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The map label for this gene is glfT

Identifier: 148663676

GI number: 148663676

Start: 4278812

End: 4280725

Strand: Reverse

Name: glfT

Synonym: MRA_3848

Alternate gene names: 148663676

Gene position: 4280725-4278812 (Counterclockwise)

Preceding gene: 148663677

Following gene: 148663675

Centisome position: 96.85

GC content: 64.52

Gene sequence:

>1914_bases
ATGAGTGAACTCGCCGCGAGCCTGCTGTCTCGGGTCATCCTGCCGCGCCCAGGTGAACCCCTTGACGTGCGCAAGCTGTA
CCTCGAGGAGTCAACGACCAACGCCCGGCGCGCGCATGCGCCAACCCGGACCTCGCTACAGATTGGCGCGGAGTCCGAGG
TGTCGTTCGCCACCTACTTCAACGCTTTCCCGGCTAGCTATTGGCGACGTTGGACGACGTGCAAATCGGTGGTGTTGCGC
GTGCAGGTGACCGGCGCCGGGCGGGTAGACGTCTACCGGACCAAGGCCACCGGTGCCCGGATCTTCGTTGAGGGCCACGA
CTTCACCGGCACCGAGGATCAGCCAGCCGCCGTGGAGACCGAAGTGGTGCTGCAGCCTTTCGAAGACGGCGGGTGGGTCT
GGTTCGACATCACCACCGACACCGCGGTCACCCTGCACAGTGGTGGCTGGTATGCCACCAGCCCCGCTCCGGGGACGGCC
AACATCGCGGTCGGCATCCCGACGTTCAACCGCCCCGCAGACTGCGTCAACGCGCTGCGAGAACTCACCGCCGATCCGCT
GGTGGACCAGGTGATCGGGGCGGTGATCGTGCCTGATCAGGGTGAGCGCAAGGTGCGCGACCACCCGGATTTCCCCGCCG
CGGCTGCGAGATTGGGTAGTCGGCTCTCCATCCACGACCAGCCCAACCTGGGCGGTTCCGGCGGCTACAGCCGGGTGATG
TATGAGGCACTGAAAAACACCGACTGTCAGCAGATCCTATTCATGGACGACGACATCCGCCTCGAGCCGGACTCGATTCT
GCGGGTGCTGGCCATGCACCGGTTCGCCAAGGCGCCGATGCTGGTGGGTGGTCAGATGCTCAACCTGCAGGAGCCGTCGC
ACCTGCACATCATGGGCGAAGTCGTAGACCGGTCGATATTCATGTGGACCGCCGCGCCGCATGCCGAGTATGACCACGAC
TTCGCCGAATACCCGTTGAACGACAACAACTCCCGTAGCAAGTTGCTGCACCGGCGTATCGATGTCGACTACAACGGCTG
GTGGACGTGCATGATCCCACGCCAGGTCGCCGAAGAGCTAGGACAGCCGCTGCCGTTGTTCATCAAATGGGACGACGCCG
ATTACGGCCTGCGGGCCGCCGAGCACGGGTATCCGACCGTCACGCTGCCCGGTGCGGCGATCTGGCACATGGCCTGGAGC
GATAAGGATGACGCCATCGACTGGCAGGCCTATTTCCATCTGCGCAACCGGCTGGTGGTGGCCGCCATGCACTGGGACGG
CCCAAAGGCGCAAGTCATCGGCCTGGTCCGCAGCCATCTCAAGGCAACCCTGAAACACCTTGCCTGCCTGGAATATTCGA
CGGTGGCAATCCAGAACAAGGCCATCGACGACTTTCTCGCCGGCCCCGAGCACATCTTTTCGATCCTGGAATCGGCGCTG
CCGCAAGTGCACCGCATCCGCAAGAGCTATCCGGACGCGGTGGTGCTGCCGGCGGCCAGTGAGTTGCCGCCGCCGTTGCA
CAAGAACAAGGCAATGAAGCCGCCGGTGAACCCGTTGGTCATCGGCTACCGGCTGGCCCGCGGGATCATGCACAACCTGA
CCGCCGCCAACCCCCAACACCACCGTCGCCCGGAGTTCAACGTTCCGACCCAGGATGCGCGCTGGTTCCTGCTGTGCACT
GTCGACGGGGCCACCGTCACCACGGCCGACGGATGCGGCGTGGTCTACCGGCAGCGCGACCGGGCCAAGATGTTCGCGTT
GCTGTGGCAGTCGTTGCGCCGTCAGCGCCAGTTGCTGAAACGGTTCGAGGAGATGCGCCGGATTTATCGCGACGCGTTGC
CGACGCTGTCCAGCAAGCAGAAGTGGGAGACGGCGCTGCTGCCGGCGGCAAACCAAGAGCCCGAGCATGGCTGA

Upstream 100 bases:

>100_bases
ATCTGGATATGCATATGGCCATTGCCAGCGCCTTGAACATGTACGACAACGTCCTCGCGCCGCATCTGCGCGACGGCGTC
CCACTGCTTCAGGACGGCGC

Downstream 100 bases:

>100_bases
ACGGGCGCCACGCGGCGAAGTCGCCGTGATGGTGGCCGTGCAGTCGGCGCTGGTCGACCGTCCGGGGATGCTGGCCACTG
CGCGCGGACTCTCCCACTTC

Product: bifunctional udp-galactofuranosyl transferase

Products: NA

Alternate protein names: GalTr; Beta-D-(1-5)galactofuranosyltransferase; Beta-D-(1-6)galactofuranosyltransferase; UDP-Galf:alpha-3-L-rhamnosyl-alpha-D-GlcNAc-pyrophosphate polyprenol, UDP-galactofuranosyl transferase

Number of amino acids: Translated: 637; Mature: 636

Protein sequence:

>637_residues
MSELAASLLSRVILPRPGEPLDVRKLYLEESTTNARRAHAPTRTSLQIGAESEVSFATYFNAFPASYWRRWTTCKSVVLR
VQVTGAGRVDVYRTKATGARIFVEGHDFTGTEDQPAAVETEVVLQPFEDGGWVWFDITTDTAVTLHSGGWYATSPAPGTA
NIAVGIPTFNRPADCVNALRELTADPLVDQVIGAVIVPDQGERKVRDHPDFPAAAARLGSRLSIHDQPNLGGSGGYSRVM
YEALKNTDCQQILFMDDDIRLEPDSILRVLAMHRFAKAPMLVGGQMLNLQEPSHLHIMGEVVDRSIFMWTAAPHAEYDHD
FAEYPLNDNNSRSKLLHRRIDVDYNGWWTCMIPRQVAEELGQPLPLFIKWDDADYGLRAAEHGYPTVTLPGAAIWHMAWS
DKDDAIDWQAYFHLRNRLVVAAMHWDGPKAQVIGLVRSHLKATLKHLACLEYSTVAIQNKAIDDFLAGPEHIFSILESAL
PQVHRIRKSYPDAVVLPAASELPPPLHKNKAMKPPVNPLVIGYRLARGIMHNLTAANPQHHRRPEFNVPTQDARWFLLCT
VDGATVTTADGCGVVYRQRDRAKMFALLWQSLRRQRQLLKRFEEMRRIYRDALPTLSSKQKWETALLPAANQEPEHG

Sequences:

>Translated_637_residues
MSELAASLLSRVILPRPGEPLDVRKLYLEESTTNARRAHAPTRTSLQIGAESEVSFATYFNAFPASYWRRWTTCKSVVLR
VQVTGAGRVDVYRTKATGARIFVEGHDFTGTEDQPAAVETEVVLQPFEDGGWVWFDITTDTAVTLHSGGWYATSPAPGTA
NIAVGIPTFNRPADCVNALRELTADPLVDQVIGAVIVPDQGERKVRDHPDFPAAAARLGSRLSIHDQPNLGGSGGYSRVM
YEALKNTDCQQILFMDDDIRLEPDSILRVLAMHRFAKAPMLVGGQMLNLQEPSHLHIMGEVVDRSIFMWTAAPHAEYDHD
FAEYPLNDNNSRSKLLHRRIDVDYNGWWTCMIPRQVAEELGQPLPLFIKWDDADYGLRAAEHGYPTVTLPGAAIWHMAWS
DKDDAIDWQAYFHLRNRLVVAAMHWDGPKAQVIGLVRSHLKATLKHLACLEYSTVAIQNKAIDDFLAGPEHIFSILESAL
PQVHRIRKSYPDAVVLPAASELPPPLHKNKAMKPPVNPLVIGYRLARGIMHNLTAANPQHHRRPEFNVPTQDARWFLLCT
VDGATVTTADGCGVVYRQRDRAKMFALLWQSLRRQRQLLKRFEEMRRIYRDALPTLSSKQKWETALLPAANQEPEHG
>Mature_636_residues
SELAASLLSRVILPRPGEPLDVRKLYLEESTTNARRAHAPTRTSLQIGAESEVSFATYFNAFPASYWRRWTTCKSVVLRV
QVTGAGRVDVYRTKATGARIFVEGHDFTGTEDQPAAVETEVVLQPFEDGGWVWFDITTDTAVTLHSGGWYATSPAPGTAN
IAVGIPTFNRPADCVNALRELTADPLVDQVIGAVIVPDQGERKVRDHPDFPAAAARLGSRLSIHDQPNLGGSGGYSRVMY
EALKNTDCQQILFMDDDIRLEPDSILRVLAMHRFAKAPMLVGGQMLNLQEPSHLHIMGEVVDRSIFMWTAAPHAEYDHDF
AEYPLNDNNSRSKLLHRRIDVDYNGWWTCMIPRQVAEELGQPLPLFIKWDDADYGLRAAEHGYPTVTLPGAAIWHMAWSD
KDDAIDWQAYFHLRNRLVVAAMHWDGPKAQVIGLVRSHLKATLKHLACLEYSTVAIQNKAIDDFLAGPEHIFSILESALP
QVHRIRKSYPDAVVLPAASELPPPLHKNKAMKPPVNPLVIGYRLARGIMHNLTAANPQHHRRPEFNVPTQDARWFLLCTV
DGATVTTADGCGVVYRQRDRAKMFALLWQSLRRQRQLLKRFEEMRRIYRDALPTLSSKQKWETALLPAANQEPEHG

Specific function: Involved in the polymerization of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component the mycobacteria cell wall, through successively beta-D-(1->5) and beta-D-(1->6)- galactofuranosyltransfer

COG id: COG1216

COG function: function code R; Predicted glycosyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLFT2_MYCTU (O53585)

Other databases:

- EMBL:   BX842584
- PIR:   D70888
- RefSeq:   NP_218325.1
- ProteinModelPortal:   O53585
- EnsemblBacteria:   EBMYCT00000003922
- GeneID:   886136
- GenomeReviews:   AL123456_GR
- KEGG:   mtu:Rv3808c
- TubercuList:   Rv3808c
- GeneTree:   EBGT00050000017089
- HOGENOM:   HBG657765
- OMA:   LCLEYST
- ProtClustDB:   CLSK872249
- BioCyc:   MetaCyc:MONOMER-15256
- GO:   GO:0005829
- GO:   GO:0040007

