCGTAATCCGCAATAGTGATGTAGTTAAAAATGTCGTAGAAAGTTCATTAAGCGT
TGGCGTATTGAAAACAGAAGGCAATGTTGTAAAAAGCACCATTTTGGTTCGTTCATTAATTGAAAGCGGTAAATATTACG
TAACTGAAATGCTCAGCTCACTTGCAATCTTAGCAAATGCAAAAGTCGAGTTTTCTGCACCTTATCCGGGCTGGCAACCT
GTAAATGACTCAACAATCTTAGACGTTACTCGCAAACATTATGCTGAAGTGCTAGGCGAGCAACCTGTAGTGAAAGTCAT
TCACGCAGGATTAGAATGTGGTCTTTTAAAAGAACATTATCCAAACATTGAAATGATTTCTGTTGGGCCAACAATACGAA
ATGCTCACTCACCAGATGAAAAAGTGGAAATCGCAACAGTACAAACCTATTGGGATTTATTGACAAGAGTACTTGCCGAT
ATTCCTGCGAAGTAA

Upstream 100 bases:

>100_bases
TTAGTTTAAATTTATCGAGAAATAAAAAATTGCGTAAGGATAACCCGAAATGGCGTTTTATGCTATTATTTCGTAAATAT
TTTCAGTAAAAGGAGCAATT

Downstream 100 bases:

>100_bases
TCTAATATTAATTAAAAGTGCGGTTAAAATTTTTTTTGTTTTAACCGCTCTTTTATTTTTTTCGTTTCGCTCTTGGGTGC
GCCTGATCGTACACTTCCGC

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Beta-alanyl-histidine dipeptidase; Carnosinase; Peptidase D; Xaa-His dipeptidase; X-His dipeptidase [H]

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MSEITTLQPSLLWKWFDQICAIPHPSHYEDALANFIVNWAKEKHFFVERDEVGNVLIRKPATKGMENHTPVVLQAHLDMV
PQANEGNPHDFTKDPIQPYIDGEWVKARGTTLGSDNGIGLASTLAVLESNDLAHPPLEVLLTMTEETGMDGAKDLRHNWL
QSEILINTDTEEIGEIYIGCAGGINANFEIPVQYETNTFEHSVQITLKGLRGGHSGVDIHTGRANAIKVLARVLAKLSQN
QPHFALSEIRGGSIRNAIPREAAAVLAFNGDVKAIEGAVENLAVVLKEELAIAEPNFTLFVESAEKALTVFTAQSTQTVI
NALNVLPNGVIRNSDVVKNVVESSLSVGVLKTEGNVVKSTILVRSLIESGKYYVTEMLSSLAILANAKVEFSAPYPGWQP
VNDSTILDVTRKHYAEVLGEQPVVKVIHAGLECGLLKEHYPNIEMISVGPTIRNAHSPDEKVEIATVQTYWDLLTRVLAD
IPAK

Sequences:

>Translated_484_residues
MSEITTLQPSLLWKWFDQICAIPHPSHYEDALANFIVNWAKEKHFFVERDEVGNVLIRKPATKGMENHTPVVLQAHLDMV
PQANEGNPHDFTKDPIQPYIDGEWVKARGTTLGSDNGIGLASTLAVLESNDLAHPPLEVLLTMTEETGMDGAKDLRHNWL
QSEILINTDTEEIGEIYIGCAGGINANFEIPVQYETNTFEHSVQITLKGLRGGHSGVDIHTGRANAIKVLARVLAKLSQN
QPHFALSEIRGGSIRNAIPREAAAVLAFNGDVKAIEGAVENLAVVLKEELAIAEPNFTLFVESAEKALTVFTAQSTQTVI
NALNVLPNGVIRNSDVVKNVVESSLSVGVLKTEGNVVKSTILVRSLIESGKYYVTEMLSSLAILANAKVEFSAPYPGWQP
VNDSTILDVTRKHYAEVLGEQPVVKVIHAGLECGLLKEHYPNIEMISVGPTIRNAHSPDEKVEIATVQTYWDLLTRVLAD
IPAK
>Mature_483_residues
SEITTLQPSLLWKWFDQICAIPHPSHYEDALANFIVNWAKEKHFFVERDEVGNVLIRKPATKGMENHTPVVLQAHLDMVP
QANEGNPHDFTKDPIQPYIDGEWVKARGTTLGSDNGIGLASTLAVLESNDLAHPPLEVLLTMTEETGMDGAKDLRHNWLQ
SEILINTDTEEIGEIYIGCAGGINANFEIPVQYETNTFEHSVQITLKGLRGGHSGVDIHTGRANAIKVLARVLAKLSQNQ
PHFALSEIRGGSIRNAIPREAAAVLAFNGDVKAIEGAVENLAVVLKEELAIAEPNFTLFVESAEKALTVFTAQSTQTVIN
ALNVLPNGVIRNSDVVKNVVESSLSVGVLKTEGNVVKSTILVRSLIESGKYYVTEMLSSLAILANAKVEFSAPYPGWQPV
NDSTILDVTRKHYAEVLGEQPVVKVIHAGLECGLLKEHYPNIEMISVGPTIRNAHSPDEKVEIATVQTYWDLLTRVLADI
PAK

Specific function: Dipeptidase with broad substrate specificity [H]

COG id: COG2195

COG function: function code E; Di- and tripeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20C family [H]

Homologues:

Organism=Escherichia coli, GI1786432, Length=487, Percent_Identity=56.2628336755647, Blast_Score=540, Evalue=1e-155,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002933
- InterPro:   IPR011650
- InterPro:   IPR001160 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.13.3 [H]

Molecular weight: Translated: 52943; Mature: 52812

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEITTLQPSLLWKWFDQICAIPHPSHYEDALANFIVNWAKEKHFFVERDEVGNVLIRKP
CCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHCCEEEECC
ATKGMENHTPVVLQAHLDMVPQANEGNPHDFTKDPIQPYIDGEWVKARGTTLGSDNGIGL
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCH
ASTLAVLESNDLAHPPLEVLLTMTEETGMDGAKDLRHNWLQSEILINTDTEEIGEIYIGC
HHHHHHHCCCCCCCCCHHHEEEEHHHCCCCHHHHHHHHHCCCEEEEECCHHHHCCEEEEE
AGGINANFEIPVQYETNTFEHSVQITLKGLRGGHSGVDIHTGRANAIKVLARVLAKLSQN
CCCCCCCEEEEEEECCCCEEEEEEEEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHCC
QPHFALSEIRGGSIRNAIPREAAAVLAFNGDVKAIEGAVENLAVVLKEELAIAEPNFTLF
CCCEEHHHCCCCCHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHEECCCEEEE
VESAEKALTVFTAQSTQTVINALNVLPNGVIRNSDVVKNVVESSLSVGVLKTEGNVVKST
EECCCCEEEEEECCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEECCCCHHHHH
ILVRSLIESGKYYVTEMLSSLAILANAKVEFSAPYPGWQPVNDSTILDVTRKHYAEVLGE
HHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCC
QPVVKVIHAGLECGLLKEHYPNIEMISVGPTIRNAHSPDEKVEIATVQTYWDLLTRVLAD
CHHHHHHHCCCCCCCHHHHCCCEEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHH
IPAK
CCCC
>Mature Secondary Structure 
SEITTLQPSLLWKWFDQICAIPHPSHYEDALANFIVNWAKEKHFFVERDEVGNVLIRKP
CCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHCCEEEECC
ATKGMENHTPVVLQAHLDMVPQANEGNPHDFTKDPIQPYIDGEWVKARGTTLGSDNGIGL
CCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCH
ASTLAVLESNDLAHPPLEVLLTMTEETGMDGAKDLRHNWLQSEILINTDTEEIGEIYIGC
HHHHHHHCCCCCCCCCHHHEEEEHHHCCCCHHHHHHHHHCCCEEEEECCHHHHCCEEEEE
AGGINANFEIPVQYETNTFEHSVQITLKGLRGGHSGVDIHTGRANAIKVLARVLAKLSQN
CCCCCCCEEEEEEECCCCEEEEEEEEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHCC
QPHFALSEIRGGSIRNAIPREAAAVLAFNGDVKAIEGAVENLAVVLKEELAIAEPNFTLF
CCCEEHHHCCCCCHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHEECCCEEEE
VESAEKALTVFTAQSTQTVINALNVLPNGVIRNSDVVKNVVESSLSVGVLKTEGNVVKST
EECCCCEEEEEECCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEECCCCHHHHH
ILVRSLIESGKYYVTEMLSSLAILANAKVEFSAPYPGWQPVNDSTILDVTRKHYAEVLGE
HHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCC
QPVVKVIHAGLECGLLKEHYPNIEMISVGPTIRNAHSPDEKVEIATVQTYWDLLTRVLAD
CHHHHHHHCCCCCCCHHHHCCCEEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHH
IPAK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]