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The map label for this gene is uxuR [H]

Identifier: 148827209

GI number: 148827209

Start: 508850

End: 509605

Strand: Direct

Name: uxuR [H]

Synonym: CGSHiGG_02770

Alternate gene names: 148827209

Gene position: 508850-509605 (Clockwise)

Preceding gene: 148827208

Following gene: 148827210

Centisome position: 26.96

GC content: 34.26

Gene sequence:

>756_bases
ATGATGCTCAGTGACTTACGCTCCTATAAAAAAATAGGAAATGAATTAAAAGAACAACTTGAAAATCACCAATATCAAAT
AGGCGATAAATTGCCGGCAGAACGTGATTTAGCTAATTATTTCAATGTGAGTCGAACCGTAATTAGAGAAGCGATCATTA
TGCTTGAATTAGAAAACCTTGTTGAAGTACGCAAAGGTTCTGGAGTGTATGTGATTGCATTGCCACAACGCACTGCAAGT
AATGATGAATTTTTAGATAAGGTTGATGTAGGCCCTTTTGAACTTTTACAAGCTCGCCAATTATTAGAAAGTAGTATGGC
TGAATTTGCTGCATTACAAGTGACAAGAGCAGATATTACTAAATTAAAAGACATTCTAGCAAGAGAGCGAAATACTCTTG
AACAAGGTGATGAAGATTATGTGGCAGATGAAGATTTTCATCGCACTATAGCAGAAATAACTCAAAATGAAGTTATCTTA
CAAATGCAAAAAGCATTATGGGATCTTCGTACCAATAGTCAAATGTGGAAAGGTTTGCATCTCCATATTCCAAATCAAAG
TTATCGTCACCTTTGGTTACAAGATCATGAAAATATTATTACAGCCCTGCAGAGAAAAGATCCTGCAATGGCAAAAAAAG
CAATGTGGCAACATTTAGAAAATGTTAAGCAAAAACTTTTTGAATTATCTGATGTAGATGATCCTAATTTTGATGGTTAT
CTATTTAATATGAGCCCAATTGTTGTTGATCGTTAA

Upstream 100 bases:

>100_bases
TTATCTAGTACAACCCAAAATAATAATATTGATAAATGTTTTTTACATATTGCATTTAACGTATAATTGGTAAACCAAAA
TACAAAGATAGGATTAAGAA

Downstream 100 bases:

>100_bases
AAAACTATAGGAGTTAAAAATGGAACAAGCATGGCGTTGGTATGGACCAAAAGATCCTGTTTCTTTATCTGATATTCGTC
AAGCAGGTGCAACTGGTATA

Product: D-mannonate oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MMLSDLRSYKKIGNELKEQLENHQYQIGDKLPAERDLANYFNVSRTVIREAIIMLELENLVEVRKGSGVYVIALPQRTAS
NDEFLDKVDVGPFELLQARQLLESSMAEFAALQVTRADITKLKDILARERNTLEQGDEDYVADEDFHRTIAEITQNEVIL
QMQKALWDLRTNSQMWKGLHLHIPNQSYRHLWLQDHENIITALQRKDPAMAKKAMWQHLENVKQKLFELSDVDDPNFDGY
LFNMSPIVVDR

Sequences:

>Translated_251_residues
MMLSDLRSYKKIGNELKEQLENHQYQIGDKLPAERDLANYFNVSRTVIREAIIMLELENLVEVRKGSGVYVIALPQRTAS
NDEFLDKVDVGPFELLQARQLLESSMAEFAALQVTRADITKLKDILARERNTLEQGDEDYVADEDFHRTIAEITQNEVIL
QMQKALWDLRTNSQMWKGLHLHIPNQSYRHLWLQDHENIITALQRKDPAMAKKAMWQHLENVKQKLFELSDVDDPNFDGY
LFNMSPIVVDR
>Mature_251_residues
MMLSDLRSYKKIGNELKEQLENHQYQIGDKLPAERDLANYFNVSRTVIREAIIMLELENLVEVRKGSGVYVIALPQRTAS
NDEFLDKVDVGPFELLQARQLLESSMAEFAALQVTRADITKLKDILARERNTLEQGDEDYVADEDFHRTIAEITQNEVIL
QMQKALWDLRTNSQMWKGLHLHIPNQSYRHLWLQDHENIITALQRKDPAMAKKAMWQHLENVKQKLFELSDVDDPNFDGY
LFNMSPIVVDR

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=245, Percent_Identity=47.7551020408163, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI87082208, Length=244, Percent_Identity=49.1803278688525, Blast_Score=211, Evalue=3e-56,
Organism=Escherichia coli, GI1789621, Length=219, Percent_Identity=30.1369863013699, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1790032, Length=233, Percent_Identity=29.6137339055794, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787821, Length=201, Percent_Identity=25.3731343283582, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789353, Length=212, Percent_Identity=28.3018867924528, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786303, Length=241, Percent_Identity=26.9709543568465, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI48994955, Length=227, Percent_Identity=24.6696035242291, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 29254; Mature: 29254

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLSDLRSYKKIGNELKEQLENHQYQIGDKLPAERDLANYFNVSRTVIREAIIMLELENL
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEVRKGSGVYVIALPQRTASNDEFLDKVDVGPFELLQARQLLESSMAEFAALQVTRADIT
HHHHCCCCEEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLKDILARERNTLEQGDEDYVADEDFHRTIAEITQNEVILQMQKALWDLRTNSQMWKGLH
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEE
LHIPNQSYRHLWLQDHENIITALQRKDPAMAKKAMWQHLENVKQKLFELSDVDDPNFDGY
EECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
LFNMSPIVVDR
EEECCCEEECC
>Mature Secondary Structure
MMLSDLRSYKKIGNELKEQLENHQYQIGDKLPAERDLANYFNVSRTVIREAIIMLELENL
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEVRKGSGVYVIALPQRTASNDEFLDKVDVGPFELLQARQLLESSMAEFAALQVTRADIT
HHHHCCCCEEEEEECCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLKDILARERNTLEQGDEDYVADEDFHRTIAEITQNEVILQMQKALWDLRTNSQMWKGLH
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEE
LHIPNQSYRHLWLQDHENIITALQRKDPAMAKKAMWQHLENVKQKLFELSDVDDPNFDGY
EECCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
LFNMSPIVVDR
EEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]