Click here to switch to the map view.

The map label for this gene is cpdB [H]

Identifier: 148827803

GI number: 148827803

Start: 1160928

End: 1161605

Strand: Reverse

Name: cpdB [H]

Synonym: CGSHiGG_06380

Alternate gene names: 148827803

Gene position: 1161605-1160928 (Counterclockwise)

Preceding gene: 148827811

Following gene: 148827802

Centisome position: 61.55

GC content: 33.78

Gene sequence:

>678_bases
ATGAAAGAAGTTTCTCTAGTAAAAAATTATACTCCTAAAGAATATCAGCAGCATGCATCTTGCCCTCATAGTCAAATTTC
TAAAAATAAAATGGTATTAGGCATCAGTTTTGCAATTATTACCTTTTATATGGTTGTTGAATTTCTAGGGGGATATTGGT
TTAACAGCCTTACTTTGATGGCTGATGCTGGGCATATGGCAAATGATAGTTTATCTATTTTTTTAGCATGGATTGGGTTA
TTTTTAAGTCTAAAATGGCAAAAATGGTTAGCTTTAATCAATGGAATTTCATTAGTTTGGGTCGCTATTTGGATTTTTAT
TGAGGCTGTAACACGTTGGCAGGCTCCGATAGAAATAGCCGCTTTGCCAATGTTAGGTGTAGCTTTACTAGGGTTTGGGA
TTAATTTGTTGGTAGCTTTTATAATGCTAAAAAGTAATCGCCATAATTTGAATATTCGTGCAGCATATTTGCATGTTTTA
GTAGATTTATTTGGTTCGGTTGTTGCTATTATTGCAGGAATAAGTGCTTGGTGGTTAAATTGGCAGTGGGTTGATGTAGT
TGCTAGTGGTATCTTAAGCATTTTTGTATTACAAAGCGGTATTTCTACAGTTTTTCAAGCTATTAAATCCTTATATAGTA
GCGATGACAATTCATTGCCGAATGATCATTCTCATTAA

Upstream 100 bases:

>100_bases
TTTTAAACAATTAATTTTATTAAATGTACGTTTTATGATTTGACTTTGTAGTTACTACAGGTTTTATGCTTCCTTCAAAT
TAAATAGTTAAGGAAATAAA

Downstream 100 bases:

>100_bases
AGTAAAAAATTGCTTGAGGAAATAATGAAAATTAATGAATTAAGTAAATCTACACATACTAATATTGAAACTATTCGCTA
CTATGAGAAACAAGGAGTAT

Product: bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKEVSLVKNYTPKEYQQHASCPHSQISKNKMVLGISFAIITFYMVVEFLGGYWFNSLTLMADAGHMANDSLSIFLAWIGL
FLSLKWQKWLALINGISLVWVAIWIFIEAVTRWQAPIEIAALPMLGVALLGFGINLLVAFIMLKSNRHNLNIRAAYLHVL
VDLFGSVVAIIAGISAWWLNWQWVDVVASGILSIFVLQSGISTVFQAIKSLYSSDDNSLPNDHSH

Sequences:

>Translated_225_residues
MKEVSLVKNYTPKEYQQHASCPHSQISKNKMVLGISFAIITFYMVVEFLGGYWFNSLTLMADAGHMANDSLSIFLAWIGL
FLSLKWQKWLALINGISLVWVAIWIFIEAVTRWQAPIEIAALPMLGVALLGFGINLLVAFIMLKSNRHNLNIRAAYLHVL
VDLFGSVVAIIAGISAWWLNWQWVDVVASGILSIFVLQSGISTVFQAIKSLYSSDDNSLPNDHSH
>Mature_225_residues
MKEVSLVKNYTPKEYQQHASCPHSQISKNKMVLGISFAIITFYMVVEFLGGYWFNSLTLMADAGHMANDSLSIFLAWIGL
FLSLKWQKWLALINGISLVWVAIWIFIEAVTRWQAPIEIAALPMLGVALLGFGINLLVAFIMLKSNRHNLNIRAAYLHVL
VDLFGSVVAIIAGISAWWLNWQWVDVVASGILSIFVLQSGISTVFQAIKSLYSSDDNSLPNDHSH

Specific function: Involved in divalent cation and potassium homeostasis in the cell. Catalyzes the active efflux of zinc, cadmium and cobalt, in exchange for potassium and H(+) ions [H]

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786966, Length=173, Percent_Identity=35.8381502890173, Blast_Score=80, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 25170; Mature: 25170

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEVSLVKNYTPKEYQQHASCPHSQISKNKMVLGISFAIITFYMVVEFLGGYWFNSLTLM
CCCCHHHHCCCHHHHHHHCCCCHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHE
ADAGHMANDSLSIFLAWIGLFLSLKWQKWLALINGISLVWVAIWIFIEAVTRWQAPIEIA
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ALPMLGVALLGFGINLLVAFIMLKSNRHNLNIRAAYLHVLVDLFGSVVAIIAGISAWWLN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
WQWVDVVASGILSIFVLQSGISTVFQAIKSLYSSDDNSLPNDHSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKEVSLVKNYTPKEYQQHASCPHSQISKNKMVLGISFAIITFYMVVEFLGGYWFNSLTLM
CCCCHHHHCCCHHHHHHHCCCCHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHE
ADAGHMANDSLSIFLAWIGLFLSLKWQKWLALINGISLVWVAIWIFIEAVTRWQAPIEIA
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ALPMLGVALLGFGINLLVAFIMLKSNRHNLNIRAAYLHVLVDLFGSVVAIIAGISAWWLN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
WQWVDVVASGILSIFVLQSGISTVFQAIKSLYSSDDNSLPNDHSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA