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The map label for this gene is tolA [H]

Identifier: 148827588

GI number: 148827588

Start: 927554

End: 928786

Strand: Reverse

Name: tolA [H]

Synonym: CGSHiGG_05075

Alternate gene names: 148827588

Gene position: 928786-927554 (Counterclockwise)

Preceding gene: 148827589

Following gene: 148827587

Centisome position: 49.22

GC content: 42.82

Gene sequence:

>1233_bases
GTGCAAAATAATCGACAAAAGAAAGGAATCAATGCTTTTGCTATTTCTATCCTTTTGCACTTTATCTTGTTTGGCTTATT
GATTTTAAGTTCACTTTATCACACTGTTGAAATTATGGGTGGAGGAGAAGGTGAAGGAGATGTAATAGGGGCAGTGATTG
TTGATACTGGTACGGCTGCTCAGGAATGGGGGCGTATTCAACAACAAAAAAAAGGGCAATCGGATAAACAAAAACGCCCA
GAACCTGTTGTGGAAGAAAAACCACCTGAGCCTAATCAAGAAGAGATTAAGCATCAACAAGAAGTTCAACGACAAGAAGA
GTTAAAACGTCAGCAAGAAATAAAAAAACAACAAGAGCAAGCTCGTCAAGAAGCGTTGGAAAAACAGAAGCAAGCTGAAG
AGGCTAGGGCTAAACAAGCGGCTGAAGCTGCAAAATTAAAAGCAGATGCAGAGGCTAAACGTTTAGCTGCTGCGGCAAAA
CAAGCTGAAGAAGAGGCTAAAGCGAAAGCAGCAGAAATTGCTGCTCAAAAAGCAAAACAAGAGGCGGAAGCTAAGGCGAA
ACTAGAAGCCGAAGCTAAGGCAAAAGCCGTTGCTGAAGCTAAAGCAAAGGCTGAAGCGGAGGCAAAAGCGAAAGCGGCAG
CTGAGGCGAAAGCTAAAGCTGAGGCTGAGGCAAAAGCAAAAGCTGAGGCAAAAGCAAAAGCTGAGGCTAAAGCAAAGGCT
GAAGCTGAGGCTAAAGCAAAAGCTGAAGCGGAGGCAAAAGCGAAAGCGGCAGCAGAGGCAAAAGCAAAAGCTGATGCAGA
AGCTAAAGCTGCTACGGAAGCGAAACGTAAAGCAGATCAAGCAAGCCTAGATGATTTCTTAAATGGCGGAGATATTGGTG
GCGGTAGTGCATCTAAAGGGGGAAACACAAATAAAGGTGGAACTCAAGGTAGCGGTGCTGCACTTGGCTCTGGCGATGGT
GGTAAGGTTGGGGATCAATACGCAGGTGTAATTAAGAAAGAGATTCAACGTCGTTTCTTAAAAGATCCAAATTTTGCAGG
AAAGGTTTGTCGTATTAAAATTCAATTAGGTCGAGATGGCACAATCTTGGGGTATCAAAAAATTTCAGGCTCTGATGATA
TTTGTTCAGCTGCATTAAGTGCGGTGGCTAGAACGAAAAAAGTTCCAGCTGCGCCATCAGATGAAATTTATGAAAAATAT
AAATCACCAATTATTGACTTTGATATTCGATAA

Upstream 100 bases:

>100_bases
GCCTTATGAAGAAGTGATTAAGGCATTGAATTTACTTCATCTTGCAGGCATTAAATCTGTAGGTTTAATGACAAATCCCA
TTTAGCTAAGTAGGTAACAC

Downstream 100 bases:

>100_bases
TTCTTTAGAAAAATTTATTGTTAAATTTTAAAGGTAACAAAATGAAATTATTAAAACGTTTAGTGAGCGTATTCGCGATT
GTACTTGCTGTTGGAAGCAA

Product: cell envelope integrity inner membrane protein TolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MQNNRQKKGINAFAISILLHFILFGLLILSSLYHTVEIMGGGEGEGDVIGAVIVDTGTAAQEWGRIQQQKKGQSDKQKRP
EPVVEEKPPEPNQEEIKHQQEVQRQEELKRQQEIKKQQEQARQEALEKQKQAEEARAKQAAEAAKLKADAEAKRLAAAAK
QAEEEAKAKAAEIAAQKAKQEAEAKAKLEAEAKAKAVAEAKAKAEAEAKAKAAAEAKAKAEAEAKAKAEAKAKAEAKAKA
EAEAKAKAEAEAKAKAAAEAKAKADAEAKAATEAKRKADQASLDDFLNGGDIGGGSASKGGNTNKGGTQGSGAALGSGDG
GKVGDQYAGVIKKEIQRRFLKDPNFAGKVCRIKIQLGRDGTILGYQKISGSDDICSAALSAVARTKKVPAAPSDEIYEKY
KSPIIDFDIR

Sequences:

>Translated_410_residues
MQNNRQKKGINAFAISILLHFILFGLLILSSLYHTVEIMGGGEGEGDVIGAVIVDTGTAAQEWGRIQQQKKGQSDKQKRP
EPVVEEKPPEPNQEEIKHQQEVQRQEELKRQQEIKKQQEQARQEALEKQKQAEEARAKQAAEAAKLKADAEAKRLAAAAK
QAEEEAKAKAAEIAAQKAKQEAEAKAKLEAEAKAKAVAEAKAKAEAEAKAKAAAEAKAKAEAEAKAKAEAKAKAEAKAKA
EAEAKAKAEAEAKAKAAAEAKAKADAEAKAATEAKRKADQASLDDFLNGGDIGGGSASKGGNTNKGGTQGSGAALGSGDG
GKVGDQYAGVIKKEIQRRFLKDPNFAGKVCRIKIQLGRDGTILGYQKISGSDDICSAALSAVARTKKVPAAPSDEIYEKY
KSPIIDFDIR
>Mature_410_residues
MQNNRQKKGINAFAISILLHFILFGLLILSSLYHTVEIMGGGEGEGDVIGAVIVDTGTAAQEWGRIQQQKKGQSDKQKRP
EPVVEEKPPEPNQEEIKHQQEVQRQEELKRQQEIKKQQEQARQEALEKQKQAEEARAKQAAEAAKLKADAEAKRLAAAAK
QAEEEAKAKAAEIAAQKAKQEAEAKAKLEAEAKAKAVAEAKAKAEAEAKAKAAAEAKAKAEAEAKAKAEAKAKAEAKAKA
EAEAKAKAEAEAKAKAAAEAKAKADAEAKAATEAKRKADQASLDDFLNGGDIGGGSASKGGNTNKGGTQGSGAALGSGDG
GKVGDQYAGVIKKEIQRRFLKDPNFAGKVCRIKIQLGRDGTILGYQKISGSDDICSAALSAVARTKKVPAAPSDEIYEKY
KSPIIDFDIR

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG3064

COG function: function code M; Membrane protein involved in colicin uptake

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014161 [H]

Pfam domain/function: PF06519 TolA [H]

EC number: NA

Molecular weight: Translated: 43412; Mature: 43412

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure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CEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 8921895 [H]