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The map label for this gene is glmU [H]

Identifier: 148827819

GI number: 148827819

Start: 1179426

End: 1180796

Strand: Direct

Name: glmU [H]

Synonym: CGSHiGG_06470

Alternate gene names: 148827819

Gene position: 1179426-1180796 (Clockwise)

Preceding gene: 148827818

Following gene: 148827825

Centisome position: 62.5

GC content: 38.22

Gene sequence:

>1371_bases
ATGACAAAAAAAGCATTAAGTGCGGTAATTTTAGCAGCTGGAAAAGGCACTCGTATGTATTCTGATTTACCCAAAGTGCT
ACATACAATCGCGGGTAAACCAATGGTAAAACACGTGATTGATACTGCCCATCAATTAGGCGCAGAAAATATTCATTTAA
TCTATGGTCACGGTGGGGACTTAATGCGTTCCCATCTTGCAAATGAACAAGTAAATTGGGTATTACAAACAGAACAACTT
GGTACTGCACATGCAGTTCAACAATCAGCACCTTTCTTTAAGGATAACGAAAATATTGTTGTACTTTACGGCGATGCACC
ATTAATAACTAAAGAAACATTAGAAAAATTAATTGAAGCGAAACCAGAAAATGGCATTGCATTGCTTACCGTAAATTTAG
ATAACCCAACAGGCTATGGACGAATTATCCGTGAAAATGGGAATGTTGTAGCCATTGTAGAACAAAAAGATGCAAATGCA
GATCAACTAAATATTAAAGAAGTAAATACTGGCGTTATGGTATCTGATGGTGCAAGTTTCAAAAAATGGCTAGCTCGTGT
AGGCAATAATAATGCTCAAGGCGAATATTACTTAACGGATCTTATTGCTCTCGCAAATCAAGATAATTGTCAAGTTGTTG
CTGTACAAGCAACAGATGTCATGGAAGTTGAAGGTGCAAATAATCGCTTACAATTAGCCGCACTTGAACGTTATCTCCAA
AATAAACAAGCCTCAAAATTATTACTTGAAGGCGTAATGATCTACGATCCCGCTCGTTTTGACCTACGTGGAACATTAGA
GCATGGAAAAGATGTGGAAATCGATGTTAATGTTATTATCGAAGGTAATGTTAAACTCGGTGATCGCGTAAAAATTGGCG
CAGGTTGCGTATTGAAAAATGTTGTTATTGGCAATGATGTAGAAATAAAACCCTATTCAGTGCTAGAGGATTCTGTAGTG
GGAGAAAAAGCCGCAATTGGTCCATTTTCTCGTTTACGCCCAGGTGCAGAACTCGCAGCTGAAACGCATGTCGGTAACTT
TGTAGAAATTAAAAAATCTACCGTTGGTAAAGGTTCTAAAGTAAATCACCTAACCTATGTTGGCGATTCAGAAATAGGCT
CAAATTGTAATATTGGTGCGGGTGTCATCACCTGCAACTACGATGGTGCAAATAAATTTAAAACGATCATCGGTGATGAT
GTGTTTGTGGGATCTGATACACAATTAGTTGCGCCAGTGAAAGTCGCAAATGGCGCAACTATTGGTGCTGGGACTACAAT
TACACGTGATGTTGGCGAAAATGAATTAGTGATTACAAGAGTTGCTCAACGACATATTCAAGGTTGGCAACGACCAATAA
AGAAAAAATAA

Upstream 100 bases:

>100_bases
ATATAAAAGTTTGTTATAGCTTTTACTTAAAAACTTACCATTTGCTATCTTTCTAAGATAGAATATTACCCGTTGTTATT
GATGAATAAAGAGAAAATTT

Downstream 100 bases:

>100_bases
AACAGAATAAAAAAATCCTACGTATTATCGTAGGATTTTTTTATAAACCAATTTTACAAATCGTAATTAAAATCACATAA
AAAATGACCGCACTTAATGT

Product: bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MTKKALSAVILAAGKGTRMYSDLPKVLHTIAGKPMVKHVIDTAHQLGAENIHLIYGHGGDLMRSHLANEQVNWVLQTEQL
GTAHAVQQSAPFFKDNENIVVLYGDAPLITKETLEKLIEAKPENGIALLTVNLDNPTGYGRIIRENGNVVAIVEQKDANA
DQLNIKEVNTGVMVSDGASFKKWLARVGNNNAQGEYYLTDLIALANQDNCQVVAVQATDVMEVEGANNRLQLAALERYLQ
NKQASKLLLEGVMIYDPARFDLRGTLEHGKDVEIDVNVIIEGNVKLGDRVKIGAGCVLKNVVIGNDVEIKPYSVLEDSVV
GEKAAIGPFSRLRPGAELAAETHVGNFVEIKKSTVGKGSKVNHLTYVGDSEIGSNCNIGAGVITCNYDGANKFKTIIGDD
VFVGSDTQLVAPVKVANGATIGAGTTITRDVGENELVITRVAQRHIQGWQRPIKKK

Sequences:

>Translated_456_residues
MTKKALSAVILAAGKGTRMYSDLPKVLHTIAGKPMVKHVIDTAHQLGAENIHLIYGHGGDLMRSHLANEQVNWVLQTEQL
GTAHAVQQSAPFFKDNENIVVLYGDAPLITKETLEKLIEAKPENGIALLTVNLDNPTGYGRIIRENGNVVAIVEQKDANA
DQLNIKEVNTGVMVSDGASFKKWLARVGNNNAQGEYYLTDLIALANQDNCQVVAVQATDVMEVEGANNRLQLAALERYLQ
NKQASKLLLEGVMIYDPARFDLRGTLEHGKDVEIDVNVIIEGNVKLGDRVKIGAGCVLKNVVIGNDVEIKPYSVLEDSVV
GEKAAIGPFSRLRPGAELAAETHVGNFVEIKKSTVGKGSKVNHLTYVGDSEIGSNCNIGAGVITCNYDGANKFKTIIGDD
VFVGSDTQLVAPVKVANGATIGAGTTITRDVGENELVITRVAQRHIQGWQRPIKKK
>Mature_455_residues
TKKALSAVILAAGKGTRMYSDLPKVLHTIAGKPMVKHVIDTAHQLGAENIHLIYGHGGDLMRSHLANEQVNWVLQTEQLG
TAHAVQQSAPFFKDNENIVVLYGDAPLITKETLEKLIEAKPENGIALLTVNLDNPTGYGRIIRENGNVVAIVEQKDANAD
QLNIKEVNTGVMVSDGASFKKWLARVGNNNAQGEYYLTDLIALANQDNCQVVAVQATDVMEVEGANNRLQLAALERYLQN
KQASKLLLEGVMIYDPARFDLRGTLEHGKDVEIDVNVIIEGNVKLGDRVKIGAGCVLKNVVIGNDVEIKPYSVLEDSVVG
EKAAIGPFSRLRPGAELAAETHVGNFVEIKKSTVGKGSKVNHLTYVGDSEIGSNCNIGAGVITCNYDGANKFKTIIGDDV
FVGSDTQLVAPVKVANGATIGAGTTITRDVGENELVITRVAQRHIQGWQRPIKKK

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=456, Percent_Identity=67.9824561403509, Blast_Score=659, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR018357
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 49182; Mature: 49051

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKALSAVILAAGKGTRMYSDLPKVLHTIAGKPMVKHVIDTAHQLGAENIHLIYGHGGD
CCHHHHEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCHH
LMRSHLANEQVNWVLQTEQLGTAHAVQQSAPFFKDNENIVVLYGDAPLITKETLEKLIEA
HHHHHHCCCCEEEEEEECCCCCHHHHHHCCCCEECCCCEEEEECCCCCCCHHHHHHHHHC
KPENGIALLTVNLDNPTGYGRIIRENGNVVAIVEQKDANADQLNIKEVNTGVMVSDGASF
CCCCCEEEEEEECCCCCCCCEEEEECCCEEEEEECCCCCCCEEEEEEECCCEEEECCCHH
KKWLARVGNNNAQGEYYLTDLIALANQDNCQVVAVQATDVMEVEGANNRLQLAALERYLQ
HHHHHHHCCCCCCCCEEEEEHHHHCCCCCCEEEEEECCCEEEECCCCCEEHHHHHHHHHH
NKQASKLLLEGVMIYDPARFDLRGTLEHGKDVEIDVNVIIEGNVKLGDRVKIGAGCVLKN
CHHHHHHHHCCEEEECCCCCCEEEECCCCCCEEEEEEEEEECCEEECCEEEECCCEEEEE
VVIGNDVEIKPYSVLEDSVVGEKAAIGPFSRLRPGAELAAETHVGNFVEIKKSTVGKGSK
EEECCCCEECCHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHCCCCEEEEEHHHCCCCCC
VNHLTYVGDSEIGSNCNIGAGVITCNYDGANKFKTIIGDDVFVGSDTQLVAPVKVANGAT
CEEEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHEECCCEEECCCCEEEEEEEECCCCE
IGAGTTITRDVGENELVITRVAQRHIQGWQRPIKKK
ECCCCEEEECCCCCCEEEHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TKKALSAVILAAGKGTRMYSDLPKVLHTIAGKPMVKHVIDTAHQLGAENIHLIYGHGGD
CHHHHEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCHH
LMRSHLANEQVNWVLQTEQLGTAHAVQQSAPFFKDNENIVVLYGDAPLITKETLEKLIEA
HHHHHHCCCCEEEEEEECCCCCHHHHHHCCCCEECCCCEEEEECCCCCCCHHHHHHHHHC
KPENGIALLTVNLDNPTGYGRIIRENGNVVAIVEQKDANADQLNIKEVNTGVMVSDGASF
CCCCCEEEEEEECCCCCCCCEEEEECCCEEEEEECCCCCCCEEEEEEECCCEEEECCCHH
KKWLARVGNNNAQGEYYLTDLIALANQDNCQVVAVQATDVMEVEGANNRLQLAALERYLQ
HHHHHHHCCCCCCCCEEEEEHHHHCCCCCCEEEEEECCCEEEECCCCCEEHHHHHHHHHH
NKQASKLLLEGVMIYDPARFDLRGTLEHGKDVEIDVNVIIEGNVKLGDRVKIGAGCVLKN
CHHHHHHHHCCEEEECCCCCCEEEECCCCCCEEEEEEEEEECCEEECCEEEECCCEEEEE
VVIGNDVEIKPYSVLEDSVVGEKAAIGPFSRLRPGAELAAETHVGNFVEIKKSTVGKGSK
EEECCCCEECCHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHCCCCEEEEEHHHCCCCCC
VNHLTYVGDSEIGSNCNIGAGVITCNYDGANKFKTIIGDDVFVGSDTQLVAPVKVANGAT
CEEEEEECCCCCCCCCCCCCEEEEEECCCCCHHHHEECCCEEECCCCEEEEEEEECCCCE
IGAGTTITRDVGENELVITRVAQRHIQGWQRPIKKK
ECCCCEEEECCCCCCEEEHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA