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The map label for this gene is trpS [H]

Identifier: 148827814

GI number: 148827814

Start: 1174932

End: 1175936

Strand: Reverse

Name: trpS [H]

Synonym: CGSHiGG_06445

Alternate gene names: 148827814

Gene position: 1175936-1174932 (Counterclockwise)

Preceding gene: 148827820

Following gene: 148827813

Centisome position: 62.31

GC content: 39.3

Gene sequence:

>1005_bases
ATGGCAAAACCAATTGTTTTTAGTGGCGTGCAGCCTTCTGGTGAATTAACTATCGGAAATTATTTGGGTGCGTTGCGCAA
CTGGGTGAAAATGCAAGAGGATTATGAATGTATTTTCTGCGTAGTTGATTTACATGCGATCACTGTTCGTCAAGATCCTG
TTGCCCTTCGCAAAGCAACCCTTGATGTGCTTGCACTTTATTTAGCGTGCGGAATTGATCCAAATAAAAGTACTATTTTT
GTTCAATCTCACGTTCCAGAACACACGCAATTAAGCTGGGTGTTAAACTGTTACACCTATTTCGGTGAAATGAGCCGAAT
GACGCAATTTAAAGATAAATCAGCGCGTTATGCAGAAAATATTAACGTGGGTTTGTTTGATTACCCAGTGTTAATGGCGG
CGGATATTTTACTTTATCAAGCAAAAAGCGTGCCTGTTGGCGATGACCAAAAACAACACTTAGAAATTACGCGTGATATT
GCAAACCGCTTTAATGCGCTTTATGGCAATATTTTCACTATTCCTGAAATTTTCATTGGAAAAGCAGGCGCGCGTATTAT
GTCATTGCAAGATCCTGAAAAGAAAATGTCAAAATCAGATGATAACCGCAACAACGTGGTGACACTTTTAGAAGATCCAA
AATCTGTGGCGAAGAAAATTAAACGTGCCGTAACGGATTCAGATGAGCCGCCAGTTGTTCGTTATGATGTGAAAAATAAA
GCGGGTGTATCCAATCTTTTAGATATTCTTTCTGCGGTTACAGATAAGCCAATTGCTGATCTTGAAAAAGAATTTGAAGG
TAAAATGTACGGACATTTAAAAACAGCAGTGGCGGATGAAGTCTCAACCCTACTTGCTGGTTTACAAGAACGTTTCCATC
AATATCGTAATGATGAAGCTTTATTAGATAATATCTTACGACAAGGTGCGGAAAAAGCTCGTGCAAAAGCGCAAGAAACC
TTGGCTAAAGTGTATGAAGCAGTGGGTTTTGTTGCTGCAAAATAA

Upstream 100 bases:

>100_bases
AAATATAGCATTTTTAACCTAGCTTTTGAACTCGAACATTAAAAAAGCCTAGAGTTTCTGATATGATGTGTGAACAGTTT
TAAGGTATTAAGGATTGATT

Downstream 100 bases:

>100_bases
TCTGAATAAAAGGATAATATTATGGCAATTCAAACTGAAAAACCGATTGAATGTGTAGGTTGTAATACTTTTGATATGAA
ATCACTTTTCGATAATCGTG

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MAKPIVFSGVQPSGELTIGNYLGALRNWVKMQEDYECIFCVVDLHAITVRQDPVALRKATLDVLALYLACGIDPNKSTIF
VQSHVPEHTQLSWVLNCYTYFGEMSRMTQFKDKSARYAENINVGLFDYPVLMAADILLYQAKSVPVGDDQKQHLEITRDI
ANRFNALYGNIFTIPEIFIGKAGARIMSLQDPEKKMSKSDDNRNNVVTLLEDPKSVAKKIKRAVTDSDEPPVVRYDVKNK
AGVSNLLDILSAVTDKPIADLEKEFEGKMYGHLKTAVADEVSTLLAGLQERFHQYRNDEALLDNILRQGAEKARAKAQET
LAKVYEAVGFVAAK

Sequences:

>Translated_334_residues
MAKPIVFSGVQPSGELTIGNYLGALRNWVKMQEDYECIFCVVDLHAITVRQDPVALRKATLDVLALYLACGIDPNKSTIF
VQSHVPEHTQLSWVLNCYTYFGEMSRMTQFKDKSARYAENINVGLFDYPVLMAADILLYQAKSVPVGDDQKQHLEITRDI
ANRFNALYGNIFTIPEIFIGKAGARIMSLQDPEKKMSKSDDNRNNVVTLLEDPKSVAKKIKRAVTDSDEPPVVRYDVKNK
AGVSNLLDILSAVTDKPIADLEKEFEGKMYGHLKTAVADEVSTLLAGLQERFHQYRNDEALLDNILRQGAEKARAKAQET
LAKVYEAVGFVAAK
>Mature_333_residues
AKPIVFSGVQPSGELTIGNYLGALRNWVKMQEDYECIFCVVDLHAITVRQDPVALRKATLDVLALYLACGIDPNKSTIFV
QSHVPEHTQLSWVLNCYTYFGEMSRMTQFKDKSARYAENINVGLFDYPVLMAADILLYQAKSVPVGDDQKQHLEITRDIA
NRFNALYGNIFTIPEIFIGKAGARIMSLQDPEKKMSKSDDNRNNVVTLLEDPKSVAKKIKRAVTDSDEPPVVRYDVKNKA
GVSNLLDILSAVTDKPIADLEKEFEGKMYGHLKTAVADEVSTLLAGLQERFHQYRNDEALLDNILRQGAEKARAKAQETL
AKVYEAVGFVAAK

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=331, Percent_Identity=41.3897280966767, Blast_Score=273, Evalue=2e-73,
Organism=Homo sapiens, GI41352700, Length=176, Percent_Identity=51.1363636363636, Blast_Score=204, Evalue=1e-52,
Organism=Escherichia coli, GI1789786, Length=332, Percent_Identity=78.6144578313253, Blast_Score=558, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI71982800, Length=334, Percent_Identity=36.2275449101796, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI71982793, Length=334, Percent_Identity=36.2275449101796, Blast_Score=217, Evalue=6e-57,
Organism=Saccharomyces cerevisiae, GI6320474, Length=345, Percent_Identity=41.1594202898551, Blast_Score=248, Evalue=1e-66,
Organism=Drosophila melanogaster, GI24666151, Length=329, Percent_Identity=41.0334346504559, Blast_Score=253, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37336; Mature: 37205

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKPIVFSGVQPSGELTIGNYLGALRNWVKMQEDYECIFCVVDLHAITVRQDPVALRKAT
CCCCEEEECCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEEHHHEEECCCCHHHHHHH
LDVLALYLACGIDPNKSTIFVQSHVPEHTQLSWVLNCYTYFGEMSRMTQFKDKSARYAEN
HHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
INVGLFDYPVLMAADILLYQAKSVPVGDDQKQHLEITRDIANRFNALYGNIFTIPEIFIG
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHC
KAGARIMSLQDPEKKMSKSDDNRNNVVTLLEDPKSVAKKIKRAVTDSDEPPVVRYDVKNK
CCCCEEECCCCHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCEEEEECCCC
AGVSNLLDILSAVTDKPIADLEKEFEGKMYGHLKTAVADEVSTLLAGLQERFHQYRNDEA
CCHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LLDNILRQGAEKARAKAQETLAKVYEAVGFVAAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKPIVFSGVQPSGELTIGNYLGALRNWVKMQEDYECIFCVVDLHAITVRQDPVALRKAT
CCCEEEECCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEEHHHEEECCCCHHHHHHH
LDVLALYLACGIDPNKSTIFVQSHVPEHTQLSWVLNCYTYFGEMSRMTQFKDKSARYAEN
HHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
INVGLFDYPVLMAADILLYQAKSVPVGDDQKQHLEITRDIANRFNALYGNIFTIPEIFIG
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHC
KAGARIMSLQDPEKKMSKSDDNRNNVVTLLEDPKSVAKKIKRAVTDSDEPPVVRYDVKNK
CCCCEEECCCCHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCEEEEECCCC
AGVSNLLDILSAVTDKPIADLEKEFEGKMYGHLKTAVADEVSTLLAGLQERFHQYRNDEA
CCHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LLDNILRQGAEKARAKAQETLAKVYEAVGFVAAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]