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The map label for this gene is ppe20

Identifier: 148661178

GI number: 148661178

Start: 1563079

End: 1564698

Strand: Direct

Name: ppe20

Synonym: MRA_1396

Alternate gene names: 148661178

Gene position: 1563079-1564698 (Clockwise)

Preceding gene: 148661177

Following gene: 148661179

Centisome position: 35.36

GC content: 65.49

Gene sequence:

>1620_bases
ATGACCGAGCCGTGGATAGCCTTCCCTCCCGAGGTGCACTCGGCGATGCTGAACTACGGTGCGGGCGTTGGGCCGATGTT
GATCTCCGCCACGCAGAATGGGGAGCTCAGCGCCCAATACGCAGAAGCGGCATCAGAGGTCGAGGAATTGTTGGGGGTGG
TGGCCTCCGAGGGATGGCAGGGGCAAGCCGCCGAGGCGTTTGTCGCCGCGTACATGCCGTTTCTGGCGTGGCTGATCCAA
GCCAGCGCCGACTGCGTGGAAATGGCCGCCCAGCAACACGTCGTCATCGAGGCCTACACTGCCGCGGTAGAGCTGATGCC
TACTCAGGTCGAACTGGCCGCCAACCAAATCAAGCTCGCGGTGTTGGTAGCGACCAATTTCTTTGGCATCAACACCATTC
CCATTGCGATCAATGAGGCCGAGTACGTGGAGATGTGGGTTCGGGCCGCCACCACGATGGCGACCTATTCAACAGTCTCC
AGATCGGCGCTCTCCGCGATGCCGCACACCAGCCCCCCGCCGCTGATCCTGAAATCCGATGAACTGCTCCCCGACACCGG
GGAGGACTCCGATGAAGACGGCCACAACCATGGCGGTCACAGTCATGGCGGTCACGCCAGGATGATCGATAACTTCTTTG
CCGAAATCCTGCGTGGCGTCAGCGCGGGCCGCATTGTTTGGGACCCCGTCAACGGCACCCTCAACGGACTCGACTACGAC
GATTACGTCTACCCCGGTCACGCGATCTGGTGGCTGGCTCGAGGCCTCGAGTTTTTTCAGGATGGTGAACAATTTGGCGA
ACTGTTGTTCACCAATCCGACTGGGGCTTTTCAGTTCCTCCTCTACGTCGTTGTGGTGGATTTGCCGACGCACATAGCCC
AGATCGCTACCTGGCTGGGCCAGTACCCGCAGTTGCTGTCGGCTGCCCTCACTGGCGTCATCGCCCACCTGGGAGCAATA
ACTGGTTTGGCGGGCCTATCCGGCCTGAGCGCCATTCCGTCTGCTGCGATACCCGCCGTTGTACCGGAGCTGACACCCGT
CGCGGCCGCGCCGCCTATGTTGGCGGTCGCCGGGGTGGGCCCTGCAGTCGCCGCGCCGGGCATGCTCCCCGCCTCAGCAC
CCGCACCGGCGGCAGCGGCCGGCGCCACCGCAGCCGGCCCGACGCCGCCGGCGACTGGTTTCGGAGGCTTCCCGCCCTAC
CTGGTCGGCGGTGGCGGCCCAGGAATAGGGTTCGGCTCGGGACAGTCGGCCCACGCCAAGGCCGCGGCGTCCGATTCCGC
TGCAGCCGAGTCGGCGGCCCAGGCCTCGGCGCGTGCGCAGGCGCGTGCTGCACGGCGGGGCCGCTCGGCGGCGAAGGCAC
GTGGCCATCGTGACGAATTCGTCACGATGGACATGGGTTTCGACGCGGCAGCTCCGGCCCCAGAGCACCAGCCGGGTGCC
CGGGCGTCCGACTGTGGTGCGGGACCTATCGGATTTGCTGGCACGGTGCGCAAAGAGGCGGTCGTGAAAGCGGCGGGGTT
GACCACGCTGGCCGGTGACGACTTCGGCGGCGGCCCAACGATGCCGATGATGCCCGGCACCTGGACCCATGATCAGGGCG
TGTTCGACGAGCATCGCTGA

Upstream 100 bases:

>100_bases
TTGAGGAGCTCGGCCGCTCGGGGGTCGGGGTGGCCGAATCGGGTGCCAGTTATGCCGCTAGGGATGCGCTGGCGGCGGCG
TCGTATCTCAGCGGTGGGCT

Downstream 100 bases:

>100_bases
TAGCTGACTGGGCAGTGGCTGGCAAACAGCTGAGAGAGCACTCGAGAGCTATCGTCAGGGCAATGTCCGATGATGCTGAG
CACCCGCGTTTGGGGCACTA

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 538

Protein sequence:

>539_residues
MTEPWIAFPPEVHSAMLNYGAGVGPMLISATQNGELSAQYAEAASEVEELLGVVASEGWQGQAAEAFVAAYMPFLAWLIQ
ASADCVEMAAQQHVVIEAYTAAVELMPTQVELAANQIKLAVLVATNFFGINTIPIAINEAEYVEMWVRAATTMATYSTVS
RSALSAMPHTSPPPLILKSDELLPDTGEDSDEDGHNHGGHSHGGHARMIDNFFAEILRGVSAGRIVWDPVNGTLNGLDYD
DYVYPGHAIWWLARGLEFFQDGEQFGELLFTNPTGAFQFLLYVVVVDLPTHIAQIATWLGQYPQLLSAALTGVIAHLGAI
TGLAGLSGLSAIPSAAIPAVVPELTPVAAAPPMLAVAGVGPAVAAPGMLPASAPAPAAAAGATAAGPTPPATGFGGFPPY
LVGGGGPGIGFGSGQSAHAKAAASDSAAAESAAQASARAQARAARRGRSAAKARGHRDEFVTMDMGFDAAAPAPEHQPGA
RASDCGAGPIGFAGTVRKEAVVKAAGLTTLAGDDFGGGPTMPMMPGTWTHDQGVFDEHR

Sequences:

>Translated_539_residues
MTEPWIAFPPEVHSAMLNYGAGVGPMLISATQNGELSAQYAEAASEVEELLGVVASEGWQGQAAEAFVAAYMPFLAWLIQ
ASADCVEMAAQQHVVIEAYTAAVELMPTQVELAANQIKLAVLVATNFFGINTIPIAINEAEYVEMWVRAATTMATYSTVS
RSALSAMPHTSPPPLILKSDELLPDTGEDSDEDGHNHGGHSHGGHARMIDNFFAEILRGVSAGRIVWDPVNGTLNGLDYD
DYVYPGHAIWWLARGLEFFQDGEQFGELLFTNPTGAFQFLLYVVVVDLPTHIAQIATWLGQYPQLLSAALTGVIAHLGAI
TGLAGLSGLSAIPSAAIPAVVPELTPVAAAPPMLAVAGVGPAVAAPGMLPASAPAPAAAAGATAAGPTPPATGFGGFPPY
LVGGGGPGIGFGSGQSAHAKAAASDSAAAESAAQASARAQARAARRGRSAAKARGHRDEFVTMDMGFDAAAPAPEHQPGA
RASDCGAGPIGFAGTVRKEAVVKAAGLTTLAGDDFGGGPTMPMMPGTWTHDQGVFDEHR
>Mature_538_residues
TEPWIAFPPEVHSAMLNYGAGVGPMLISATQNGELSAQYAEAASEVEELLGVVASEGWQGQAAEAFVAAYMPFLAWLIQA
SADCVEMAAQQHVVIEAYTAAVELMPTQVELAANQIKLAVLVATNFFGINTIPIAINEAEYVEMWVRAATTMATYSTVSR
SALSAMPHTSPPPLILKSDELLPDTGEDSDEDGHNHGGHSHGGHARMIDNFFAEILRGVSAGRIVWDPVNGTLNGLDYDD
YVYPGHAIWWLARGLEFFQDGEQFGELLFTNPTGAFQFLLYVVVVDLPTHIAQIATWLGQYPQLLSAALTGVIAHLGAIT
GLAGLSGLSAIPSAAIPAVVPELTPVAAAPPMLAVAGVGPAVAAPGMLPASAPAPAAAAGATAAGPTPPATGFGGFPPYL
VGGGGPGIGFGSGQSAHAKAAASDSAAAESAAQASARAQARAARRGRSAAKARGHRDEFVTMDMGFDAAAPAPEHQPGAR
ASDCGAGPIGFAGTVRKEAVVKAAGLTTLAGDDFGGGPTMPMMPGTWTHDQGVFDEHR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPE20_MYCTU (Q7D8H6)

Other databases:

- EMBL:   BX842576
- EMBL:   AE000516
- PIR:   A70899
- RefSeq:   NP_335882.1
- RefSeq:   YP_177806.1
- ProteinModelPortal:   Q7D8H6
- SMR:   Q7D8H6
- EnsemblBacteria:   EBMYCT00000002240
- EnsemblBacteria:   EBMYCT00000072934
- GeneID:   886784
- GeneID:   923015
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1431
- KEGG:   mtu:Rv1387
- TIGR:   MT1431
- TubercuList:   Rv1387
- GeneTree:   EBGT00050000014875
- HOGENOM:   HBG572308
- ProtClustDB:   CLSK799358
- InterPro:   IPR000030

Pfam domain/function: PF00823 PPE

EC number: NA

Molecular weight: Translated: 55404; Mature: 55273

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPWIAFPPEVHSAMLNYGAGVGPMLISATQNGELSAQYAEAASEVEELLGVVASEGWQ
CCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
GQAAEAFVAAYMPFLAWLIQASADCVEMAAQQHVVIEAYTAAVELMPTQVELAANQIKLA
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEEHHHHHHHCCHHHHHHHHHEEEE
VLVATNFFGINTIPIAINEAEYVEMWVRAATTMATYSTVSRSALSAMPHTSPPPLILKSD
EEEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECC
ELLPDTGEDSDEDGHNHGGHSHGGHARMIDNFFAEILRGVSAGRIVWDPVNGTLNGLDYD
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCC
DYVYPGHAIWWLARGLEFFQDGEQFGELLFTNPTGAFQFLLYVVVVDLPTHIAQIATWLG
CEECCCHHHHHHHHHHHHHHCHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QYPQLLSAALTGVIAHLGAITGLAGLSGLSAIPSAAIPAVVPELTPVAAAPPMLAVAGVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCEEEECCC
PAVAAPGMLPASAPAPAAAAGATAAGPTPPATGFGGFPPYLVGGGGPGIGFGSGQSAHAK
HHHHCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHH
AAASDSAAAESAAQASARAQARAARRGRSAAKARGHRDEFVTMDMGFDAAAPAPEHQPGA
HHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCC
RASDCGAGPIGFAGTVRKEAVVKAAGLTTLAGDDFGGGPTMPMMPGTWTHDQGVFDEHR
CCCCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEPWIAFPPEVHSAMLNYGAGVGPMLISATQNGELSAQYAEAASEVEELLGVVASEGWQ
CCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
GQAAEAFVAAYMPFLAWLIQASADCVEMAAQQHVVIEAYTAAVELMPTQVELAANQIKLA
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEEHHHHHHHCCHHHHHHHHHEEEE
VLVATNFFGINTIPIAINEAEYVEMWVRAATTMATYSTVSRSALSAMPHTSPPPLILKSD
EEEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECC
ELLPDTGEDSDEDGHNHGGHSHGGHARMIDNFFAEILRGVSAGRIVWDPVNGTLNGLDYD
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCC
DYVYPGHAIWWLARGLEFFQDGEQFGELLFTNPTGAFQFLLYVVVVDLPTHIAQIATWLG
CEECCCHHHHHHHHHHHHHHCHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QYPQLLSAALTGVIAHLGAITGLAGLSGLSAIPSAAIPAVVPELTPVAAAPPMLAVAGVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCEEEECCC
PAVAAPGMLPASAPAPAAAAGATAAGPTPPATGFGGFPPYLVGGGGPGIGFGSGQSAHAK
HHHHCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHH
AAASDSAAAESAAQASARAQARAARRGRSAAKARGHRDEFVTMDMGFDAAAPAPEHQPGA
HHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCC
RASDCGAGPIGFAGTVRKEAVVKAAGLTTLAGDDFGGGPTMPMMPGTWTHDQGVFDEHR
CCCCCCCCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036