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 71507; Mature: 71376

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELAASLLSRVILPRPGEPLDVRKLYLEESTTNARRAHAPTRTSLQIGAESEVSFATYF
CHHHHHHHHHHHHCCCCCCCCCHHHEEECCCCCCCHHCCCCCCCEEEECCCCCCCHHHHH
NAFPASYWRRWTTCKSVVLRVQVTGAGRVDVYRTKATGARIFVEGHDFTGTEDQPAAVET
HHCCHHHHHHHHHHEEEEEEEEECCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCEEE
EVVLQPFEDGGWVWFDITTDTAVTLHSGGWYATSPAPGTANIAVGIPTFNRPADCVNALR
EEEEEECCCCCEEEEEEECCCEEEEECCCEEECCCCCCCCEEEEECCCCCCHHHHHHHHH
ELTADPLVDQVIGAVIVPDQGERKVRDHPDFPAAAARLGSRLSIHDQPNLGGSGGYSRVM
HHHCCHHHHHHHCEEECCCCCCCCCCCCCCCCHHHHHCCCEEEECCCCCCCCCCCHHHHH
YEALKNTDCQQILFMDDDIRLEPDSILRVLAMHRFAKAPMLVGGQMLNLQEPSHLHIMGE
HHHHCCCCCEEEEEECCCCEECHHHHHHHHHHHHHHCCCHHCCCEEECCCCCCCEEEEHH
VVDRSIFMWTAAPHAEYDHDFAEYPLNDNNSRSKLLHRRIDVDYNGWWTCMIPRQVAEEL
HHCCEEEEEECCCCCCCCCCHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEECCHHHHHHC
GQPLPLFIKWDDADYGLRAAEHGYPTVTLPGAAIWHMAWSDKDDAIDWQAYFHLRNRLVV
CCCCEEEEEECCCCCCCCHHCCCCCEEEECCCEEEEEEECCCCCCCHHHHHHHHHCCEEE
AAMHWDGPKAQVIGLVRSHLKATLKHLACLEYSTVAIQNKAIDDFLAGPEHIFSILESAL
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECHHHHHHHCCHHHHHHHHHHHH
PQVHRIRKSYPDAVVLPAASELPPPLHKNKAMKPPVNPLVIGYRLARGIMHNLTAANPQH
HHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHH
HRRPEFNVPTQDARWFLLCTVDGATVTTADGCGVVYRQRDRAKMFALLWQSLRRQRQLLK
CCCCCCCCCCCCCCEEEEEEECCCEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHH
RFEEMRRIYRDALPTLSSKQKWETALLPAANQEPEHG
HHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SELAASLLSRVILPRPGEPLDVRKLYLEESTTNARRAHAPTRTSLQIGAESEVSFATYF
HHHHHHHHHHHHCCCCCCCCCHHHEEECCCCCCCHHCCCCCCCEEEECCCCCCCHHHHH
NAFPASYWRRWTTCKSVVLRVQVTGAGRVDVYRTKATGARIFVEGHDFTGTEDQPAAVET
HHCCHHHHHHHHHHEEEEEEEEECCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCEEE
EVVLQPFEDGGWVWFDITTDTAVTLHSGGWYATSPAPGTANIAVGIPTFNRPADCVNALR
EEEEEECCCCCEEEEEEECCCEEEEECCCEEECCCCCCCCEEEEECCCCCCHHHHHHHHH
ELTADPLVDQVIGAVIVPDQGERKVRDHPDFPAAAARLGSRLSIHDQPNLGGSGGYSRVM
HHHCCHHHHHHHCEEECCCCCCCCCCCCCCCCHHHHHCCCEEEECCCCCCCCCCCHHHHH
YEALKNTDCQQILFMDDDIRLEPDSILRVLAMHRFAKAPMLVGGQMLNLQEPSHLHIMGE
HHHHCCCCCEEEEEECCCCEECHHHHHHHHHHHHHHCCCHHCCCEEECCCCCCCEEEEHH
VVDRSIFMWTAAPHAEYDHDFAEYPLNDNNSRSKLLHRRIDVDYNGWWTCMIPRQVAEEL
HHCCEEEEEECCCCCCCCCCHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEECCHHHHHHC
GQPLPLFIKWDDADYGLRAAEHGYPTVTLPGAAIWHMAWSDKDDAIDWQAYFHLRNRLVV
CCCCEEEEEECCCCCCCCHHCCCCCEEEECCCEEEEEEECCCCCCCHHHHHHHHHCCEEE
AAMHWDGPKAQVIGLVRSHLKATLKHLACLEYSTVAIQNKAIDDFLAGPEHIFSILESAL
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECHHHHHHHCCHHHHHHHHHHHH
PQVHRIRKSYPDAVVLPAASELPPPLHKNKAMKPPVNPLVIGYRLARGIMHNLTAANPQH
HHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHH
HRRPEFNVPTQDARWFLLCTVDGATVTTADGCGVVYRQRDRAKMFALLWQSLRRQRQLLK
CCCCCCCCCCCCCCEEEEEEECCCEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHH
RFEEMRRIYRDALPTLSSKQKWETALLPAANQEPEHG
HHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230