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The map label for this gene is entD [C]

Identifier: 148823982

GI number: 148823982

Start: 3115212

End: 3115895

Strand: Reverse

Name: entD [C]

Synonym: TBFG_12807

Alternate gene names: 148823982

Gene position: 3115895-3115212 (Counterclockwise)

Preceding gene: 148823983

Following gene: 148823981

Centisome position: 70.42

GC content: 66.37

Gene sequence:

>684_bases
ATGACGGTAGGCACGCTGGTGGCGTCGGTGTTGCCGGCGACCGTGTTCGAGGATTTGGCGTATGCCGAGTTGTACTCCGA
CCCACCCGGTCTCACCCCGCTGCCCGAGGAGGCGCCGTTGATCGCACGATCGGTTGCCAAGCGGCGCAACGAATTCATCA
CCGTGCGTCACTGCGCCCGCATCGCGCTGGACCAGCTCGGTGTGCCGCCGGCGCCGATCCTCAAGGGCGACAAGGGCGAA
CCGTGCTGGCCCGACGGCGTGGTCGGTAGCCTCACCCACTGCGCCGGTTACCGCGGCGCGGTTGTCGGACGCAGGGATGC
GGTGCGTTCCGTGGGCATCGACGCCGAACCGCACGACGTGTTGCCCAATGGTGTGCTGGATGCGATCAGCCTGCCGGCCG
AGCGCGCCGACATGCCCCGCACCATGCCAGCGGCGTTGCATTGGGATCGAATCCTGTTCTGCGCCAAGGAAGCAACGTAC
AAGGCGTGGTTTCCGCTGACCAAGAGGTGGCTGGGTTTCGAGGACGCGCACATCACGTTCGAAACCGATAGCACCGGCTG
GACGGGTCGCTTCGTCTCCCGTATCCTCATCGACGGGTCCACCCTGTCGGGTCCGCCGCTGACAACGCTGCGGGGACGCT
GGTCGGTTGAGCGCGGACTGGTGCTGACCGCGATCGTGCTATGA

Upstream 100 bases:

>100_bases
CCGGCTACCTCAACGACTTCGGCGGTCACTTCGTGATCACGCCCGAGATGCGAACCCAGGCCGCCCAGTTCCGGGAACGA
TTGCGGCAACGGCAGTCTCG

Downstream 100 bases:

>100_bases
GCGCAACCGGCCCCGGAATCGTGGTTATCGACAAGCCCGCGGGAATGACCAGCCATGACGTGGTGGGGCGGTGCCGCCGC
ATCTTCGCCACCCGGCGGGT

Product: hypothetical protein

Products: pyrophosphate; AMP; enterobactin; aryl carrier protein/isochorismatase; 3',5'-ADP; serine activating enzyme + [C]

Alternate protein names: Phosphopantetheinyl Transferase; Phosphopantetheinyl Transferase PptA; Sfp-Type Phosphopantetheinyl Transferase; Holo-[Acyl-Carrier-Protein] Synthase; EntD Family Protein; Phosphopantetheinyl Transferase PptII; Transferase; 4-Phosphopantetheinyl Transferase Superfamily

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MTVGTLVASVLPATVFEDLAYAELYSDPPGLTPLPEEAPLIARSVAKRRNEFITVRHCARIALDQLGVPPAPILKGDKGE
PCWPDGVVGSLTHCAGYRGAVVGRRDAVRSVGIDAEPHDVLPNGVLDAISLPAERADMPRTMPAALHWDRILFCAKEATY
KAWFPLTKRWLGFEDAHITFETDSTGWTGRFVSRILIDGSTLSGPPLTTLRGRWSVERGLVLTAIVL

Sequences:

>Translated_227_residues
MTVGTLVASVLPATVFEDLAYAELYSDPPGLTPLPEEAPLIARSVAKRRNEFITVRHCARIALDQLGVPPAPILKGDKGE
PCWPDGVVGSLTHCAGYRGAVVGRRDAVRSVGIDAEPHDVLPNGVLDAISLPAERADMPRTMPAALHWDRILFCAKEATY
KAWFPLTKRWLGFEDAHITFETDSTGWTGRFVSRILIDGSTLSGPPLTTLRGRWSVERGLVLTAIVL
>Mature_226_residues
TVGTLVASVLPATVFEDLAYAELYSDPPGLTPLPEEAPLIARSVAKRRNEFITVRHCARIALDQLGVPPAPILKGDKGEP
CWPDGVVGSLTHCAGYRGAVVGRRDAVRSVGIDAEPHDVLPNGVLDAISLPAERADMPRTMPAALHWDRILFCAKEATYK
AWFPLTKRWLGFEDAHITFETDSTGWTGRFVSRILIDGSTLSGPPLTTLRGRWSVERGLVLTAIVL

Specific function: Catalyzes The Transfer Of The 4'-Phosphopantetheine Moiety From Coenzyme A To Apo-Domains Of Both Entb (An Arcp Domain) And Entf (A Pcp Domain). Plays An Essential Role In The Assembly Of The Enterobactin. [C]

COG id: COG2977

COG function: function code Q; Phosphopantetheinyl transferase component of siderophore synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.8.- [C]

Molecular weight: Translated: 24677; Mature: 24545

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVGTLVASVLPATVFEDLAYAELYSDPPGLTPLPEEAPLIARSVAKRRNEFITVRHCAR
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCEEHHHHHHH
IALDQLGVPPAPILKGDKGEPCWPDGVVGSLTHCAGYRGAVVGRRDAVRSVGIDAEPHDV
HHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCC
LPNGVLDAISLPAERADMPRTMPAALHWDRILFCAKEATYKAWFPLTKRWLGFEDAHITF
CCCHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEE
ETDSTGWTGRFVSRILIDGSTLSGPPLTTLRGRWSVERGLVLTAIVL
ECCCCCCHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCEEEEEEEC
>Mature Secondary Structure 
TVGTLVASVLPATVFEDLAYAELYSDPPGLTPLPEEAPLIARSVAKRRNEFITVRHCAR
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCEEHHHHHHH
IALDQLGVPPAPILKGDKGEPCWPDGVVGSLTHCAGYRGAVVGRRDAVRSVGIDAEPHDV
HHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHCCCCCCCCCC
LPNGVLDAISLPAERADMPRTMPAALHWDRILFCAKEATYKAWFPLTKRWLGFEDAHITF
CCCHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEE
ETDSTGWTGRFVSRILIDGSTLSGPPLTTLRGRWSVERGLVLTAIVL
ECCCCCCHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate; Coenzyme A; apo-EntB; apo-serine activating enzyme [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin Coenzyme A + apo-EntB = aryl carrier protein/isochorismatase + 3',5'-ADP Coenzyme A + apo-serine activating enzyme = 3',5'-ADP + serine activating enzyme [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA